IL245713A0 - Hplc analysis of impurities in dianhydrogalactitol - Google Patents

Hplc analysis of impurities in dianhydrogalactitol

Info

Publication number
IL245713A0
IL245713A0 IL245713A IL24571316A IL245713A0 IL 245713 A0 IL245713 A0 IL 245713A0 IL 245713 A IL245713 A IL 245713A IL 24571316 A IL24571316 A IL 24571316A IL 245713 A0 IL245713 A0 IL 245713A0
Authority
IL
Israel
Prior art keywords
dianhydrogalactitol
impurities
hplc analysis
hplc
analysis
Prior art date
Application number
IL245713A
Other languages
Hebrew (he)
Inventor
Lu Xiaoyun
Tso-Ping Li Mike
Original Assignee
Del Mar Pharmaceuticals
Lu Xiaoyun
Tso-Ping Li Mike
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/083,135 external-priority patent/US9029164B2/en
Application filed by Del Mar Pharmaceuticals, Lu Xiaoyun, Tso-Ping Li Mike filed Critical Del Mar Pharmaceuticals
Publication of IL245713A0 publication Critical patent/IL245713A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes
    • C07D301/02Synthesis of the oxirane ring
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/74Optical detectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/84Preparation of the fraction to be distributed
    • G01N2030/8447Nebulising, aerosol formation or ionisation
    • G01N2030/8494Desolvation chambers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8872Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample impurities

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
IL245713A 2013-11-18 2016-05-18 Hplc analysis of impurities in dianhydrogalactitol IL245713A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/083,135 US9029164B2 (en) 2012-02-27 2013-11-18 Analytical methods for analyzing and determining impurities in dianhydrogalactitol
PCT/US2014/066087 WO2015074025A1 (en) 2013-11-18 2014-11-18 Hplc analysis of impurities in dianhydrogalactitol

Publications (1)

Publication Number Publication Date
IL245713A0 true IL245713A0 (en) 2016-08-02

Family

ID=53058168

Family Applications (1)

Application Number Title Priority Date Filing Date
IL245713A IL245713A0 (en) 2013-11-18 2016-05-18 Hplc analysis of impurities in dianhydrogalactitol

Country Status (10)

Country Link
EP (1) EP3071555A4 (en)
JP (1) JP2016538574A (en)
KR (1) KR20160108315A (en)
CN (1) CN107529337B (en)
AU (1) AU2014348232A1 (en)
CA (1) CA2931088A1 (en)
CL (1) CL2016001197A1 (en)
IL (1) IL245713A0 (en)
MX (1) MX2016006457A (en)
WO (1) WO2015074025A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106397360A (en) * 2015-07-29 2017-02-15 广西梧州制药(集团)股份有限公司 Applications of tert-butanol in freeze drying process of dianhydrodulcitol or composition thereof
MX2018006425A (en) 2015-11-25 2018-11-09 Del Mar Pharmaceuticals Bc Ltd Methods for analysis and resolution of preparations of dianhydrogalactitol and derivatives or analogs thereof.
CN105445407B (en) * 2015-12-29 2017-04-19 成都普思生物科技股份有限公司 Detection method for fatty acid and vitamin E in idesia
JP6954644B2 (en) 2016-04-04 2021-10-27 国立大学法人三重大学 Method for producing unsaturated uronic acid monosaccharide using alginate lyase and the enzyme
KR102270026B1 (en) * 2020-01-31 2021-06-28 현대약품 주식회사 Quality evaluation method of (3S)-3-(4-(3-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)benzyloxy)phenyl)hex-4-ynoic acid
CN114113352A (en) * 2020-08-28 2022-03-01 深圳波顿香料有限公司 Method for measuring lactone sophorose ester content in fermentation liquor

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04297868A (en) * 1991-03-27 1992-10-21 Tonen Corp Analysis on oligo saccharide
JPH09229920A (en) * 1996-02-26 1997-09-05 Kao Corp Method for treating gradient liquid chromatography eluant
US6060525A (en) * 1996-03-01 2000-05-09 Dionix Corporation Removal of borate in chromatography
WO2000042225A1 (en) * 1999-01-14 2000-07-20 Board Of Supervisors Of Louisiana State Universityand Agricultural And Mechanical College Process for the separation of sugars
US20060148732A1 (en) * 2000-11-17 2006-07-06 Gutterman Jordan U Inhibition of NF-kappaB by triterpene compositions
JP2004294384A (en) * 2003-03-28 2004-10-21 National Agriculture & Bio-Oriented Research Organization Method of measuring 1-deoxynojirimycin
CA2819769C (en) * 2003-07-18 2016-06-28 Oakwood Laboratories, L.L.C. Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions
CA2567528A1 (en) * 2004-05-20 2005-12-01 Chiron S.R.L. Analysis of liquid chromatography eluates
JP2008076340A (en) * 2006-09-25 2008-04-03 Toppan Printing Co Ltd Highly sensitive detection method, and detector therefor
BRPI0818893B8 (en) * 2007-10-25 2021-05-25 Exelixis Inc tropane compounds, their pharmaceutical compositions, their uses and in vitro method of inhibiting hsp90 in a cell
WO2011092120A1 (en) * 2010-01-29 2011-08-04 Nerviano Medical Sciences S.R.L. 6,7- dihydroimidazo [1,5-a] pyrazin-8 (5h) - one derivatives as protein kinase modulators
SG188235A1 (en) * 2010-08-18 2013-04-30 Del Mar Pharmaceuticals Method of synthesis of substituted hexitols such as dianhydrogalactitol
CN102008541B (en) * 2010-10-08 2012-07-04 广西中医学院 Method for simultaneously detecting three main active ingredients in sugar-free type compound wintercreeper preparation
MX2014010312A (en) * 2012-02-27 2015-04-14 Del Mar Pharmaceuticals Improved analytical methods for analyzing and determining impurities in dianhydrogalactitol.
BE1020835A5 (en) * 2012-03-20 2014-06-03 Maes Francis N V METHOD FOR MANUFACTURING A PLANT EXTRACT, I.H.B. FROM DESMODIUM.

Also Published As

Publication number Publication date
KR20160108315A (en) 2016-09-19
AU2014348232A1 (en) 2016-06-30
WO2015074025A9 (en) 2015-12-17
CL2016001197A1 (en) 2017-06-30
MX2016006457A (en) 2017-01-06
EP3071555A1 (en) 2016-09-28
CA2931088A1 (en) 2015-05-21
CN107529337A (en) 2017-12-29
EP3071555A4 (en) 2017-05-31
WO2015074025A1 (en) 2015-05-21
CN107529337B (en) 2021-11-16
JP2016538574A (en) 2016-12-08

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