MX2021001972A - Dispositivos y metodos para prueba de diagnostico molecular. - Google Patents

Dispositivos y metodos para prueba de diagnostico molecular.

Info

Publication number
MX2021001972A
MX2021001972A MX2021001972A MX2021001972A MX2021001972A MX 2021001972 A MX2021001972 A MX 2021001972A MX 2021001972 A MX2021001972 A MX 2021001972A MX 2021001972 A MX2021001972 A MX 2021001972A MX 2021001972 A MX2021001972 A MX 2021001972A
Authority
MX
Mexico
Prior art keywords
module
amplification
molecular diagnostic
amplification module
input sample
Prior art date
Application number
MX2021001972A
Other languages
English (en)
Inventor
Jesus Ching
Boris Andreyev
La Zerda Adam De
David Swenson
Victor Briones
Colin Kelly
Steve Chu
Gregory Loney
Brian Ciopyk
Helen Huang
Keith Moravick
Original Assignee
Visby Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visby Medical Inc filed Critical Visby Medical Inc
Publication of MX2021001972A publication Critical patent/MX2021001972A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5029—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures using swabs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/028—Modular arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0672—Integrated piercing tool
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883—Serpentine channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1838—Means for temperature control using fluid heat transfer medium
    • B01L2300/1844—Means for temperature control using fluid heat transfer medium using fans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457—Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0605—Valves, specific forms thereof check valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0605—Valves, specific forms thereof check valves
    • B01L2400/0611—Valves, specific forms thereof check valves duck bill valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/527—Containers specially adapted for storing or dispensing a reagent for a plurality of reagents

Abstract

Un dispositivo de sujetador manual de prueba de diagnóstico molecular que incluye un alojamiento, un módulo de amplificación (o PCR), y un módulo de detección. El módulo de amplificación es configurado para recibir una muestra de entrada, y define un volumen de reacción. El módulo de amplificación incluye un calentador de modo que el módulo de amplificación pueda efectuar una reacción en cadena de la polimerasa (PCR) sobre la muestra de entrada. El módulo de detección es configurado para recibir una salida del módulo de amplificación y un reactivo formulado para producir una señal que indica la presencia de un amplicón blanco dentro de la muestra de entrada. El módulo de amplificación y el módulo de detección son integrados dentro del alojamiento.
MX2021001972A 2014-12-31 2017-06-28 Dispositivos y metodos para prueba de diagnostico molecular. MX2021001972A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462098769P 2014-12-31 2014-12-31
US201562213291P 2015-09-02 2015-09-02

Publications (1)

Publication Number Publication Date
MX2021001972A true MX2021001972A (es) 2021-04-28

Family

ID=56163504

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017008618A MX2017008618A (es) 2014-12-31 2015-12-30 Dispositivos y métodos para prueba de diagnóstico molecular.
MX2021001972A MX2021001972A (es) 2014-12-31 2017-06-28 Dispositivos y metodos para prueba de diagnostico molecular.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2017008618A MX2017008618A (es) 2014-12-31 2015-12-30 Dispositivos y métodos para prueba de diagnóstico molecular.

Country Status (10)

Country Link
US (12) US9623415B2 (es)
EP (2) EP4029606A1 (es)
JP (2) JP6778194B2 (es)
CN (2) CN107429281B (es)
AU (2) AU2015373998A1 (es)
CA (1) CA2972587A1 (es)
ES (1) ES2898103T3 (es)
HK (1) HK1246826A1 (es)
MX (2) MX2017008618A (es)
WO (1) WO2016109691A1 (es)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015138343A1 (en) 2014-03-10 2015-09-17 Click Diagnostics, Inc. Cartridge-based thermocycler
WO2016109691A1 (en) 2014-12-31 2016-07-07 Boris Andreyev Devices and methods for molecular diagnostic testing
USD775363S1 (en) * 2015-07-24 2016-12-27 Cepheid Molecular diagnostic system
US9646468B2 (en) * 2015-08-14 2017-05-09 Molecular Devices, Llc Sample-processing system with status lights
WO2017185067A1 (en) 2016-04-22 2017-10-26 Click Diagnostics, Inc. Printed circuit board heater for an amplification module
WO2017197040A1 (en) 2016-05-11 2017-11-16 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
MX2018015889A (es) 2016-06-29 2019-05-27 Click Diagnostics Inc Dispositivos y metodos para la deteccion de moleculas usando una celda de flujo.
USD800331S1 (en) 2016-06-29 2017-10-17 Click Diagnostics, Inc. Molecular diagnostic device
CA3029682A1 (en) * 2016-06-30 2018-01-04 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
USD800914S1 (en) 2016-06-30 2017-10-24 Click Diagnostics, Inc. Status indicator for molecular diagnostic device
WO2018122852A1 (en) * 2016-12-29 2018-07-05 Schnell Amit Cartridge for use in in-vitro diagnostics and method of use thereof
US11346850B2 (en) 2017-06-21 2022-05-31 Gyntools Ltd Assay system including assay apparatus and handheld single use assay devices for use therewith
EP3665466A4 (en) * 2017-08-07 2021-05-05 O.I. Corporation FLOW INTERRUPTION WITH PULSING INJECTION TECHNOLOGY FOR ANALYZER OF TOTAL ORGANIC CARBON (TOCA) BY HIGH TEMPERATURE COMBUSTION
TWI650545B (zh) * 2017-08-22 2019-02-11 研能科技股份有限公司 致動傳感模組
CN107653300A (zh) * 2017-11-02 2018-02-02 浙江大学 测定土壤样品dna提取率的方法
WO2019094784A1 (en) * 2017-11-09 2019-05-16 Click Diagnostics, Inc. Portable molecular diagnostic device and methods for the detection of target viruses
WO2019113261A1 (en) * 2017-12-06 2019-06-13 Entopsis Llc Separation device, and method of use, to remove pcr inhibitors from whole blood and serum samples
SG11201903333SA (en) 2017-12-29 2019-08-27 Clear Labs Inc Automated priming and library loading services
EP3774049A4 (en) * 2018-04-06 2022-01-05 Redbud Labs, Inc. MAGNETIC-BASED ACTUATION MECHANISMS AND METHODS FOR ACTUATING MAGNETICALLY RESPECTIVE MICRO-COLUMNS IN A REACTION CHAMBER
WO2020035767A1 (en) * 2018-08-13 2020-02-20 Beckman Coulter Inc. Laboratory instrument for testing patient sample
KR101996617B1 (ko) * 2018-10-11 2019-07-04 주식회사 엘지화학 일체형 카트리지
CN111218383A (zh) * 2018-11-26 2020-06-02 杭州比格飞序生物科技有限公司 一种核酸提取装置及其方法
US20210129153A1 (en) * 2018-11-30 2021-05-06 Illumina, Inc. Systems and methods for active warming of a cartridge
DE102018130834A1 (de) * 2018-12-04 2020-06-04 Endress+Hauser Conducta Gmbh+Co. Kg Durchströmbare Messstelle
CN113396326A (zh) * 2018-12-19 2021-09-14 核酸有限责任公司 用于分子诊断的设备和方法
AU2020265586A1 (en) * 2019-04-28 2021-10-14 Visby Medical, Inc. Molecular diagnostic devices with digital detection capability and wireless connectivity
IL267301A (en) 2019-06-12 2019-11-28 Gyntools Ltd A test device and hand-held sample collection tools for it
US11008627B2 (en) 2019-08-15 2021-05-18 Talis Biomedical Corporation Diagnostic system
CN110743634B (zh) * 2019-09-20 2021-06-01 华南农业大学 一种微流控设备
US20210121875A1 (en) * 2019-10-29 2021-04-29 Quantum-Si Incorporated Peristaltic pumping of fluids for bioanalytical applications and associated methods, systems, and devices
CN116457646A (zh) 2019-10-30 2023-07-18 吉恩工具有限公司 包含测定设备和与测定设备一起使用的手持式一次性使用测定装置的测定系统
WO2021138544A1 (en) * 2020-01-03 2021-07-08 Visby Medical, Inc. Devices and methods for antibiotic susceptibility testing
WO2021189064A1 (en) * 2020-03-16 2021-09-23 Siemens Healthcare Diagnostics Inc. Sample holders, pcr station assemblies, and methods of operating pcr testing systems
CN111575152B (zh) * 2020-05-27 2023-09-08 合肥中科易康达生物医学有限公司 一种集成核酸提取扩增检测功能于一体的封闭式卡盒及检测方法
EP4178721A1 (en) * 2020-07-08 2023-05-17 Lumacyte, Inc. Sampling device and systems
WO2022070662A1 (ja) * 2020-09-29 2022-04-07 富士フイルム株式会社 検査容器、検査装置及び核酸検査方法
EP4228813A1 (fr) 2020-10-26 2023-08-23 NAVARRO, Thierry Dispositif d'amplification d'adn ou arn et procede
CN112958173B (zh) * 2021-03-04 2023-01-10 深圳市美好创亿医疗科技股份有限公司 一种微流控试剂盒
US11432538B1 (en) * 2021-05-05 2022-09-06 The Florida International University Board Of Trustees Blood-feeding systems and methods for hematophagous arthropods
TWI785636B (zh) 2021-06-07 2022-12-01 新加坡商克雷多生醫有限公司 檢測卡匣
KR102375252B1 (ko) * 2021-06-29 2022-03-18 에스디바이오센서 주식회사 외측 챔버와 비드 챔버가 결합된 이중 챔버 구조의 유전체 추출 장치
KR102362853B1 (ko) * 2021-08-13 2022-02-15 에스디바이오센서 주식회사 내측 챔버와 결합되는 안전 클립을 포함하는 유전체 추출 장치
US11919004B2 (en) * 2021-08-30 2024-03-05 Wisconsin Alumni Research Foundation One-step sample extraction cassette and method for point-of-care molecular testing
EP4147647A1 (en) * 2021-09-14 2023-03-15 Kures S.r.l. Urine analysis device
RU210215U1 (ru) * 2021-10-15 2022-04-01 Федеральное государственное бюджетное учреждение «Федеральный научно-клинический центр физико-химической медицины Федерального медико-биологического агентства» Анализатор для проведения изотермической амплификации нуклеиновых кислот
CN114164091A (zh) * 2021-12-07 2022-03-11 广东润鹏生物技术有限公司 分子诊断样本处理系统及控制方法
WO2023216184A1 (zh) * 2022-05-12 2023-11-16 广州国家实验室 一种核酸扩增用卡盒
WO2023244945A1 (en) * 2022-06-13 2023-12-21 University Of Washington Diagnostic system including a base and single-use fluidic disposables

