HK1246826A1 - 用於分子診斷測試的裝置和方法 - Google Patents

用於分子診斷測試的裝置和方法

Info

Publication number
HK1246826A1
HK1246826A1 HK18105885.7A HK18105885A HK1246826A1 HK 1246826 A1 HK1246826 A1 HK 1246826A1 HK 18105885 A HK18105885 A HK 18105885A HK 1246826 A1 HK1246826 A1 HK 1246826A1
Authority
HK
Hong Kong
Prior art keywords
methods
devices
diagnostic testing
molecular diagnostic
molecular
Prior art date
Application number
HK18105885.7A
Other languages
English (en)
Inventor
Boris Andreyev
Brian Ciopyk
La Zerda Adam De
Keith Moravick
David Swenson
Gregory Loney
Jesus Ching
Colin Kelly
Victor Briones
Steve Chu
Helen Huang
Original Assignee
Visby Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visby Medical Inc filed Critical Visby Medical Inc
Publication of HK1246826A1 publication Critical patent/HK1246826A1/zh

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5029Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures using swabs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/028Modular arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0684Venting, avoiding backpressure, avoid gas bubbles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0689Sealing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0654Lenses; Optical fibres
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0672Integrated piercing tool
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867Multiple inlets and one sample wells, e.g. mixing, dilution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883Serpentine channels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1838Means for temperature control using fluid heat transfer medium
    • B01L2300/1844Means for temperature control using fluid heat transfer medium using fans
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0605Valves, specific forms thereof check valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0605Valves, specific forms thereof check valves
    • B01L2400/0611Valves, specific forms thereof check valves duck bill valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0644Valves, specific forms thereof with moving parts rotary valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • B01L3/527Containers specially adapted for storing or dispensing a reagent for a plurality of reagents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
HK18105885.7A 2014-12-31 2018-05-07 用於分子診斷測試的裝置和方法 HK1246826A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462098769P 2014-12-31 2014-12-31
US201562213291P 2015-09-02 2015-09-02
PCT/US2015/068101 WO2016109691A1 (en) 2014-12-31 2015-12-30 Devices and methods for molecular diagnostic testing

Publications (1)

Publication Number Publication Date
HK1246826A1 true HK1246826A1 (zh) 2018-09-14

Family

ID=56163504

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105885.7A HK1246826A1 (zh) 2014-12-31 2018-05-07 用於分子診斷測試的裝置和方法

Country Status (10)

Country Link
US (12) US9623415B2 (zh)
EP (2) EP4029606A1 (zh)
JP (2) JP6778194B2 (zh)
CN (2) CN114958990A (zh)
AU (2) AU2015373998A1 (zh)
CA (1) CA2972587A1 (zh)
ES (1) ES2898103T3 (zh)
HK (1) HK1246826A1 (zh)
MX (2) MX2017008618A (zh)
WO (1) WO2016109691A1 (zh)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015138343A1 (en) 2014-03-10 2015-09-17 Click Diagnostics, Inc. Cartridge-based thermocycler
MX2017008618A (es) 2014-12-31 2018-03-23 Click Diagnostics Inc Dispositivos y métodos para prueba de diagnóstico molecular.
USD775363S1 (en) 2015-07-24 2016-12-27 Cepheid Molecular diagnostic system
US9646468B2 (en) * 2015-08-14 2017-05-09 Molecular Devices, Llc Sample-processing system with status lights
WO2017185067A1 (en) 2016-04-22 2017-10-26 Click Diagnostics, Inc. Printed circuit board heater for an amplification module
WO2017197040A1 (en) 2016-05-11 2017-11-16 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
USD800331S1 (en) 2016-06-29 2017-10-17 Click Diagnostics, Inc. Molecular diagnostic device
EP3478857A1 (en) 2016-06-29 2019-05-08 Click Diagnostics, Inc. Devices and methods for the detection of molecules using a flow cell
USD800914S1 (en) 2016-06-30 2017-10-24 Click Diagnostics, Inc. Status indicator for molecular diagnostic device
WO2018005870A1 (en) * 2016-06-30 2018-01-04 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
JP2020515817A (ja) 2016-12-29 2020-05-28 アドール ダイアグノスティクス エス.アール.エル. 電気泳動用途のための電気泳動チップ
US11346850B2 (en) 2017-06-21 2022-05-31 Gyntools Ltd Assay system including assay apparatus and handheld single use assay devices for use therewith
WO2019032574A1 (en) * 2017-08-07 2019-02-14 Fluid Handling Llc BLOCKED FLOW WITH PULSED INJECTION TECHNIQUE FOR TOTAL ORGANIC CARBON ANALYZER (TOCA) USING HIGH TEMPERATURE COMBUSTION
TWI650545B (zh) * 2017-08-22 2019-02-11 研能科技股份有限公司 致動傳感模組
CN107653300A (zh) * 2017-11-02 2018-02-02 浙江大学 测定土壤样品dna提取率的方法
EP3707276A4 (en) * 2017-11-09 2022-02-23 Visby Medical, Inc. PORTABLE MOLECULAR DIAGNOSTIC DEVICE AND METHODS FOR DETECTING TARGET VIRUSES
WO2019113261A1 (en) * 2017-12-06 2019-06-13 Entopsis Llc Separation device, and method of use, to remove pcr inhibitors from whole blood and serum samples
CA3044782A1 (en) 2017-12-29 2019-06-29 Clear Labs, Inc. Automated priming and library loading device
CA3097960A1 (en) * 2018-04-06 2019-10-10 Redbud Labs, Inc. Magnetic-based actuation mechanisms for and methods of actuating magnetically responsive microposts in a reaction chamber
WO2020035767A1 (en) * 2018-08-13 2020-02-20 Beckman Coulter Inc. Laboratory instrument for testing patient sample
US20210299669A1 (en) * 2018-09-03 2021-09-30 Visby Medical, Inc. Devices and methods for antibiotic susceptibility testing
KR101996617B1 (ko) * 2018-10-11 2019-07-04 주식회사 엘지화학 일체형 카트리지
CN111218383A (zh) * 2018-11-26 2020-06-02 杭州比格飞序生物科技有限公司 一种核酸提取装置及其方法
US20210129153A1 (en) * 2018-11-30 2021-05-06 Illumina, Inc. Systems and methods for active warming of a cartridge
DE102018130834A1 (de) * 2018-12-04 2020-06-04 Endress+Hauser Conducta Gmbh+Co. Kg Durchströmbare Messstelle
KR20210104835A (ko) * 2018-12-19 2021-08-25 누클레인, 엘엘씨 분자 진단을 위한 장치 및 방법
CN113784791A (zh) * 2019-04-28 2021-12-10 维斯比医学公司 具有数字检测能力和无线连接性的分子诊断设备
IL267301A (en) 2019-06-12 2019-11-28 Gyntools Ltd A test device and hand-held sample collection tools for it
US11008627B2 (en) * 2019-08-15 2021-05-18 Talis Biomedical Corporation Diagnostic system
CN110743634B (zh) * 2019-09-20 2021-06-01 华南农业大学 一种微流控设备
EP4051902A1 (en) * 2019-10-29 2022-09-07 Quantum-Si Incorporated Peristaltic pumping of fluids for bioanalytical applications and associated methods, systems, and devices
EP4028745B1 (en) * 2019-10-30 2024-05-08 GynTools Ltd Assay system including assay apparatus and handheld single use assay devices for use therewith
US11352675B2 (en) * 2020-01-03 2022-06-07 Visby Medical, Inc. Devices and methods for antibiotic susceptability testing
US20230053732A1 (en) * 2020-03-16 2023-02-23 Siemens Healthcare Diagnostics Inc. Sample holders, pcr station assemblies, and methods of operating pcr testing system
CN111575152B (zh) * 2020-05-27 2023-09-08 合肥中科易康达生物医学有限公司 一种集成核酸提取扩增检测功能于一体的封闭式卡盒及检测方法
CN116157500A (zh) * 2020-07-08 2023-05-23 卢马克特公司 采样设备和系统
JP7334363B2 (ja) * 2020-09-29 2023-08-28 富士フイルム株式会社 検査容器、検査装置及び核酸検査方法
WO2022090880A1 (fr) 2020-10-26 2022-05-05 Thierry Navarro Dispositif d'amplification d'adn ou arn et procede
CN112958173B (zh) * 2021-03-04 2023-01-10 深圳市美好创亿医疗科技股份有限公司 一种微流控试剂盒
US11432538B1 (en) * 2021-05-05 2022-09-06 The Florida International University Board Of Trustees Blood-feeding systems and methods for hematophagous arthropods
TWI785636B (zh) 2021-06-07 2022-12-01 新加坡商克雷多生醫有限公司 檢測卡匣
KR102375252B1 (ko) * 2021-06-29 2022-03-18 에스디바이오센서 주식회사 외측 챔버와 비드 챔버가 결합된 이중 챔버 구조의 유전체 추출 장치
KR102362853B1 (ko) * 2021-08-13 2022-02-15 에스디바이오센서 주식회사 내측 챔버와 결합되는 안전 클립을 포함하는 유전체 추출 장치
US11919004B2 (en) * 2021-08-30 2024-03-05 Wisconsin Alumni Research Foundation One-step sample extraction cassette and method for point-of-care molecular testing
EP4147647A1 (en) * 2021-09-14 2023-03-15 Kures S.r.l. Urine analysis device
RU210215U1 (ru) * 2021-10-15 2022-04-01 Федеральное государственное бюджетное учреждение «Федеральный научно-клинический центр физико-химической медицины Федерального медико-биологического агентства» Анализатор для проведения изотермической амплификации нуклеиновых кислот
CN114164091A (zh) * 2021-12-07 2022-03-11 广东润鹏生物技术有限公司 分子诊断样本处理系统及控制方法
WO2023216184A1 (zh) * 2022-05-12 2023-11-16 广州国家实验室 一种核酸扩增用卡盒
WO2023244945A1 (en) * 2022-06-13 2023-12-21 University Of Washington Diagnostic system including a base and single-use fluidic disposables

