MX2017008170A - Metodo para sintetizar compuestos de carbonilo opticamente activos. - Google Patents

Metodo para sintetizar compuestos de carbonilo opticamente activos.

Info

Publication number
MX2017008170A
MX2017008170A MX2017008170A MX2017008170A MX2017008170A MX 2017008170 A MX2017008170 A MX 2017008170A MX 2017008170 A MX2017008170 A MX 2017008170A MX 2017008170 A MX2017008170 A MX 2017008170A MX 2017008170 A MX2017008170 A MX 2017008170A
Authority
MX
Mexico
Prior art keywords
aryl
optically active
carbonyl compound
carbonyl compounds
prochiral
Prior art date
Application number
MX2017008170A
Other languages
English (en)
Inventor
Schelwies Mathias
Paciello Rocco
Seeber Georg
Keller Andreas
Bey Oliver
Renz Stephanie
Haubner Martin
Heydrich Gunnar
Wegner Guenter
Dieter Tebben Gerd-
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of MX2017008170A publication Critical patent/MX2017008170A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C07C29/172—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds with the obtention of a fully saturated alcohol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/56—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by isomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La presente invención se refiere a un proceso para la preparación de un compuesto de carbonilo ópticamente activo por hidrogenación asimétrica de un compuesto de carbonilo a,ß-no saturado proquiral con hidrógeno en presencia de al menos un catalizador de metal de transición ópticamente activo que es soluble en la mezcla de reacción y que tiene rodio como metal de transición catalíticamente activo y un ligando de bisfosfina bidentado quiral, donde la mezcla de reacción durante la hidrogenación del compuesto de carbonilo a,ß-no saturado proquiral comprende adicionalmente al menos un compuesto de la fórmula general (I): (ver Fórmula) donde R1, R2: son idénticos o diferentes y son arilo C6 a C10 que no está sustituido o lleva uno o más, por ejemplo 1, 2, 3, 4 o 5, sustituyentes que se seleccionan de alquilo C1 a C6, cicloalquilo C3 a C6, arilo C6 a C10, alcoxi C1 a C6 y amino; Z es un grupo CHR3R4 o arilo que no está sustituido o lleva uno o más, por ejemplo 1, 2, 3, 4 o 5, sustituyentes que se seleccionan de alquilo C1 a C6, cicloalquilo C3 a C6, arilo C6 a C10, alcoxi C1 a C6 y amino, donde R3 y R4 son como se definen en las reivindicaciones y la descripción.
MX2017008170A 2014-12-19 2015-12-18 Metodo para sintetizar compuestos de carbonilo opticamente activos. MX2017008170A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14199410 2014-12-19
PCT/EP2015/080392 WO2016097242A1 (de) 2014-12-19 2015-12-18 Verfahren zur herstellung optisch aktiver carbonylverbindungen

Publications (1)

Publication Number Publication Date
MX2017008170A true MX2017008170A (es) 2017-09-18

Family

ID=52231936

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017008170A MX2017008170A (es) 2014-12-19 2015-12-18 Metodo para sintetizar compuestos de carbonilo opticamente activos.

Country Status (7)

