MX2007007889A - Rescate del virus de influenza. - Google Patents
Rescate del virus de influenza.Info
- Publication number
- MX2007007889A MX2007007889A MX2007007889A MX2007007889A MX2007007889A MX 2007007889 A MX2007007889 A MX 2007007889A MX 2007007889 A MX2007007889 A MX 2007007889A MX 2007007889 A MX2007007889 A MX 2007007889A MX 2007007889 A MX2007007889 A MX 2007007889A
- Authority
- MX
- Mexico
- Prior art keywords
- influenza
- cell
- nucleic acid
- virus
- provides
- Prior art date
Links
- 241000712461 unidentified influenza virus Species 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 229960003971 influenza vaccine Drugs 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 235000013601 eggs Nutrition 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 241001515965 unidentified phage Species 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18651—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La invencion se refiere al campo de la produccion de vacunas contra la influenza; se han producido vacunas contra la influenza en huevos de gallina desarrollados con clones durante mas de 50 anos, pero recientemente ha habido esfuerzos considerables por desarrollar sistemas de cultivo de celulas para la produccion de vacunas; la invencion provee un acido nucleico que comprende un segmento de gen de la influenza y promotor de polimerasa de bacteriofago o una cadena complementaria de dicho acido nucleico y una celula que comprende tal acido nucleico capaz de producir un virus deseado de influenza; ademas, la invencion provee una composicion que comprende una celula o un material derivado de una celula de acuerdo con la invencion y un virus o un material derivado de una particula viral de acuerdo con la invencion.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04078527 | 2004-12-24 | ||
US64100305P | 2005-01-04 | 2005-01-04 | |
PCT/EP2005/057092 WO2006067211A1 (en) | 2004-12-24 | 2005-12-22 | Rescue of influenza virus |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2007007889A true MX2007007889A (es) | 2008-01-22 |
Family
ID=34928779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2007007889A MX2007007889A (es) | 2004-12-24 | 2005-12-22 | Rescate del virus de influenza. |
Country Status (20)
Country | Link |
---|---|
US (2) | US7959930B2 (es) |
EP (2) | EP2295542B1 (es) |
JP (2) | JP5620048B2 (es) |
KR (1) | KR101272487B1 (es) |
CN (1) | CN101379183B (es) |
AU (1) | AU2005318087B2 (es) |
BR (1) | BRPI0518568A2 (es) |
CA (1) | CA2592439C (es) |
DK (1) | DK1831357T3 (es) |
ES (1) | ES2395813T3 (es) |
HK (1) | HK1125674A1 (es) |
IL (1) | IL183888A (es) |
MX (1) | MX2007007889A (es) |
NO (1) | NO20073737L (es) |
NZ (1) | NZ556061A (es) |
PT (1) | PT1831357E (es) |
RU (2) | RU2435855C2 (es) |
TW (2) | TWI495724B (es) |
WO (1) | WO2006067211A1 (es) |
ZA (1) | ZA200705145B (es) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ527221A (en) | 2001-01-19 | 2006-09-29 | Vironovative B | A negative-sense single stranded RNA virus causing respiratory tract illness in susceptible mammals |
JP4553588B2 (ja) | 2002-02-21 | 2010-09-29 | メディミューン,エルエルシー | メタニューモウイルス(metapneumovirus)株と、ワクチン製剤でのおよび抗原配列発現用ベクターとしてのその使用 |
KR101272487B1 (ko) * | 2004-12-24 | 2013-06-07 | 에라스무스 유니버시티 메디컬 센터 로테르담 | 인플루엔자 바이러스의 구제 |
