MX2021012106A - Factores de coagulacion de accion prolongada y metodos de produccion de los mismos. - Google Patents

Factores de coagulacion de accion prolongada y metodos de produccion de los mismos.

Info

Publication number
MX2021012106A
MX2021012106A MX2021012106A MX2021012106A MX2021012106A MX 2021012106 A MX2021012106 A MX 2021012106A MX 2021012106 A MX2021012106 A MX 2021012106A MX 2021012106 A MX2021012106 A MX 2021012106A MX 2021012106 A MX2021012106 A MX 2021012106A
Authority
MX
Mexico
Prior art keywords
methods
long
coagulation factors
producing same
acting coagulation
Prior art date
Application number
MX2021012106A
Other languages
English (en)
Inventor
Udi Eyal Fima
Gili Hart
Original Assignee
Opko Biologics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opko Biologics Ltd filed Critical Opko Biologics Ltd
Publication of MX2021012106A publication Critical patent/MX2021012106A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
    • C07K2319/91—Fusion polypeptide containing a motif for post-translational modification containing a motif for glycosylation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Glass Compositions (AREA)

Abstract

Se describen polipéptidos y polinucleótidos que codifican los mismos que comprenden al menos un péptido en terminal carboxi (CTP) de la gonadotrofina coriónica unida a una terminación carboxi de un factor de coagulación. También se describen las composiciones farmacéuticas que comprenden los polipéptidos y polinucleótidos de la invención y métodos de uso de las mismas.
MX2021012106A 2009-07-09 2012-01-09 Factores de coagulacion de accion prolongada y metodos de produccion de los mismos. MX2021012106A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22436609P 2009-07-09 2009-07-09

Publications (1)

Publication Number Publication Date
MX2021012106A true MX2021012106A (es) 2022-06-14

Family

ID=43429620

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2014010834A MX346920B (es) 2009-07-09 2010-07-01 Factores de coagulacion de accion prolongada y metodos de produccion de los mismos.
MX2012000469A MX2012000469A (es) 2009-07-09 2010-07-01 Factores de coagulacion de accion prolongada y metodos de produccion de los mismos.
MX2021012106A MX2021012106A (es) 2009-07-09 2012-01-09 Factores de coagulacion de accion prolongada y metodos de produccion de los mismos.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2014010834A MX346920B (es) 2009-07-09 2010-07-01 Factores de coagulacion de accion prolongada y metodos de produccion de los mismos.
MX2012000469A MX2012000469A (es) 2009-07-09 2010-07-01 Factores de coagulacion de accion prolongada y metodos de produccion de los mismos.

Country Status (19)

Country Link
US (1) US8476234B2 (es)
EP (2) EP3130346A1 (es)
JP (3) JP5823960B2 (es)
KR (3) KR101950961B1 (es)
CN (2) CN102639144B (es)
AU (1) AU2010269884B2 (es)
CA (1) CA2767503C (es)
CY (1) CY1118733T1 (es)
DK (1) DK2451473T3 (es)
ES (1) ES2618209T3 (es)
HR (1) HRP20170051T1 (es)
HU (1) HUE032973T2 (es)
IL (2) IL235377A (es)
LT (1) LT2451473T (es)
MX (3) MX346920B (es)
PL (1) PL2451473T3 (es)
PT (1) PT2451473T (es)
SI (1) SI2451473T1 (es)
WO (1) WO2011004361A2 (es)

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CA2767503A1 (en) 2011-01-13
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