CA2235967A1 - Diarylethylene metallocene derivatives, their processes of preparation and pharmaceutical compositions containing said derivatives - Google Patents

Diarylethylene metallocene derivatives, their processes of preparation and pharmaceutical compositions containing said derivatives

Info

Publication number
CA2235967A1
CA2235967A1 CA002235967A CA2235967A CA2235967A1 CA 2235967 A1 CA2235967 A1 CA 2235967A1 CA 002235967 A CA002235967 A CA 002235967A CA 2235967 A CA2235967 A CA 2235967A CA 2235967 A1 CA2235967 A1 CA 2235967A1
Authority
CA
Canada
Prior art keywords
derivatives
preparation
processes
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002235967A
Other languages
French (fr)
Other versions
CA2235967C (en
Inventor
Siden Top
Gerard Jaouen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MODELISATION ET MISE AU POINT DE MOLECULES MEDICINALES - "4M"
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9412151A external-priority patent/FR2725720B1/en
Application filed by Individual filed Critical Individual
Publication of CA2235967A1 publication Critical patent/CA2235967A1/en
Application granted granted Critical
Publication of CA2235967C publication Critical patent/CA2235967C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Compounds of general Formula (I), (see fig I) wherein R3, R4, R5 and Z are as specifically defined, are provided herein, as well as their processes of preparation; and pharmaceutical compositions containing them. Thesederivatives are suitable for the preparation of antitumoral drugs for use, in particular, in the treatment of estrogen-dependent cancers.
CA002235967A 1994-10-12 1995-10-11 Diarylethylene metallocene derivatives, their processes of preparation and pharmaceutical compositions containing said derivatives Expired - Fee Related CA2235967C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR94/12151 1994-10-12
FR9412151A FR2725720B1 (en) 1994-10-12 1994-10-12 METALLOCENIC DIARYLETHYLENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES
CA002202169A CA2202169A1 (en) 1994-10-12 1995-10-11 Metallocenic diarylethylene derivatives, methods for their preparation and pharmaceutical compositions containing same

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002202169A Division CA2202169A1 (en) 1994-10-12 1995-10-11 Metallocenic diarylethylene derivatives, methods for their preparation and pharmaceutical compositions containing same

Publications (2)

Publication Number Publication Date
CA2235967A1 true CA2235967A1 (en) 1996-04-25
CA2235967C CA2235967C (en) 2001-12-18

Family

ID=25679228

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002235967A Expired - Fee Related CA2235967C (en) 1994-10-12 1995-10-11 Diarylethylene metallocene derivatives, their processes of preparation and pharmaceutical compositions containing said derivatives

Country Status (1)

Country Link
CA (1) CA2235967C (en)

Also Published As

Publication number Publication date
CA2235967C (en) 2001-12-18

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