Family Cites Families (301)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697227A (en) 1966-05-13 1972-10-10 Westinghouse Electric Corp Chemical constituent sampler
US4710355A (en) 1984-06-14 1987-12-01 Olympus Optical Co., Ltd. Reagent delivery device
US4889692A (en) 1984-11-05 1989-12-26 Holtzman Marc E Disposable sample preparation container
USRE33858E (en) 1985-01-25 1992-03-24 Mallinckrodt Sensor Systems Inc. Apparatus for measuring a chemical entity in a liquid
IE64511B1 (en) 1988-03-11 1995-08-09 Takeda Chemical Industries Ltd Automated synthesizing apparatus
US5229297A (en) 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
US6645758B1 (en) 1989-02-03 2003-11-11 Johnson & Johnson Clinical Diagnostics, Inc. Containment cuvette for PCR and method of use
US5270183A (en) 1991-02-08 1993-12-14 Beckman Research Institute Of The City Of Hope Device and method for the automated cycling of solutions between two or more temperatures
US5273905A (en) 1991-02-22 1993-12-28 Amoco Corporation Processing of slide mounted material
US7297313B1 (en) 1991-08-31 2007-11-20 The Regents Of The University Of California Microfabricated reactor, process for manufacturing the reactor, and method of amplification
US5498392A (en) 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5587128A (en) 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US5726026A (en) 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
DE69302692T2 (de) 1992-07-06 1996-10-02 Beckman Instruments Inc Flüssigkeitsversorgungssystem mit Mehrwegventil
US5503985A (en) 1993-02-18 1996-04-02 Cathey; Cheryl A. Disposable device for diagnostic assays
US5429807A (en) 1993-10-28 1995-07-04 Beckman Instruments, Inc. Method and apparatus for creating biopolymer arrays on a solid support surface
US5631165A (en) 1994-08-01 1997-05-20 Abbott Laboratories Method for performing automated hematology and cytometry analysis
DE69533159T2 (de) * 1994-11-14 2005-07-21 Trustees Of The University Of Pennsylvania Miniaturisierte probenvorbereitungsvorrichtungen sowie systeme zur feststellung und behandlung von analyten
US5633168A (en) 1995-06-07 1997-05-27 Glasscock; Larry M. Controlled dispersion flow analysis system
US20050100946A1 (en) 1995-06-29 2005-05-12 Affymetrix, Inc. Integrated nucleic acid diagnostic device and method for in-situ confocal microscopy
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US6153425A (en) 1995-07-13 2000-11-28 Xtrana, Inc. Self-contained device integrating nucleic acid extraction, amplification and detection
US5773234A (en) 1995-08-07 1998-06-30 Quidel Corporation Method and device for chlamydia detection
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
AU6720096A (en) 1995-08-09 1997-03-05 Quidel Corporation Test strip and method for one step lateral flow assay
US7244622B2 (en) 1996-04-03 2007-07-17 Applera Corporation Device and method for multiple analyte detection
CA2591550C (en) 1996-06-04 2009-04-28 University Of Utah Research Foundation Monitoring hybridization during pcr
US5800784A (en) 1996-07-09 1998-09-01 Horn; Marcus J. Chemical sample treatment system and cassette, and methods for effecting multistep treatment process
US5882903A (en) 1996-11-01 1999-03-16 Sarnoff Corporation Assay system and method for conducting assays
DE29623597U1 (de) 1996-11-08 1999-01-07 Eppendorf Geraetebau Netheler Temperierblock mit Temperiereinrichtungen
US5952664A (en) 1997-01-17 1999-09-14 Imaging Diagnostic Systems, Inc. Laser imaging apparatus using biomedical markers that bind to cancer cells
US6924153B1 (en) 1997-03-06 2005-08-02 Quidel Corporation Quantitative lateral flow assays and devices
US6126804A (en) 1997-09-23 2000-10-03 The Regents Of The University Of California Integrated polymerase chain reaction/electrophoresis instrument
JP4209589B2 (ja) 1997-12-24 2009-01-14 シーフィード 一体型流体操作カートリッジ
US6369893B1 (en) 1998-05-19 2002-04-09 Cepheid Multi-channel optical detection system
US6303081B1 (en) 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US6146591A (en) 1998-05-01 2000-11-14 Miller; C David Biochemical detection system for rapid determination of the presence of toxins, bacteria, and other substances
US5976470A (en) 1998-05-29 1999-11-02 Ontogen Corporation Sample wash station assembly
US7799521B2 (en) 1998-06-24 2010-09-21 Chen & Chen, Llc Thermal cycling
US6780617B2 (en) 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
US6313471B1 (en) 1998-08-18 2001-11-06 Molecular Devices Corporation Scanning fluorometer
US20010055799A1 (en) 1998-12-15 2001-12-27 David Baunoch Method and apparatus for automated reprocessing of tissue samples
US6261431B1 (en) 1998-12-28 2001-07-17 Affymetrix, Inc. Process for microfabrication of an integrated PCR-CE device and products produced by the same
US6235479B1 (en) * 1999-04-13 2001-05-22 Bio Merieux, Inc. Methods and devices for performing analysis of a nucleic acid sample
US20020177135A1 (en) * 1999-07-27 2002-11-28 Doung Hau H. Devices and methods for biochip multiplexing
EP1180135B1 (en) 1999-05-28 2005-08-17 Cepheid Apparatus and method for cell disruption
GB9922971D0 (en) 1999-09-29 1999-12-01 Secr Defence Reaction system
JP2001186881A (ja) 1999-10-22 2001-07-10 Ngk Insulators Ltd Dnaチップの製造方法
US6699713B2 (en) 2000-01-04 2004-03-02 The Regents Of The University Of California Polymerase chain reaction system
FR2812306B1 (fr) 2000-07-28 2005-01-14 Gabriel Festoc Systeme d'amplification en chaine par polymerse de sequences nucleiques cibles
US6374684B1 (en) 2000-08-25 2002-04-23 Cepheid Fluid control and processing system
US8048386B2 (en) 2002-02-25 2011-11-01 Cepheid Fluid processing and control
US6610499B1 (en) 2000-08-31 2003-08-26 The Regents Of The University Of California Capillary array and related methods
US6680617B2 (en) 2000-09-20 2004-01-20 Neocera, Inc. Apertured probes for localized measurements of a material's complex permittivity and fabrication method