KR20080025171A (ko) | 2005-06-21 | 2008-03-19 | 메드이뮨 백신즈 인코포레이티드 | 이종성 프로테아제를 발현시키기 위한 방법 및 조성물 |
US7790434B2 (en) | 2005-06-21 | 2010-09-07 | Medimmune, Llc | Methods and compositions for expressing negative-sense viral RNA in canine cells |
US20110180430A1 (en) | 2005-11-04 | 2011-07-28 | Novartis Vaccines And Diagnostics Srl | Adjuvanted influenza vaccines including cytokine-inducing agents |
CA2628152C (en) | 2005-11-04 | 2016-02-02 | Novartis Vaccines And Diagnostics S.R.L. | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
EA014028B1 (ru) | 2005-11-04 | 2010-08-30 | Новартис Вэксинс Энд Диагностикс Срл | Эмульсии, содержащие свободное поверхностно-активное вещество в водной фазе в качестве адъюванта сплит вакцин против гриппа |
NZ568211A (en) | 2005-11-04 | 2011-11-25 | Novartis Vaccines & Diagnostic | Influenza vaccines including combinations of particulate adjuvants and immunopotentiators |
WO2007052155A2 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant |
DK1976559T6 (da) | 2006-01-27 | 2020-04-06 | Seqirus Uk Ltd | Influenzavacciner indeholdende hæmagglutinin og matrixproteiner |
EP2004226A1 (en) | 2006-03-24 | 2008-12-24 | Novartis Vaccines and Diagnostics GmbH & Co. KG | Storage of influenza vaccines without refrigeration |
US9254318B2 (en) | 2006-03-31 | 2016-02-09 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines |
US7682619B2 (en) | 2006-04-06 | 2010-03-23 | Cornell Research Foundation, Inc. | Canine influenza virus |
GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
CA2663196A1 (en) | 2006-09-11 | 2008-03-20 | Novartis Ag | Making influenza virus vaccines without using eggs |
NZ577405A (en) | 2006-12-06 | 2012-08-31 | Novartis Ag | Vaccines including antigen from four strains of influenza virus |
US9474798B2 (en) | 2007-06-18 | 2016-10-25 | Wisconsin Alumni Research Foundation | Influenza M2 protein mutant viruses as live influenza attenuated vaccines |
EA201070066A1 (ru) | 2007-06-27 | 2010-06-30 | Новартис Аг | Вакцины против гриппа с низким содержанием добавок |
GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
EP2268309B1 (en) | 2008-03-18 | 2015-01-21 | Novartis AG | Improvements in preparation of influenza virus vaccine antigens |
DK2396032T3 (en) | 2009-02-10 | 2016-12-19 | Seqirus Uk Ltd | Influenza vaccines with reduced amounts of squalene |
US20120093859A1 (en) | 2009-02-10 | 2012-04-19 | Novartis Ag | Influenza vaccine regimens for pandemic-associated strains |
JP2012517416A (ja) | 2009-02-10 | 2012-08-02 | ノバルティス アーゲー | 増加した量のh3抗原を含むインフルエンザワクチン |
DE102010018462A1 (de) | 2009-04-27 | 2011-04-07 | Novartis Ag | Impfstoffe zum Schutz gegen Influenza |
CA2769673A1 (en) | 2009-07-31 | 2011-02-03 | Novartis Ag | Reverse genetics systems |
JP2013507990A (ja) | 2009-10-26 | 2013-03-07 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | ベロ細胞において増強された複製を有する高力価の組換えインフルエンザウイルス |
US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
US20130183740A1 (en) * | 2010-06-02 | 2013-07-18 | Avir Green Hills Biotechnology Research Development Trade Ag | Novel method for generation of rna virus |
FR2962739B1 (fr) * | 2010-07-13 | 2014-01-31 | Univ Claude Bernard Lyon | Souches virales modifiees et procede pour ameliorer la production de semences vaccinales de virus influenza |
