ATE521603T1 - Chinazolinderivate als tyrosinkinaseinhibitoren - Google Patents

Chinazolinderivate als tyrosinkinaseinhibitoren

Info

Publication number
ATE521603T1
ATE521603T1 AT06709888T AT06709888T ATE521603T1 AT E521603 T1 ATE521603 T1 AT E521603T1 AT 06709888 T AT06709888 T AT 06709888T AT 06709888 T AT06709888 T AT 06709888T AT E521603 T1 ATE521603 T1 AT E521603T1
Authority
AT
Austria
Prior art keywords
tyrosine kinase
kinase inhibitors
quinazoline derivatives
quinazoline
derivatives
Prior art date
Application number
AT06709888T
Other languages
English (en)
Inventor
Christopher Thomas Halsall
Laurent Francois Andre Hennequin
Alleyn Thomas Plowright
Richard Storey
Kieran Lennon
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36390222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE521603(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0504018A external-priority patent/GB0504018D0/en
Priority claimed from GB0506657A external-priority patent/GB0506657D0/en
Priority claimed from GB0524001A external-priority patent/GB0524001D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE521603T1 publication Critical patent/ATE521603T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT06709888T 2005-02-26 2006-02-24 Chinazolinderivate als tyrosinkinaseinhibitoren ATE521603T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0504018A GB0504018D0 (en) 2005-02-26 2005-02-26 Quinazoline derivatives
GB0506657A GB0506657D0 (en) 2005-03-31 2005-03-31 Quinazoline derivatives
GB0524001A GB0524001D0 (en) 2005-11-25 2005-11-25 Quinazoline derivatives
PCT/GB2006/000656 WO2006090163A1 (en) 2005-02-26 2006-02-24 Quinazoline derivatives as tyrosine kinase inhibitors

Publications (1)

Publication Number Publication Date
ATE521603T1 true ATE521603T1 (de) 2011-09-15

Family

ID=36390222

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06709888T ATE521603T1 (de) 2005-02-26 2006-02-24 Chinazolinderivate als tyrosinkinaseinhibitoren

Country Status (15)

Country Link
US (1) US8735410B2 (de)
EP (1) EP1856095B1 (de)
JP (1) JP5054544B2 (de)
KR (1) KR20070107151A (de)
AR (1) AR055564A1 (de)
AT (1) ATE521603T1 (de)
AU (1) AU2006217738A1 (de)
BR (1) BRPI0607432A2 (de)
CA (1) CA2599210A1 (de)
IL (1) IL184798A0 (de)
MX (1) MX2007010399A (de)
NO (1) NO20073878L (de)
TW (1) TW200640904A (de)
UY (1) UY29398A1 (de)
WO (1) WO2006090163A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8629153B2 (en) 2008-09-03 2014-01-14 Boehringer Ingelheim International Gmbh Use of quinazoline derivatives for the treatment of viral diseases
KR20140096571A (ko) * 2013-01-28 2014-08-06 한미약품 주식회사 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법
CN103288759B (zh) * 2013-05-16 2015-05-20 苏州明锐医药科技有限公司 达克米替尼的制备方法
CA2974442A1 (en) * 2015-02-03 2016-08-11 Trillium Therapeutics Inc. Novel fluorinated derivatives as egfr inhibitors useful for treating cancers
WO2019062637A1 (zh) 2017-09-28 2019-04-04 南京明德新药研发股份有限公司 喹啉衍生物及其作为酪氨酸激酶抑制剂的应用
JP2022500456A (ja) * 2018-09-14 2022-01-04 ハンミ ファーマシューティカル カンパニー リミテッド キナゾリン化合物及びその塩酸塩の結晶形

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Also Published As

Publication number Publication date
IL184798A0 (en) 2007-12-03
US8735410B2 (en) 2014-05-27
NO20073878L (no) 2007-10-23
MX2007010399A (es) 2007-09-25
AR055564A1 (es) 2007-08-22
CA2599210A1 (en) 2006-08-31
AU2006217738A1 (en) 2006-08-31
EP1856095A1 (de) 2007-11-21
UY29398A1 (es) 2006-10-02
JP5054544B2 (ja) 2012-10-24
BRPI0607432A2 (pt) 2009-09-01
TW200640904A (en) 2006-12-01
US20110152297A1 (en) 2011-06-23
KR20070107151A (ko) 2007-11-06
EP1856095B1 (de) 2011-08-24
WO2006090163A1 (en) 2006-08-31
JP2008531536A (ja) 2008-08-14

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