MX2017009419A - Uso de enzimas con una amplia gama de actividades como medicamentos para favorecer la digestion. - Google Patents

Uso de enzimas con una amplia gama de actividades como medicamentos para favorecer la digestion.

Info

Publication number
MX2017009419A
MX2017009419A MX2017009419A MX2017009419A MX2017009419A MX 2017009419 A MX2017009419 A MX 2017009419A MX 2017009419 A MX2017009419 A MX 2017009419A MX 2017009419 A MX2017009419 A MX 2017009419A MX 2017009419 A MX2017009419 A MX 2017009419A
Authority
MX
Mexico
Prior art keywords
enzymes
medicaments
wide
promoting digestion
activity range
Prior art date
Application number
MX2017009419A
Other languages
English (en)
Inventor
Wolf William HARTMANN Marcus
ALDAG Ingo
Original Assignee
Cilian Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cilian Ag filed Critical Cilian Ag
Publication of MX2017009419A publication Critical patent/MX2017009419A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Se da a conocer una combinación de dos o más enzimas lipasa, y su uso para tratar deficiencia en la digestión de lípidos y / o trastorno digestivo. Al menos una enzima lipasa tiene un pH óptimo a un valor de pH ácido, mientras que al menos otra enzima lipasa tiene un pH óptimo a un valor de pH alcalino.
MX2017009419A 2015-01-22 2016-01-22 Uso de enzimas con una amplia gama de actividades como medicamentos para favorecer la digestion. MX2017009419A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1501081.2A GB201501081D0 (en) 2015-01-22 2015-01-22 Use of enzymes with a wide pH activity range as medicaments for promoting digestion
PCT/EP2016/051341 WO2016116600A1 (en) 2015-01-22 2016-01-22 Use of enzymes with a wide ph activity range as medicaments for promoting digestion

Publications (1)

Publication Number Publication Date
MX2017009419A true MX2017009419A (es) 2018-01-18

Family

ID=52673797

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017009419A MX2017009419A (es) 2015-01-22 2016-01-22 Uso de enzimas con una amplia gama de actividades como medicamentos para favorecer la digestion.

Country Status (13)

Country Link
US (2) US10590402B2 (es)
EP (1) EP3247385A1 (es)
JP (1) JP7075758B2 (es)
KR (1) KR102601352B1 (es)
CN (1) CN107872978B (es)
AU (1) AU2016208474B9 (es)
BR (1) BR112017015782A2 (es)
CA (1) CA2992918A1 (es)
GB (1) GB201501081D0 (es)
IL (1) IL253618B (es)
MX (1) MX2017009419A (es)
RU (1) RU2721708C2 (es)
WO (1) WO2016116600A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201501081D0 (en) 2015-01-22 2015-03-11 Cilian Ag Use of enzymes with a wide pH activity range as medicaments for promoting digestion
EP4172325A1 (en) * 2020-06-24 2023-05-03 Cilian AG New lipase enzyme
AU2022254851A1 (en) 2021-04-09 2023-11-23 Cilian Ag Purification of proteins

