PT1833978E - Tioéteres de tripeptídeo e tetrapeptídeo - Google Patents

Tioéteres de tripeptídeo e tetrapeptídeo Download PDF

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Publication number
PT1833978E
PT1833978E PT06717426T PT06717426T PT1833978E PT 1833978 E PT1833978 E PT 1833978E PT 06717426 T PT06717426 T PT 06717426T PT 06717426 T PT06717426 T PT 06717426T PT 1833978 E PT1833978 E PT 1833978E
Authority
PT
Portugal
Prior art keywords
tripeptide
tetrapeptide
thioethers
tetrapeptide thioethers
Prior art date
Application number
PT06717426T
Other languages
English (en)
Inventor
Steven R Schow
Natalia Aurrecoechea
Andrew B Kelson
Robert W Macsata
Louise Robinson
Anthony J Sanchez
Nicholas M Santiago
Reyna J Simon
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc filed Critical Telik Inc
Publication of PT1833978E publication Critical patent/PT1833978E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT06717426T 2005-01-06 2006-01-04 Tioéteres de tripeptídeo e tetrapeptídeo PT1833978E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64193205P 2005-01-06 2005-01-06

Publications (1)

Publication Number Publication Date
PT1833978E true PT1833978E (pt) 2008-12-02

Family

ID=36123437

Family Applications (2)

Application Number Title Priority Date Filing Date
PT06717426T PT1833978E (pt) 2005-01-06 2006-01-04 Tioéteres de tripeptídeo e tetrapeptídeo
PT06717699T PT1833842E (pt) 2005-01-06 2006-01-05 Sulfonas de tripéptidos e tetrapéptidos

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT06717699T PT1833842E (pt) 2005-01-06 2006-01-05 Sulfonas de tripéptidos e tetrapéptidos

Country Status (25)

Country Link
US (2) US7129215B2 (pt)
EP (2) EP1833978B1 (pt)
JP (2) JP4903716B2 (pt)
KR (2) KR101244609B1 (pt)
CN (2) CN101090977B (pt)
AR (2) AR051890A1 (pt)
AT (2) ATE410520T1 (pt)
AU (2) AU2006204022B2 (pt)
BR (2) BRPI0606520A2 (pt)
CA (2) CA2587284C (pt)
DE (2) DE602006003064D1 (pt)
DK (2) DK1833978T3 (pt)
EA (2) EA200701398A1 (pt)
ES (2) ES2314890T3 (pt)
HK (2) HK1106778A1 (pt)
HR (2) HRP20090128T3 (pt)
IL (2) IL182836A (pt)
MX (2) MX2007008255A (pt)
NZ (2) NZ555362A (pt)
PL (2) PL1833978T3 (pt)
PT (2) PT1833978E (pt)
SI (2) SI1833978T1 (pt)
TW (2) TWI317739B (pt)
WO (2) WO2006074249A1 (pt)
ZA (2) ZA200704487B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8198247B2 (en) * 2004-12-21 2012-06-12 Telik, Inc. Process for and intermediates in the preparation of canfosfamide and its salts
PT1833978E (pt) * 2005-01-06 2008-12-02 Telik Inc Tioéteres de tripeptídeo e tetrapeptídeo
US20070154963A1 (en) * 2005-12-30 2007-07-05 Danying Cai Method to determine whether a compound is a cellular GSTpi inhibitor
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
AU2006350707A1 (en) * 2006-11-08 2008-05-15 Chongxi Yu Transdermal delivery systems of peptides and related compounds
AU2016213759B2 (en) * 2006-11-08 2018-03-29 Chongxi Yu Transdermal delivery systems of peptides and related compounds
JP2010529101A (ja) 2007-06-04 2010-08-26 テックフィールズ インコーポレイテッド 非常に速い皮膚及び膜浸透速度を有するｎｓａｉａプロドラッグ及びその新規医薬使用
CN111808011B (zh) 2008-12-04 2024-02-27 泰飞尔生物医药(苏州)有限公司 高穿透性组合物及其应用
DE102008060888A1 (de) 2008-12-09 2010-06-10 Evonik Stockhausen Gmbh Verfahren zur Herstellung von Acrolein umfassend die Aufarbeitung einer Rohglycerin-Phase
TWI568447B (zh) 2009-05-08 2017-02-01 Techfields Biochem Co Ltd 具有快速透皮速度的多肽及多肽相關化合物的前藥組合物
CN102939300A (zh) 2010-06-07 2013-02-20 泰立克公司 无溶剂化晶体依泽替米贝盐酸盐d型的制备
JP2013528213A (ja) * 2010-06-07 2013-07-08 テリック，インコーポレイテッド エザチオスタットの錠剤製剤
US20130035389A1 (en) * 2011-08-05 2013-02-07 Telik, Inc. Methods for treating myelodysplastic syndrome with ezatiostat
JP5970439B2 (ja) * 2013-09-20 2016-08-17 チョンシー ユー ペプチド及び関連化合物の経皮送達システム
CN106146616A (zh) * 2015-04-03 2016-11-23 浙江海正药业股份有限公司 环肽类化合物及其制备和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599903A (en) 1992-04-03 1997-02-04 Terrapin Technologies, Inc. Glutathione analogs and paralog panels comprising glutathione mimics
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
US5556942A (en) 1991-04-29 1996-09-17 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds
US5955432A (en) 1992-04-03 1999-09-21 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
US5767086A (en) 1992-04-03 1998-06-16 Terrapin Technologies, Inc. Bone marrow stimulation by certain glutathione analogs
CA2105492C (en) 1993-09-03 2000-02-01 Lawrence M. Kauvar Glutathione analogs and paralog panels comprising glutathione mimics
US5908919A (en) * 1993-10-01 1999-06-01 Terrapin Technologies Urethane mediated, GST specific molecular release systems
AU715524B2 (en) * 1995-06-07 2000-02-03 Telik, Inc. Metabolic effects of certain glutathione analogs
WO1998009986A1 (en) 1996-09-02 1998-03-12 The Manchester Metropolitan University S-blocked glutathiones
EP1072608B1 (en) * 1998-04-16 2005-06-15 Teijin Limited Glutathione derivatives and dosage forms thereof
JP2002535359A (ja) 1999-01-27 2002-10-22 テリック，インコーポレイテッド グルタチオン類縁体を含有する治療用組成物
US7029695B2 (en) 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
PT1833978E (pt) 2005-01-06 2008-12-02 Telik Inc Tioéteres de tripeptídeo e tetrapeptídeo