Family Cites Families (301)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697227A (en) 1966-05-13 1972-10-10 Westinghouse Electric Corp Chemical constituent sampler
US4710355A (en) 1984-06-14 1987-12-01 Olympus Optical Co., Ltd. Reagent delivery device
US4889692A (en) 1984-11-05 1989-12-26 Holtzman Marc E Disposable sample preparation container
USRE33858E (en) 1985-01-25 1992-03-24 Mallinckrodt Sensor Systems Inc. Apparatus for measuring a chemical entity in a liquid
IE64511B1 (en) 1988-03-11 1995-08-09 Takeda Chemical Industries Ltd Automated synthesizing apparatus
US6645758B1 (en) * 1989-02-03 2003-11-11 Johnson & Johnson Clinical Diagnostics, Inc. Containment cuvette for PCR and method of use
US5229297A (en) 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
US5270183A (en) 1991-02-08 1993-12-14 Beckman Research Institute Of The City Of Hope Device and method for the automated cycling of solutions between two or more temperatures
US5273905A (en) 1991-02-22 1993-12-28 Amoco Corporation Processing of slide mounted material
US7297313B1 (en) 1991-08-31 2007-11-20 The Regents Of The University Of California Microfabricated reactor, process for manufacturing the reactor, and method of amplification
US5587128A (en) 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US5726026A (en) 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5498392A (en) 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
DE69302692T2 (de) 1992-07-06 1996-10-02 Beckman Instruments Inc Flüssigkeitsversorgungssystem mit Mehrwegventil
US5503985A (en) 1993-02-18 1996-04-02 Cathey; Cheryl A. Disposable device for diagnostic assays
US5429807A (en) 1993-10-28 1995-07-04 Beckman Instruments, Inc. Method and apparatus for creating biopolymer arrays on a solid support surface
US5631165A (en) 1994-08-01 1997-05-20 Abbott Laboratories Method for performing automated hematology and cytometry analysis
WO1996014934A1 (en) * 1994-11-14 1996-05-23 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5633168A (en) 1995-06-07 1997-05-27 Glasscock; Larry M. Controlled dispersion flow analysis system
US20050100946A1 (en) 1995-06-29 2005-05-12 Affymetrix, Inc. Integrated nucleic acid diagnostic device and method for in-situ confocal microscopy
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US6153425A (en) 1995-07-13 2000-11-28 Xtrana, Inc. Self-contained device integrating nucleic acid extraction, amplification and detection
US5773234A (en) 1995-08-07 1998-06-30 Quidel Corporation Method and device for chlamydia detection
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
AU6720096A (en) 1995-08-09 1997-03-05 Quidel Corporation Test strip and method for one step lateral flow assay
US7244622B2 (en) 1996-04-03 2007-07-17 Applera Corporation Device and method for multiple analyte detection
ATE428801T1 (de) 1996-06-04 2009-05-15 Univ Utah Res Found Überwachung der hybridisierung während pcr
US5800784A (en) 1996-07-09 1998-09-01 Horn; Marcus J. Chemical sample treatment system and cassette, and methods for effecting multistep treatment process
US5882903A (en) 1996-11-01 1999-03-16 Sarnoff Corporation Assay system and method for conducting assays
DE29623597U1 (de) 1996-11-08 1999-01-07 Eppendorf Geraetebau Netheler Temperierblock mit Temperiereinrichtungen
US5952664A (en) 1997-01-17 1999-09-14 Imaging Diagnostic Systems, Inc. Laser imaging apparatus using biomedical markers that bind to cancer cells
US6924153B1 (en) 1997-03-06 2005-08-02 Quidel Corporation Quantitative lateral flow assays and devices
US6126804A (en) 1997-09-23 2000-10-03 The Regents Of The University Of California Integrated polymerase chain reaction/electrophoresis instrument
EP1179585B1 (en) 1997-12-24 2008-07-09 Cepheid Device and method for lysis
US6369893B1 (en) 1998-05-19 2002-04-09 Cepheid Multi-channel optical detection system
US6303081B1 (en) 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US6146591A (en) 1998-05-01 2000-11-14 Miller; C David Biochemical detection system for rapid determination of the presence of toxins, bacteria, and other substances
US5976470A (en) 1998-05-29 1999-11-02 Ontogen Corporation Sample wash station assembly
US6780617B2 (en) 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
US7799521B2 (en) 1998-06-24 2010-09-21 Chen & Chen, Llc Thermal cycling
US6313471B1 (en) 1998-08-18 2001-11-06 Molecular Devices Corporation Scanning fluorometer
US20010055799A1 (en) 1998-12-15 2001-12-27 David Baunoch Method and apparatus for automated reprocessing of tissue samples
US6261431B1 (en) 1998-12-28 2001-07-17 Affymetrix, Inc. Process for microfabrication of an integrated PCR-CE device and products produced by the same
US6235479B1 (en) 1999-04-13 2001-05-22 Bio Merieux, Inc. Methods and devices for performing analysis of a nucleic acid sample
US20020177135A1 (en) * 1999-07-27 2002-11-28 Doung Hau H. Devices and methods for biochip multiplexing
CA2374423C (en) 1999-05-28 2013-04-09 Cepheid Apparatus and method for analyzing a liquid sample
GB9922971D0 (en) 1999-09-29 1999-12-01 Secr Defence Reaction system
JP2001186881A (ja) 1999-10-22 2001-07-10 Ngk Insulators Ltd Ｄｎａチップの製造方法
US6699713B2 (en) 2000-01-04 2004-03-02 The Regents Of The University Of California Polymerase chain reaction system
FR2812306B1 (fr) 2000-07-28 2005-01-14 Gabriel Festoc Systeme d'amplification en chaine par polymerse de sequences nucleiques cibles
US6374684B1 (en) 2000-08-25 2002-04-23 Cepheid Fluid control and processing system
US8048386B2 (en) 2002-02-25 2011-11-01 Cepheid Fluid processing and control
US6610499B1 (en) 2000-08-31 2003-08-26 The Regents Of The University Of California Capillary array and related methods
