MX2007013595A - Compuestos heterociclicos fusionados y composiciones y usos de estos. - Google Patents

Info

Publication number

MX2007013595A

MX2007013595A MX2007013595A MX2007013595A MX2007013595A MX 2007013595 A MX2007013595 A MX 2007013595A MX 2007013595 A MX2007013595 A MX 2007013595A MX 2007013595 A MX2007013595 A MX 2007013595A MX 2007013595 A MX2007013595 A MX 2007013595A

Authority

MX

Mexico

Prior art keywords

substituted

unsubstituted

pyrimidin

tetrahydro

amine

Prior art date

2005-05-04

Links

• Espacenet
• Global Dossier
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• 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims description 3
• ZZRLTCJZOJCIHC-UHFFFAOYSA-N 7-cyclohexyl-1-(cyclohexylamino)-3-morpholin-4-yl-6,8-dihydro-5h-2,7-naphthyridine-4-carbonitrile Chemical compound N1=C(N2CCOCC2)C(C#N)=C2CCN(C3CCCCC3)CC2=C1NC1CCCCC1 ZZRLTCJZOJCIHC-UHFFFAOYSA-N 0.000 claims description 2
• MBPDMPQGMKKBDF-UHFFFAOYSA-N 7-cyclohexyl-1-(cyclohexylamino)-3-piperidin-1-yl-6,8-dihydro-5h-2,7-naphthyridine-4-carbonitrile Chemical compound N1=C(N2CCCCC2)C(C#N)=C2CCN(C3CCCCC3)CC2=C1NC1CCCCC1 MBPDMPQGMKKBDF-UHFFFAOYSA-N 0.000 claims description 2
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• YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical compound COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 claims 2
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• RLLPVAHGXHCWKJ-IEBWSBKVSA-N (3-phenoxyphenyl)methyl (1s,3s)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Chemical compound CC1(C)[C@H](C=C(Cl)Cl)[C@@H]1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 RLLPVAHGXHCWKJ-IEBWSBKVSA-N 0.000 claims 1
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• VOICQPYJFZIJSN-UHFFFAOYSA-N n-[(2,3-difluorophenyl)methyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound N1=CC(C)=CC=C1N1CC2=C(NCC=3C(=C(F)C=CC=3)F)N=CN=C2CC1 VOICQPYJFZIJSN-UHFFFAOYSA-N 0.000 claims 1
• WFTRPAANKZLHNU-UHFFFAOYSA-N n-[(2-chlorophenyl)methyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound N1=CC(C)=CC=C1N1CC2=C(NCC=3C(=CC=CC=3)Cl)N=CN=C2CC1 WFTRPAANKZLHNU-UHFFFAOYSA-N 0.000 claims 1
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• AGALZLPLRSSCSZ-UHFFFAOYSA-N n-[(3,4-difluorophenyl)methyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound N1=CC(C)=CC=C1N1CC2=C(NCC=3C=C(F)C(F)=CC=3)N=CN=C2CC1 AGALZLPLRSSCSZ-UHFFFAOYSA-N 0.000 claims 1
• ZFFRYTRFMCOESZ-UHFFFAOYSA-N n-[(3-chlorophenyl)methyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound N1=CC(C)=CC=C1N1CC2=C(NCC=3C=C(Cl)C=CC=3)N=CN=C2CC1 ZFFRYTRFMCOESZ-UHFFFAOYSA-N 0.000 claims 1
• JOFHBLXBUDVYEL-UHFFFAOYSA-N n-[(3-fluorophenyl)methyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound N1=CC(C)=CC=C1N1CC2=C(NCC=3C=C(F)C=CC=3)N=CN=C2CC1 JOFHBLXBUDVYEL-UHFFFAOYSA-N 0.000 claims 1
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• DLHPMQWXJJUYJE-UHFFFAOYSA-N n-[(4-chlorophenyl)methyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound N1=CC(C)=CC=C1N1CC2=C(NCC=3C=CC(Cl)=CC=3)N=CN=C2CC1 DLHPMQWXJJUYJE-UHFFFAOYSA-N 0.000 claims 1
• NALREZXCDIQRQU-UHFFFAOYSA-N n-[(4-fluoro-3-methylphenyl)methyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound N1=CC(C)=CC=C1N1CC2=C(NCC=3C=C(C)C(F)=CC=3)N=CN=C2CC1 NALREZXCDIQRQU-UHFFFAOYSA-N 0.000 claims 1
• CGMKVHOIAYZASS-UHFFFAOYSA-N n-[(4-methoxyphenyl)methyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound C1=CC(OC)=CC=C1CNC1=NC=NC2=C1CN(C=1N=CC(C)=CC=1)CC2 CGMKVHOIAYZASS-UHFFFAOYSA-N 0.000 claims 1
• SSYSQHUWGQTOJV-UHFFFAOYSA-N n-[(4-methylphenyl)methyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound C1=CC(C)=CC=C1CNC1=NC=NC2=C1CN(C=1N=CC(C)=CC=1)CC2 SSYSQHUWGQTOJV-UHFFFAOYSA-N 0.000 claims 1
• DUPYPBQTFOKCSC-UHFFFAOYSA-N n-[1-(4-fluorophenyl)ethyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound C=1C=C(F)C=CC=1C(C)NC(C=1C2)=NC=NC=1CCN2C1=CC=C(C)C=N1 DUPYPBQTFOKCSC-UHFFFAOYSA-N 0.000 claims 1
• ORRVRGHOSLMGBL-UHFFFAOYSA-N n-[2-(2-chlorophenyl)ethyl]-6-(5-methylpyridin-2-yl)-7,8-dihydro-5h-pyrido[4,3-d]pyrimidin-4-amine Chemical compound N1=CC(C)=CC=C1N1CC2=C(NCCC=3C(=CC=CC=3)Cl)N=CN=C2CC1 ORRVRGHOSLMGBL-UHFFFAOYSA-N 0.000 claims 1
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