MX2016006457A - Analisis de cromatografia liquida de alto rendimiento (hplc) de impurezas en dianhidrogalactitol. - Google Patents
Analisis de cromatografia liquida de alto rendimiento (hplc) de impurezas en dianhidrogalactitol.Info
- Publication number
- MX2016006457A MX2016006457A MX2016006457A MX2016006457A MX2016006457A MX 2016006457 A MX2016006457 A MX 2016006457A MX 2016006457 A MX2016006457 A MX 2016006457A MX 2016006457 A MX2016006457 A MX 2016006457A MX 2016006457 A MX2016006457 A MX 2016006457A
- Authority
- MX
- Mexico
- Prior art keywords
- dianhydrogalactitol
- hplc
- impurities
- preparations
- hplc analysis
- Prior art date
Links
- AAFJXZWCNVJTMK-GUCUJZIJSA-N (1s,2r)-1-[(2s)-oxiran-2-yl]-2-[(2r)-oxiran-2-yl]ethane-1,2-diol Chemical compound C([C@@H]1[C@H](O)[C@H](O)[C@H]2OC2)O1 AAFJXZWCNVJTMK-GUCUJZIJSA-N 0.000 title abstract 5
- 229950000758 dianhydrogalactitol Drugs 0.000 title abstract 5
- 238000004128 high performance liquid chromatography Methods 0.000 title abstract 4
- 239000012535 impurity Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 3
- 238000004458 analytical method Methods 0.000 abstract 2
- 238000000105 evaporative light scattering detection Methods 0.000 abstract 2
- 238000002953 preparative HPLC Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000004885 tandem mass spectrometry Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
- G01N2030/8447—Nebulising, aerosol formation or ionisation
- G01N2030/8494—Desolvation chambers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8872—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample impurities
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/083,135 US9029164B2 (en) | 2012-02-27 | 2013-11-18 | Analytical methods for analyzing and determining impurities in dianhydrogalactitol |
| PCT/US2014/066087 WO2015074025A1 (en) | 2013-11-18 | 2014-11-18 | Hplc analysis of impurities in dianhydrogalactitol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2016006457A true MX2016006457A (es) | 2017-01-06 |
Family
ID=53058168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016006457A MX2016006457A (es) | 2013-11-18 | 2014-11-18 | Analisis de cromatografia liquida de alto rendimiento (hplc) de impurezas en dianhidrogalactitol. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP3071555A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2016538574A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20160108315A (cg-RX-API-DMAC7.html) |
| CN (1) | CN107529337B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2014348232A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2931088A1 (cg-RX-API-DMAC7.html) |
| CL (1) | CL2016001197A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL245713A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2016006457A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015074025A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106397360A (zh) * | 2015-07-29 | 2017-02-15 | 广西梧州制药（集团）股份有限公司 | 叔丁醇在去水卫矛醇或其组合物冷冻干燥过程中的应用 |
| BR112018010634B1 (pt) * | 2015-11-25 | 2022-01-18 | Del Mar Pharmaceuticals (Bc) Ltd | Método analítico |
| CN105445407B (zh) * | 2015-12-29 | 2017-04-19 | 成都普思生物科技股份有限公司 | 一种山桐子中脂肪酸和维生素e的检测方法 |
| US10927363B2 (en) | 2016-04-04 | 2021-02-23 | Mie University | DNA sequence and expression vector for alginate lyase |
| KR102270026B1 (ko) * | 2020-01-31 | 2021-06-28 | 현대약품 주식회사 | (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법 |
| CN114113352A (zh) * | 2020-08-28 | 2022-03-01 | 深圳波顿香料有限公司 | 发酵液中内酯型槐糖酯含量的测定方法 |
| JP2023138462A (ja) | 2022-03-16 | 2023-10-02 | 国立大学法人三重大学 | ４－デオキシ－ｌ－エリスロ－５－ヘキソセウロース・ウロン酸の新規用途 |
| CN120741731B (zh) * | 2025-09-08 | 2025-11-14 | 天津中医药大学 | 一种基于uplc-qtrap-ms/ms检测扶芳藤或复方扶芳藤合剂中化学成分的方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04297868A (ja) * | 1991-03-27 | 1992-10-21 | Tonen Corp | オリゴ糖の分析方法 |
| JPH09229920A (ja) * | 1996-02-26 | 1997-09-05 | Kao Corp | グラジェント液体クロマトグラフィー溶離液の処理方法 |
| US6060525A (en) * | 1996-03-01 | 2000-05-09 | Dionix Corporation | Removal of borate in chromatography |
| WO2000042225A1 (en) * | 1999-01-14 | 2000-07-20 | Board Of Supervisors Of Louisiana State Universityand Agricultural And Mechanical College | Process for the separation of sugars |
| US20060148732A1 (en) * | 2000-11-17 | 2006-07-06 | Gutterman Jordan U | Inhibition of NF-kappaB by triterpene compositions |
| JP2004294384A (ja) * | 2003-03-28 | 2004-10-21 | National Agriculture & Bio-Oriented Research Organization | １−デオキシノジリマイシンの測定方法 |
| EP1660039B1 (en) * | 2003-07-18 | 2016-09-28 | Oakwood Laboratories L.L.C. | Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions |
| BRPI0511442A (pt) * | 2004-05-20 | 2007-12-26 | Chiron Srl | análise de eluatos por cromatografia lìquida |
| JP2008076340A (ja) * | 2006-09-25 | 2008-04-03 | Toppan Printing Co Ltd | 高感度検出方法およびその検出装置 |
| RS51346B (sr) * | 2007-10-25 | 2011-02-28 | Exelixis, Inc. | Jedinjenja tropana |
| ES2524576T3 (es) * | 2010-01-29 | 2014-12-10 | Nerviano Medical Sciences S.R.L. | Derivados de 6,7-dihidroimidazo[1,5-a]pirazin-8(5H)-ona como moduladores de proteína cinasa |
| CA2808629C (en) * | 2010-08-18 | 2020-06-16 | Del Mar Pharmaceuticals | Method of synthesis of substituted hexitols such as dianhydrogalactitol |
| CN102008541B (zh) * | 2010-10-08 | 2012-07-04 | 广西中医学院 | 无糖型复方扶芳藤制剂中3种主要活性成分的同时检测方法 |
| CN104428664B (zh) * | 2012-02-27 | 2018-09-21 | 德玛医药 | 用于分析和测定在卫康醇中杂质的改良分析方法 |
| BE1020835A5 (nl) * | 2012-03-20 | 2014-06-03 | Maes Francis N V | Werkwijze voor het vervaardigen van een plantenextract, i.h.b. uit desmodium. |
-
2014
- 2014-11-18 KR KR1020167016274A patent/KR20160108315A/ko not_active Withdrawn
- 2014-11-18 MX MX2016006457A patent/MX2016006457A/es unknown
- 2014-11-18 CA CA2931088A patent/CA2931088A1/en not_active Abandoned
- 2014-11-18 CN CN201480073454.XA patent/CN107529337B/zh not_active Expired - Fee Related
- 2014-11-18 AU AU2014348232A patent/AU2014348232A1/en not_active Abandoned
- 2014-11-18 EP EP14862051.1A patent/EP3071555A4/en not_active Withdrawn
- 2014-11-18 WO PCT/US2014/066087 patent/WO2015074025A1/en not_active Ceased
- 2014-11-18 JP JP2016554543A patent/JP2016538574A/ja active Pending
-
2016
- 2016-05-18 CL CL2016001197A patent/CL2016001197A1/es unknown
- 2016-05-18 IL IL245713A patent/IL245713A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016538574A (ja) | 2016-12-08 |
| CA2931088A1 (en) | 2015-05-21 |
| CL2016001197A1 (es) | 2017-06-30 |
| IL245713A0 (en) | 2016-08-02 |
| CN107529337A (zh) | 2017-12-29 |
| WO2015074025A9 (en) | 2015-12-17 |
| EP3071555A1 (en) | 2016-09-28 |
| WO2015074025A1 (en) | 2015-05-21 |
| CN107529337B (zh) | 2021-11-16 |
| EP3071555A4 (en) | 2017-05-31 |
| KR20160108315A (ko) | 2016-09-19 |
| AU2014348232A1 (en) | 2016-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2016006457A (es) | Analisis de cromatografia liquida de alto rendimiento (hplc) de impurezas en dianhidrogalactitol. | |
| MX2014010312A (es) | Metodos analiticos mejorados para analizar y determinar impurezas en dianhidrogalactitol. | |
| MX2017015229A (es) | Metodos para la cuantificacion espectrometrica de masas de analitos extraidos de un dispositivo de micromuestreo. | |
| Tomšíková et al. | High-sensitivity analysis of female-steroid hormones in environmental samples | |
| Yin et al. | Current state-of-the-art of nontargeted metabolomics based on liquid chromatography–mass spectrometry with special emphasis in clinical applications | |
| Qi et al. | Derivatization for liquid chromatography-mass spectrometry | |
| WO2012092281A3 (en) | Quantitation of insulin by mass spectrometry | |
| GB2519906A (en) | Methods and systems for detecting biological components | |
| GB2521579A (en) | Mass spectrometer, system comprising the same, and methods for determining isotopic anatomy of compounds | |
| EP4273523A3 (en) | Plasma-based optical emission method for detecting impurities in a gas | |
| MX380577B (es) | Detector de entrada y método de muestreo. | |
| Jiang et al. | Determination of trace level of perchlorate in Antarctic snow and ice by ion chromatography coupled with tandem mass spectrometry using an automated sample on-line preconcentration method | |
| WO2013026026A3 (en) | Shift correction for spectral analysis | |
| SG10201909836UA (en) | Apparatus and method for detecting trace metals with electrically conductive diamond electrodes | |
| SA115360693B1 (ar) | طريقة للكشف عن التلوث ببيركلورات وتحديد كميته | |
| GB2513805A (en) | Methods for quantifying polypeptides using mass spectrometry | |
| WO2014140570A3 (en) | Eluate analysis and collection | |
| MX379918B (es) | Metodos para analisis y resolucion de preparaciones de dianhidrogalactitol y derivados o analogos del mismo. | |
| BR112016000231A8 (pt) | métodos para identificações de condições de separação com cromatografia de troca de íons e para análises de composições de polipeptídeos | |
| WO2011088459A3 (en) | Continuous flow mobility classifier interface with mass spectrometer | |
| WO2013093582A3 (en) | Method and system for quantitative and qualitative analysis using mass spectrometry | |
| EA202090477A1 (ru) | Способ количественного определения содержания органической кислоты в сырой нефти | |
| EP4239329A3 (en) | Method and apparatus | |
| JP2016001137A5 (cg-RX-API-DMAC7.html) | ||
| Fouillen et al. | The lipid world concept of plant lipidomics |