US6680617B2 (en) 2000-09-20 2004-01-20 Neocera, Inc. Apertured probes for localized measurements of a material's complex permittivity and fabrication method
US6911181B1 (en) 2000-10-03 2005-06-28 Isis Pharmaceuticals, Inc. Self-dispensing storage device
SE0004297D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device for thermal cycling
US6780380B2 (en) 2001-01-16 2004-08-24 Triangle Biomedical Sciences, Inc. Tissue processor
US20020168780A1 (en) 2001-02-09 2002-11-14 Shaorong Liu Method and apparatus for sample injection in microfabricated devices
US6426215B1 (en) 2001-04-06 2002-07-30 Pe Corporation (Ny) PCR plate cover and maintaining device
US6905885B2 (en) 2001-06-12 2005-06-14 The Regents Of The University Of California Portable pathogen detection system
US20040018502A1 (en) 2001-06-14 2004-01-29 Yoshihiko Makino Method for analyzing a target nucleic acid fragment and a kit for analyzing a target nucleic acid fragment
JP3705499B2 (ja) * 2001-06-14 2005-10-12 富士写真フイルム株式会社 ターゲット核酸断片の分析方法及びターゲット核酸断片の分析キット
US6514750B2 (en) 2001-07-03 2003-02-04 Pe Corporation (Ny) PCR sample handling device
ATE522776T1 (de) 2001-07-16 2011-09-15 Idaho Technology Inc Temperaturwechselsystem und verwendungsverfahren
US7265833B2 (en) 2001-07-25 2007-09-04 Applera Corporation Electrophoretic system with multi-notch filter and laser excitation source
US7280207B2 (en) 2001-07-25 2007-10-09 Applera Corporation Time-delay integration in a flow cytometry system
AUPR707101A0 (en) 2001-08-16 2001-09-06 Corbett Research Pty Ltd Continuous flow thermal device
US6855561B2 (en) 2001-09-10 2005-02-15 Quidel Corporation Method for adding an apparent non-signal line to a lateral flow assay
US7879293B2 (en) 2001-09-28 2011-02-01 Orasure Technologies, Inc. Sample collector and test device
CA2462332C (en) 2001-10-01 2014-12-09 Vision Biosystems Limited Histological tissue specimen treatment
WO2003029397A1 (en) 2001-10-02 2003-04-10 Stratagene Side-wall heater for thermocycler device
US7691333B2 (en) 2001-11-30 2010-04-06 Fluidigm Corporation Microfluidic device and methods of using same
US20030116552A1 (en) 2001-12-20 2003-06-26 Stmicroelectronics Inc. Heating element for microfluidic and micromechanical applications
US6813568B2 (en) 2002-01-09 2004-11-02 Memorial Sloan-Kettering Cancer Center System and process for microfluidics-based automated chemistry
US6677151B2 (en) 2002-01-30 2004-01-13 Applera Corporation Device and method for thermal cycling
US8030000B2 (en) 2002-02-21 2011-10-04 Alere San Diego, Inc. Recombinase polymerase amplification
JP3892743B2 (ja) 2002-03-01 2007-03-14 日本碍子株式会社 反応セルおよびその使用方法
US7179639B2 (en) 2002-03-05 2007-02-20 Raveendran Pottathil Thermal strip thermocycler
EP1376131A1 (en) 2002-06-27 2004-01-02 Inverness Medical Switzerland GmbH Assay device for liquid sample
JP4013671B2 (ja) 2002-07-05 2007-11-28 松下電器産業株式会社 ポリメラーゼ連鎖反応容器及びその製造方法
US7452712B2 (en) 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
US7449302B2 (en) 2002-10-02 2008-11-11 The University Of Bristol, University Walk Therapeutic peptides
US7291459B2 (en) 2002-12-10 2007-11-06 University Of Alabama At Huntsville Nucleic acid detector and method of detecting targets within a sample
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
JP2006520190A (ja) 2003-01-21 2006-09-07 マイクロニクス， インコーポレイテッド 流体の微小流体的な操作、増幅、および分析（例えば、細菌アッセイおよびアンチグロブリン試験）のための方法およびシステム
US6901217B2 (en) 2003-02-28 2005-05-31 Motorolr, Inc. Conduits integrated in circuit board and method of manufacture
US6781056B1 (en) 2003-02-28 2004-08-24 Motorola, Inc. Heater for temperature control integrated in circuit board and method of manufacture
US7041481B2 (en) 2003-03-14 2006-05-09 The Regents Of The University Of California Chemical amplification based on fluid partitioning
US7151270B2 (en) 2003-05-02 2006-12-19 Leica Microsystems Cms Gmbh Method for classifying object image regions of an object to be detected using a scanning microscope
US7148043B2 (en) 2003-05-08 2006-12-12 Bio-Rad Laboratories, Inc. Systems and methods for fluorescence detection with a movable detection module
US7648835B2 (en) 2003-06-06 2010-01-19 Micronics, Inc. System and method for heating, cooling and heat cycling on microfluidic device
CA2956645A1 (en) 2003-07-12 2005-03-31 David A. Goldberg Sensitive and rapid biodetection
US7517495B2 (en) 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
US7491527B2 (en) * 2003-09-19 2009-02-17 Microfluidic Systems, Inc. Microfluidic differential extraction cartridge
JP4933258B2 (ja) 2003-09-22 2012-05-16 クイデル コーポレーション 試料中の複数分析物の検出装置
NZ547175A (en) 2003-11-14 2009-11-27 Oakville Hong Kong Co Ltd Sample collection cup with integrated sample analysis system
AU2004291923B2 (en) 2003-11-14 2011-01-20 Alere Switzerland Gmbh Sample collection cup with integrated activatable sample analysis system
WO2005050167A2 (en) 2003-11-14 2005-06-02 Oakville Hong Kong Co., Limited Rapid sample collection and analysis device
US7767439B2 (en) 2003-12-10 2010-08-03 Samsung Electronics Co., Ltd. Real-time PCR monitoring apparatus and method
KR100750586B1 (ko) 2003-12-26 2007-08-20 한국전자통신연구원 미소유체 가열 시스템
WO2005080606A1 (en) 2004-02-18 2005-09-01 Xiaochuan Zhou Fluidic devices and methods for multiplex chemical and biochemical reactions
EP1716404A4 (en) 2004-02-20 2010-05-05 Univ New York State Res Found METHOD AND DEVICE FOR HANDLING LIQUIDS IN MICROFLUIDIC SYSTEMS
KR100552706B1 (ko) 2004-03-12 2006-02-20 삼성전자주식회사 핵산 증폭 방법 및 장치
WO2005095967A1 (en) 2004-03-23 2005-10-13 Quidel Corporation Hybrid phase lateral flow assay
CA2562775C (en) 2004-04-07 2015-08-04 Access Bio, Inc. Nucleic acid detection system
CA2502549C (en) 2004-04-23 2016-02-16 Becton, Dickinson And Company Use of an extraction control in a method of extracting nucleic acids