Also Published As

Publication number Publication date
HRP20090128T3 (en) 2009-04-30
JP2008526880A (ja) 2008-07-24
KR20070104391A (ko) 2007-10-25
IL183107A0 (en) 2007-09-20
ZA200704488B (en) 2008-09-25
AR051890A1 (es) 2007-02-14
PT1833842E (pt) 2008-12-11
KR101244609B1 (ko) 2013-03-25
SI1833978T1 (sl) 2009-04-30
AU2006204022B2 (en) 2011-01-20
WO2006074409A1 (en) 2006-07-13
ATE410440T1 (de) 2008-10-15
MX2007008254A (es) 2007-09-11
TWI317738B (en) 2009-12-01
WO2006074409A9 (en) 2006-12-14
BRPI0606520A2 (pt) 2009-06-30
JP2008526859A (ja) 2008-07-24
AU2006204022A1 (en) 2006-07-13
DK1833978T3 (da) 2009-02-09
CA2587284C (en) 2014-03-25
CN101090977A (zh) 2007-12-19
TW200635948A (en) 2006-10-16
US20060148719A1 (en) 2006-07-06
US7129215B2 (en) 2006-10-31
TW200635949A (en) 2006-10-16
ES2314891T3 (es) 2009-03-16
MX2007008255A (es) 2007-09-11
NZ555362A (en) 2009-05-31
KR20070091611A (ko) 2007-09-11
EA200701398A1 (ru) 2007-12-28
JP4903717B2 (ja) 2012-03-28
SI1833842T1 (sl) 2009-04-30
IL182836A0 (en) 2007-08-19
NZ555361A (en) 2009-05-31
US7192918B2 (en) 2007-03-20
CN101080418A (zh) 2007-11-28
HK1106778A1 (en) 2008-03-20
ZA200704487B (en) 2008-09-25
EP1833978B1 (en) 2008-10-08
EP1833842B1 (en) 2008-10-08
CA2587284A1 (en) 2006-07-13
CA2587310A1 (en) 2006-07-13
HK1106796A1 (en) 2008-03-20
HRP20090134T3 (en) 2009-04-30
EP1833842A1 (en) 2007-09-19
AU2006203901A1 (en) 2006-07-13
PL1833842T3 (pl) 2009-04-30
AR051889A1 (es) 2007-02-14
WO2006074249A1 (en) 2006-07-13
IL182836A (en) 2010-11-30
EA200701399A1 (ru) 2008-02-28
EP1833978A1 (en) 2007-09-19
BRPI0606396A2 (pt) 2009-06-23
DE602006003064D1 (en) 2008-11-20
PL1833978T3 (pl) 2009-04-30
TWI317739B (en) 2009-12-01
CA2587310C (en) 2013-11-12
JP4903716B2 (ja) 2012-03-28
CN101090977B (zh) 2013-04-10
ES2314890T3 (es) 2009-03-16
DK1833842T3 (da) 2009-02-09
DE602006003063D1 (de) 2008-11-20
US20060160749A1 (en) 2006-07-20
ATE410520T1 (de) 2008-10-15
IL183107A (en) 2010-11-30
AU2006203901B2 (en) 2011-06-02

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