ATE410520T1 - Tripeptid- und tetrapeptid-thioether - Google Patents

Tripeptid- und tetrapeptid-thioether

Info

Publication number
ATE410520T1
ATE410520T1 AT06717426T AT06717426T ATE410520T1 AT E410520 T1 ATE410520 T1 AT E410520T1 AT 06717426 T AT06717426 T AT 06717426T AT 06717426 T AT06717426 T AT 06717426T AT E410520 T1 ATE410520 T1 AT E410520T1
Authority
AT
Austria
Prior art keywords
tetrapeptide
tripeptide
thioether
tetrapeptide thioether
Prior art date
Application number
AT06717426T
Other languages
English (en)
Inventor
Natalia Aurrecoechea
Andrew Kelson
Robert Macsata
Louise Robinson
Anthony Sanchez
Nicholas Santiago
Steven Schow
Reyna Simon
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc filed Critical Telik Inc
Application granted granted Critical
Publication of ATE410520T1 publication Critical patent/ATE410520T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT06717426T 2005-01-06 2006-01-04 Tripeptid- und tetrapeptid-thioether ATE410520T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64193205P 2005-01-06 2005-01-06

Publications (1)

Publication Number Publication Date
ATE410520T1 true ATE410520T1 (de) 2008-10-15

Family

ID=36123437

Family Applications (2)

Application Number Title Priority Date Filing Date
AT06717426T ATE410520T1 (de) 2005-01-06 2006-01-04 Tripeptid- und tetrapeptid-thioether
AT06717699T ATE410440T1 (de) 2005-01-06 2006-01-05 Tripeptid- und tetrapeptidsulfone

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06717699T ATE410440T1 (de) 2005-01-06 2006-01-05 Tripeptid- und tetrapeptidsulfone

Country Status (25)

Country Link
US (2) US7129215B2 (de)
EP (2) EP1833978B1 (de)
JP (2) JP4903716B2 (de)
KR (2) KR101244609B1 (de)
CN (2) CN101090977B (de)
AR (2) AR051890A1 (de)
AT (2) ATE410520T1 (de)
AU (2) AU2006204022B2 (de)
BR (2) BRPI0606520A2 (de)
CA (2) CA2587284C (de)
DE (2) DE602006003064D1 (de)
DK (2) DK1833978T3 (de)
EA (2) EA200701398A1 (de)
ES (2) ES2314890T3 (de)
HK (2) HK1106778A1 (de)
HR (2) HRP20090128T3 (de)
IL (2) IL182836A (de)
MX (2) MX2007008255A (de)
NZ (2) NZ555362A (de)
PL (2) PL1833978T3 (de)
PT (2) PT1833978E (de)
SI (2) SI1833978T1 (de)
TW (2) TWI317739B (de)
WO (2) WO2006074249A1 (de)
ZA (2) ZA200704487B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8198247B2 (en) * 2004-12-21 2012-06-12 Telik, Inc. Process for and intermediates in the preparation of canfosfamide and its salts
KR101244609B1 (ko) * 2005-01-06 2013-03-25 텔리크 인코포레이티드 트리펩티드 및 테트라펩티드 티오에테르
US20070154963A1 (en) * 2005-12-30 2007-07-05 Danying Cai Method to determine whether a compound is a cellular GSTpi inhibitor
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
AU2016213759B2 (en) * 2006-11-08 2018-03-29 Chongxi Yu Transdermal delivery systems of peptides and related compounds
WO2008056207A1 (en) * 2006-11-08 2008-05-15 Chongxi Yu Transdermal delivery systems of peptides and related compounds
AU2007354632B2 (en) 2007-06-04 2014-06-26 Techfields Inc Pro-drugs of NSAIAs with very high skin and membranes penetration rates and their new medicinal uses
MX362949B (es) 2008-12-04 2019-02-27 Yu Chongxi Composiciones de alta penetracion y sus aplicaciones.
DE102008060888A1 (de) 2008-12-09 2010-06-10 Evonik Stockhausen Gmbh Verfahren zur Herstellung von Acrolein umfassend die Aufarbeitung einer Rohglycerin-Phase
KR101784528B1 (ko) 2009-05-08 2017-10-12 테크필즈 바이오켐 코., 엘티디. 펩티드 및 펩티드­관련 화합물의 고침투성 전구약물 조성물
CA2797458A1 (en) * 2010-06-07 2011-12-15 Telik, Inc. Tablet formulation of ezatiostat
EP2576592A1 (de) 2010-06-07 2013-04-10 Telik, Inc. Zubereitung von kristallinem ezatiostat- hydrochlorid-ansolvat form d
US20130035389A1 (en) * 2011-08-05 2013-02-07 Telik, Inc. Methods for treating myelodysplastic syndrome with ezatiostat
JP5970439B2 (ja) * 2013-09-20 2016-08-17 チョンシー ユー ペプチド及び関連化合物の経皮送達システム
CN106146616A (zh) * 2015-04-03 2016-11-23 浙江海正药业股份有限公司 环肽类化合物及其制备和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599903A (en) * 1992-04-03 1997-02-04 Terrapin Technologies, Inc. Glutathione analogs and paralog panels comprising glutathione mimics
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
US5556942A (en) * 1991-04-29 1996-09-17 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds
US5767086A (en) * 1992-04-03 1998-06-16 Terrapin Technologies, Inc. Bone marrow stimulation by certain glutathione analogs
US5955432A (en) * 1992-04-03 1999-09-21 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
CA2105492C (en) 1993-09-03 2000-02-01 Lawrence M. Kauvar Glutathione analogs and paralog panels comprising glutathione mimics
US5908919A (en) * 1993-10-01 1999-06-01 Terrapin Technologies Urethane mediated, GST specific molecular release systems
WO1996040205A1 (en) 1995-06-07 1996-12-19 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
GB2332676B (en) * 1996-09-02 2001-01-24 Univ Manchester Metropolitan S-Blocked glutathiones
EP1072608B1 (de) * 1998-04-16 2005-06-15 Teijin Limited Glutathionderivate und dazugehörige dosisformen
WO2000044366A2 (en) 1999-01-27 2000-08-03 Telik, Inc. Therapeutic compositions containing glutathione analogs
US7029695B2 (en) * 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
KR101244609B1 (ko) * 2005-01-06 2013-03-25 텔리크 인코포레이티드 트리펩티드 및 테트라펩티드 티오에테르

