SG11201603115YA - Conjugates of somatostatin and its analogs - Google Patents

Conjugates of somatostatin and its analogs

Info

Publication number
SG11201603115YA
SG11201603115YA SG11201603115YA SG11201603115YA SG11201603115YA SG 11201603115Y A SG11201603115Y A SG 11201603115YA SG 11201603115Y A SG11201603115Y A SG 11201603115YA SG 11201603115Y A SG11201603115Y A SG 11201603115YA SG 11201603115Y A SG11201603115Y A SG 11201603115YA
Authority
SG
Singapore
Prior art keywords
somatostatin
conjugates
analogs
Prior art date
Application number
SG11201603115YA
Inventor
Eric L Schneider
Brian Hearn
Gary Ashley
Daniel V Santi
Original Assignee
Prolynx Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prolynx Llc filed Critical Prolynx Llc
Publication of SG11201603115YA publication Critical patent/SG11201603115YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6903Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SG11201603115YA 2013-10-22 2014-10-22 Conjugates of somatostatin and its analogs SG11201603115YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361894226P 2013-10-22 2013-10-22
PCT/US2014/061844 WO2015061503A1 (en) 2013-10-22 2014-10-22 Conjugates of somatostatin and its analogs

Publications (1)

Publication Number Publication Date
SG11201603115YA true SG11201603115YA (en) 2016-05-30

Family

ID=52993525

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201603115YA SG11201603115YA (en) 2013-10-22 2014-10-22 Conjugates of somatostatin and its analogs
SG10201803370XA SG10201803370XA (en) 2013-10-22 2014-10-22 Conjugates of somatostatin and its analogs

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201803370XA SG10201803370XA (en) 2013-10-22 2014-10-22 Conjugates of somatostatin and its analogs

Country Status (10)

Country Link
US (2) US10086049B2 (en)
EP (1) EP3060230A4 (en)
JP (1) JP2016534064A (en)
KR (1) KR20160075665A (en)
CN (1) CN106232131A (en)
AU (1) AU2014340095A1 (en)
CA (1) CA2928407A1 (en)
MX (1) MX2016005285A (en)
SG (2) SG11201603115YA (en)
WO (1) WO2015061503A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3555280A4 (en) * 2016-12-19 2020-09-09 The Regents of The University of California Dual-enzyme responsive peptides
JOP20190245A1 (en) 2017-04-20 2019-10-15 Novartis Ag Sustained release delivery systems comprising traceless linkers
EP3630189A4 (en) * 2017-05-24 2021-06-23 The Board of Regents of The University of Texas System Linkers for antibody drug conjugates
CA3075670C (en) * 2017-09-19 2022-05-31 Immunwork Inc. Pharmaceutical constructs with enhanced binding affinity with albumin
TW202027794A (en) 2018-10-03 2020-08-01 瑞士商諾華公司 Sustained delivery of angiopoetin-like 3 polypeptides
WO2021067458A1 (en) * 2019-09-30 2021-04-08 Beijing Xuanyi Pharmasciences Co., Ltd. Protein-macromolecule conjugates and methods of use thereof
US20230098031A1 (en) * 2019-12-11 2023-03-30 The General Hospital Corporation Methods for cell imaging
CN114409736B (en) * 2022-01-28 2023-09-15 中国科学院精密测量科学与技术创新研究院 Phasing arrangement medium based on amphiphilic oligopeptide and preparation method and application thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214792B1 (en) * 1996-04-12 2001-04-10 David Lew Simon Method for treating acute and severe diarrhea
US6706289B2 (en) 2000-10-31 2004-03-16 Pr Pharmaceuticals, Inc. Methods and compositions for enhanced delivery of bioactive molecules
US7452868B2 (en) 2005-03-11 2008-11-18 Indevus Pharmaceuticals, Inc. Controlled release formulations of octreotide
GB0711656D0 (en) 2007-06-15 2007-07-25 Camurus Ab Formulations
JP5536053B2 (en) 2008-06-25 2014-07-02 エンド ファーマスーティカルズ ソリューションズ インコーポレイテッド. Octreotide implant with release agent
CN102076331B (en) 2008-06-26 2013-12-18 普罗林科斯有限责任公司 Prodrugs and drug-macromolecule conjugates having controlled drug release rates
US8640315B1 (en) 2009-10-28 2014-02-04 Robert E. Nikkel Rotating adapter assembly
CN102711728B (en) * 2010-01-13 2016-01-20 益普生制药股份有限公司 For delaying the preparation method of the pharmaceutical composition discharging somatostatin analogue
WO2011140376A1 (en) 2010-05-05 2011-11-10 Prolynx Llc Controlled drug release from dendrimers
JP5977229B2 (en) 2010-05-05 2016-08-24 プロリンクス リミテッド ライアビリティ カンパニー Sustained release from macromolecular conjugates
JP5964815B2 (en) * 2010-05-05 2016-08-03 プロリンクス リミテッド ライアビリティ カンパニー Controlled release drug from solid carrier
SG11201400444VA (en) * 2011-09-07 2014-04-28 Prolynx Llc Hydrogels with biodegradable crosslinking
BR112014013693B1 (en) 2011-12-05 2023-01-31 Camurus Ab PREFORMULATION, AND, USE OF A PREFORMULATION

Also Published As

Publication number Publication date
US20180296648A1 (en) 2018-10-18
CA2928407A1 (en) 2015-04-30
CN106232131A (en) 2016-12-14
US10086049B2 (en) 2018-10-02
KR20160075665A (en) 2016-06-29
US20160271227A1 (en) 2016-09-22
JP2016534064A (en) 2016-11-04
US10413594B2 (en) 2019-09-17
AU2014340095A1 (en) 2016-05-26
EP3060230A4 (en) 2017-06-14
WO2015061503A1 (en) 2015-04-30
EP3060230A1 (en) 2016-08-31
SG10201803370XA (en) 2018-06-28
MX2016005285A (en) 2016-10-28

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