EP1598429A1 (en) 2004-05-19 2005-11-23 Amplion Ltd. Detection of amplicon contamination during PCR exhibiting two different annealing temperatures
US7871143B2 (en) 2004-06-30 2011-01-18 Lexmark International, Inc. Ground structure for temperature-sensing resistor noise reduction
US7662562B2 (en) 2004-08-10 2010-02-16 Becton, Dickinson And Company Method for rapid identification of microorganisms
US7192721B1 (en) 2004-08-26 2007-03-20 Chembio Diagnostic Systems, Inc. Universal rapid test and method for detection of tuberculosis in multiple host species
US7592139B2 (en) 2004-09-24 2009-09-22 Sandia National Laboratories High temperature flow-through device for rapid solubilization and analysis
EP2927238B1 (en) 2004-10-18 2018-01-17 Brandeis University Methods for LATE amplification and sequencing of a nucleic acid
JP4999103B2 (ja) 2004-10-27 2012-08-15 セフィード 閉鎖系の多段階核酸増幅反応
US8883487B2 (en) 2004-12-23 2014-11-11 Abbott Point Of Care Inc. Molecular diagnostics system and methods
KR100601982B1 (ko) 2005-01-20 2006-07-18 삼성전자주식회사 흡열반응을 통한 가열-냉각 과정에 의한 세포 용해 방법
CN101146595B (zh) 2005-01-28 2012-07-04 杜克大学 用于在印刷电路板上操作液滴的装置和方法
WO2006094149A2 (en) 2005-03-01 2006-09-08 Exact Sciences Corporation Methods and compositions for detecting adenoma
US7189522B2 (en) 2005-03-11 2007-03-13 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
US20060246493A1 (en) * 2005-04-04 2006-11-02 Caliper Life Sciences, Inc. Method and apparatus for use in temperature controlled processing of microfluidic samples
US20070026391A1 (en) 2005-04-11 2007-02-01 Ghc Technologies, Inc. Methods and compositions for identifying chemical or biological agents using multiplexed labeling and colocalization detection
US7235216B2 (en) 2005-05-01 2007-06-26 Iba Molecular North America, Inc. Apparatus and method for producing radiopharmaceuticals
KR100695148B1 (ko) 2005-05-02 2007-03-14 삼성전자주식회사 중합효소 연쇄반응용 모듈 및 이를 채용한 다중 중합효소 연쇄반응 장치
US20070042427A1 (en) 2005-05-03 2007-02-22 Micronics, Inc. Microfluidic laminar flow detection strip
CA2607661C (en) 2005-05-09 2017-08-08 Idaho Technology, Inc. A device and method for two-stage nucleic acid amplification
AU2006247752B2 (en) 2005-05-11 2012-04-12 Advanced Liquid Logic, Inc. Method and device for conducting biochemical or chemical reactions at multiple temperatures
WO2006122311A2 (en) 2005-05-11 2006-11-16 The Trustees Of The University Of Pennsylvania Microfluidic chip
US8377398B2 (en) * 2005-05-31 2013-02-19 The Board Of Regents Of The University Of Texas System Methods and compositions related to determination and use of white blood cell counts
EP2508867A1 (en) 2005-06-24 2012-10-10 Board Of Regents, The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
TW200714898A (en) 2005-08-02 2007-04-16 3M Innovative Properties Co Apparatus and method for detecting an analyte
US7618588B2 (en) 2005-08-10 2009-11-17 Microfluidic Systems, Inc. Disposable integrated heater and tube assembly for thermally-driven chemical reactions
US7569382B2 (en) 2005-10-05 2009-08-04 Instantlabs Medical Diagnostic Corp. Disposable reactor module and detection system
WO2007047336A2 (en) 2005-10-12 2007-04-26 University Of Virginia Patent Foundation Integrated microfluidic analysis systems
US7754148B2 (en) * 2006-12-27 2010-07-13 Progentech Limited Instrument for cassette for sample preparation
CN100478671C (zh) 2005-10-25 2009-04-15 艾康生物技术(杭州)有限公司 用于液体样本的检测装置和方法
US7858396B2 (en) 2005-10-31 2010-12-28 Orasure Technologies, Inc. Lateral flow assay device with multiple equidistant capture zones
US8871155B2 (en) 2005-11-30 2014-10-28 Alere Switzerland Gmbh Devices for detecting analytes in fluid sample
WO2007078833A2 (en) 2005-12-16 2007-07-12 The Curators Of The University Of Missouri Reusable pcr amplification system and method
US7959877B2 (en) 2005-12-22 2011-06-14 Chembio Diagnostic Systems, Inc. Immunoassay apparatus and kit
US7377291B2 (en) 2005-12-28 2008-05-27 Serveron Corporation Multiport rotary valve
US8703445B2 (en) * 2005-12-29 2014-04-22 Abbott Point Of Care Inc. Molecular diagnostics amplification system and methods
US7871568B2 (en) 2006-01-23 2011-01-18 Quidel Corporation Rapid test apparatus
US7794656B2 (en) 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
US20080050735A1 (en) 2006-02-01 2008-02-28 Elena Pushnova Nucleic acid testing method for point-of-care diagnostics and genetic self-monitoring
GB0603965D0 (en) 2006-02-28 2006-04-05 Centeo Biosciences Ltd Incubator apparatus and method
WO2007106579A2 (en) 2006-03-15 2007-09-20 Micronics, Inc. Integrated nucleic acid assays
JP5415253B2 (ja) * 2006-03-24 2014-02-12 ハンディラブ・インコーポレーテッド 微小流体サンプルを処理するための一体化システム及びその使用方法
US8088616B2 (en) 2006-03-24 2012-01-03 Handylab, Inc. Heater unit for microfluidic diagnostic system
EP2016611A2 (en) 2006-04-25 2009-01-21 University Of South Florida Portable reactor for real-time nucleic acid amplification and detection
US8900828B2 (en) 2006-05-01 2014-12-02 Cepheid Methods and apparatus for sequential amplification reactions
US8232091B2 (en) 2006-05-17 2012-07-31 California Institute Of Technology Thermal cycling system
US8137626B2 (en) * 2006-05-19 2012-03-20 California Institute Of Technology Fluorescence detector, filter device and related methods
US20080153078A1 (en) 2006-06-15 2008-06-26 Braman Jeffrey C System for isolating biomolecules from a sample
US20080026451A1 (en) 2006-06-15 2008-01-31 Braman Jeffrey C System for isolating biomolecules from a sample
AU2007265628B2 (en) 2006-06-23 2012-12-06 Perkinelmer Health Sciences, Inc. Methods and devices for microfluidic point-of-care immunoassays
US8163535B2 (en) 2006-06-26 2012-04-24 Blood Cell Storage, Inc. Devices and processes for nucleic acid extraction
US7629124B2 (en) 2006-06-30 2009-12-08 Canon U.S. Life Sciences, Inc. Real-time PCR in micro-channels