US6911181B1 (en) 2000-10-03 2005-06-28 Isis Pharmaceuticals, Inc. Self-dispensing storage device
SE0004297D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device for thermal cycling
US6780380B2 (en) 2001-01-16 2004-08-24 Triangle Biomedical Sciences, Inc. Tissue processor
AU2002306486A1 (en) 2001-02-09 2002-08-28 Microchem Solutions Method and apparatus for sample injection in microfabricated devices
US6426215B1 (en) 2001-04-06 2002-07-30 Pe Corporation (Ny) PCR plate cover and maintaining device
US6905885B2 (en) 2001-06-12 2005-06-14 The Regents Of The University Of California Portable pathogen detection system
US20040018502A1 (en) 2001-06-14 2004-01-29 Yoshihiko Makino Method for analyzing a target nucleic acid fragment and a kit for analyzing a target nucleic acid fragment
JP3705499B2 (ja) * 2001-06-14 2005-10-12 富士写真フイルム株式会社 ターゲット核酸断片の分析方法及びターゲット核酸断片の分析キット
US6514750B2 (en) 2001-07-03 2003-02-04 Pe Corporation (Ny) PCR sample handling device
EP1415113B1 (en) 2001-07-16 2011-08-31 Idaho Technology, Inc. Thermal cycling system and method of use
US7280207B2 (en) 2001-07-25 2007-10-09 Applera Corporation Time-delay integration in a flow cytometry system
US7265833B2 (en) 2001-07-25 2007-09-04 Applera Corporation Electrophoretic system with multi-notch filter and laser excitation source
AUPR707101A0 (en) 2001-08-16 2001-09-06 Corbett Research Pty Ltd Continuous flow thermal device
US6855561B2 (en) 2001-09-10 2005-02-15 Quidel Corporation Method for adding an apparent non-signal line to a lateral flow assay
US7879293B2 (en) 2001-09-28 2011-02-01 Orasure Technologies, Inc. Sample collector and test device
US7371346B2 (en) 2001-10-01 2008-05-13 Leica Biosystems Melbourne Pty Ltd Histological tissue specimen treatment
US7459302B2 (en) 2001-10-02 2008-12-02 Stratagene California Side-wall heater for thermocycler device
US7691333B2 (en) 2001-11-30 2010-04-06 Fluidigm Corporation Microfluidic device and methods of using same
US20030116552A1 (en) 2001-12-20 2003-06-26 Stmicroelectronics Inc. Heating element for microfluidic and micromechanical applications
US6813568B2 (en) 2002-01-09 2004-11-02 Memorial Sloan-Kettering Cancer Center System and process for microfluidics-based automated chemistry
US6677151B2 (en) 2002-01-30 2004-01-13 Applera Corporation Device and method for thermal cycling
US8030000B2 (en) 2002-02-21 2011-10-04 Alere San Diego, Inc. Recombinase polymerase amplification
JP3892743B2 (ja) 2002-03-01 2007-03-14 日本碍子株式会社 反応セルおよびその使用方法
US7179639B2 (en) 2002-03-05 2007-02-20 Raveendran Pottathil Thermal strip thermocycler
EP1376131A1 (en) 2002-06-27 2004-01-02 Inverness Medical Switzerland GmbH Assay device for liquid sample
JP4013671B2 (ja) 2002-07-05 2007-11-28 松下電器産業株式会社 ポリメラーゼ連鎖反応容器及びその製造方法
US7452712B2 (en) 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
US7449302B2 (en) 2002-10-02 2008-11-11 The University Of Bristol, University Walk Therapeutic peptides
US7291459B2 (en) 2002-12-10 2007-11-06 University Of Alabama At Huntsville Nucleic acid detector and method of detecting targets within a sample
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
EP1592505A2 (en) 2003-01-21 2005-11-09 Micronics, Inc. Method and system for microfluidic manipulation, amplification and analysis of fluids, for example, bacteria assays and antiglobulin testing
US6901217B2 (en) 2003-02-28 2005-05-31 Motorolr, Inc. Conduits integrated in circuit board and method of manufacture
US6781056B1 (en) 2003-02-28 2004-08-24 Motorola, Inc. Heater for temperature control integrated in circuit board and method of manufacture
US7041481B2 (en) 2003-03-14 2006-05-09 The Regents Of The University Of California Chemical amplification based on fluid partitioning
US7151270B2 (en) 2003-05-02 2006-12-19 Leica Microsystems Cms Gmbh Method for classifying object image regions of an object to be detected using a scanning microscope
US7148043B2 (en) 2003-05-08 2006-12-12 Bio-Rad Laboratories, Inc. Systems and methods for fluorescence detection with a movable detection module
US7648835B2 (en) 2003-06-06 2010-01-19 Micronics, Inc. System and method for heating, cooling and heat cycling on microfluidic device
CA2956645A1 (en) 2003-07-12 2005-03-31 David A. Goldberg Sensitive and rapid biodetection
US7517495B2 (en) 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
WO2005028635A2 (en) * 2003-09-19 2005-03-31 Microfluidic Systems Inc. Microfluidic differential extraction cartridge
US7378285B2 (en) 2003-09-22 2008-05-27 Paul Lambotte Devices for the detection of multiple analytes in a sample
NZ547174A (en) 2003-11-14 2009-09-25 Inverness Medical Switzerland Rapid sample collection and analysis device and methods of use
DE212004000058U1 (de) 2003-11-14 2006-09-28 Oakville Hong Kong Co., Ltd. Probensammelbehälter mit integriertem aktivierbaren Probenanalysesystem
NZ547175A (en) 2003-11-14 2009-11-27 Oakville Hong Kong Co Ltd Sample collection cup with integrated sample analysis system
US7767439B2 (en) 2003-12-10 2010-08-03 Samsung Electronics Co., Ltd. Real-time PCR monitoring apparatus and method
KR100750586B1 (ko) 2003-12-26 2007-08-20 한국전자통신연구원 미소유체 가열 시스템
US8765454B2 (en) 2004-02-18 2014-07-01 Xiaochuan Zhou Fluidic devices and methods for multiplex chemical and biochemical reactions
WO2005083390A1 (en) 2004-02-20 2005-09-09 Research Foundation Of The State University Of New York Method and device for manipulating liquids in microfluidic systems
KR100552706B1 (ko) * 2004-03-12 2006-02-20 삼성전자주식회사 핵산 증폭 방법 및 장치
WO2005095967A1 (en) 2004-03-23 2005-10-13 Quidel Corporation Hybrid phase lateral flow assay
US20050227275A1 (en) 2004-04-07 2005-10-13 Access Bio, Inc. Nucleic acid detection system
CA2502549C (en) 2004-04-23 2016-02-16 Becton, Dickinson And Company Use of an extraction control in a method of extracting nucleic acids
