MX2007008255A - Tioeteres de tripeptido y tetrapeptido. - Google Patents
Tioeteres de tripeptido y tetrapeptido.Info
- Publication number
- MX2007008255A MX2007008255A MX2007008255A MX2007008255A MX2007008255A MX 2007008255 A MX2007008255 A MX 2007008255A MX 2007008255 A MX2007008255 A MX 2007008255A MX 2007008255 A MX2007008255 A MX 2007008255A MX 2007008255 A MX2007008255 A MX 2007008255A
- Authority
- MX
- Mexico
- Prior art keywords
- tripeptide
- bone marrow
- tumor cells
- chemotherapeutic agents
- tetrapeptide
- Prior art date
Links
- 150000003568 thioethers Chemical class 0.000 title abstract 2
- 210000001185 bone marrow Anatomy 0.000 abstract 3
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 229940127089 cytotoxic agent Drugs 0.000 abstract 2
- 210000004881 tumor cell Anatomy 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 231100000433 cytotoxic Toxicity 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 230000003028 elevating effect Effects 0.000 abstract 1
- 230000011132 hemopoiesis Effects 0.000 abstract 1
- 230000000116 mitigating effect Effects 0.000 abstract 1
- 230000003039 myelosuppressive effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64193205P | 2005-01-06 | 2005-01-06 | |
| PCT/US2006/000219 WO2006074249A1 (en) | 2005-01-06 | 2006-01-04 | Tripeptide and tetrapeptide thioethers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007008255A true MX2007008255A (es) | 2007-09-11 |
Family
ID=36123437
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007008255A MX2007008255A (es) | 2005-01-06 | 2006-01-04 | Tioeteres de tripeptido y tetrapeptido. |
| MX2007008254A MX2007008254A (es) | 2005-01-06 | 2006-01-05 | Sulfonas de tripeptidos y tetrapeptidos. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007008254A MX2007008254A (es) | 2005-01-06 | 2006-01-05 | Sulfonas de tripeptidos y tetrapeptidos. |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US7129215B2 (https=) |
| EP (2) | EP1833978B1 (https=) |
| JP (2) | JP4903716B2 (https=) |
| KR (2) | KR101244609B1 (https=) |
| CN (2) | CN101090977B (https=) |
| AR (2) | AR051889A1 (https=) |
| AT (2) | ATE410520T1 (https=) |
| AU (2) | AU2006204022B2 (https=) |
| BR (2) | BRPI0606520A2 (https=) |
| CA (2) | CA2587284C (https=) |
| DE (2) | DE602006003064D1 (https=) |
| DK (2) | DK1833978T3 (https=) |
| EA (2) | EA200701398A1 (https=) |
| ES (2) | ES2314890T3 (https=) |
| HR (2) | HRP20090128T3 (https=) |
| IL (2) | IL182836A (https=) |
| MX (2) | MX2007008255A (https=) |
| NZ (2) | NZ555362A (https=) |
| PL (2) | PL1833978T3 (https=) |
| PT (2) | PT1833978E (https=) |
| SI (2) | SI1833978T1 (https=) |
| TW (2) | TWI317739B (https=) |
| WO (2) | WO2006074249A1 (https=) |
| ZA (2) | ZA200704487B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8198247B2 (en) | 2004-12-21 | 2012-06-12 | Telik, Inc. | Process for and intermediates in the preparation of canfosfamide and its salts |
| BRPI0606520A2 (pt) * | 2005-01-06 | 2009-06-30 | Telik Inc | tripeptìdeo e tetrapeptìdeo tioéteres |
| US20070154963A1 (en) * | 2005-12-30 | 2007-07-05 | Danying Cai | Method to determine whether a compound is a cellular GSTpi inhibitor |
| US20090221703A1 (en) | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
| US20090238763A1 (en) | 2006-07-09 | 2009-09-24 | Chongxi Yu | High penetration compositions and uses thereof |
