MX9702671A - Derivados metalocenicos de diariletileno, metodos de preparacion y composiciones farmaceuticas que contienen estos derivados. - Google Patents
Derivados metalocenicos de diariletileno, metodos de preparacion y composiciones farmaceuticas que contienen estos derivados.Info
- Publication number
- MX9702671A MX9702671A MX9702671A MX9702671A MX9702671A MX 9702671 A MX9702671 A MX 9702671A MX 9702671 A MX9702671 A MX 9702671A MX 9702671 A MX9702671 A MX 9702671A MX 9702671 A MX9702671 A MX 9702671A
- Authority
- MX
- Mexico
- Prior art keywords
- preparation
- methods
- pharmaceutical compositions
- compositions containing
- metallocenic
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229940011871 estrogen Drugs 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Compuestos de formula general (I), sus métodos de preparacion y composiciones farmacéuticas que los contienen. Los derivados de la invencion son convenientes para la preparacion de fármacos antitumorales para el uso, en particular, en el tratamiento de cánceres del pecho dependientes del estrogeno.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9412151A FR2725720B1 (fr) | 1994-10-12 | 1994-10-12 | Derives metalloceniques du diarylethylene, leurs procedes de preparation et compositions pharmaceutiques contenant lesdits derives |
| FR94/12151 | 1994-10-12 | ||
| FR9412151 | 1994-10-12 | ||
| PCT/FR1995/001323 WO1996011935A1 (fr) | 1994-10-12 | 1995-10-11 | Derives metalloceniques du diarylethylene, leurs procedes de preparation et compositions pharmaceutiques contenant lesdits derives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MXPA97002671A MXPA97002671A (es) | 1998-02-01 |
| MX9702671A true MX9702671A (es) | 1998-02-28 |
Family
ID=9467773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9702671A MX9702671A (es) | 1994-10-12 | 1995-10-11 | Derivados metalocenicos de diariletileno, metodos de preparacion y composiciones farmaceuticas que contienen estos derivados. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0804445B1 (es) |
| JP (1) | JPH10511641A (es) |
| KR (1) | KR100383847B1 (es) |
| AU (1) | AU685006B2 (es) |
| BR (1) | BR9509314A (es) |
| CA (1) | CA2202169A1 (es) |
| DE (1) | DE69515341T2 (es) |
| ES (1) | ES2145926T3 (es) |
| FR (1) | FR2725720B1 (es) |
| MX (1) | MX9702671A (es) |
| WO (1) | WO1996011935A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5863911A (en) * | 1994-10-12 | 1999-01-26 | Modelisation Et Mise Au Point De Molecules Medicinales | Diarylethylene metallocene derivatives, their processes of preparation and pharmaceutical compositions containing said derivatives |
| RU2132187C1 (ru) * | 1998-11-12 | 1999-06-27 | Антипов Борис Геннадиевич | Способ лечения заболеваний кожи и слизистых оболочек и магнитоактивное органическое соединение железа, используемое в нем |
| RU2131249C1 (ru) * | 1998-11-12 | 1999-06-10 | Антипов Борис Геннадиевич | Способ лечения онкологических заболеваний и иммунодефицитных состояний магнитоактивными органическими соединениями железа и иммуностимулирующее и противоопухолевое средство на их основе |
| US6800776B1 (en) * | 2003-09-23 | 2004-10-05 | Chung-Shan Institute Of Science & Technology | Method for the preparation of ferrocenyl substituted styrene |
| FR2872814A1 (fr) * | 2004-07-08 | 2006-01-13 | Gerard Jouen | Utilisation de derives organometalliques de polyphenols ethylene pour la preparation d'un medicament |
| DE102008004100A1 (de) | 2008-01-11 | 2009-07-16 | Westfälische Wilhelms-Universität Münster Körperschaft des öffentlichen Rechts | Metallocenophane als Cytostatika |
| CN109081856B (zh) * | 2018-09-29 | 2021-05-11 | 陕西科技大学 | 一种4-二茂铁基-6-芳基-2-氨基嘧啶类化合物及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2623486C2 (de) * | 1976-05-26 | 1982-12-30 | Hoechst Ag, 6000 Frankfurt | 3.5.5-Trimethylhexanoyl-ferrocen, Verfahren zu seiner Herstellung und pharmazeutische Präparate |
| DE3404443A1 (de) * | 1984-02-08 | 1985-08-08 | Hartmut Prof. Dr. 1000 Berlin Köpf | Metallicenium-salze und deren verwendung als cytostatica bei der krebsbekaempfung |
-
1994
- 1994-10-12 FR FR9412151A patent/FR2725720B1/fr not_active Expired - Fee Related
-
1995
- 1995-10-11 CA CA002202169A patent/CA2202169A1/fr not_active Abandoned
- 1995-10-11 MX MX9702671A patent/MX9702671A/es not_active Application Discontinuation
- 1995-10-11 DE DE69515341T patent/DE69515341T2/de not_active Expired - Fee Related
- 1995-10-11 ES ES95934197T patent/ES2145926T3/es not_active Expired - Lifetime
- 1995-10-11 WO PCT/FR1995/001323 patent/WO1996011935A1/fr not_active Ceased
- 1995-10-11 BR BR9509314A patent/BR9509314A/pt not_active IP Right Cessation
- 1995-10-11 JP JP8512980A patent/JPH10511641A/ja not_active Withdrawn
- 1995-10-11 EP EP95934197A patent/EP0804445B1/fr not_active Expired - Lifetime
- 1995-10-11 KR KR1019970702399A patent/KR100383847B1/ko not_active Expired - Fee Related
- 1995-10-11 AU AU36582/95A patent/AU685006B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| KR100383847B1 (ko) | 2003-07-22 |
| AU3658295A (en) | 1996-05-06 |
| ES2145926T3 (es) | 2000-07-16 |
| AU685006B2 (en) | 1998-01-08 |
| DE69515341D1 (de) | 2000-04-06 |
| EP0804445B1 (fr) | 2000-03-01 |
| FR2725720B1 (fr) | 1997-01-03 |
| WO1996011935A1 (fr) | 1996-04-25 |
| FR2725720A1 (fr) | 1996-04-19 |
| JPH10511641A (ja) | 1998-11-10 |
| EP0804445A1 (fr) | 1997-11-05 |
| BR9509314A (pt) | 1998-01-27 |
| DE69515341T2 (de) | 2000-10-19 |
| CA2202169A1 (fr) | 1996-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |