MX366113B - Metodos de diganostico y composiciones. - Google Patents

Metodos de diganostico y composiciones.

Info

Publication number
MX366113B
MX366113B MX2017003475A MX2017003475A MX366113B MX 366113 B MX366113 B MX 366113B MX 2017003475 A MX2017003475 A MX 2017003475A MX 2017003475 A MX2017003475 A MX 2017003475A MX 366113 B MX366113 B MX 366113B
Authority
MX
Mexico
Prior art keywords
compositions
diagnostic methods
methods
thermocycling
primers
Prior art date
Application number
MX2017003475A
Other languages
English (en)
Other versions
MX2017003475A (es
Inventor
Tabakman Scott
Lee Josephine
Belhocine Kamila
Richardson Aaron
Wu Indira
Patel Pranav
Original Assignee
Theranos Ip Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2014/056151 external-priority patent/WO2015076919A1/en
Application filed by Theranos Ip Co Llc filed Critical Theranos Ip Co Llc
Publication of MX2017003475A publication Critical patent/MX2017003475A/es
Publication of MX366113B publication Critical patent/MX366113B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La presente invención se refiere a métodos y composiciones para la identificación de información de relación genética. Al menos porciones de los métodos proporcionados en la presente se pueden realizar sin termociclaje. Las composiciones y métodos pueden incluir reactivos tal como polimerasas de ácidos nucleicos y cebadores.
MX2017003475A 2014-09-17 2015-09-17 Metodos de diganostico y composiciones. MX366113B (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462051945P 2014-09-17 2014-09-17
US201462051912P 2014-09-17 2014-09-17
PCT/US2014/056151 WO2015076919A1 (en) 2013-11-22 2014-09-17 Nucleic Acid Amplification
US201462068605P 2014-10-24 2014-10-24
US201462068603P 2014-10-24 2014-10-24
US201562151358P 2015-04-22 2015-04-22
PCT/US2015/050811 WO2016044664A1 (en) 2014-09-17 2015-09-17 Diagnostic methods and compositions

Publications (2)

Publication Number Publication Date
MX2017003475A MX2017003475A (es) 2017-08-02
MX366113B true MX366113B (es) 2019-06-26

Family

ID=55533878

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017003473A MX2017003473A (es) 2014-09-17 2015-09-17 Amplificacion hibrida de acido nucleico en multiples pasos.
MX2017003475A MX366113B (es) 2014-09-17 2015-09-17 Metodos de diganostico y composiciones.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2017003473A MX2017003473A (es) 2014-09-17 2015-09-17 Amplificacion hibrida de acido nucleico en multiples pasos.

Country Status (8)

Country Link
US (3) US9909193B2 (es)
EP (2) EP3194629A4 (es)
JP (6) JP2017532030A (es)
CN (3) CN108026591B (es)
BR (1) BR112017005392A2 (es)
CA (2) CA2960859A1 (es)
MX (2) MX2017003473A (es)
WO (2) WO2016044673A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108026591B (zh) 2014-09-17 2021-09-07 赛拉诺斯知识产权有限责任公司 诊断方法和组合物
US10822648B1 (en) 2016-07-29 2020-11-03 Labrador Diagnostics Llc Hybrid multi-step nucleic acid amplification
BR112019012057A2 (pt) 2016-12-15 2019-11-12 Meharry Medical College agente antiviral, composição farmacêutica para a administração do mesmo e métodos de redução na replicação do vírus zika (zikv) e tratamento de doença mediada pelo vírus zika (zikv)
FI130673B1 (en) * 2020-11-24 2024-01-11 Mobidiag Oy Method and system for performing a cumulative nucleic acid amplification reaction