US8187557B2 (en) 2006-07-13 2012-05-29 Cepheid Reagent reservoir system for analytical instruments
EP1878802A1 (en) 2006-07-14 2008-01-16 Roche Diagnostics GmbH Disposable device for analysing a liquid sample containing a nucleic acid with a nucleic acid amplification apparatus
US20090047673A1 (en) 2006-08-22 2009-02-19 Cary Robert B Miniaturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids
US8980561B1 (en) 2006-08-22 2015-03-17 Los Alamos National Security, Llc. Nucleic acid detection system and method for detecting influenza
GB0617035D0 (en) 2006-08-30 2006-10-11 Inverness Medical Switzerland Fluidic indicator device
GB0718250D0 (en) 2007-08-29 2007-10-31 B G Res Ltd Improvements in and relating to reaction apparatus
US7985716B2 (en) 2006-09-22 2011-07-26 Uchicago Argonne, Llc Nucleic acid sample purification and enrichment with a thermo-affinity microfluidic sub-circuit
WO2008147382A1 (en) 2006-09-27 2008-12-04 Micronics, Inc. Integrated microfluidic assay devices and methods
EP2082061B8 (en) 2006-10-06 2020-10-07 Applied DNA Sciences, Inc. Method for a continuous rapid thermal cycle system
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
WO2008061165A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic cartridge and method of making same
US8263392B2 (en) 2006-11-14 2012-09-11 University Of Utah Research Foundation Methods and compositions related to continuous flow thermal gradient PCR
US8735103B2 (en) 2006-12-05 2014-05-27 Electronics And Telecommunications Research Institute Natural convection-driven PCR apparatus and method using disposable polymer chip
GB0625309D0 (en) 2006-12-19 2007-01-24 Inverness Medical Switzerland Device
US8338166B2 (en) 2007-01-04 2012-12-25 Lawrence Livermore National Security, Llc Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
EP2111209B1 (en) 2007-01-22 2022-05-04 OraSure Technologies, Inc. Container and method for supporting home testing and diagnosis of infectious diseases
WO2008115626A2 (en) 2007-02-05 2008-09-25 Microchip Biotechnologies, Inc. Microfluidic and nanofluidic devices, systems, and applications
US8298763B2 (en) 2007-03-02 2012-10-30 Lawrence Livermore National Security, Llc Automated high-throughput flow-through real-time diagnostic system
CA2984820C (en) 2007-04-04 2021-12-07 Ande Corporation Plastic microfluidic separation and detection platforms
WO2008132871A1 (ja) 2007-04-13 2008-11-06 Shimadzu Corporation 反応容器プレート及び反応処理方法
JP4992524B2 (ja) 2007-04-13 2012-08-08 株式会社島津製作所 反応容器プレート及び反応処理方法
EP2152416A1 (en) 2007-04-20 2010-02-17 Quidel Corporation Analytical devices with intedrated desiccant
KR101228308B1 (ko) 2007-05-23 2013-01-31 삼성전자주식회사 미세유동 칩을 이용한 디스크형 미세유동장치 및 생체물질마이크로어레이 칩을 이용한 디스크형 미세유동장치
GB0710957D0 (en) 2007-06-07 2007-07-18 Norchip As A device for carrying out cell lysis and nucleic acid extraction
CA2691451C (en) 2007-06-21 2015-03-24 Sara H. Fan Instrument and receptacles for performing processes
JP5045268B2 (ja) 2007-06-28 2012-10-10 ソニー株式会社 反応処理装置
US8678239B2 (en) 2007-07-13 2014-03-25 The Coca-Cola Company Clean in place system for beverage dispensers
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8076129B2 (en) 2007-07-26 2011-12-13 Shimadzu Corporation Reactor plate and reaction processing method
EP2171420A1 (en) 2007-07-31 2010-04-07 Micronics, Inc. Sanitary swab collection system, microfluidic assay device, and methods for diagnostic assays
US7955840B2 (en) 2007-08-23 2011-06-07 Akonni Biosystems Thermal cycler for PCR including temperature control bladder
WO2009049268A1 (en) 2007-10-12 2009-04-16 Rheonix, Inc. Integrated microfluidic device and methods
CL2008003008A1 (es) 2007-10-12 2009-10-02 Bigtec Private Ltd Un micro dispositivo portatil de reaccion en cadena de polimerasa (pcr) basado en un micro chip de ceramica de coccion conjunta de baja temperatura (ltcc) que comprende camara de reaccion, calentador, control de temperatura del calentador, deteccion optica de interfaz de comunicacion, y el metodo para monitorearlo y controlarlo.
US8222048B2 (en) 2007-11-05 2012-07-17 Abbott Laboratories Automated analyzer for clinical laboratory
US8075854B2 (en) 2007-11-08 2011-12-13 The Ohio State University Research Foundation Bioprocessing Innovative Company Microfluidic chips for rapid multiplex ELISA
DE102007062441A1 (de) 2007-12-20 2009-06-25 Aj Innuscreen Gmbh Mobiles Schnelltestsystem für die Nukleinsäureanalytik
KR101465701B1 (ko) 2008-01-22 2014-11-28 삼성전자 주식회사 핵산 증폭 장치
WO2009108260A2 (en) * 2008-01-22 2009-09-03 Microchip Biotechnologies, Inc. Universal sample preparation system and use in an integrated analysis system
US20090186344A1 (en) 2008-01-23 2009-07-23 Caliper Life Sciences, Inc. Devices and methods for detecting and quantitating nucleic acids using size separation of amplicons
WO2009092564A2 (en) 2008-01-23 2009-07-30 Roche Diagnostics Gmbh Integrated instrument performing synthesis and amplification
US20090215050A1 (en) 2008-02-22 2009-08-27 Robert Delmar Jenison Systems and methods for point-of-care amplification and detection of polynucleotides
WO2009137055A1 (en) 2008-05-05 2009-11-12 Los Alamos National Security, Llc Nanocrystal-based lateral flow microarrays and low-voltage signal detection systems
EP2279403B1 (en) 2008-05-05 2016-03-16 Los Alamos National Security, LLC Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control
US20110313148A1 (en) 2008-07-23 2011-12-22 William Christ Automated oligosaccharide synthesizer
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
US9156010B2 (en) 2008-09-23 2015-10-13 Bio-Rad Laboratories, Inc. Droplet-based assay system
JP5743891B2 (ja) 2008-09-23 2015-07-01 コーニンクレッカ フィリップス エヌ ヴェ サーモサイクルデバイス
