MX2007002616A - Muteinas de factor de crecimiento de fibroblasto 21. - Google Patents

Muteinas de factor de crecimiento de fibroblasto 21.

Info

Publication number
MX2007002616A
MX2007002616A MX2007002616A MX2007002616A MX2007002616A MX 2007002616 A MX2007002616 A MX 2007002616A MX 2007002616 A MX2007002616 A MX 2007002616A MX 2007002616 A MX2007002616 A MX 2007002616A MX 2007002616 A MX2007002616 A MX 2007002616A
Authority
MX
Mexico
Prior art keywords
muteins
growth factor
fibroblast growth
nucleic acid
disclosed
Prior art date
Application number
MX2007002616A
Other languages
English (en)
Spanish (es)
Inventor
Christopher Carl Frye
Radmila Micanovic
Lihua Huang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX2007002616A publication Critical patent/MX2007002616A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
MX2007002616A 2004-09-02 2005-07-26 Muteinas de factor de crecimiento de fibroblasto 21. MX2007002616A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60680504P 2004-09-02 2004-09-02
PCT/US2005/026398 WO2006028595A2 (en) 2004-09-02 2005-07-26 Muteins of fibroblast growth factor 21

Publications (1)

Publication Number Publication Date
MX2007002616A true MX2007002616A (es) 2007-05-16

Family

ID=36036790

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007002616A MX2007002616A (es) 2004-09-02 2005-07-26 Muteinas de factor de crecimiento de fibroblasto 21.

Country Status (21)

Country Link
US (1) US7582607B2 (https=)
EP (2) EP2161281A1 (https=)
JP (1) JP4809352B2 (https=)
KR (1) KR100854198B1 (https=)
CN (1) CN101010338B (https=)
AT (1) ATE444307T1 (https=)
AU (1) AU2005283025B2 (https=)
BR (1) BRPI0514790A (https=)
CA (1) CA2575753A1 (https=)
DE (1) DE602005016946D1 (https=)
DK (1) DK1789442T3 (https=)
EA (1) EA011390B1 (https=)
ES (1) ES2332057T3 (https=)
HR (1) HRP20090597T1 (https=)
IL (1) IL181573A0 (https=)
MX (1) MX2007002616A (https=)
NO (1) NO20071327L (https=)
PL (1) PL1789442T3 (https=)
PT (1) PT1789442E (https=)
SI (1) SI1789442T1 (https=)
WO (1) WO2006028595A2 (https=)

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US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
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US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US20110034373A1 (en) * 2007-08-03 2011-02-10 Eli Lilly And Company Use of an fgf-21 compound and a glp-1 compound for the treatment of obesity
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CA2739615C (en) * 2008-10-10 2017-12-05 Amgen Inc. Fgf21 mutants comprising polyethylene glycol and uses thereof
US9120871B2 (en) 2009-01-23 2015-09-01 Novo Nordisk A/S Process for preparing FGF21 with low degree of O-glycosylation
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WO2010129503A1 (en) * 2009-05-05 2010-11-11 Amgen Inc. Fgf21 mutants and uses thereof
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WO2011154349A2 (en) 2010-06-08 2011-12-15 Novo Nordisk A/S Fgf21 analogues and derivatives
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TWI593708B (zh) * 2011-09-26 2017-08-01 諾華公司 治療代謝病症之融合蛋白質
AR087973A1 (es) * 2011-10-04 2014-04-30 Lilly Co Eli Variantes del factor 21 del crecimiento de fibroblastos
BR112014014898A2 (pt) 2011-12-22 2020-10-27 Pfizer Inc. processo para purificar uma amostra de anticorpo h38c2, ou variante do mesmo, e composição compreendendo o referido h38c2
CN104203977A (zh) 2012-02-15 2014-12-10 诺和诺德A/S(股份有限公司) 结合肽聚糖识别蛋白1的抗体
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US9550830B2 (en) 2012-02-15 2017-01-24 Novo Nordisk A/S Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
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US9290557B2 (en) 2012-11-28 2016-03-22 Ngm Biopharmaceuticals, Inc. Compositions comprising variants and fusions of FGF19 polypeptides
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Also Published As

Publication number Publication date
AU2005283025B2 (en) 2011-06-30
US20080103096A1 (en) 2008-05-01
US7582607B2 (en) 2009-09-01
CN101010338B (zh) 2011-06-15
EA200700533A1 (ru) 2007-08-31
BRPI0514790A (pt) 2008-06-24
KR20070050454A (ko) 2007-05-15
CA2575753A1 (en) 2006-03-16
JP4809352B2 (ja) 2011-11-09
KR100854198B1 (ko) 2008-08-26
ATE444307T1 (de) 2009-10-15
SI1789442T1 (sl) 2010-01-29
EP1789442A2 (en) 2007-05-30
HRP20090597T1 (hr) 2009-12-31
PT1789442E (pt) 2009-11-11
IL181573A0 (en) 2007-07-04
DK1789442T3 (da) 2009-11-16
WO2006028595A2 (en) 2006-03-16
DE602005016946D1 (de) 2009-11-12
ES2332057T3 (es) 2010-01-25
CN101010338A (zh) 2007-08-01
JP2008511323A (ja) 2008-04-17
EA011390B1 (ru) 2009-02-27
AU2005283025A1 (en) 2006-03-16
WO2006028595A3 (en) 2007-01-18
NO20071327L (no) 2007-05-29
PL1789442T3 (pl) 2010-02-26
EP2161281A1 (en) 2010-03-10
EP1789442B1 (en) 2009-09-30

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