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
WO1997045559A1 (en) * 1996-05-29 1997-12-04 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US6743605B1 (en) * 1998-06-24 2004-06-01 Enzo Life Sciences, Inc. Linear amplification of specific nucleic acid sequences
ES2546450T3 (es) * 2000-04-07 2015-09-23 Eiken Kagaku Kabushiki Kaisha Método para amplificar y detectar un ácido nucleico usando ácido nucleico bicatenario como molde
US6605451B1 (en) * 2000-06-06 2003-08-12 Xtrana, Inc. Methods and devices for multiplexing amplification reactions
US7041447B2 (en) * 2001-04-09 2006-05-09 St. Jude Children's Hospital, Inc. Haplotyping method for multiple distal nucleotide polymorphisms
EP1319718A1 (en) * 2001-12-14 2003-06-18 Keygene N.V. High throughput analysis and detection of multiple target sequences
WO2005014810A1 (ja) * 2003-08-08 2005-02-17 National Institute Of Advanced Industrial Science And Technology ダンベル型ｄｎａの効率的な製造方法
JP4379087B2 (ja) * 2003-11-07 2009-12-09 トヨタ自動車株式会社 ゲラニルゲラニル二リン酸合成酵素及びゲラニルゲラニオールの製造方法
WO2005095654A1 (en) * 2004-03-25 2005-10-13 Biohelix Corporation Helicase-dependent amplification of circular nucleic acids
JP4644685B2 (ja) * 2004-07-02 2011-03-02 株式会社ダナフォーム 塩基配列タグの調製方法
WO2007041201A2 (en) * 2005-10-03 2007-04-12 Applera Corporation Compositions, methods, and kits for amplifying nucleic acids
CA2691360A1 (en) * 2007-06-22 2008-12-31 Stephen A. Brown Specific amplification of tumor specific dna sequences
CN103323610B (zh) 2007-10-02 2016-12-28 赛拉诺斯股份有限公司 模块化现场护理装置及其应用
US20120115140A1 (en) * 2009-04-29 2012-05-10 Js Genetics Inc. Molecular Diagnosis of Fragile X Syndrome Associated with FMR1 Gene
IT1394539B1 (it) * 2009-05-19 2012-07-05 Sentinel Ch S P A Uso di uno stabilizzante delle polimerasi per la liofilizzazione e la preparazione di kit pronti per l'uso
WO2012038049A2 (en) * 2010-09-22 2012-03-29 Roche Diagnostics Gmbh Amplification of distant nucleic acid targets using engineered primers
CN102242211A (zh) * 2011-07-08 2011-11-16 无锡锐奇基因生物科技有限公司 检测突变核酸序列的方法及试剂盒
US9619627B2 (en) 2011-09-25 2017-04-11 Theranos, Inc. Systems and methods for collecting and transmitting assay results
US8380541B1 (en) 2011-09-25 2013-02-19 Theranos, Inc. Systems and methods for collecting and transmitting assay results
US8435738B2 (en) 2011-09-25 2013-05-07 Theranos, Inc. Systems and methods for multi-analysis
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US9250229B2 (en) 2011-09-25 2016-02-02 Theranos, Inc. Systems and methods for multi-analysis
KR20140082756A (ko) 2011-09-25 2014-07-02 테라노스, 인코포레이티드 다중분석을 위한 시스템과 방법
WO2014025337A1 (en) * 2012-08-06 2014-02-13 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Methods and reagents for amplifying nucleic acids
JP2014140367A (ja) * 2012-12-27 2014-08-07 Tosoh Corp Ｂ型肝炎ウイルスｄｎａ増幅用プライマーおよびそれを用いたｂ型肝炎ウイルスｄｎａ検出法
EP2971123B1 (en) 2013-03-15 2021-05-05 Labrador Diagnostics LLC Nucleic acid amplification
US9217167B2 (en) * 2013-07-26 2015-12-22 General Electric Company Ligase-assisted nucleic acid circularization and amplification
JP2017500020A (ja) 2013-11-22 2017-01-05 セラノス， インコーポレイテッド 核酸増幅
CN108026591B (zh) 2014-09-17 2021-09-07 赛拉诺斯知识产权有限责任公司 诊断方法和组合物

Also Published As

Publication number Publication date
CA2960859A1 (en) 2016-03-24
JP2017531424A (ja) 2017-10-26
JP2017532030A (ja) 2017-11-02
CN107002066A (zh) 2017-08-01
EP3194590A4 (en) 2018-05-09
CN113736863A (zh) 2021-12-03
US20160201148A1 (en) 2016-07-14
EP3194590A1 (en) 2017-07-26
JP2022110152A (ja) 2022-07-28
US20170342476A1 (en) 2017-11-30
MX2017003473A (es) 2017-08-02
JP2021006056A (ja) 2021-01-21
CN108026591B (zh) 2021-09-07
WO2016044664A1 (en) 2016-03-24
WO2016044673A1 (en) 2016-03-24
BR112017005392A2 (pt) 2017-12-12
CN108026591A (zh) 2018-05-11
JP2021000138A (ja) 2021-01-07
JP2023011943A (ja) 2023-01-24
EP3194629A1 (en) 2017-07-26
CA2961209A1 (en) 2016-03-24
MX2017003475A (es) 2017-08-02
EP3194629A4 (en) 2018-03-07
US20180223381A1 (en) 2018-08-09
US9909193B2 (en) 2018-03-06

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Owner name: THERANOS IP COMPANY, LLC

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