| WO2008056207A1 (en) * | 2006-11-08 | 2008-05-15 | Chongxi Yu | Transdermal delivery systems of peptides and related compounds |
| AU2016213759B2 (en) * | 2006-11-08 | 2018-03-29 | Chongxi Yu | Transdermal delivery systems of peptides and related compounds |
| WO2008149181A1 (en) | 2007-06-04 | 2008-12-11 | Techfields Inc | Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses |
| WO2010065936A1 (en) | 2008-12-04 | 2010-06-10 | Chongxi Yu | High penetration compositions and their applications |
| DE102008060888A1 (de) | 2008-12-09 | 2010-06-10 | Evonik Stockhausen Gmbh | Verfahren zur Herstellung von Acrolein umfassend die Aufarbeitung einer Rohglycerin-Phase |
| EP2427475B1 (en) | 2009-05-08 | 2020-11-04 | Techfields Biochem Co., Ltd. | High penetration prodrug compositions of peptides and peptide-related compounds |
| CA2797458A1 (en) * | 2010-06-07 | 2011-12-15 | Telik, Inc. | Tablet formulation of ezatiostat |
| JP2013528214A (ja) | 2010-06-07 | 2013-07-08 | テリック，インコーポレイテッド | 結晶性エザチオスタット塩酸塩非溶媒和物ｄ型の調製 |
| US20130035389A1 (en) * | 2011-08-05 | 2013-02-07 | Telik, Inc. | Methods for treating myelodysplastic syndrome with ezatiostat |
| JP5970439B2 (ja) * | 2013-09-20 | 2016-08-17 | チョンシー ユー | ペプチド及び関連化合物の経皮送達システム |
| CN106146616A (zh) * | 2015-04-03 | 2016-11-23 | 浙江海正药业股份有限公司 | 环肽类化合物及其制备和用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599903A (en) | 1992-04-03 | 1997-02-04 | Terrapin Technologies, Inc. | Glutathione analogs and paralog panels comprising glutathione mimics |
| US5556942A (en) | 1991-04-29 | 1996-09-17 | Terrapin Technologies, Inc. | Glutathione S-transferase-activated compounds |
| US5786336A (en) * | 1991-04-29 | 1998-07-28 | Terrapin Technologies, Inc. | Target-selective protocols based on mimics |
| US5955432A (en) | 1992-04-03 | 1999-09-21 | Terrapin Technologies, Inc. | Metabolic effects of certain glutathione analogs |
| US5767086A (en) | 1992-04-03 | 1998-06-16 | Terrapin Technologies, Inc. | Bone marrow stimulation by certain glutathione analogs |
| CA2105492C (en) * | 1993-09-03 | 2000-02-01 | Lawrence M. Kauvar | Glutathione analogs and paralog panels comprising glutathione mimics |
| US5908919A (en) * | 1993-10-01 | 1999-06-01 | Terrapin Technologies | Urethane mediated, GST specific molecular release systems |
| JPH11507056A (ja) * | 1995-06-07 | 1999-06-22 | テラピン テクノロジーズ、インク． | グルタチオンアナログの代謝的効果 |
| AU4124697A (en) * | 1996-09-02 | 1998-03-26 | Manchester Metropolitan University, The | S-blocked glutathiones |
| TW576838B (en) * | 1998-04-16 | 2004-02-21 | Teijin Ltd | Glutathione derivatives and application form thereof |
| ATE286741T1 (de) | 1999-01-27 | 2005-01-15 | Telik Inc | Glutathioneanaloge enthaltende therapeutische zusammensetzungen |
| US7029695B2 (en) | 2001-07-10 | 2006-04-18 | Telik, Inc. | Therapeutic compositions containing glutathione analogs |
| TWI323662B (en) * | 2002-11-15 | 2010-04-21 | Telik Inc | Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy |
| BRPI0606520A2 (pt) * | 2005-01-06 | 2009-06-30 | Telik Inc | tripeptìdeo e tetrapeptìdeo tioéteres |
-
2006
- 2006-01-04 BR BRPI0606520-1A patent/BRPI0606520A2/pt not_active IP Right Cessation
- 2006-01-04 AT AT06717426T patent/ATE410520T1/de active
- 2006-01-04 HR HR20090128T patent/HRP20090128T3/xx unknown
