MX2007009429A - Pirrolopirimidinas utiles como inhibidores de proteinas cinasas. - Google Patents

Pirrolopirimidinas utiles como inhibidores de proteinas cinasas.

Info

Publication number
MX2007009429A
MX2007009429A MX2007009429A MX2007009429A MX2007009429A MX 2007009429 A MX2007009429 A MX 2007009429A MX 2007009429 A MX2007009429 A MX 2007009429A MX 2007009429 A MX2007009429 A MX 2007009429A MX 2007009429 A MX2007009429 A MX 2007009429A
Authority
MX
Mexico
Prior art keywords
compound according
aliphatic
alkyl
optionally substituted
compound
Prior art date
Application number
MX2007009429A
Other languages
English (en)
Spanish (es)
Inventor
Tiansheng Wang
Francesco G Salituro
Mark W Ledeboer
Albert C Pierce
John P Duffy
David Messersmith
Guy W Bemis
Luc J Farmer
Jian Wang
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of MX2007009429A publication Critical patent/MX2007009429A/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
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    • A61P35/02Antineoplastic agents specific for leukemia
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
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  • Pain & Pain Management (AREA)
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  • Hospice & Palliative Care (AREA)
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MX2007009429A 2005-02-03 2006-02-02 Pirrolopirimidinas utiles como inhibidores de proteinas cinasas. MX2007009429A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64978105P 2005-02-03 2005-02-03
PCT/US2006/004019 WO2006096270A1 (en) 2005-02-03 2006-02-02 Pyrrolopyrimidines useful as inhibitors of protein kinase

Publications (1)

Publication Number Publication Date
MX2007009429A true MX2007009429A (es) 2008-03-18

Family

ID=36498734

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007009429A MX2007009429A (es) 2005-02-03 2006-02-02 Pirrolopirimidinas utiles como inhibidores de proteinas cinasas.

Country Status (16)

Country Link
US (2) US8633205B2 (cg-RX-API-DMAC7.html)
EP (1) EP1844050B1 (cg-RX-API-DMAC7.html)
JP (2) JP5227032B2 (cg-RX-API-DMAC7.html)
KR (1) KR20070104641A (cg-RX-API-DMAC7.html)
CN (1) CN101142218B (cg-RX-API-DMAC7.html)
AT (1) ATE420883T1 (cg-RX-API-DMAC7.html)
AU (1) AU2006221065A1 (cg-RX-API-DMAC7.html)
CA (1) CA2596830A1 (cg-RX-API-DMAC7.html)
DE (1) DE602006004844D1 (cg-RX-API-DMAC7.html)
ES (1) ES2320487T3 (cg-RX-API-DMAC7.html)
IL (1) IL184898A0 (cg-RX-API-DMAC7.html)
MX (1) MX2007009429A (cg-RX-API-DMAC7.html)
NO (1) NO20074431L (cg-RX-API-DMAC7.html)
RU (1) RU2434871C2 (cg-RX-API-DMAC7.html)
WO (1) WO2006096270A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200707342B (cg-RX-API-DMAC7.html)

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US7902187B2 (en) 2006-10-04 2011-03-08 Wyeth Llc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
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AU2007338574A1 (en) 2006-11-01 2008-07-03 Vertex Pharmaceuticals Incorporated Tricyclic heteroaryl compounds useful as inhibitors of Janus kinase
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KR20130066703A (ko) * 2008-02-06 2013-06-20 노파르티스 아게 피롤로[2,3­d]피리미딘 및 티로신 키나제 억제제로서 그의 용도
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US20110207754A1 (en) * 2010-02-18 2011-08-25 Incyte Corporation Cyclobutane and methylcyclobutane derivatives as janus kinase inhibitors
DK3354652T3 (da) 2010-03-10 2020-05-18 Incyte Holdings Corp Piperidin-4-yl azetidinderivativer som jak1-inhibitorer
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