EP2172703A1 (en) 2008-10-03 2010-04-07 J & H ApS Emergency light device for marine environments
US8058005B2 (en) 2008-10-23 2011-11-15 Honeywell International Inc. Method for single nucleotide polymorphism and mutation detection using real time polymerase chain reaction microarray
CA2742598A1 (en) 2008-11-04 2010-05-14 Blood Cell Storage, Inc. Nucleic acid extraction on curved glass surfaces
US8110148B2 (en) 2008-11-06 2012-02-07 Siemens Medical Solutions Usa, Inc. Apparatus and method using rotary flow distribution mechanisms
JP5798487B2 (ja) 2008-11-20 2015-10-21 ネーデルランドセ・オルガニサティ・フォール・トゥーヘパスト−ナトゥールウェテンスハッペライク・オンデルズーク・テーエヌオー Ｆｒｅｔに基づく病原体の迅速診断
CN101556277B (zh) 2009-01-05 2012-12-26 艾博生物医药(杭州)有限公司 检测装置
US8058630B2 (en) 2009-01-16 2011-11-15 Fluidigm Corporation Microfluidic devices and methods
EP2391883B1 (en) 2009-01-30 2018-03-07 Micronics, Inc. Portable high gain fluorescence detection system
EP2406614A1 (en) 2009-03-10 2012-01-18 Agency For Science, Technology And Research Apparatus for processing a biological and/or chemical sample
KR101796906B1 (ko) 2009-03-24 2017-11-10 유니버시티 오브 시카고 반응을 수행하기 위한 방법
CA2761943A1 (en) 2009-05-14 2010-11-18 Streck, Inc. Sample processing cassette, system, and method
EP3360974A1 (en) 2009-06-05 2018-08-15 Alere San Diego, Inc. Recombinase polymerase amplification reagents
JP2012529268A (ja) 2009-06-05 2012-11-22 インテジェンクス，インコーポレイテッド ユニバーサルサンプル調製システムおよび統合解析システムの使用方法
US9475049B2 (en) 2009-07-31 2016-10-25 Invisible Sentinel, Inc. Analyte detection devices, multiplex and tabletop devices for detection of analyte, and uses thereof
US9625454B2 (en) 2009-09-04 2017-04-18 The Research Foundation For The State University Of New York Rapid and continuous analyte processing in droplet microfluidic devices
US8008080B2 (en) 2009-09-23 2011-08-30 Ecolab Usa Inc. Valve analytical system
EE201000013A (et) 2010-01-29 2011-10-17 Selfdiagnostics O� Meetod ja kiirtesti seade sihtm„rk-molekuli proovimaterjalist detekteerimiseks
WO2011106384A1 (en) 2010-02-23 2011-09-01 Genturadx, Inc. Apparatus and methods for integrated sample preparation, reaction and detection
US8791675B2 (en) 2010-03-22 2014-07-29 Pine Valley Investments, Inc. Mobile wireless communications device including removable electrical power supply module and related methods
US20110244466A1 (en) * 2010-04-02 2011-10-06 Robert Juncosa Nucleic acid testing device and method
SG184539A1 (en) 2010-04-09 2012-11-29 Life Technologies Corp Improved thermal uniformity for thermal cycler instrumentation using dynamic control
US8435737B2 (en) * 2010-06-02 2013-05-07 Cal Poly Corporation Primers for the rapid and specific detection of propane-oxidizing and butane-oxidizing microorganisms and methods of using same
US20110312709A1 (en) 2010-06-17 2011-12-22 Geneasys Pty Ltd Loc device for detecting target nucleic acid sequences using electrochemiluminescent probes and calibration probes with detection photosensors and calibration photosensors
KR20120020528A (ko) 2010-08-30 2012-03-08 삼성전자주식회사 중합효소 연쇄반응 장치
WO2012033765A1 (en) 2010-09-07 2012-03-15 The Arizona Board Of Regents On Behalf Of The University Of Arizona Microdroplet-manipulation systems and methods for automated execution of molecular biological protocols
WO2012039994A1 (en) 2010-09-22 2012-03-29 Corning Incorporated Microporous microfluidic device
US8795592B2 (en) 2010-09-23 2014-08-05 Analogic Corporation Sample thermal cycling
US8945843B2 (en) 2010-12-09 2015-02-03 Analogic Corporation Thermocooler with thermal breaks that thermally isolate a thermocycling region from at least one guard heat region
US8603835B2 (en) 2011-02-10 2013-12-10 Chembio Diagnostic Systems, Inc. Reduced step dual path immunoassay device and method
JP5977228B2 (ja) * 2011-03-04 2016-08-24 株式会社カネカ 核酸の検出方法及びその方法に用いるデバイス、キット
KR20140029404A (ko) 2011-03-23 2014-03-10 캘리포니아 인스티튜트 오브 테크놀로지 폴리메라아제 연쇄 반응 핵산 증폭을 수행하기 위한 시스템
US8911941B2 (en) 2011-04-14 2014-12-16 Kenneth J. Michlitsch Methods and apparatus for point-of-care nucleic acid amplification and detection
US9469871B2 (en) 2011-04-14 2016-10-18 Corporos Inc. Methods and apparatus for point-of-care nucleic acid amplification and detection
DK2699700T3 (en) 2011-04-20 2016-08-01 Mesa Biotech Inc Integrated device for nukleinsyreregistrering and identification
US9447456B2 (en) 2011-04-25 2016-09-20 University Of Notre Dame Du Lac Systems and methods for bead-free detection of nucleotides
WO2012151473A2 (en) 2011-05-04 2012-11-08 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
JP2012242118A (ja) 2011-05-16 2012-12-10 Canon Inc 流体デバイスを用いる熱処理装置、および流体の処理方法
WO2012159063A2 (en) 2011-05-19 2012-11-22 Blood Cell Strorage, Inc. Gravity flow fluidic device for nucleic acid extraction
US8347490B1 (en) 2011-06-30 2013-01-08 Chipbond Technology Corporation Method for fabricating a carrier with a three dimensional inductor
US9435765B2 (en) * 2011-07-22 2016-09-06 Tecan Trading Ag Cartridge and system for manipulating samples in liquid droplets
US20150258273A1 (en) 2011-08-31 2015-09-17 Forrest W. Payne Electrochemically-Actuated Microfluidic Devices
US9352312B2 (en) * 2011-09-23 2016-05-31 Alere Switzerland Gmbh System and apparatus for reactions
US8894946B2 (en) 2011-10-21 2014-11-25 Integenx Inc. Sample preparation, processing and analysis systems
EP2773892B1 (en) 2011-11-04 2020-10-07 Handylab, Inc. Polynucleotide sample preparation device
EP3517971A1 (en) 2011-11-11 2019-07-31 Icubate, Inc. Systems and methods for performing amplicon rescue multiplex polymerase chain reaction (pcr)
TWI582425B (zh) 2011-11-25 2017-05-11 凸版印刷股份有限公司 樣本分析晶片、樣本分析方法及基因解析方法
CN103184143A (zh) 2011-12-29 2013-07-03 三星电子株式会社 固体试剂溶解器件以及使用其溶解固体试剂的方法
WO2013112755A1 (en) 2012-01-24 2013-08-01 The Trustees Of Columbia University In The City Of New York Field optimized assay devices, methods, and systems