WO2013057715A1 (en) | 2011-10-20 | 2013-04-25 | Novartis Ag | Adjuvanted influenza b virus vaccines for pediatric priming |
GB201218195D0 (en) | 2012-10-10 | 2012-11-21 | Istituto Zooprofilattico Sperimentale Delle Venezie | Composition |
US10080794B2 (en) | 2013-03-15 | 2018-09-25 | University Of Maryland, College Park | Swine influenza viruses and constructs and uses thereof |
US9950057B2 (en) | 2013-07-15 | 2018-04-24 | Wisconsin Alumni Research Foundation (Warf) | High titer recombinant influenza viruses with enhanced replication in MDCK or vero cells or eggs |
WO2015196150A2 (en) | 2014-06-20 | 2015-12-23 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
US10633422B2 (en) | 2015-06-01 | 2020-04-28 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication by inhibiting microRNA lec7C binding to influenza viral cRNA and mRNA |
CA2986701A1 (en) | 2015-06-09 | 2016-12-15 | Sanofi Pasteur, Inc. | Methods of optimizing nucleotide sequences encoding engineered influenza proteins |
US11013795B2 (en) | 2015-06-26 | 2021-05-25 | Seqirus UK Limited | Antigenically matched influenza vaccines |
WO2017007839A1 (en) | 2015-07-06 | 2017-01-12 | Wisconsin Alumni Research Foundation (Warf) | Improved influenza virus replication for vaccine development |
HUE051783T2 (hu) | 2015-07-07 | 2021-03-29 | Seqirus Uk Ltd | Eljárás immunogén hemagglutinin mennyiségi meghatározására |
CN109477074B (zh) | 2016-02-19 | 2023-01-24 | 威斯康星旧生研究基金会 | 用于疫苗开发的改进的乙型流感病毒复制 |
JP2022527235A (ja) | 2019-01-23 | 2022-06-01 | 義裕 河岡 | インフルエンザウイルスにおける付加的遺伝子に遺伝的安定性を付与する突然変異 |
JP2022522112A (ja) | 2019-02-08 | 2022-04-14 | ウィスコンシン アルムニ リサーチ ファンデイション | ヒト化細胞系 |
US11390649B2 (en) | 2019-05-01 | 2022-07-19 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication for vaccine development |
JP2022551805A (ja) | 2019-08-27 | 2022-12-14 | ウィスコンシン アルムニ リサーチ ファンデイション | 卵内複製のための安定化されたhaを持つ組換えインフルエンザウイルス |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5854037A (en) * | 1989-08-28 | 1998-12-29 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand RNA virus expression systems and vaccines |
US5166057A (en) * | 1989-08-28 | 1992-11-24 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand rna virus expression-systems |
US6001634A (en) * | 1989-08-28 | 1999-12-14 | Palese; Peter | Recombinant negative strand RNA viruses |
US6887699B1 (en) * | 1990-05-22 | 2005-05-03 | Medimmune Vaccines, Inc. | Recombinant negative strand RNA virus expression systems and vaccines |
US6544785B1 (en) * | 1998-09-14 | 2003-04-08 | Mount Sinai School Of Medicine Of New York University | Helper-free rescue of recombinant negative strand RNA viruses |
US8715940B2 (en) * | 1999-04-06 | 2014-05-06 | Wisconsin Alumni Research Foundation | Method of making recombinant influenza virus |
ES2290024T3 (es) | 1999-04-06 | 2008-02-16 | Wisconsin Alumni Research Foundation | Virus de la gripe recombinantes para vacunas y terapia genica. |
ATE353370T1 (de) | 1999-07-14 | 2007-02-15 | Sinai School Medicine | In vitro-rekonstitution von segmentierten, negativstrang-rna-viren |
MXPA02001177A (es) * | 1999-08-02 | 2002-07-02 | Wyeth Corp | Recuperacion del virus de las paperas del acido desoxirribonucleico recombinante. |
