MX2007010399A - Derivados de quinazolina en la forma de inhibidores de cinasa de tirosina. - Google Patents
Derivados de quinazolina en la forma de inhibidores de cinasa de tirosina.Info
- Publication number
- MX2007010399A MX2007010399A MX2007010399A MX2007010399A MX2007010399A MX 2007010399 A MX2007010399 A MX 2007010399A MX 2007010399 A MX2007010399 A MX 2007010399A MX 2007010399 A MX2007010399 A MX 2007010399A MX 2007010399 A MX2007010399 A MX 2007010399A
- Authority
- MX
- Mexico
- Prior art keywords
- formula
- pharmaceutically acceptable
- chloro
- acceptable salt
- hydrogen
- Prior art date
Links
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 abstract description 2
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- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 15
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0504018A GB0504018D0 (en) | 2005-02-26 | 2005-02-26 | Quinazoline derivatives |
| GB0506657A GB0506657D0 (en) | 2005-03-31 | 2005-03-31 | Quinazoline derivatives |
| GB0524001A GB0524001D0 (en) | 2005-11-25 | 2005-11-25 | Quinazoline derivatives |
| PCT/GB2006/000656 WO2006090163A1 (en) | 2005-02-26 | 2006-02-24 | Quinazoline derivatives as tyrosine kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007010399A true MX2007010399A (es) | 2007-09-25 |
Family
ID=36390222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007010399A MX2007010399A (es) | 2005-02-26 | 2006-02-24 | Derivados de quinazolina en la forma de inhibidores de cinasa de tirosina. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8735410B2 (https=) |
| EP (1) | EP1856095B1 (https=) |
| JP (1) | JP5054544B2 (https=) |
| KR (1) | KR20070107151A (https=) |
| AR (1) | AR055564A1 (https=) |
| AT (1) | ATE521603T1 (https=) |
| AU (1) | AU2006217738A1 (https=) |
| BR (1) | BRPI0607432A2 (https=) |
| CA (1) | CA2599210A1 (https=) |
| IL (1) | IL184798A0 (https=) |
| MX (1) | MX2007010399A (https=) |
| NO (1) | NO20073878L (https=) |
| TW (1) | TW200640904A (https=) |
| UY (1) | UY29398A1 (https=) |
| WO (1) | WO2006090163A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2305844T3 (es) | 2003-09-16 | 2008-11-01 | Astrazeneca Ab | Derivados de quinazolina como inhibidores de tirosina cinasa. |
| GB0326459D0 (en) | 2003-11-13 | 2003-12-17 | Astrazeneca Ab | Quinazoline derivatives |
| JP5032851B2 (ja) | 2004-02-03 | 2012-09-26 | アストラゼネカ アクチボラグ | キナゾリン誘導体 |
| CA2735875A1 (en) | 2008-09-03 | 2010-03-11 | Boehringer Ingelheim International Gmbh | Use of quinazoline derivatives for the treatment of viral diseases |
| KR20140096571A (ko) * | 2013-01-28 | 2014-08-06 | 한미약품 주식회사 | 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법 |
| CN103288759B (zh) * | 2013-05-16 | 2015-05-20 | 苏州明锐医药科技有限公司 | 达克米替尼的制备方法 |
| CA2974442A1 (en) * | 2015-02-03 | 2016-08-11 | Trillium Therapeutics Inc. | Novel fluorinated derivatives as egfr inhibitors useful for treating cancers |
| WO2019062637A1 (zh) * | 2017-09-28 | 2019-04-04 | 南京明德新药研发股份有限公司 | 喹啉衍生物及其作为酪氨酸激酶抑制剂的应用 |
| BR112021004527A2 (pt) | 2018-09-14 | 2021-06-08 | Spectrum Pharmaceuticals, Inc. | kits e métodos para tratamento contra câncer |
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-
2006
- 2006-02-24 MX MX2007010399A patent/MX2007010399A/es not_active Application Discontinuation
- 2006-02-24 KR KR1020077021853A patent/KR20070107151A/ko not_active Withdrawn
- 2006-02-24 WO PCT/GB2006/000656 patent/WO2006090163A1/en not_active Ceased
- 2006-02-24 TW TW095106212A patent/TW200640904A/zh unknown
- 2006-02-24 AR ARP060100689A patent/AR055564A1/es unknown
- 2006-02-24 AU AU2006217738A patent/AU2006217738A1/en not_active Abandoned
- 2006-02-24 UY UY29398A patent/UY29398A1/es unknown
- 2006-02-24 BR BRPI0607432-4A patent/BRPI0607432A2/pt not_active IP Right Cessation
- 2006-02-24 US US11/884,923 patent/US8735410B2/en not_active Expired - Fee Related
- 2006-02-24 EP EP06709888A patent/EP1856095B1/en not_active Expired - Lifetime
- 2006-02-24 AT AT06709888T patent/ATE521603T1/de not_active IP Right Cessation
- 2006-02-24 JP JP2007556662A patent/JP5054544B2/ja not_active Expired - Fee Related
- 2006-02-24 CA CA002599210A patent/CA2599210A1/en not_active Abandoned
-
2007
- 2007-07-23 IL IL184798A patent/IL184798A0/en unknown
- 2007-07-24 NO NO20073878A patent/NO20073878L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070107151A (ko) | 2007-11-06 |
| BRPI0607432A2 (pt) | 2009-09-01 |
| TW200640904A (en) | 2006-12-01 |
| US8735410B2 (en) | 2014-05-27 |
| CA2599210A1 (en) | 2006-08-31 |
| IL184798A0 (en) | 2007-12-03 |
| JP5054544B2 (ja) | 2012-10-24 |
| AR055564A1 (es) | 2007-08-22 |
| ATE521603T1 (de) | 2011-09-15 |
| AU2006217738A1 (en) | 2006-08-31 |
| EP1856095B1 (en) | 2011-08-24 |
| UY29398A1 (es) | 2006-10-02 |
| NO20073878L (no) | 2007-10-23 |
| WO2006090163A1 (en) | 2006-08-31 |
| US20110152297A1 (en) | 2011-06-23 |
| EP1856095A1 (en) | 2007-11-21 |
| JP2008531536A (ja) | 2008-08-14 |
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| FA | Abandonment or withdrawal |