Country Link
US (3) US9975837B2 (es)
EP (2) EP3233778B1 (es)
JP (1) JP6702974B2 (es)
CN (1) CN107250091B (es)
ES (2) ES2727384T3 (es)
MX (1) MX2017008170A (es)
WO (1) WO2016097242A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017014148A (es) 2015-05-04 2018-03-15 Basf Se Proceso para la preparacion de melonal.
EP3362426B1 (en) 2015-10-12 2020-09-02 Basf Se Hydroformylation process for producing 1,6-disubstituted hexane derivatives
PL3386919T3 (pl) 2015-12-08 2022-02-21 Basf Se Zawierający cynę materiał zeolitowy o strukturze szkieletowej bea
ES2844182T3 (es) 2016-06-07 2021-07-21 Basf Se Procedimiento para la preparación de alcoholes con insaturación en posición 2,3
BR112018075784B1 (pt) 2016-06-29 2022-06-28 Basf Se Processo para preparação de aldeídos alfa, beta insaturados
CN109790080B (zh) 2016-10-06 2023-04-07 巴斯夫欧洲公司 从对映体混合物中富集对映体的方法
US11111197B2 (en) * 2017-12-21 2021-09-07 Basf Se Process for the preparation of alpha, beta unsaturated aldehydes by oxidation of alcohols in the presence of a liquid phase
ES2934908T3 (es) * 2018-09-05 2023-02-27 Basf Se Reactor para llevar a cabo una reacción bifásica de gas/líquido de alta presión con un medio espumante
CN112654421B (zh) * 2018-09-05 2023-05-09 巴斯夫欧洲公司 用于进行两种不同密度的不混溶流体之间的反应的反应器
CN112638854B (zh) * 2018-09-05 2023-10-27 巴斯夫欧洲公司 通过不对称氢化连续制备光学活性羰基化合物
WO2020048998A1 (de) * 2018-09-05 2020-03-12 Basf Se Verfahren zur durchführung einer gas/flüssig-zweiphasigen hochdruckreaktion
EP3976570A1 (en) * 2019-05-27 2022-04-06 DSM IP Assets B.V. Selective hydrogenation of alkynes to alkenes in the presence of a phosphorus compound and an organic sulphur compound
CN111056932A (zh) * 2019-12-09 2020-04-24 万华化学集团股份有限公司 一种制备光学活性香茅醛的方法
CN110872217A (zh) * 2019-12-09 2020-03-10 万华化学集团股份有限公司 一种光学活性的香茅醛的制备方法
CN111004102B (zh) * 2019-12-23 2022-11-04 万华化学集团股份有限公司 一种制备光学活性香茅醛的方法及用于该方法的催化剂
CN111056933B (zh) * 2019-12-24 2022-11-08 万华化学集团股份有限公司 一种制备光学活性香茅醛的方法及用于该方法的催化剂体系
CN111792986B (zh) * 2020-07-22 2022-09-20 万华化学集团股份有限公司 一种制备r-香茅醛的方法
CN112142583B (zh) * 2020-10-26 2022-07-26 万华化学集团股份有限公司 一种香叶醛制备橙花醛的方法
CN113527367B (zh) * 2021-07-14 2022-08-02 南开沧州渤海新区绿色化工研究有限公司 一种含四（3,5-二三氟甲基苯基）硼阴离子的手性双膦配体铑络合物和制备方法及应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5278812A (en) 1975-12-26 1977-07-02 Nikki Chem Co Ltd Selective production method of saturated aldehyde
FR2396735A1 (fr) 1977-07-04 1979-02-02 Rhone Poulenc Ind Procede de preparation de citronellal optiquement actif
DE19854637A1 (de) 1998-11-26 2000-05-31 Basf Ag Reaktor zur kontinuierlichen Durchführung von Gas-Flüssig-, Flüssig-Flüssig- oder Gas-Flüssig-Fest-Reaktionen
JP4676617B2 (ja) 2001-01-18 2011-04-27 高砂香料工業株式会社 イソプレゴールの製造方法
DE102004049631A1 (de) 2004-10-11 2006-04-20 Basf Ag Verfahren zur Herstellung optisch aktiver Carbonylverbindungen
DE102004057277A1 (de) 2004-11-26 2006-06-01 Basf Ag Verfahren zur Herstellung von Menthol
ES2636840T3 (es) 2007-04-25 2017-10-09 Basf Se Procedimiento para la preparación de compuestos carbonílicos ópticamente activos
AR070176A1 (es) * 2008-01-17 2010-03-17 Novartis Ag Procesos de sintesis de inhibidores de nep, compuestos intermediarios y uso de los mismos en la sintesis
JP5711209B2 (ja) * 2010-03-04 2015-04-30 高砂香料工業株式会社 均一系不斉水素化触媒

Also Published As

Publication number Publication date
US9975837B2 (en) 2018-05-22
EP3233778A1 (de) 2017-10-25
ES2883557T3 (es) 2021-12-09
EP3489213A1 (de) 2019-05-29
US20180057437A1 (en) 2018-03-01
EP3489213B1 (de) 2021-04-28
JP2017537965A (ja) 2017-12-21
CN107250091A (zh) 2017-10-13
EP3233778B1 (de) 2019-02-20
WO2016097242A1 (de) 2016-06-23
US20180244598A1 (en) 2018-08-30
CN107250091B (zh) 2021-05-04
USRE49036E1 (en) 2022-04-19
JP6702974B2 (ja) 2020-06-03
ES2727384T3 (es) 2019-10-15
US10301244B2 (en) 2019-05-28

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