US9533308B2 (en) 2012-02-10 2017-01-03 California Institute Of Technology PC board-based polymerase chain reaction systems, methods and materials
US9322054B2 (en) * 2012-02-22 2016-04-26 Lockheed Martin Corporation Microfluidic cartridge
US9035204B2 (en) 2012-02-29 2015-05-19 Reliance Controls Corporation Switch assembly with sequentially actuated power and neutral switching
WO2013131057A1 (en) 2012-03-01 2013-09-06 Quidel Corporation System and apparatus for point-of-care diagnostics
WO2013132645A1 (ja) 2012-03-09 2013-09-12 独立行政法人産業技術総合研究所 核酸増幅方法
US9238833B2 (en) 2012-04-17 2016-01-19 California Institute Of Technology Thermally controlled chamber with optical access for high-performance PCR
US9150907B2 (en) 2012-04-27 2015-10-06 General Electric Company Microfluidic flow cell assemblies and method of use
US9044729B2 (en) 2012-07-27 2015-06-02 International Park Of Creativity Methods and devices for electromagnetic amplification of nucleic acids
CA2879729A1 (en) 2012-08-07 2014-02-13 California Institute Of Technology Ultrafast thermal cycler
US9387478B2 (en) 2012-08-17 2016-07-12 Lexmark International, Inc. Micro-fluidic modules on a chip for diagnostic applications
WO2014035986A1 (en) 2012-08-28 2014-03-06 Akonni Biosystems Inc. Method and kit for purifying nucleic acids
CN104737024B (zh) 2012-09-05 2018-01-09 塞弗德公司 流体分析系统中的通用对接站和数据门
US9686395B2 (en) 2012-09-11 2017-06-20 Cornell University Apparatus and method for point-of-collection measurement of a biomolecular reaction
US9580679B2 (en) 2012-09-21 2017-02-28 California Institute Of Technology Methods and devices for sample lysis
US20150290639A1 (en) 2012-12-03 2015-10-15 Vladimir Evtodienko Pressure assisted lateral flow diagnostic device
WO2014100725A1 (en) * 2012-12-21 2014-06-26 Micronics, Inc. Portable fluorescence detection system and microassay cartridge
WO2014112671A1 (ko) 2013-01-21 2014-07-24 나노바이오시스(주) 핵산 추출용 미세유동 칩, 이를 포함하는 핵산 추출 장치, 및 이를 이용하는 핵산 추출 방법
EP2946198B1 (en) 2013-01-21 2019-10-30 Cornell University Smartphone-based apparatus and method for obtaining repeatable, quantitative colorimetric measurement
US9995412B2 (en) 2013-03-01 2018-06-12 Wave 80 Biosciences, Inc. Long-throw microfluidic actuator
US9623409B2 (en) 2013-03-11 2017-04-18 Cue Inc. Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes
CN104707674B (zh) 2013-03-11 2018-06-15 克忧公司 用于检测和量化分析物的系统和方法
US20140274770A1 (en) 2013-03-13 2014-09-18 Quidel Corporation Pcr assays and reagents for molecular detection of infectious agents
AU2014228937A1 (en) 2013-03-15 2015-10-15 Nanobiosym, Inc. Systems and methods for mobile device analysis of nucleic acids and proteins
WO2014190258A1 (en) 2013-05-23 2014-11-27 The Regents Of The University Of California Proximal degas driven microfluidic actuation
WO2015019522A1 (ja) 2013-08-08 2015-02-12 パナソニック株式会社 核酸増幅デバイス、核酸増幅装置及び核酸増幅方法
EP3089823A4 (en) 2013-12-31 2017-12-20 Canon U.S. Life Sciences, Inc. Field deployable small format fast first result microfluidic system
US20180135108A1 (en) 2014-01-20 2018-05-17 Board Of Trustees Of Michigan State University Method for detecting bacterial and fungal pathogens
WO2015138343A1 (en) 2014-03-10 2015-09-17 Click Diagnostics, Inc. Cartridge-based thermocycler
US10767219B2 (en) 2014-03-11 2020-09-08 Illumina, Inc. Disposable, integrated microfluidic cartridge and methods of making and using same
WO2015160864A1 (en) 2014-04-14 2015-10-22 Sri International Portable nucleic acid analysis system and high-performance microfluidic electroactive polymer actuators
EP3594360B1 (en) 2014-04-24 2021-06-23 Lucira Health, Inc. Colorimetric detection of nucleic acid amplification
EP3160654A4 (en) 2014-06-27 2017-11-15 The Regents of The University of California Pcr-activated sorting (pas)
WO2016004539A1 (en) 2014-07-11 2016-01-14 Advanced Theranostics Inc. Point of care polymerase chain reaction device for disease detection
WO2016040523A1 (en) 2014-09-12 2016-03-17 Click Diagnostics, Inc. Multiplex optical detection
USD776290S1 (en) 2014-12-31 2017-01-10 W.H.P.M. Bioresearch And Technology Fecal occult blood detector
WO2016109691A1 (en) 2014-12-31 2016-07-07 Boris Andreyev Devices and methods for molecular diagnostic testing
EP3248018B1 (en) 2015-01-22 2020-01-08 Becton, Dickinson and Company Devices and systems for molecular barcoding of nucleic acid targets in single cells
KR102614191B1 (ko) 2015-04-24 2023-12-18 메사 바이오테크, 인크. 유체 테스트 카세트
GB201510723D0 (en) 2015-06-18 2015-08-05 Alere Switzerland Gmbh High throughput isothermal nucleic acid amplification
CN108136391B (zh) 2015-07-17 2021-01-26 克忧健康公司 用于增强检测和分析物定量的系统及方法
US10040069B2 (en) 2015-07-23 2018-08-07 General Electric Company Amplification and detection of nucleic acids
CA2992831A1 (en) 2015-07-24 2017-02-02 Cepheid Molecular diagnostic assay system
GB201519565D0 (en) 2015-11-05 2015-12-23 Alere San Diego Inc Sample preparation device
IL242807A0 (en) 2015-11-26 2016-04-21 Novamed Ltd Test facility
WO2017185067A1 (en) 2016-04-22 2017-10-26 Click Diagnostics, Inc. Printed circuit board heater for an amplification module
WO2017197040A1 (en) 2016-05-11 2017-11-16 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
MX2018015889A (es) 2016-06-29 2019-05-27 Click Diagnostics Inc Dispositivos y metodos para la deteccion de moleculas usando una celda de flujo.
CA3029682A1 (en) 2016-06-30 2018-01-04 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
WO2019094784A1 (en) 2017-11-09 2019-05-16 Click Diagnostics, Inc. Portable molecular diagnostic device and methods for the detection of target viruses
AU2019337088A1 (en) 2018-09-03 2021-05-06 Visby Medical, Inc. Devices and methods for antibiotic susceptibility testing

