DK1833978T3 - Tripeptid- og tetrapeptidthioethere - Google Patents

Tripeptid- og tetrapeptidthioethere

Info

Publication number
DK1833978T3
DK1833978T3 DK06717426T DK06717426T DK1833978T3 DK 1833978 T3 DK1833978 T3 DK 1833978T3 DK 06717426 T DK06717426 T DK 06717426T DK 06717426 T DK06717426 T DK 06717426T DK 1833978 T3 DK1833978 T3 DK 1833978T3
Authority
DK
Denmark
Prior art keywords
tripeptide
tetrapeptide
thioethers
tetrapeptide thioethers
Prior art date
Application number
DK06717426T
Other languages
Danish (da)
English (en)
Inventor
Natalia Aurrecoechea
Andrew B Kelson
Robert W Macsata
Louise Robinson
Anthony J Sanchez
Nicholas M Santiago
Steven R Schow
Reyna J Simon
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc filed Critical Telik Inc
Application granted granted Critical
Publication of DK1833978T3 publication Critical patent/DK1833978T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK06717426T 2005-01-06 2006-01-04 Tripeptid- og tetrapeptidthioethere DK1833978T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64193205P 2005-01-06 2005-01-06
PCT/US2006/000219 WO2006074249A1 (en) 2005-01-06 2006-01-04 Tripeptide and tetrapeptide thioethers

Publications (1)

Publication Number Publication Date
DK1833978T3 true DK1833978T3 (da) 2009-02-09

Family

ID=36123437

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06717426T DK1833978T3 (da) 2005-01-06 2006-01-04 Tripeptid- og tetrapeptidthioethere
DK06717699T DK1833842T3 (da) 2005-01-06 2006-01-05 Tripeptid- og tetrapeptidsulfoner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK06717699T DK1833842T3 (da) 2005-01-06 2006-01-05 Tripeptid- og tetrapeptidsulfoner

Country Status (25)

Country Link
US (2) US7129215B2 (de)
EP (2) EP1833978B1 (de)
JP (2) JP4903716B2 (de)
KR (2) KR101244609B1 (de)
CN (2) CN101090977B (de)
AR (2) AR051890A1 (de)
AT (2) ATE410520T1 (de)
AU (2) AU2006204022B2 (de)
BR (2) BRPI0606520A2 (de)
CA (2) CA2587284C (de)
DE (2) DE602006003064D1 (de)
DK (2) DK1833978T3 (de)
EA (2) EA200701398A1 (de)
ES (2) ES2314890T3 (de)
HK (2) HK1106778A1 (de)
HR (2) HRP20090128T3 (de)
IL (2) IL182836A (de)
MX (2) MX2007008255A (de)
NZ (2) NZ555362A (de)
PL (2) PL1833978T3 (de)
PT (2) PT1833978E (de)
SI (2) SI1833978T1 (de)
TW (2) TWI317739B (de)
WO (2) WO2006074249A1 (de)
ZA (2) ZA200704487B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8198247B2 (en) * 2004-12-21 2012-06-12 Telik, Inc. Process for and intermediates in the preparation of canfosfamide and its salts
NZ555362A (en) * 2005-01-06 2009-05-31 Telik Inc Tripeptide and tetrapeptide thioethers
US20070154963A1 (en) * 2005-12-30 2007-07-05 Danying Cai Method to determine whether a compound is a cellular GSTpi inhibitor
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
WO2008056207A1 (en) * 2006-11-08 2008-05-15 Chongxi Yu Transdermal delivery systems of peptides and related compounds
AU2016213759B2 (en) * 2006-11-08 2018-03-29 Chongxi Yu Transdermal delivery systems of peptides and related compounds
KR20150058566A (ko) 2007-06-04 2015-05-28 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 ｎｓａｉａ 약물전구체 및 이들의 새로운 의약적 용도
KR20210123406A (ko) 2008-12-04 2021-10-13 충시 위 고투과력을 가진 조성물 및 이의 적용
DE102008060888A1 (de) 2008-12-09 2010-06-10 Evonik Stockhausen Gmbh Verfahren zur Herstellung von Acrolein umfassend die Aufarbeitung einer Rohglycerin-Phase
EP4067370A1 (de) 2009-05-08 2022-10-05 Chongxi Yu Prodrug-zusammensetzungen mit hoher durchdringung aus peptiden und peptidverbindungen
JP2013528213A (ja) * 2010-06-07 2013-07-08 テリック，インコーポレイテッド エザチオスタットの錠剤製剤
US8841476B2 (en) 2010-06-07 2014-09-23 Telik, Inc. Preparation of crystalline ezatiostat hydrochloride ansolvate form D
US20130035389A1 (en) * 2011-08-05 2013-02-07 Telik, Inc. Methods for treating myelodysplastic syndrome with ezatiostat
JP5970439B2 (ja) * 2013-09-20 2016-08-17 チョンシー ユー ペプチド及び関連化合物の経皮送達システム
CN106146616A (zh) * 2015-04-03 2016-11-23 浙江海正药业股份有限公司 环肽类化合物及其制备和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599903A (en) 1992-04-03 1997-02-04 Terrapin Technologies, Inc. Glutathione analogs and paralog panels comprising glutathione mimics
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
US5556942A (en) * 1991-04-29 1996-09-17 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds
US5767086A (en) 1992-04-03 1998-06-16 Terrapin Technologies, Inc. Bone marrow stimulation by certain glutathione analogs
US5955432A (en) 1992-04-03 1999-09-21 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
CA2105492C (en) 1993-09-03 2000-02-01 Lawrence M. Kauvar Glutathione analogs and paralog panels comprising glutathione mimics
US5908919A (en) * 1993-10-01 1999-06-01 Terrapin Technologies Urethane mediated, GST specific molecular release systems
DE69633722T2 (de) 1995-06-07 2005-11-03 TELIK, INC., Palo Alto Stoffwechseleffekt von bestimmten glutation analogen
AU4124697A (en) 1996-09-02 1998-03-26 Manchester Metropolitan University, The S-blocked glutathiones
TW576838B (en) 1998-04-16 2004-02-21 Teijin Ltd Glutathione derivatives and application form thereof
KR100750842B1 (ko) * 1999-01-27 2007-08-22 텔리크 인코포레이티드 글루타티온 유사체를 함유하는 치료 조성물
US7029695B2 (en) 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
NZ555362A (en) 2005-01-06 2009-05-31 Telik Inc Tripeptide and tetrapeptide thioethers