EP1598429A1 (en) 2004-05-19 2005-11-23 Amplion Ltd. Detection of amplicon contamination during PCR exhibiting two different annealing temperatures
US7871143B2 (en) 2004-06-30 2011-01-18 Lexmark International, Inc. Ground structure for temperature-sensing resistor noise reduction
US7662562B2 (en) 2004-08-10 2010-02-16 Becton, Dickinson And Company Method for rapid identification of microorganisms
US7192721B1 (en) 2004-08-26 2007-03-20 Chembio Diagnostic Systems, Inc. Universal rapid test and method for detection of tuberculosis in multiple host species
US7592139B2 (en) 2004-09-24 2009-09-22 Sandia National Laboratories High temperature flow-through device for rapid solubilization and analysis
US9132398B2 (en) 2007-10-12 2015-09-15 Rheonix, Inc. Integrated microfluidic device and methods
BRPI0517105B1 (pt) 2004-10-18 2015-06-23 Univ Brandeis Método para análise de pelo menos um produto de amplificação fita simples de um processo de amplificação de ácido nucléico não-simétrico
EP1805318B1 (en) 2004-10-27 2014-09-03 Cepheid Closed-system multi-stage nucleic acid amplification reactions
US8883487B2 (en) 2004-12-23 2014-11-11 Abbott Point Of Care Inc. Molecular diagnostics system and methods
KR100601982B1 (ko) 2005-01-20 2006-07-18 삼성전자주식회사 흡열반응을 통한 가열-냉각 과정에 의한 세포 용해 방법
DK1859330T3 (da) 2005-01-28 2012-10-15 Univ Duke Apparater og fremgangsmåder til håndtering af små dråber på et trykt kredsløbskort
WO2006094149A2 (en) 2005-03-01 2006-09-08 Exact Sciences Corporation Methods and compositions for detecting adenoma
US7189522B2 (en) 2005-03-11 2007-03-13 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
US20060246493A1 (en) * 2005-04-04 2006-11-02 Caliper Life Sciences, Inc. Method and apparatus for use in temperature controlled processing of microfluidic samples
US20070026391A1 (en) 2005-04-11 2007-02-01 Ghc Technologies, Inc. Methods and compositions for identifying chemical or biological agents using multiplexed labeling and colocalization detection
US7235216B2 (en) 2005-05-01 2007-06-26 Iba Molecular North America, Inc. Apparatus and method for producing radiopharmaceuticals
KR100695148B1 (ko) 2005-05-02 2007-03-14 삼성전자주식회사 중합효소 연쇄반응용 모듈 및 이를 채용한 다중 중합효소 연쇄반응 장치
WO2006130299A2 (en) 2005-05-03 2006-12-07 Micronics, Inc. Microfluidic laminar flow detection strip
EP1920070B1 (en) 2005-05-09 2019-08-07 BioFire Diagnostics, LLC Self-contained biological analysis
KR101431775B1 (ko) 2005-05-11 2014-08-20 듀크 유니버서티 복수의 온도에서 생화학적 또는 화학적 반응을 수행하기위한 방법 및 장치
WO2006122310A2 (en) * 2005-05-11 2006-11-16 The Trustess Of The University Of Pennsylvania System for testing
AU2006309284B2 (en) * 2005-05-31 2012-08-02 Board Of Regents, The University Of Texas System Methods and compositions related to determination and use of white blood cell counts
EP2508867A1 (en) 2005-06-24 2012-10-10 Board Of Regents, The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
TW200714898A (en) 2005-08-02 2007-04-16 3M Innovative Properties Co Apparatus and method for detecting an analyte
US7618588B2 (en) 2005-08-10 2009-11-17 Microfluidic Systems, Inc. Disposable integrated heater and tube assembly for thermally-driven chemical reactions
US7569382B2 (en) 2005-10-05 2009-08-04 Instantlabs Medical Diagnostic Corp. Disposable reactor module and detection system
US8916375B2 (en) 2005-10-12 2014-12-23 University Of Virginia Patent Foundation Integrated microfluidic analysis systems
US7754148B2 (en) 2006-12-27 2010-07-13 Progentech Limited Instrument for cassette for sample preparation
CN100478671C (zh) 2005-10-25 2009-04-15 艾康生物技术(杭州)有限公司 用于液体样本的检测装置和方法
US7858396B2 (en) 2005-10-31 2010-12-28 Orasure Technologies, Inc. Lateral flow assay device with multiple equidistant capture zones
US8871155B2 (en) 2005-11-30 2014-10-28 Alere Switzerland Gmbh Devices for detecting analytes in fluid sample
WO2007078833A2 (en) 2005-12-16 2007-07-12 The Curators Of The University Of Missouri Reusable pcr amplification system and method
US7959877B2 (en) 2005-12-22 2011-06-14 Chembio Diagnostic Systems, Inc. Immunoassay apparatus and kit
US7377291B2 (en) 2005-12-28 2008-05-27 Serveron Corporation Multiport rotary valve
JP5178528B2 (ja) * 2005-12-29 2013-04-10 アボット ポイント オブ ケア インコーポレイテッド 分子診断用増幅システムおよび方法
US7871568B2 (en) 2006-01-23 2011-01-18 Quidel Corporation Rapid test apparatus
US7794656B2 (en) 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
US20080050735A1 (en) 2006-02-01 2008-02-28 Elena Pushnova Nucleic acid testing method for point-of-care diagnostics and genetic self-monitoring
GB0603965D0 (en) 2006-02-28 2006-04-05 Centeo Biosciences Ltd Incubator apparatus and method
ES2393758T3 (es) 2006-03-15 2012-12-27 Micronics, Inc. Ensayos integrados de ácidos nucleicos
US8088616B2 (en) 2006-03-24 2012-01-03 Handylab, Inc. Heater unit for microfluidic diagnostic system
JP5415253B2 (ja) * 2006-03-24 2014-02-12 ハンディラブ・インコーポレーテッド 微小流体サンプルを処理するための一体化システム及びその使用方法
WO2008036121A2 (en) 2006-04-25 2008-03-27 University Of South Florida Portable reactor for real-time nucleic acid amplification and detection
US8900828B2 (en) 2006-05-01 2014-12-02 Cepheid Methods and apparatus for sequential amplification reactions
US8232091B2 (en) 2006-05-17 2012-07-31 California Institute Of Technology Thermal cycling system
US8137626B2 (en) 2006-05-19 2012-03-20 California Institute Of Technology Fluorescence detector, filter device and related methods
WO2007149791A2 (en) 2006-06-15 2007-12-27 Stratagene System for isolating biomolecules from a sample
US20080153078A1 (en) 2006-06-15 2008-06-26 Braman Jeffrey C System for isolating biomolecules from a sample
AU2007265628B2 (en) 2006-06-23 2012-12-06 Perkinelmer Health Sciences, Inc. Methods and devices for microfluidic point-of-care immunoassays
US7629124B2 (en) 2006-06-30 2009-12-08 Canon U.S. Life Sciences, Inc. Real-time PCR in micro-channels
