MX2012009863A - Nanoparticulas para encapsulacion de compuestos, su preparacion y usos. - Google Patents
Nanoparticulas para encapsulacion de compuestos, su preparacion y usos.Info
- Publication number
- MX2012009863A MX2012009863A MX2012009863A MX2012009863A MX2012009863A MX 2012009863 A MX2012009863 A MX 2012009863A MX 2012009863 A MX2012009863 A MX 2012009863A MX 2012009863 A MX2012009863 A MX 2012009863A MX 2012009863 A MX2012009863 A MX 2012009863A
- Authority
- MX
- Mexico
- Prior art keywords
- nanoparticles
- same
- encapsulation
- compounds
- preparation
- Prior art date
Links
- 239000002105 nanoparticle Substances 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000005538 encapsulation Methods 0.000 title 1
- 239000002184 metal Substances 0.000 abstract 3
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000005018 casein Substances 0.000 abstract 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 1
- 235000021240 caseins Nutrition 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/11—Encapsulated compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- General Preparation And Processing Of Foods (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Nanopartículas para encapsulación de compuestos, su preparación y usos - Las nanopartículas comprenden una matriz de caseína, un aminoácido básico y un metal seleccionado entre un metal divalente, un metal trivalente y sus combinaciones. Dichas nanopartículas pueden encapsular un compuesto biológicamente activo, hidrosoluble o liposoluble. De aplicación en los sectores alimentario, farmacéutico y cosmético y en el de la nanotecnología.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES201030286 | 2010-02-26 | ||
PCT/ES2011/070118 WO2011104410A1 (es) | 2010-02-26 | 2011-02-24 | Nanopartículas para encapsulación de compuestos, su preparación y usos |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2012009863A true MX2012009863A (es) | 2013-01-29 |
MX342700B MX342700B (es) | 2016-10-10 |
Family
ID=44263006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012009863A MX342700B (es) | 2010-02-26 | 2011-02-24 | Nanoparticulas para encapsulacion de compuestos, su preparacion y usos. |
Country Status (14)
Country | Link |
---|---|
US (1) | US10894006B2 (es) |
EP (1) | EP2540169B1 (es) |
JP (1) | JP5758919B2 (es) |
KR (1) | KR101782547B1 (es) |
AU (1) | AU2011219694B2 (es) |
BR (1) | BR112012021372B8 (es) |
CA (1) | CA2789518C (es) |
DK (1) | DK2540169T3 (es) |
ES (1) | ES2594929T3 (es) |
MX (1) | MX342700B (es) |
PL (1) | PL2540169T3 (es) |
PT (1) | PT2540169T (es) |
RU (1) | RU2552957C2 (es) |
WO (1) | WO2011104410A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6235779B2 (ja) * | 2012-03-28 | 2017-11-22 | 株式会社コーセー | 葉酸含有組成物及び葉酸の安定化方法 |
NZ713235A (en) * | 2013-03-15 | 2019-12-20 | Glanbia Nutritionals Ireland Ltd | Product and method for improving bioavailability of therapeutic compounds |
EP2856987A1 (en) | 2013-10-07 | 2015-04-08 | Absorbest AB | A wound dressing and a method for manufacturing a wound dressing |
KR101652459B1 (ko) * | 2015-11-30 | 2016-09-02 | 진효준 | 우주에서 음식물 가열 및 섭취하기 위한 장치 |
RU2626529C1 (ru) * | 2016-02-10 | 2017-07-28 | Александр Александрович Кролевец | Способ получения йогурта, обогащенного витамином Е |
RU2644228C2 (ru) * | 2016-03-18 | 2018-02-08 | Александр Александрович Кролевец | Способ получения кефира, обогащенного витамином D |
RU2645462C2 (ru) * | 2016-04-22 | 2018-02-21 | Александр Александрович Кролевец | Способ получения творога с наноструктурированным витамином D |
MX2020006361A (es) | 2017-12-19 | 2020-08-17 | Nanobiotix | Nanoparticulas para su uso en la potenciacion del rendimiento cerebral o en el tratamiento del estres. |
KR20200110321A (ko) | 2017-12-19 | 2020-09-23 | 나노비오띡스 | 신경 장애의 치료에서 사용하기 위한 나노입자 |
RU2688770C1 (ru) * | 2018-12-11 | 2019-05-22 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" | Способ приготовления белоксодержащего десертного желейного продукта |
RU2703798C1 (ru) * | 2019-05-07 | 2019-10-22 | Александр Александрович Кролевец | Способ производства мороженого с наноструктурированной фолиевой кислотой |
IN202041023813A (es) * | 2020-06-06 | 2020-08-07 | ||
IT202000030992A1 (it) * | 2020-12-16 | 2022-06-16 | Tech Scientific S R L | Sistema per il rilascio controllato di principi attivi |
WO2024100217A1 (fr) * | 2022-11-10 | 2024-05-16 | Université De Lorraine | Nanoclusters à base de zinc, leurs procédés d'obtention et leurs utilisations pour lutter contre les carences en zinc |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4146649A (en) | 1976-10-14 | 1979-03-27 | Faberge, Incorporated | Skin moisturizing composition containing a polyethoxy fatty alcohol and a polyethoxy glycoside |
CH660284A5 (de) | 1983-06-16 | 1987-04-15 | Farley Health Products | Saeuglingsnahrung. |
US5945409A (en) * | 1995-03-10 | 1999-08-31 | Wilson T. Crandall | Topical moisturizing composition and method |
US6190693B1 (en) | 1998-04-17 | 2001-02-20 | Ortho-Mcneil Pharamceutical, Inc. | Pharmaceutical methods of delivering folic acid |
DE19820302A1 (de) * | 1998-05-04 | 2000-02-24 | Basf Ag | Kern/Schale-Partikel, ihre Herstellung und Verwendung |
JP3503884B2 (ja) * | 2000-01-28 | 2004-03-08 | 花王株式会社 | 化粧料 |
JP2002068922A (ja) * | 2000-08-23 | 2002-03-08 | Nonogawa Shoji Kk | 液状乳化化粧料 |
DE10042833A1 (de) * | 2000-08-30 | 2002-03-14 | Basf Ag | Feste Zubereitungen mit einer Multi-Kern Struktur |
US7105176B2 (en) * | 2000-11-29 | 2006-09-12 | Basf Aktiengesellschaft | Production of solid preparations of water-soluble, sparingly water-soluble or water-insoluble active compounds |
RU2213493C2 (ru) | 2001-05-29 | 2003-10-10 | Устинова Александра Васильевна | Консервы на мясной основе для питания беременных и кормящих женщин |
RU2223672C2 (ru) | 2002-03-22 | 2004-02-20 | Государственное учреждение Всероссийский научно-исследовательский институт птицеперерабатывающей промышленности | Консервы из мяса птицы для питания женщин в период беременности |
KR20040053740A (ko) * | 2003-06-23 | 2004-06-24 | (주)오이넷 | 지하철용 광고 시스템 및 그 제어방법 |
CN1993060A (zh) * | 2004-08-19 | 2007-07-04 | 帝斯曼知识产权资产管理有限公司 | 可脂溶物质的新型组合物 |
JP2006115751A (ja) * | 2004-10-21 | 2006-05-11 | Kyushu Univ | 疎水性物質を吸着保持したナノサイズのタンパクミセル構造体の製造方法 |
JP2006182891A (ja) * | 2004-12-27 | 2006-07-13 | Nippon Shokuhin Kako Co Ltd | 単孔担持体澱粉およびその製造法 |
ES2302571B2 (es) | 2005-03-18 | 2009-03-16 | Universidad Complutense De Madrid | Procedimiento de obtencion de embutidos cocidos enriquecidos con acido folico. |
ES2348963T3 (es) | 2006-03-27 | 2010-12-17 | Nestec S.A. | Utilizacion cosmetica de micelas de proteinas de suero. |
WO2007114262A1 (ja) * | 2006-03-29 | 2007-10-11 | Fujifilm Corporation | カゼインナノ粒子 |
JP2009536151A (ja) * | 2006-03-30 | 2009-10-08 | 富士フイルム株式会社 | ナノ粒子 |
CA2649788A1 (en) | 2006-04-20 | 2007-11-01 | Technion Research And Development Foundation Ltd. | Casein micelles for nanoencapsulation of hydrophobic compounds |
DE102006061929A1 (de) * | 2006-12-20 | 2008-06-26 | Takata-Petri Ag | Optischer Lenkwinkelsensor zur Bestimmung des Absolutwertes des Lenkwinkels |
EP1941804A1 (de) | 2007-01-08 | 2008-07-09 | Rivella International AG | Getränk auf der Basis von Milchserum, Grüntee-Extrakt und nahrungsergänzenden Zusatzstoffen |
JP2008189784A (ja) * | 2007-02-02 | 2008-08-21 | Kyushu Univ | 刺激応答性タンパク質ナノ粒子 |
JP2009040722A (ja) | 2007-08-09 | 2009-02-26 | Fujifilm Corp | 複数のタンパク質からなるカゼインナノ粒子 |
WO2009101612A2 (en) * | 2008-02-11 | 2009-08-20 | Technion Research And Development Foundation Ltd. | Beta-casein assemblies for enrichment of food and beverages and methods of preparation thereof |
DE102008036576A1 (de) * | 2008-07-31 | 2010-02-04 | Gelita Ag | Partikel aus Kollagenmaterial und Verfahren zur Herstellung |
JP2010132609A (ja) * | 2008-12-05 | 2010-06-17 | Fujifilm Corp | カゼインナノ粒子 |
-
2011
- 2011-02-24 DK DK11719583.4T patent/DK2540169T3/en active
- 2011-02-24 WO PCT/ES2011/070118 patent/WO2011104410A1/es active Application Filing
- 2011-02-24 MX MX2012009863A patent/MX342700B/es active IP Right Grant
- 2011-02-24 EP EP11719583.4A patent/EP2540169B1/en active Active
- 2011-02-24 KR KR1020127025188A patent/KR101782547B1/ko active IP Right Grant
- 2011-02-24 PL PL11719583.4T patent/PL2540169T3/pl unknown
- 2011-02-24 CA CA2789518A patent/CA2789518C/en active Active
- 2011-02-24 JP JP2012554379A patent/JP5758919B2/ja active Active
- 2011-02-24 ES ES11719583.4T patent/ES2594929T3/es active Active
- 2011-02-24 US US13/581,111 patent/US10894006B2/en active Active
- 2011-02-24 BR BR112012021372A patent/BR112012021372B8/pt active IP Right Grant
- 2011-02-24 RU RU2012141088/13A patent/RU2552957C2/ru active
- 2011-02-24 PT PT117195834T patent/PT2540169T/pt unknown
- 2011-02-24 AU AU2011219694A patent/AU2011219694B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
DK2540169T3 (en) | 2016-10-03 |
US20130209530A1 (en) | 2013-08-15 |
BR112012021372B1 (pt) | 2021-04-06 |
JP2013520191A (ja) | 2013-06-06 |
KR20130045849A (ko) | 2013-05-06 |
WO2011104410A1 (es) | 2011-09-01 |
ES2594929T3 (es) | 2016-12-23 |
CA2789518A1 (en) | 2011-09-01 |
KR101782547B1 (ko) | 2017-09-27 |
EP2540169B1 (en) | 2016-07-06 |
RU2012141088A (ru) | 2014-04-27 |
US10894006B2 (en) | 2021-01-19 |
BR112012021372B8 (pt) | 2021-05-25 |
BR112012021372A2 (pt) | 2016-08-09 |
EP2540169A1 (en) | 2013-01-02 |
CN102869271A (zh) | 2013-01-09 |
RU2552957C2 (ru) | 2015-06-10 |
MX342700B (es) | 2016-10-10 |
JP5758919B2 (ja) | 2015-08-05 |
AU2011219694A1 (en) | 2012-09-27 |
CA2789518C (en) | 2018-09-11 |
PL2540169T3 (pl) | 2016-12-30 |
PT2540169T (pt) | 2016-10-11 |
AU2011219694B2 (en) | 2014-12-18 |
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