Also Published As

Publication number Publication date
US7192918B2 (en) 2007-03-20
CN101090977B (zh) 2013-04-10
JP4903716B2 (ja) 2012-03-28
AU2006203901B2 (en) 2011-06-02
ES2314890T3 (es) 2009-03-16
MX2007008254A (es) 2007-09-11
BRPI0606396A2 (pt) 2009-06-23
EP1833842A1 (de) 2007-09-19
PL1833842T3 (pl) 2009-04-30
WO2006074249A1 (en) 2006-07-13
HRP20090128T3 (en) 2009-04-30
EA200701399A1 (ru) 2008-02-28
DE602006003063D1 (de) 2008-11-20
DK1833842T3 (da) 2009-02-09
KR101244609B1 (ko) 2013-03-25
SI1833842T1 (sl) 2009-04-30
HK1106796A1 (en) 2008-03-20
ES2314891T3 (es) 2009-03-16
JP4903717B2 (ja) 2012-03-28
JP2008526859A (ja) 2008-07-24
AU2006203901A1 (en) 2006-07-13
CA2587310A1 (en) 2006-07-13
TW200635948A (en) 2006-10-16
US7129215B2 (en) 2006-10-31
KR20070091611A (ko) 2007-09-11
PT1833842E (pt) 2008-12-11
TWI317739B (en) 2009-12-01
WO2006074409A9 (en) 2006-12-14
US20060160749A1 (en) 2006-07-20
KR20070104391A (ko) 2007-10-25
PL1833978T3 (pl) 2009-04-30
IL182836A0 (en) 2007-08-19
ZA200704487B (en) 2008-09-25
PT1833978E (pt) 2008-12-02
CA2587284A1 (en) 2006-07-13
TWI317738B (en) 2009-12-01
ATE410440T1 (de) 2008-10-15
AR051889A1 (es) 2007-02-14
HK1106778A1 (en) 2008-03-20
BRPI0606520A2 (pt) 2009-06-30
ZA200704488B (en) 2008-09-25
DK1833978T3 (da) 2009-02-09
DE602006003064D1 (en) 2008-11-20
EA200701398A1 (ru) 2007-12-28
JP2008526880A (ja) 2008-07-24
EP1833978B1 (de) 2008-10-08
IL183107A0 (en) 2007-09-20
TW200635949A (en) 2006-10-16
EP1833842B1 (de) 2008-10-08
CA2587284C (en) 2014-03-25
NZ555361A (en) 2009-05-31
AU2006204022B2 (en) 2011-01-20
CN101090977A (zh) 2007-12-19
AU2006204022A1 (en) 2006-07-13
MX2007008255A (es) 2007-09-11
NZ555362A (en) 2009-05-31
IL182836A (en) 2010-11-30
IL183107A (en) 2010-11-30
EP1833978A1 (de) 2007-09-19
SI1833978T1 (sl) 2009-04-30
HRP20090134T3 (en) 2009-04-30
WO2006074409A1 (en) 2006-07-13
CA2587310C (en) 2013-11-12
AR051890A1 (es) 2007-02-14
US20060148719A1 (en) 2006-07-06
CN101080418A (zh) 2007-11-28

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