US8187557B2 (en) 2006-07-13 2012-05-29 Cepheid Reagent reservoir system for analytical instruments
EP1878802A1 (en) 2006-07-14 2008-01-16 Roche Diagnostics GmbH Disposable device for analysing a liquid sample containing a nucleic acid with a nucleic acid amplification apparatus
US8980561B1 (en) 2006-08-22 2015-03-17 Los Alamos National Security, Llc. Nucleic acid detection system and method for detecting influenza
WO2008105814A2 (en) 2006-08-22 2008-09-04 Los Alamos National Security, Llc Miniturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids
GB0617035D0 (en) 2006-08-30 2006-10-11 Inverness Medical Switzerland Fluidic indicator device
GB0718250D0 (en) 2007-08-29 2007-10-31 B G Res Ltd Improvements in and relating to reaction apparatus
US7985716B2 (en) 2006-09-22 2011-07-26 Uchicago Argonne, Llc Nucleic acid sample purification and enrichment with a thermo-affinity microfluidic sub-circuit
WO2008147382A1 (en) 2006-09-27 2008-12-04 Micronics, Inc. Integrated microfluidic assay devices and methods
WO2008045288A2 (en) 2006-10-06 2008-04-17 Vandalia Research, Inc. Method for a continuous rapid thermo cycle system
US8263392B2 (en) 2006-11-14 2012-09-11 University Of Utah Research Foundation Methods and compositions related to continuous flow thermal gradient PCR
US8709787B2 (en) 2006-11-14 2014-04-29 Handylab, Inc. Microfluidic cartridge and method of using same
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
US8735103B2 (en) 2006-12-05 2014-05-27 Electronics And Telecommunications Research Institute Natural convection-driven PCR apparatus and method using disposable polymer chip
GB0625309D0 (en) 2006-12-19 2007-01-24 Inverness Medical Switzerland Device
US8338166B2 (en) 2007-01-04 2012-12-25 Lawrence Livermore National Security, Llc Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
WO2008091572A1 (en) 2007-01-22 2008-07-31 Orasure Technologies, Inc. Container and method for supporting home testing and diagnosis of infectious diseases
US20110039303A1 (en) 2007-02-05 2011-02-17 Stevan Bogdan Jovanovich Microfluidic and nanofluidic devices, systems, and applications
US8298763B2 (en) 2007-03-02 2012-10-30 Lawrence Livermore National Security, Llc Automated high-throughput flow-through real-time diagnostic system
EP3677905A1 (en) 2007-04-04 2020-07-08 ANDE Corporation Integrated nucleic acid analysis
US8580575B2 (en) 2007-04-13 2013-11-12 Shimadzu Corporation Reactor plate and reaction processing method
JP4992524B2 (ja) 2007-04-13 2012-08-08 株式会社島津製作所 反応容器プレート及び反応処理方法
JP2010525322A (ja) 2007-04-20 2010-07-22 クイデル コーポレイション 統合乾燥剤付きの分析装置
KR101228308B1 (ko) 2007-05-23 2013-01-31 삼성전자주식회사 미세유동 칩을 이용한 디스크형 미세유동장치 및 생체물질마이크로어레이 칩을 이용한 디스크형 미세유동장치
GB0710957D0 (en) 2007-06-07 2007-07-18 Norchip As A device for carrying out cell lysis and nucleic acid extraction
WO2009002447A1 (en) 2007-06-21 2008-12-31 Gen-Probe Incorporated Instrument and receptacles for use in performing processes
JP5045268B2 (ja) 2007-06-28 2012-10-10 ソニー株式会社 反応処理装置
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8678239B2 (en) 2007-07-13 2014-03-25 The Coca-Cola Company Clean in place system for beverage dispensers
US8076129B2 (en) 2007-07-26 2011-12-13 Shimadzu Corporation Reactor plate and reaction processing method
JP5852781B2 (ja) 2007-07-31 2016-02-03 マイクロニクス, インコーポレイテッド 衛生的スワブ採取システム、マイクロ流体アッセイデバイスおよび診断アッセイのための方法
US7955840B2 (en) 2007-08-23 2011-06-07 Akonni Biosystems Thermal cycler for PCR including temperature control bladder
CL2008003007A1 (es) 2007-10-12 2009-10-02 Bigtec Private Ltd Un micro chip con capas de ceramicas de coccion conjunta a baja temperatura (ltcc) formando una camara de reaccion, anillos conductores que rodean a la camara de reaccion y un calentador que suministra calor a los anillos, el metodo de fabricacion del micro chip y un micro dispositivo de reaccion en cadena de polimerasa (pcr).
US8222048B2 (en) 2007-11-05 2012-07-17 Abbott Laboratories Automated analyzer for clinical laboratory
US8075854B2 (en) 2007-11-08 2011-12-13 The Ohio State University Research Foundation Bioprocessing Innovative Company Microfluidic chips for rapid multiplex ELISA
DE102007062441A1 (de) 2007-12-20 2009-06-25 Aj Innuscreen Gmbh Mobiles Schnelltestsystem für die Nukleinsäureanalytik
WO2009117167A1 (en) 2008-01-02 2009-09-24 Blood Cell Storage, Inc. Devices and processes for nucleic acid extraction
CN101990516B (zh) * 2008-01-22 2015-09-09 英特基因有限公司 多用试样准备系统及其在集成分析系统中的使用
KR101465701B1 (ko) 2008-01-22 2014-11-28 삼성전자 주식회사 핵산 증폭 장치
EP2238459B1 (en) 2008-01-23 2019-05-08 Roche Diagnostics GmbH Integrated instrument performing synthesis and amplification
US20090186344A1 (en) 2008-01-23 2009-07-23 Caliper Life Sciences, Inc. Devices and methods for detecting and quantitating nucleic acids using size separation of amplicons
US20090215050A1 (en) 2008-02-22 2009-08-27 Robert Delmar Jenison Systems and methods for point-of-care amplification and detection of polynucleotides
WO2009137059A1 (en) 2008-05-05 2009-11-12 Los Alamos National Security, Llc Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control
US20110160090A1 (en) 2008-05-05 2011-06-30 Los Alamos National Laboratory Nanocrystal-Based Lateral Flow Microarrays and Low-Voltage Signal Detection Systems
CA2731723A1 (en) 2008-07-23 2010-01-28 Ancora Pharmaceuticals Inc. Automated oligosaccharide synthesizer
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
EP2331259B1 (en) 2008-09-23 2013-09-11 Koninklijke Philips Electronics N.V. Thermocycling process
US9156010B2 (en) 2008-09-23 2015-10-13 Bio-Rad Laboratories, Inc. Droplet-based assay system
EP2172703A1 (en) 2008-10-03 2010-04-07 J & H ApS Emergency light device for marine environments
US8058005B2 (en) 2008-10-23 2011-11-15 Honeywell International Inc. Method for single nucleotide polymorphism and mutation detection using real time polymerase chain reaction microarray
