MX2016011495A - Composicion y metodo para estabilizar acidos nucleicos en muestras biologicas. - Google Patents
Composicion y metodo para estabilizar acidos nucleicos en muestras biologicas.Info
- Publication number
- MX2016011495A MX2016011495A MX2016011495A MX2016011495A MX2016011495A MX 2016011495 A MX2016011495 A MX 2016011495A MX 2016011495 A MX2016011495 A MX 2016011495A MX 2016011495 A MX2016011495 A MX 2016011495A MX 2016011495 A MX2016011495 A MX 2016011495A
- Authority
- MX
- Mexico
- Prior art keywords
- biological samples
- composition
- nucleic acids
- stabilizing
- stabilizing nucleic
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Se divulgan métodos, composiciones y kits para estabilizar el ácido desoxirribonucleico (ADN) tanto humano como microbiano presente en muestras biológicas complejas, tales como heces. En particular, se divulgan composiciones acuosas para estabilizar el ADN contenido en las muestras biológicas a temperatura ambiente, junto con métodos asociados y kits usando la misma. En un aspecto, las composiciones comprenden un agente quelante en una concentración de por lo menos alrededor de 150 mM, y la composición tiene un pH de al menos alrededor de 9.5.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461949692P | 2014-03-07 | 2014-03-07 | |
US201462057769P | 2014-09-30 | 2014-09-30 | |
PCT/CA2015/050173 WO2015131291A1 (en) | 2014-03-07 | 2015-03-06 | Composition and method for stabilizing nucleic acids in biological samples |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016011495A true MX2016011495A (es) | 2017-07-11 |
Family
ID=54054312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016011495A MX2016011495A (es) | 2014-03-07 | 2015-03-06 | Composicion y metodo para estabilizar acidos nucleicos en muestras biologicas. |
Country Status (18)
Country | Link |
---|---|
US (2) | US10435735B2 (es) |
EP (1) | EP3114225B1 (es) |
JP (1) | JP6670765B2 (es) |
KR (1) | KR102392407B1 (es) |
CN (1) | CN106255753B (es) |
AU (1) | AU2015226811B2 (es) |
CA (1) | CA2941764C (es) |
DK (1) | DK3114225T3 (es) |
ES (1) | ES2880310T3 (es) |
IL (1) | IL247662A0 (es) |
MX (1) | MX2016011495A (es) |
PL (1) | PL3114225T3 (es) |
PT (1) | PT3114225T (es) |
RU (1) | RU2717644C2 (es) |
SA (2) | SA521421271B1 (es) |
SG (2) | SG11201607364RA (es) |
WO (1) | WO2015131291A1 (es) |
ZA (1) | ZA201906139B (es) |
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AU2018373247B2 (en) | 2017-11-22 | 2023-11-30 | Ancestry. Com Dna, Llc | Sample collection kit including cap having selectively movable sleeve |
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