MX2020005701A - Células efectoras inmunitarias potenciadas y usos de las mismas. - Google Patents

Células efectoras inmunitarias potenciadas y usos de las mismas.

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Publication number
MX2020005701A
MX2020005701A MX2020005701A MX2020005701A MX2020005701A MX 2020005701 A MX2020005701 A MX 2020005701A MX 2020005701 A MX2020005701 A MX 2020005701A MX 2020005701 A MX2020005701 A MX 2020005701A MX 2020005701 A MX2020005701 A MX 2020005701A
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MX
Mexico
Prior art keywords
effector cells
immune effector
enhanced immune
enhanced
derivative
Prior art date
Application number
MX2020005701A
Other languages
English (en)
Inventor
Bahram Valamehr
Ryan Bjordahl
Tom Tong Lee
Jode Goodridge
Original Assignee
Fate Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fate Therapeutics Inc filed Critical Fate Therapeutics Inc
Publication of MX2020005701A publication Critical patent/MX2020005701A/es

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Abstract

Se proporcionan métodos y composiciones para obtener células efectoras derivadas funcionalmente potenciadas obtenidas a partir de la diferenciación dirigida de iPSC modificadas genómicamente. Las células derivadas proporcionadas en la presente descripción tienen una edición del genoma estable y funcional que suministra efectos terapéuticos mejorados o potenciados. También se proporcionan composiciones terapéuticas y el uso de las mismas que comprende las células efectoras derivadas funcionalmente potenciadas solas, o con anticuerpos o Inhibidores de punto de control en terapias de combinación.
MX2020005701A 2017-12-22 2018-12-21 Células efectoras inmunitarias potenciadas y usos de las mismas. MX2020005701A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762609827P 2017-12-22 2017-12-22
US201862649781P 2018-03-29 2018-03-29
US201862774052P 2018-11-30 2018-11-30
PCT/US2018/067289 WO2019126748A1 (en) 2017-12-22 2018-12-21 Enhanced immune effector cells and use thereof

Publications (1)

Publication Number Publication Date
MX2020005701A true MX2020005701A (es) 2020-10-28

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Application Number Title Priority Date Filing Date
MX2020005701A MX2020005701A (es) 2017-12-22 2018-12-21 Células efectoras inmunitarias potenciadas y usos de las mismas.

Country Status (12)

Country Link
US (4) US20210087537A1 (es)
EP (2) EP4083192A1 (es)
JP (2) JP7467339B2 (es)
KR (1) KR20200102454A (es)
CN (1) CN111542594A (es)
AU (1) AU2018388413A1 (es)
BR (1) BR112020011017A2 (es)
CA (1) CA3083779A1 (es)
IL (2) IL309585A (es)
MX (1) MX2020005701A (es)
SG (1) SG11202005173SA (es)
WO (1) WO2019126748A1 (es)

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SG11202005173SA (en) 2017-12-22 2020-06-29 Fate Therapeutics Inc Enhanced immune effector cells and use thereof
KR20200127250A (ko) * 2018-03-29 2020-11-10 페이트 세러퓨틱스, 인코포레이티드 조작된 면역 효과기 세포 및 이의 용도
WO2020033464A1 (en) * 2018-08-07 2020-02-13 H. Lee Moffitt Cancer Center And Research Institute Inc. Car t-cells for the treatment of bone metastatic cancer
BR112022000641A2 (pt) * 2019-07-17 2022-03-29 Fate Therapeutics Inc Modificação genética de célula efetora imune e uso da mesma
WO2021062281A2 (en) * 2019-09-25 2021-04-01 Fate Therapeutics, Inc. Multi-targeting effector cells and use thereof
AU2020364139A1 (en) * 2019-10-10 2022-05-26 Arizona Board Of Regents On Behalf Of The University Of Arizona Modified stem cells and methods of use thereof
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WO2022007796A1 (zh) * 2020-07-06 2022-01-13 上海鑫湾生物科技有限公司 共表达IL-21和hrCD16嵌合受体的免疫细胞及其应用
CN113583139A (zh) * 2020-07-06 2021-11-02 上海鑫湾生物科技有限公司 一种嵌合受体及其应用
CN114276995A (zh) * 2020-09-28 2022-04-05 未来智人再生医学研究院(广州)有限公司 一种表达ctla-4阻遏分子的多能干细胞及其衍生物
CN114350611A (zh) * 2020-09-28 2022-04-15 未来智人再生医学研究院(广州)有限公司 表达靶向pd-1/pd-l1的效应rna分子的多能干细胞及其衍生物
CN114457023A (zh) * 2020-10-30 2022-05-10 未来智人再生医学研究院(广州)有限公司 一种表达cd28激活型抗体的多能干细胞及其衍生物与应用
CN114457022A (zh) * 2020-10-30 2022-05-10 未来智人再生医学研究院(广州)有限公司 一种表达ox40激活型抗体的多能干细胞及其衍生物与应用
CN114457025A (zh) * 2020-10-30 2022-05-10 未来智人再生医学研究院(广州)有限公司 一种表达btla阻断物的多能干细胞或其衍生物及应用
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