WO2010054004A2 (en) 2008-11-04 2010-05-14 Blood Cell Storage, Inc. Nucleic acid extraction on curved glass surfaces
US8110148B2 (en) 2008-11-06 2012-02-07 Siemens Medical Solutions Usa, Inc. Apparatus and method using rotary flow distribution mechanisms
WO2010059051A2 (en) * 2008-11-20 2010-05-27 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Rapid fret based pathogen diagnosis
CN101556277B (zh) 2009-01-05 2012-12-26 艾博生物医药(杭州)有限公司 检测装置
US8058630B2 (en) 2009-01-16 2011-11-15 Fluidigm Corporation Microfluidic devices and methods
WO2010088514A1 (en) 2009-01-30 2010-08-05 Micronics, Inc. Portable high gain fluorescence detection system
EP2406614A1 (en) 2009-03-10 2012-01-18 Agency For Science, Technology And Research Apparatus for processing a biological and/or chemical sample
AU2010229490B2 (en) 2009-03-24 2015-02-12 University Of Chicago Slip chip device and methods
US20100291536A1 (en) 2009-05-14 2010-11-18 Streck, Inc. Sample processing cassette, system, and method
WO2010141940A1 (en) 2009-06-05 2010-12-09 Alere San Diego, Inc. Recombinase polymerase amplification reagents and kits
BRPI1010169A2 (pt) 2009-06-05 2016-03-29 Integenx Inc sistema que se ajusta dentro de um invólucro de não mais que 10 pés3, cartucho, artigo em forma legível por computador, método, sistema configurado para realizar um método, sistema óptico, instrumento e dispositivo.
US9625454B2 (en) 2009-09-04 2017-04-18 The Research Foundation For The State University Of New York Rapid and continuous analyte processing in droplet microfluidic devices
US8008080B2 (en) 2009-09-23 2011-08-30 Ecolab Usa Inc. Valve analytical system
EE201000013A (et) 2010-01-29 2011-10-17 Selfdiagnostics O� Meetod ja kiirtesti seade sihtm„rk-molekuli proovimaterjalist detekteerimiseks
CA2977845C (en) 2010-02-23 2020-08-04 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
US8791675B2 (en) * 2010-03-22 2014-07-29 Pine Valley Investments, Inc. Mobile wireless communications device including removable electrical power supply module and related methods
US20110244466A1 (en) * 2010-04-02 2011-10-06 Robert Juncosa Nucleic acid testing device and method
EP2556173B1 (en) 2010-04-09 2021-05-26 Life Technologies Corporation Improved thermal uniformity for thermal cycler instrumentation using dynamic control
US8435737B2 (en) * 2010-06-02 2013-05-07 Cal Poly Corporation Primers for the rapid and specific detection of propane-oxidizing and butane-oxidizing microorganisms and methods of using same
US20110308945A1 (en) 2010-06-17 2011-12-22 Geneasys Pty Ltd Genetic analysis loc device with thick electrodes for electrochemiluminescent detection of target sequences
KR20120020528A (ko) 2010-08-30 2012-03-08 삼성전자주식회사 중합효소 연쇄반응 장치
WO2012033765A1 (en) 2010-09-07 2012-03-15 The Arizona Board Of Regents On Behalf Of The University Of Arizona Microdroplet-manipulation systems and methods for automated execution of molecular biological protocols
CN103118784A (zh) 2010-09-22 2013-05-22 康宁股份有限公司 微孔微流体装置
US8795592B2 (en) 2010-09-23 2014-08-05 Analogic Corporation Sample thermal cycling
US8945843B2 (en) 2010-12-09 2015-02-03 Analogic Corporation Thermocooler with thermal breaks that thermally isolate a thermocycling region from at least one guard heat region
EP2668501B1 (en) 2011-01-27 2019-06-12 Invisible Sentinel, Inc. Analyte detection devices, multiplex and tabletop devices for detection of analytes, and uses thereof
US8603835B2 (en) 2011-02-10 2013-12-10 Chembio Diagnostic Systems, Inc. Reduced step dual path immunoassay device and method
WO2012121225A1 (ja) * 2011-03-04 2012-09-13 株式会社カネカ 核酸の検出方法及びその方法に用いるデバイス、キット
US20120264202A1 (en) 2011-03-23 2012-10-18 Walker Christopher I System for performing polymerase chain reaction nucleic acid amplification
US9469871B2 (en) 2011-04-14 2016-10-18 Corporos Inc. Methods and apparatus for point-of-care nucleic acid amplification and detection
US8911941B2 (en) 2011-04-14 2014-12-16 Kenneth J. Michlitsch Methods and apparatus for point-of-care nucleic acid amplification and detection
WO2012145725A2 (en) 2011-04-20 2012-10-26 Mesa Tech International, Inc. Oscillating amplification reaction for nucleic acids
WO2013040008A1 (en) 2011-09-12 2013-03-21 University Of Notre Dame Du Lac Systems and methods for bead-free detection of nucleotides
EP2705130B1 (en) 2011-05-04 2016-07-06 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
JP2012242118A (ja) 2011-05-16 2012-12-10 Canon Inc 流体デバイスを用いる熱処理装置、および流体の処理方法
US8629264B2 (en) 2011-05-19 2014-01-14 Blood Cell Storage, Inc. Gravity flow fluidic device for nucleic acid extraction
US8347490B1 (en) 2011-06-30 2013-01-08 Chipbond Technology Corporation Method for fabricating a carrier with a three dimensional inductor
US9435765B2 (en) * 2011-07-22 2016-09-06 Tecan Trading Ag Cartridge and system for manipulating samples in liquid droplets
US20150258273A1 (en) 2011-08-31 2015-09-17 Forrest W. Payne Electrochemically-Actuated Microfluidic Devices
US9352312B2 (en) * 2011-09-23 2016-05-31 Alere Switzerland Gmbh System and apparatus for reactions
US8894946B2 (en) 2011-10-21 2014-11-25 Integenx Inc. Sample preparation, processing and analysis systems
CN104040238B (zh) 2011-11-04 2017-06-27 汉迪拉布公司 多核苷酸样品制备装置
WO2013071258A1 (en) 2011-11-11 2013-05-16 Icubate, Inc. Systems and methods for performing amplicon rescue multiplex polymerase chain reaction (pcr)
EP2784513A4 (en) 2011-11-25 2015-07-15 Toppan Printing Co Ltd CHIP FOR SAMPLE ANALYSIS, SAMPLE ANALYSIS METHOD, AND GENE ANALYSIS METHOD
CN103184143A (zh) 2011-12-29 2013-07-03 三星电子株式会社 固体试剂溶解器件以及使用其溶解固体试剂的方法
WO2013112755A1 (en) 2012-01-24 2013-08-01 The Trustees Of Columbia University In The City Of New York Field optimized assay devices, methods, and systems
