CL2016001197A1 - Hplc analysis of impurities in dianhydrogalactitol - Google Patents

Hplc analysis of impurities in dianhydrogalactitol

Info

Publication number
CL2016001197A1
CL2016001197A1 CL2016001197A CL2016001197A CL2016001197A1 CL 2016001197 A1 CL2016001197 A1 CL 2016001197A1 CL 2016001197 A CL2016001197 A CL 2016001197A CL 2016001197 A CL2016001197 A CL 2016001197A CL 2016001197 A1 CL2016001197 A1 CL 2016001197A1
Authority
CL
Chile
Prior art keywords
dianhydrogalactitol
impurities
hplc analysis
hplc
analysis
Prior art date
Application number
CL2016001197A
Other languages
Spanish (es)
Inventor
Xiaoyun Lu
Mike Tso-Ping Li
Original Assignee
Del Mar Pharmaceuticals
Xiaoyun Lu
Mike Tso-Ping Li
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/083,135 external-priority patent/US9029164B2/en
Application filed by Del Mar Pharmaceuticals, Xiaoyun Lu, Mike Tso-Ping Li filed Critical Del Mar Pharmaceuticals
Publication of CL2016001197A1 publication Critical patent/CL2016001197A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/74—Optical detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G01N2030/8447—Nebulising, aerosol formation or ionisation
    • G01N2030/8494—Desolvation chambers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8872—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample impurities

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CL2016001197A 2013-11-18 2016-05-18 Hplc analysis of impurities in dianhydrogalactitol CL2016001197A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14/083,135 US9029164B2 (en) 2012-02-27 2013-11-18 Analytical methods for analyzing and determining impurities in dianhydrogalactitol

Publications (1)

Publication Number Publication Date
CL2016001197A1 true CL2016001197A1 (en) 2017-06-30

Family

ID=53058168

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016001197A CL2016001197A1 (en) 2013-11-18 2016-05-18 Hplc analysis of impurities in dianhydrogalactitol

Country Status (10)

Country Link
EP (1) EP3071555A4 (en)
JP (1) JP2016538574A (en)
KR (1) KR20160108315A (en)
CN (1) CN107529337B (en)
AU (1) AU2014348232A1 (en)
CA (1) CA2931088A1 (en)
CL (1) CL2016001197A1 (en)
IL (1) IL245713A0 (en)
MX (1) MX2016006457A (en)
WO (1) WO2015074025A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106397360A (en) * 2015-07-29 2017-02-15 广西梧州制药（集团）股份有限公司 Application of tert-butyl alcohol in freeze drying process of dianhydrogalactitol or composition thereof
WO2017091588A1 (en) * 2015-11-25 2017-06-01 Delmar Pharmaceuticals, Inc. Methods for analysis and resolution of preparations of dianhydrogalactitol and derivatives or analogs thereof
CN105445407B (en) * 2015-12-29 2017-04-19 成都普思生物科技股份有限公司 Detection method for fatty acid and vitamin E in idesia
WO2017175694A1 (en) * 2016-04-04 2017-10-12 国立大学法人三重大学 Alginate lyase and method using enzyme for producing unsaturated uronic acid monosaccharide
KR102270026B1 (en) * 2020-01-31 2021-06-28 현대약품 주식회사 Quality evaluation method of (3S)-3-(4-(3-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)benzyloxy)phenyl)hex-4-ynoic acid
CN114113352A (en) * 2020-08-28 2022-03-01 深圳波顿香料有限公司 Method for measuring lactone sophorose ester content in fermentation liquor

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04297868A (en) * 1991-03-27 1992-10-21 Tonen Corp Analysis on oligo saccharide
JPH09229920A (en) * 1996-02-26 1997-09-05 Kao Corp Method for treating gradient liquid chromatography eluant
US6060525A (en) * 1996-03-01 2000-05-09 Dionix Corporation Removal of borate in chromatography
CA2359337C (en) * 1999-01-14 2005-09-13 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Process for the separation of sugars
US20060148732A1 (en) * 2000-11-17 2006-07-06 Gutterman Jordan U Inhibition of NF-kappaB by triterpene compositions
JP2004294384A (en) * 2003-03-28 2004-10-21 National Agriculture & Bio-Oriented Research Organization Method of measuring 1-deoxynojirimycin
ES2600554T3 (en) * 2003-07-18 2017-02-09 Oakwood Laboratories L.L.C. Prevention of polymer molecular weight reduction, impurity formation and gelation in polymeric compositions
RU2380700C2 (en) * 2004-05-20 2010-01-27 Чирон С.Р.Л. Analysis of eluates obtained from anion-exchange chromatography
JP2008076340A (en) * 2006-09-25 2008-04-03 Toppan Printing Co Ltd Highly sensitive detection method, and detector therefor
DE602008000754D1 (en) * 2007-10-25 2010-04-15 Exelixis Inc TROPANVERBINDUNGEN
EP2528918B1 (en) * 2010-01-29 2014-09-10 Nerviano Medical Sciences S.r.l. 6,7-dihydroimidazo[1,5-a]pyrazin-8(5h)-one derivatives as protein kinase modulators
EP2606020B1 (en) * 2010-08-18 2018-12-26 Del Mar Pharmaceuticals Method of synthesis of substituted hexitols such as dianhydrogalactitol
CN102008541B (en) * 2010-10-08 2012-07-04 广西中医学院 Method for simultaneously detecting three main active ingredients in sugar-free type compound wintercreeper preparation
MX2014010312A (en) * 2012-02-27 2015-04-14 Del Mar Pharmaceuticals Improved analytical methods for analyzing and determining impurities in dianhydrogalactitol.
BE1020835A5 (en) * 2012-03-20 2014-06-03 Maes Francis N V METHOD FOR MANUFACTURING A PLANT EXTRACT, I.H.B. FROM DESMODIUM.

Also Published As

Publication number Publication date
EP3071555A4 (en) 2017-05-31
EP3071555A1 (en) 2016-09-28
WO2015074025A1 (en) 2015-05-21
KR20160108315A (en) 2016-09-19
MX2016006457A (en) 2017-01-06
JP2016538574A (en) 2016-12-08
CA2931088A1 (en) 2015-05-21
IL245713A0 (en) 2016-08-02
AU2014348232A1 (en) 2016-06-30
CN107529337B (en) 2021-11-16
WO2015074025A9 (en) 2015-12-17
CN107529337A (en) 2017-12-29

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