Also Published As

Publication number Publication date
US9623415B2 (en) 2017-04-18
JP2018505660A (ja) 2018-03-01
EP3240906A4 (en) 2018-09-05
US10279346B2 (en) 2019-05-07
CN107429281A (zh) 2017-12-01
US20210331159A9 (en) 2021-10-28
US20160186240A1 (en) 2016-06-30
AU2020217462B2 (en) 2022-08-11
US20210354131A9 (en) 2021-11-18
MX2017008618A (es) 2018-03-23
US10525469B2 (en) 2020-01-07
CA2972587A1 (en) 2016-07-07
US20190193077A1 (en) 2019-06-27
AU2015373998A1 (en) 2017-06-29
EP3240906B1 (en) 2021-08-25
US20170203297A1 (en) 2017-07-20
CN114958990A (zh) 2022-08-30
US20200406256A1 (en) 2020-12-31
CN107429281B (zh) 2022-05-27
ES2898103T3 (es) 2022-03-03
WO2016109691A1 (en) 2016-07-07
AU2020217462A1 (en) 2020-09-03
US11273443B2 (en) 2022-03-15
US20170259263A1 (en) 2017-09-14
US20180071734A1 (en) 2018-03-15
US20220055032A1 (en) 2022-02-24
US20190030532A1 (en) 2019-01-31
JP6778194B2 (ja) 2020-10-28
US20180117590A1 (en) 2018-05-03
JP2020188804A (ja) 2020-11-26
US20210354132A9 (en) 2021-11-18
EP4029606A1 (en) 2022-07-20
US10112196B2 (en) 2018-10-30
AU2020217462C1 (en) 2023-02-16
EP3240906A1 (en) 2017-11-08
US20190022643A1 (en) 2019-01-24
US11167285B2 (en) 2021-11-09
US10124334B2 (en) 2018-11-13
US10456783B2 (en) 2019-10-29
US20210039097A1 (en) 2021-02-11
HK1246826A1 (zh) 2018-09-14
US20190232283A1 (en) 2019-08-01
US10112197B2 (en) 2018-10-30
US10052629B2 (en) 2018-08-21

Similar Documents

Publication Publication Date Title
MX2021001972A (es) Dispositivos y metodos para prueba de diagnostico molecular.
MX2019003273A (es) Metodos y composiciones para detectar analitos.
PH12018500302A1 (en) Bio/chemical assay devices and methods for simplified steps, small samples, accelerated speed, and ease-of-use
PH12018500558B1 (en) Device and system for analyzing a sample, particularly blood, as well as methods of using the same
MX2018010575A (es) Amplificación automatizada por recombinasa-polimerasa anidada.
NZ728582A (en) Instrument for analyzing biological samples and reagents
MX2017012742A (es) Dispositivos y metodos para el analisis de muestras.
MX2020002799A (es) Dispositivo de ensayo biologico multiplexado con lectura electronica.
MX2018015704A (es) Control de fluidos.
MX2017005159A (es) Composiciones y metodos para detectar un virus de rna.
CL2016001867A1 (es) Sistema y dispositivo para la generación de alto rendimiento de gotitas y métodos de uso combinatorios.
BR112016027475A2 (pt) kit, dispositivo e método para a detecção de câncer pancreático
CL2022000350A1 (es) Sistema de diagnóstico
MX2017015758A (es) Componente de dispositivo, dispositivo, y metodo para purificar y ensayar biomoleculas de muestras biologicas.
WO2015187849A3 (en) Sample collection and analysis devices
MX2019003927A (es) Sistema de analisis y metodo para analizar una muestra.
EP3654036A3 (en) Stomach cancer biomarker and detection method
EA201791300A1 (ru) Флюидные системы, содержащие канал инкубации, включающие в себя флюидные системы, образованные литьевым формованием
MX2017001405A (es) Deteccion de acidos nucleicos diana mediante el uso de hibridacion.
MX2015014485A (es) Dispositivo de transferencia de muestreo de fluidos biologicos y sistema de separacion y analisis de fluidos biologicos.
MX2015001961A (es) Metodos y sistemas para ensayos.
BR112017008931A2 (pt) dispositivo microfluídico para detecção de gene-alvo, método para fabricação do mesmo e método para detecção com o uso do mesmo
MX2016009484A (es) Centrifuga compacta de alta velocidad para utilizarse con pequeños volumenes de muestra.
GB2545850A (en) System and method using a combined modality optical probe
FI20175460L (fi) Ionisaatiolaite