US9533308B2 (en) 2012-02-10 2017-01-03 California Institute Of Technology PC board-based polymerase chain reaction systems, methods and materials
US9322054B2 (en) * 2012-02-22 2016-04-26 Lockheed Martin Corporation Microfluidic cartridge
US9035204B2 (en) 2012-02-29 2015-05-19 Reliance Controls Corporation Switch assembly with sequentially actuated power and neutral switching
WO2013131057A1 (en) 2012-03-01 2013-09-06 Quidel Corporation System and apparatus for point-of-care diagnostics
US10273532B2 (en) 2012-03-09 2019-04-30 National Institute Of Advanced Industrial Science And Technology Nucleic acid amplification method
US9238833B2 (en) 2012-04-17 2016-01-19 California Institute Of Technology Thermally controlled chamber with optical access for high-performance PCR
US9150907B2 (en) 2012-04-27 2015-10-06 General Electric Company Microfluidic flow cell assemblies and method of use
US9044729B2 (en) 2012-07-27 2015-06-02 International Park Of Creativity Methods and devices for electromagnetic amplification of nucleic acids
WO2014025924A1 (en) 2012-08-07 2014-02-13 California Institute Of Technology Ultrafast thermal cycler
US9364833B2 (en) 2012-08-17 2016-06-14 Lexmark International, Inc. Micro-fluidic modules on a chip for diagnostic applications
EP3348990A1 (en) 2012-08-28 2018-07-18 Akonni Biosystems, Inc. Method and kit for purifying nucleic acids
US20140098252A1 (en) 2012-09-05 2014-04-10 Cepheid Universal Docking Bay and Data Door in a Fluidic Analysis System
EP2895852A4 (en) 2012-09-11 2016-05-25 Univ Cornell APPARATUS AND METHOD FOR MEASURING ON THE COLLECTION POINT OF A BIOMOLECULAR REACTION
WO2014047523A2 (en) 2012-09-21 2014-03-27 California Institute Of Technology Methods and devices for sample lysis
US20150290639A1 (en) 2012-12-03 2015-10-15 Vladimir Evtodienko Pressure assisted lateral flow diagnostic device
EP2935559B1 (en) * 2012-12-21 2020-09-16 PerkinElmer Health Sciences, Inc. Fluorescence detection system
WO2014112671A1 (ko) 2013-01-21 2014-07-24 나노바이오시스(주) 핵산 추출용 미세유동 칩, 이를 포함하는 핵산 추출 장치, 및 이를 이용하는 핵산 추출 방법
CN105164514A (zh) 2013-01-21 2015-12-16 康奈尔大学 基于智能手机的装置和用于获取可重复的定量比色测量的方法
US9995412B2 (en) 2013-03-01 2018-06-12 Wave 80 Biosciences, Inc. Long-throw microfluidic actuator
US9789483B2 (en) 2013-03-11 2017-10-17 Cue Inc. System for portable and easy-to-use detection of analytes with mobile computing device
US9623409B2 (en) 2013-03-11 2017-04-18 Cue Inc. Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes
US20140274770A1 (en) 2013-03-13 2014-09-18 Quidel Corporation Pcr assays and reagents for molecular detection of infectious agents
WO2014144548A2 (en) * 2013-03-15 2014-09-18 Nanobiosym, Inc. Systems and methods for mobile device analysis of nucleic acids and proteins
WO2014190258A1 (en) 2013-05-23 2014-11-27 The Regents Of The University Of California Proximal degas driven microfluidic actuation
WO2015019522A1 (ja) 2013-08-08 2015-02-12 パナソニック株式会社 核酸増幅デバイス、核酸増幅装置及び核酸増幅方法
WO2015103326A1 (en) 2013-12-31 2015-07-09 Canon U.S. Life Sciences, Inc. Field deployable small format fast first result microfluidic system
US20180135108A1 (en) 2014-01-20 2018-05-17 Board Of Trustees Of Michigan State University Method for detecting bacterial and fungal pathogens
WO2015138343A1 (en) 2014-03-10 2015-09-17 Click Diagnostics, Inc. Cartridge-based thermocycler
EP3698874A1 (en) 2014-03-11 2020-08-26 Illumina, Inc. Disposable, integrated microfluidic cartridge and methods of making the same
ES2891303T3 (es) 2014-04-14 2022-01-27 Stanford Res Inst Int Sistema portátil de análisis de ácidos nucleicos y actuadores de polímeros electroactivos microfluídicos de alto rendimiento
PT3594360T (pt) 2014-04-24 2021-08-19 Lucira Health Inc Deteção colorimétrica da amplificação do ácido nucleico
EP3160654A4 (en) 2014-06-27 2017-11-15 The Regents of The University of California Pcr-activated sorting (pas)
EP3167045A4 (en) 2014-07-11 2018-01-17 Advanced Theranostics Inc. Point of care polymerase chain reaction device for disease detection
US20170247745A1 (en) 2014-09-12 2017-08-31 Click Diagnostics, Inc. Multiplex optical detection
MX2017008618A (es) 2014-12-31 2018-03-23 Click Diagnostics Inc Dispositivos y métodos para prueba de diagnóstico molecular.
USD776290S1 (en) 2014-12-31 2017-01-10 W.H.P.M. Bioresearch And Technology Fecal occult blood detector
US20160289669A1 (en) 2015-01-22 2016-10-06 Becton, Dickinson And Company Devices and systems for molecular barcoding of nucleic acid targets in single cells
WO2016172724A1 (en) 2015-04-24 2016-10-27 Mesa Biotech, Inc. Fluidic test cassette
GB201510723D0 (en) 2015-06-18 2015-08-05 Alere Switzerland Gmbh High throughput isothermal nucleic acid amplification
AU2016296589B2 (en) 2015-07-17 2021-11-18 Cue Health Inc. Systems and methods for enhanced detection and quantification of analytes
US10040069B2 (en) 2015-07-23 2018-08-07 General Electric Company Amplification and detection of nucleic acids
WO2017019569A1 (en) 2015-07-24 2017-02-02 Cepheid Molecular diagnostic assay system
GB201519565D0 (en) 2015-11-05 2015-12-23 Alere San Diego Inc Sample preparation device
IL242807A0 (en) 2015-11-26 2016-04-21 Novamed Ltd Test facility
WO2017185067A1 (en) 2016-04-22 2017-10-26 Click Diagnostics, Inc. Printed circuit board heater for an amplification module
WO2017197040A1 (en) 2016-05-11 2017-11-16 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
EP3478857A1 (en) 2016-06-29 2019-05-08 Click Diagnostics, Inc. Devices and methods for the detection of molecules using a flow cell
WO2018005870A1 (en) 2016-06-30 2018-01-04 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
EP3707276A4 (en) 2017-11-09 2022-02-23 Visby Medical, Inc. PORTABLE MOLECULAR DIAGNOSTIC DEVICE AND METHODS FOR DETECTING TARGET VIRUSES
US20210299669A1 (en) 2018-09-03 2021-09-30 Visby Medical, Inc. Devices and methods for antibiotic susceptibility testing