US6764685B1 (en) * | 2000-03-21 | 2004-07-20 | Medimmune Vaccines, Inc. | Recombinant parainfluenza virus expression systems and vaccines |
BRPI0110607B8 (pt) * | 2000-04-28 | 2021-05-25 | St Jude Childrens Res Hospital | sistema baseado em plasmídeos, método para produzir um vírion de vírus com fita rna negativa, método para produzir um vírion orthomyxoviridae, método para produzir um vírion influenza, método para produzir um vírion influenzapatogênico, método para preparar uma vacina específica de vírus rna de fita negativa e método para gerar um vírus rna de fita negativa atenuado |
IL153005A0 (en) * | 2000-06-23 | 2003-06-24 | American Cyanamid Co | Nucleotide sequence of influenza a/udorn/72 (h3n2) genome |
JP4553588B2 (ja) * | 2002-02-21 | 2010-09-29 | メディミューン,エルエルシー | メタニューモウイルス(metapneumovirus)株と、ワクチン製剤でのおよび抗原配列発現用ベクターとしてのその使用 |
WO2003091401A2 (en) * | 2002-04-26 | 2003-11-06 | Medimmune Vaccines, Inc. | Multi plasmid system for the production of influenza virus |
US7037707B2 (en) * | 2003-09-04 | 2006-05-02 | St. Jude Children's Research Hospital | Method for generating influenza viruses and vaccines |
KR101272487B1 (ko) * | 2004-12-24 | 2013-06-07 | 에라스무스 유니버시티 메디컬 센터 로테르담 | 인플루엔자 바이러스의 구제 |
-
2005
- 2005-12-22 KR KR1020077017093A patent/KR101272487B1/ko not_active IP Right Cessation
- 2005-12-22 RU RU2007128336/10A patent/RU2435855C2/ru not_active IP Right Cessation
- 2005-12-22 JP JP2007547535A patent/JP5620048B2/ja not_active Expired - Fee Related
- 2005-12-22 CA CA2592439A patent/CA2592439C/en not_active Expired - Fee Related
- 2005-12-22 EP EP10182258A patent/EP2295542B1/en not_active Not-in-force
- 2005-12-22 NZ NZ556061A patent/NZ556061A/en not_active IP Right Cessation
- 2005-12-22 DK DK05825287.5T patent/DK1831357T3/da active
- 2005-12-22 CN CN2005800447512A patent/CN101379183B/zh not_active Expired - Fee Related
- 2005-12-22 AU AU2005318087A patent/AU2005318087B2/en not_active Ceased
- 2005-12-22 MX MX2007007889A patent/MX2007007889A/es active IP Right Grant
- 2005-12-22 WO PCT/EP2005/057092 patent/WO2006067211A1/en active Application Filing
- 2005-12-22 US US11/722,769 patent/US7959930B2/en not_active Expired - Fee Related
- 2005-12-22 BR BRPI0518568-8A patent/BRPI0518568A2/pt not_active IP Right Cessation
- 2005-12-22 ES ES05825287T patent/ES2395813T3/es active Active
- 2005-12-22 PT PT58252875T patent/PT1831357E/pt unknown
- 2005-12-22 EP EP05825287A patent/EP1831357B1/en active Active
- 2005-12-23 TW TW101113590A patent/TWI495724B/zh not_active IP Right Cessation
- 2005-12-23 TW TW094146438A patent/TWI402344B/zh not_active IP Right Cessation
-
2007
- 2007-06-13 IL IL183888A patent/IL183888A/en not_active IP Right Cessation
- 2007-06-21 ZA ZA200705145A patent/ZA200705145B/xx unknown
- 2007-07-18 NO NO20073737A patent/NO20073737L/no not_active Application Discontinuation
-
2009
- 2009-04-30 HK HK09104018.1A patent/HK1125674A1/xx not_active IP Right Cessation
-
2011
- 2011-04-15 US US13/088,120 patent/US20120156241A1/en not_active Abandoned
- 2011-05-31 RU RU2011122117/10A patent/RU2011122117A/ru not_active Application Discontinuation
-
2012
- 2012-03-22 JP JP2012065345A patent/JP5702321B2/ja not_active Expired - Fee Related
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HC | Change of company name or juridical status |