MX2018013791A - Metodos y composiciones para caracterizar bacterias resistentes a farmacos a partir de muestras biologicas fijadas con formalina e incluidas en parafina. - Google Patents

Metodos y composiciones para caracterizar bacterias resistentes a farmacos a partir de muestras biologicas fijadas con formalina e incluidas en parafina.

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Publication number
MX2018013791A
MX2018013791A MX2018013791A MX2018013791A MX2018013791A MX 2018013791 A MX2018013791 A MX 2018013791A MX 2018013791 A MX2018013791 A MX 2018013791A MX 2018013791 A MX2018013791 A MX 2018013791A MX 2018013791 A MX2018013791 A MX 2018013791A
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MX
Mexico
Prior art keywords
formalin
drug resistant
compositions
fixed paraffin
methods
Prior art date
Application number
MX2018013791A
Other languages
English (en)
Inventor
Zhou Yi
Jung Daniel
RAO Kakuturu
Original Assignee
American Molecular Laboratories Inc
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Publication date
Application filed by American Molecular Laboratories Inc filed Critical American Molecular Laboratories Inc
Publication of MX2018013791A publication Critical patent/MX2018013791A/es

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    • CCHEMISTRY; METALLURGY
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    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La invención proporciona métodos y composiciones generalmente útiles para el uso de la amplificación por reacción en cadena de la polimerasa (PCR) de secuencias de ADN trazas a partir de muestras de biopsia fijadas con formalina e incluidas en parafina (FFPE) y especificamente relevantes para la identificación de H. pylori resistente a múltiples fármacos en tales muestras de biopsia.
MX2018013791A 2016-05-10 2017-05-10 Metodos y composiciones para caracterizar bacterias resistentes a farmacos a partir de muestras biologicas fijadas con formalina e incluidas en parafina. MX2018013791A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662334185P 2016-05-10 2016-05-10
PCT/US2017/031901 WO2017196941A1 (en) 2016-05-10 2017-05-10 Methods and compositions for characterizing drug resistant bacteria from formalin-fixed paraffin-embedded biological samples

Publications (1)

Publication Number Publication Date
MX2018013791A true MX2018013791A (es) 2019-08-05

Family

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Family Applications (1)

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MX2018013791A MX2018013791A (es) 2016-05-10 2017-05-10 Metodos y composiciones para caracterizar bacterias resistentes a farmacos a partir de muestras biologicas fijadas con formalina e incluidas en parafina.

Country Status (10)

Country Link
US (1) US10968489B2 (es)
EP (1) EP3455380B1 (es)
JP (1) JP7143284B2 (es)
KR (1) KR102326351B1 (es)
CN (1) CN109312410B (es)
AU (1) AU2017262776B2 (es)
CA (1) CA3023685A1 (es)
ES (1) ES2886270T3 (es)
MX (1) MX2018013791A (es)
WO (1) WO2017196941A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019099775A1 (en) * 2017-11-16 2019-05-23 American Molecular Laboratories, Inc. Methods for detection of antibiotic resistant h.pylori
CN109141963B (zh) * 2018-09-27 2023-12-19 上海海洋大学 一种同位素测定样品痕量取样及包埋器具
MX2021014335A (es) * 2019-05-23 2022-03-25 American Molecular Laboratories Inc Metodos para detectar un nivel de h. pylori en una muestra fecal.
CN110184331A (zh) * 2019-05-27 2019-08-30 深圳前海大井医疗股份有限公司 幽门螺杆菌阴阳性与克拉霉素耐药性同步检测法
CN110423799A (zh) * 2019-08-12 2019-11-08 复旦大学 一种幽门螺杆菌左氧氟沙星耐药检测方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040052799A1 (en) 1996-11-15 2004-03-18 Astra Aktiebolag Nucleic acid and amino acid sequences relating to Helicobacter pylori for diagnostics and therapeutics
US6677153B2 (en) * 1999-11-29 2004-01-13 Avi Biopharma, Inc. Antisense antibacterial method and composition
CN103534591B (zh) * 2010-10-26 2016-04-06 利兰·斯坦福青年大学托管委员会 通过测序分析进行的非侵入性胎儿遗传筛选
EP2702170B1 (en) * 2011-04-28 2015-12-16 Life Technologies Corporation Methods and compositions for multiplex pcr
US20130059762A1 (en) * 2011-04-28 2013-03-07 Life Technologies Corporation Methods and compositions for multiplex pcr
US10465238B2 (en) * 2013-12-19 2019-11-05 The Board Of Trustees Of The Leland Stanford Junior University Quantification of mutant alleles and copy number variation using digital PCR with nonspecific DNA-binding dyes
EP3201356A1 (en) * 2014-10-03 2017-08-09 Life Technologies Corporation Genetic sequence verification compositions, methods and kits
CN104846097B (zh) 2015-05-21 2017-12-22 杭州千基生物科技有限公司 幽门螺旋杆菌分型与耐药突变基因检测试剂盒
CN105368825B (zh) * 2015-10-14 2019-09-10 华东医院 幽门螺杆菌抗生素耐药性分析试剂盒及耐药性检测方法

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Publication number Publication date
JP7143284B2 (ja) 2022-09-28
AU2017262776B2 (en) 2023-07-06
CA3023685A1 (en) 2017-11-16
CN109312410B (zh) 2022-10-28
JP2019514438A (ja) 2019-06-06
WO2017196941A1 (en) 2017-11-16
ES2886270T3 (es) 2021-12-16
CN109312410A (zh) 2019-02-05
KR20190003739A (ko) 2019-01-09
KR102326351B1 (ko) 2021-11-12
EP3455380B1 (en) 2021-07-07
US20170327873A1 (en) 2017-11-16
AU2017262776A1 (en) 2018-12-06
EP3455380A4 (en) 2020-03-11
EP3455380A1 (en) 2019-03-20
US10968489B2 (en) 2021-04-06

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