Also Published As

Publication number Publication date
US20060148719A1 (en) 2006-07-06
CN101080418A (zh) 2007-11-28
ZA200704488B (en) 2008-09-25
EP1833842B1 (de) 2008-10-08
KR101244609B1 (ko) 2013-03-25
JP2008526880A (ja) 2008-07-24
WO2006074409A1 (en) 2006-07-13
ATE410440T1 (de) 2008-10-15
TWI317739B (en) 2009-12-01
JP4903717B2 (ja) 2012-03-28
EA200701398A1 (ru) 2007-12-28
SI1833842T1 (sl) 2009-04-30
CA2587310C (en) 2013-11-12
JP2008526859A (ja) 2008-07-24
BRPI0606520A2 (pt) 2009-06-30
TWI317738B (en) 2009-12-01
ES2314891T3 (es) 2009-03-16
AU2006204022A1 (en) 2006-07-13
KR20070104391A (ko) 2007-10-25
HK1106796A1 (en) 2008-03-20
US7129215B2 (en) 2006-10-31
DK1833842T3 (da) 2009-02-09
AU2006203901A1 (en) 2006-07-13
TW200635948A (en) 2006-10-16
JP4903716B2 (ja) 2012-03-28
US20060160749A1 (en) 2006-07-20
IL182836A (en) 2010-11-30
AU2006203901B2 (en) 2011-06-02
ES2314890T3 (es) 2009-03-16
AR051889A1 (es) 2007-02-14
EP1833978B1 (de) 2008-10-08
IL183107A0 (en) 2007-09-20
PT1833842E (pt) 2008-12-11
EP1833842A1 (de) 2007-09-19
IL182836A0 (en) 2007-08-19
CA2587284A1 (en) 2006-07-13
HK1106778A1 (en) 2008-03-20
PL1833842T3 (pl) 2009-04-30
ATE410520T1 (de) 2008-10-15
DE602006003064D1 (en) 2008-11-20
CN101090977A (zh) 2007-12-19
PT1833978E (pt) 2008-12-02
BRPI0606396A2 (pt) 2009-06-23
HRP20090128T3 (en) 2009-04-30
EP1833978A1 (de) 2007-09-19
CA2587284C (en) 2014-03-25
MX2007008254A (es) 2007-09-11
WO2006074409A9 (en) 2006-12-14
DE602006003063D1 (de) 2008-11-20
TW200635949A (en) 2006-10-16
AR051890A1 (es) 2007-02-14
NZ555361A (en) 2009-05-31
KR20070091611A (ko) 2007-09-11
CA2587310A1 (en) 2006-07-13
US7192918B2 (en) 2007-03-20
ZA200704487B (en) 2008-09-25
MX2007008255A (es) 2007-09-11
NZ555362A (en) 2009-05-31
EA200701399A1 (ru) 2008-02-28
PL1833978T3 (pl) 2009-04-30
SI1833978T1 (sl) 2009-04-30
CN101090977B (zh) 2013-04-10
AU2006204022B2 (en) 2011-01-20
WO2006074249A1 (en) 2006-07-13
HRP20090134T3 (en) 2009-04-30
IL183107A (en) 2010-11-30

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