Also Published As

Publication number Publication date
US11273443B2 (en) 2022-03-15
US20170259263A1 (en) 2017-09-14
US20180117590A1 (en) 2018-05-03
CN107429281B (zh) 2022-05-27
EP3240906A4 (en) 2018-09-05
US20200406256A1 (en) 2020-12-31
MX2021001972A (es) 2021-04-28
US20210354132A9 (en) 2021-11-18
AU2020217462C1 (en) 2023-02-16
EP4029606A1 (en) 2022-07-20
US20210354131A9 (en) 2021-11-18
US20190193077A1 (en) 2019-06-27
US10112197B2 (en) 2018-10-30
AU2020217462A1 (en) 2020-09-03
US10124334B2 (en) 2018-11-13
US10456783B2 (en) 2019-10-29
US20210039097A1 (en) 2021-02-11
WO2016109691A1 (en) 2016-07-07
CA2972587A1 (en) 2016-07-07
US10052629B2 (en) 2018-08-21
US20210331159A9 (en) 2021-10-28
ES2898103T3 (es) 2022-03-03
CN107429281A (zh) 2017-12-01
US20180071734A1 (en) 2018-03-15
US20160186240A1 (en) 2016-06-30
JP2020188804A (ja) 2020-11-26
EP3240906B1 (en) 2021-08-25
US20190022643A1 (en) 2019-01-24
US10279346B2 (en) 2019-05-07
US20190030532A1 (en) 2019-01-31
US11167285B2 (en) 2021-11-09
US10525469B2 (en) 2020-01-07
MX2017008618A (es) 2018-03-23
US20190232283A1 (en) 2019-08-01
EP3240906A1 (en) 2017-11-08
AU2020217462B2 (en) 2022-08-11
US20170203297A1 (en) 2017-07-20
JP2018505660A (ja) 2018-03-01
AU2015373998A1 (en) 2017-06-29
JP6778194B2 (ja) 2020-10-28
US10112196B2 (en) 2018-10-30
US20220055032A1 (en) 2022-02-24
CN114958990A (zh) 2022-08-30
US9623415B2 (en) 2017-04-18

Similar Documents

Publication Publication Date Title
HK1246826A1 (zh) 用於分子診斷測試的裝置和方法
IL247540A0 (en) System and method for endoscopic measurement
EP3214422A4 (en) Electric-vehicle testing device and method
GB2542079B (en) Ranging measurement apparatus, methods, and systems
GB201409479D0 (en) Molecular diagnostic test for cancer
EP3118607A4 (en) Testing device for fixing-load verification
GB2545861B (en) Combined NMR-resistivity measurement apparatus, systems, and methods
PL3113729T3 (pl) Urządzenie mechanoterapeutyczne i sposób pomiaru
SG11201702250PA (en) Line measurement device and method
EP3043415A4 (en) Sheet-like-battery test device and sheet-like-battery test method
ZA201702133B (en) Test device and method
GB201615078D0 (en) Measurement device and method
TWI561825B (en) Probe device
GB201420222D0 (en) Molecular probes and methods using the same
GB201518615D0 (en) Test methods and apparatus
GB201517837D0 (en) Measuring device and related method
GB2541856B (en) Cable testing device and method
GB201417271D0 (en) Testing devices
SG10201609731TA (en) Ultrasonic testing apparatus
GB201420223D0 (en) Molecular probes and methods using the same
GB201405010D0 (en) Testing methods and apparatus
GB2524029B (en) Systems and methods for testing sensor units
GB201420221D0 (en) Molecular probes and methods using the same
GB201408522D0 (en) Device testing
SG11201610260XA (en) Testing device and testing method