- 2006-01-04 CN CN2006800014949A patent/CN101090977B/zh not_active Expired - Fee Related
- 2006-01-04 PL PL06717426T patent/PL1833978T3/pl unknown
- 2006-01-04 MX MX2007008255A patent/MX2007008255A/es active IP Right Grant
- 2006-01-04 DE DE602006003064T patent/DE602006003064D1/de not_active Expired - Lifetime
- 2006-01-04 TW TW095100278A patent/TWI317739B/zh not_active IP Right Cessation
- 2006-01-04 DK DK06717426T patent/DK1833978T3/da active
- 2006-01-04 WO PCT/US2006/000219 patent/WO2006074249A1/en not_active Ceased
- 2006-01-04 SI SI200630153T patent/SI1833978T1/sl unknown
- 2006-01-04 JP JP2007550441A patent/JP4903716B2/ja not_active Expired - Fee Related
- 2006-01-04 NZ NZ555362A patent/NZ555362A/en not_active IP Right Cessation
- 2006-01-04 KR KR1020077018022A patent/KR101244609B1/ko not_active Expired - Fee Related
- 2006-01-04 TW TW095100277A patent/TWI317738B/zh not_active IP Right Cessation
- 2006-01-04 US US11/325,846 patent/US7129215B2/en not_active Expired - Fee Related
- 2006-01-04 AU AU2006204022A patent/AU2006204022B2/en not_active Ceased
- 2006-01-04 EP EP06717426A patent/EP1833978B1/en not_active Expired - Lifetime
- 2006-01-04 PT PT06717426T patent/PT1833978E/pt unknown
- 2006-01-04 ES ES06717426T patent/ES2314890T3/es not_active Expired - Lifetime
- 2006-01-04 EA EA200701398A patent/EA200701398A1/ru unknown
- 2006-01-04 CA CA2587284A patent/CA2587284C/en not_active Expired - Fee Related
- 2006-01-05 BR BRPI0606396-9A patent/BRPI0606396A2/pt not_active IP Right Cessation
- 2006-01-05 DK DK06717699T patent/DK1833842T3/da active
- 2006-01-05 NZ NZ555361A patent/NZ555361A/en not_active IP Right Cessation
- 2006-01-05 US US11/326,975 patent/US7192918B2/en not_active Expired - Fee Related
- 2006-01-05 EA EA200701399A patent/EA200701399A1/ru unknown
- 2006-01-05 PT PT06717699T patent/PT1833842E/pt unknown
- 2006-01-05 AU AU2006203901A patent/AU2006203901B2/en not_active Ceased
- 2006-01-05 HR HR20090134T patent/HRP20090134T3/xx unknown
- 2006-01-05 KR KR1020077012531A patent/KR20070091611A/ko not_active Ceased
- 2006-01-05 ES ES06717699T patent/ES2314891T3/es not_active Expired - Lifetime
- 2006-01-05 WO PCT/US2006/000532 patent/WO2006074409A1/en not_active Ceased
- 2006-01-05 JP JP2007550515A patent/JP4903717B2/ja not_active Expired - Fee Related
- 2006-01-05 DE DE602006003063T patent/DE602006003063D1/de not_active Expired - Lifetime
- 2006-01-05 CN CNA2006800013664A patent/CN101080418A/zh active Pending
- 2006-01-05 SI SI200630154T patent/SI1833842T1/sl unknown
- 2006-01-05 PL PL06717699T patent/PL1833842T3/pl unknown
- 2006-01-05 AT AT06717699T patent/ATE410440T1/de active
- 2006-01-05 CA CA2587310A patent/CA2587310C/en not_active Expired - Fee Related
- 2006-01-05 EP EP06717699A patent/EP1833842B1/en not_active Expired - Lifetime
- 2006-01-05 AR ARP060100041A patent/AR051889A1/es not_active Application Discontinuation
- 2006-01-05 MX MX2007008254A patent/MX2007008254A/es active IP Right Grant
- 2006-01-05 AR ARP060100042A patent/AR051890A1/es not_active Application Discontinuation
-
2007
- 2007-04-26 IL IL182836A patent/IL182836A/en not_active IP Right Cessation
- 2007-05-10 IL IL183107A patent/IL183107A/en not_active IP Right Cessation
- 2007-05-20 ZA ZA200704487A patent/ZA200704487B/xx unknown
- 2007-05-30 ZA ZA200704488A patent/ZA200704488B/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |