MX2010001219A - Composiciones de acido hialuronico ajustablemente reticuladas. - Google Patents

Composiciones de acido hialuronico ajustablemente reticuladas.

Info

Publication number
MX2010001219A
MX2010001219A MX2010001219A MX2010001219A MX2010001219A MX 2010001219 A MX2010001219 A MX 2010001219A MX 2010001219 A MX2010001219 A MX 2010001219A MX 2010001219 A MX2010001219 A MX 2010001219A MX 2010001219 A MX2010001219 A MX 2010001219A
Authority
MX
Mexico
Prior art keywords
hyaluronic acid
crosslinking agents
crosslinked hyaluronic
acid compositions
crosslinking
Prior art date
Application number
MX2010001219A
Other languages
English (en)
Inventor
Dimitrios Stroumpoulis
Ahmet Tezel
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of MX2010001219A publication Critical patent/MX2010001219A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Transplantation (AREA)
  • Polymers & Plastics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Resins (AREA)
  • Cosmetics (AREA)

Abstract

La presente invención se refiere a composiciones en gel de ácido hialurónico reticulado biocompatible, métodos para su elaboración y uso, y los reticuladores usados para elaborarlas. En un aspecto de la invención, se describe un agente de reticulación de polietilenglicol para reticular ácido hialuróriico, preferiblemente un multifuncional similar a un PEG Estrella de 4-brazós. En otro aspecto de la invención, se describen agentes de reticulación que comprenden más de dos grupos funcionales. Estos agentes de reticulación multifuncionales pueden ser usados en su propia forma para reticular ácido hialurónico, o pueden ser combinados con agentes de reticulación bifuncional en relaciones variantes para hacer ácido hialurónico de intensidad mecánica ajustable y dureza. La presente invención también describe composiciones de ácido hialurónico que han sido revestidas con polietilenglicol y métodos para su uso.
MX2010001219A 2007-07-30 2008-07-24 Composiciones de acido hialuronico ajustablemente reticuladas. MX2010001219A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95277007P 2007-07-30 2007-07-30
PCT/US2008/070985 WO2009018076A1 (en) 2007-07-30 2008-07-24 Tunably crosslinked hyaluronic acid compositions

Publications (1)

Publication Number Publication Date
MX2010001219A true MX2010001219A (es) 2010-03-01

Family

ID=39769477

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010001219A MX2010001219A (es) 2007-07-30 2008-07-24 Composiciones de acido hialuronico ajustablemente reticuladas.

Country Status (12)

Country Link
US (2) US8318695B2 (es)
EP (1) EP2178923A1 (es)
JP (2) JP5518709B2 (es)
KR (1) KR20100046038A (es)
CN (2) CN101790542B (es)
AU (1) AU2008282541B2 (es)
BR (1) BRPI0815045A2 (es)
CA (1) CA2695179A1 (es)
HK (1) HK1142917A1 (es)
MX (1) MX2010001219A (es)
NZ (2) NZ583031A (es)
WO (1) WO2009018076A1 (es)

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AU2008282541A1 (en) 2009-02-05
US20130023658A1 (en) 2013-01-24
EP2178923A1 (en) 2010-04-28
US8318695B2 (en) 2012-11-27
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JP2010535277A (ja) 2010-11-18
CN101790542A (zh) 2010-07-28
US20090036403A1 (en) 2009-02-05
HK1142917A1 (en) 2010-12-17
WO2009018076A1 (en) 2009-02-05
CA2695179A1 (en) 2009-02-05
JP5518709B2 (ja) 2014-06-11
NZ583031A (en) 2012-05-25
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JP2014194018A (ja) 2014-10-09
AU2008282541B2 (en) 2013-09-26

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