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991180A (en) * 1972-03-06 1976-11-09 Rohm And Haas Company Stabilization of internally administered pancreatic lipase
SE454566B (sv) 1984-04-24 1988-05-16 Lars G I Hellgren Farmaceutisk komposition innehallande en verksam mengd av vattenlosliga proteinaser som extraherats fran ett vattenlevande djur valt av ordningen euphausiaceae eller slektet mallotus
US4944944A (en) 1987-11-19 1990-07-31 Oklahoma Medical Research Foundation Dietary compositions and methods using bile salt-activated lipase
DK173590D0 (da) 1990-06-06 1990-07-19 Novo Nordisk As Rekombinante terapeutiske lipaser
FR2699179B1 (fr) 1992-12-16 1995-01-06 Jouveinal Inst Rech Acides nucléiques codant pour la lipase gastrique de chien et dérivés polypeptidiques, leur utilisation pour la production de ces polypeptides, et compositions pharmaceutiques à base de ces derniers.
ES2236738T3 (es) * 1995-05-31 2005-07-16 Medzyme N.V. Composicion para mejorar la digestibilidad y la utilizacion de nutrientes.
EP1151118B1 (en) 1999-02-04 2008-04-09 The University Of Georgia Research Foundation, Inc. Recombinant expression of heterologous nucleic acids in protozoa
US7238355B1 (en) * 1999-02-26 2007-07-03 Kirin Beer Kabushiki Kaisha Coated material and process for producing the coated material
US20010010928A1 (en) 1999-03-26 2001-08-02 Stephen M. Beverley Protozoan expression system
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
RU2299074C2 (ru) * 2000-11-02 2007-05-20 Цилиан Аг Применение полученных из инфузорий ферментов в качестве способствующих пищеварению лекарственных средств
AR032392A1 (es) 2001-01-19 2003-11-05 Solvay Pharm Gmbh Mezcla de enzimas, preparado farmaceutico y utilizacion de dicho preparado.
DE10106660A1 (de) * 2001-02-12 2002-08-29 Celanese Ventures Gmbh Verfahren zur Herstellung von gamma-Linolensäure aus einer Ciliaten-Kultur durch Zusatz geeigneter Vorläufermoleküle zu dem Kulturmedium
US6534303B2 (en) 2001-03-13 2003-03-18 Council Of Scientific & Industrial Research Process for the preparation of acidic lipase
DK1570060T3 (da) * 2002-12-02 2007-11-05 Basf Ag L-rhamnoseinducerbare ekspressionssystemer
EP1612596A1 (en) 2004-06-29 2006-01-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. High-efficient, tuneable and switchable optical elements based on polymer-liquid crystal composites and films, mixtures and a method for their production
JP4394598B2 (ja) * 2004-08-24 2010-01-06 日清オイリオグループ株式会社 リパーゼ粉末組成物及びそれを用いたエステル化物の製造方法
SI1809320T1 (sl) 2004-10-14 2010-11-30 Cystic Fibrosis Foundation Therapeutics Inc Sestavki ki vsebujejo lipazo proteazo in amilazo za zdravljenje pankreasne insuficience
ATE498690T1 (de) 2005-07-13 2011-03-15 Cilian Ag Hitzeinduzierbare tetrahymena-promotoren und deren verwendung
US8071089B2 (en) * 2005-11-01 2011-12-06 Bio-Cat, Inc. Composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrosis as well as people suffering from pancreatic lipase insufficiency
PT2079445E (pt) * 2007-02-20 2016-02-29 Allergan Pharmaceuticals Internat Ltd Composições de enzimas digestivas estáveis
FR2918846B1 (fr) 2007-07-20 2013-07-26 Isl Innovation Sante Lipides Composition alimentaire pour ameliorer la digestibilite des lipides alimentaires
US7790429B2 (en) 2007-11-28 2010-09-07 Transbiodiesel Ltd. Robust multi-enzyme preparation for the synthesis of fatty acid alkyl esters
US8268305B1 (en) 2011-09-23 2012-09-18 Bio-Cat, Inc. Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase
CN102660528A (zh) * 2012-05-16 2012-09-12 苏州先阔生物科技有限公司 复合碱性脂肪酶组合物、肠溶片及其应用
CN104031899B (zh) 2013-03-05 2016-04-13 中国科学院天津工业生物技术研究所 一种脂肪酶及其应用
CN103266094B (zh) 2013-05-23 2015-02-25 天宁香料（江苏）有限公司 一种复合脂肪酶及其应用
CN105524905A (zh) * 2014-09-29 2016-04-27 湖南新鸿鹰生物工程有限公司 一种含酸性蛋白酶的酱油复合酶及其制备方法
GB201501081D0 (en) 2015-01-22 2015-03-11 Cilian Ag Use of enzymes with a wide pH activity range as medicaments for promoting digestion

Also Published As

Publication number Publication date
RU2017129598A3 (es) 2019-02-21
BR112017015782A2 (pt) 2018-03-27
CN107872978A (zh) 2018-04-03
CA2992918A1 (en) 2016-07-28
US10590402B2 (en) 2020-03-17
AU2016208474B2 (en) 2021-04-01
KR20170105104A (ko) 2017-09-18
WO2016116600A1 (en) 2016-07-28
US20200071683A1 (en) 2020-03-05
CN107872978B (zh) 2021-11-26
US11584920B2 (en) 2023-02-21
RU2721708C2 (ru) 2020-05-21
KR102601352B1 (ko) 2023-11-10
GB201501081D0 (en) 2015-03-11
US20180073001A1 (en) 2018-03-15
IL253618B (en) 2021-10-31
JP7075758B2 (ja) 2022-05-26
JP2018504118A (ja) 2018-02-15
AU2016208474A1 (en) 2017-09-07
EP3247385A1 (en) 2017-11-29
RU2017129598A (ru) 2019-02-21
IL253618A0 (en) 2017-09-28
AU2016208474B9 (en) 2021-04-22

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