MXPA02002384A - Polipeptidos similares al factor de crecimiento de fibroblastos. - Google Patents

Polipeptidos similares al factor de crecimiento de fibroblastos.

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Publication number
MXPA02002384A
MXPA02002384A MXPA02002384A MXPA02002384A MXPA02002384A MX PA02002384 A MXPA02002384 A MX PA02002384A MX PA02002384 A MXPA02002384 A MX PA02002384A MX PA02002384 A MXPA02002384 A MX PA02002384A MX PA02002384 A MXPA02002384 A MX PA02002384A
Authority
MX
Mexico
Prior art keywords
polypeptides
growth factor
fibroblast growth
fgf
methods
Prior art date
Application number
MXPA02002384A
Other languages
English (en)
Inventor
Michael Danilenko Dimitry
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/391,861 external-priority patent/US7408047B1/en
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MXPA02002384A publication Critical patent/MXPA02002384A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/50—Fibroblast growth factors [FGF]

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  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
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Abstract

La presente invencion proporciona los novedosos polipeptidos similares al Factor de Crecimiento de Fibroblastos (similar a FGF) y las moleculas de acido nucleico que codifican los mismos. La invencion tambien proporciona los vectores, las celulas huesped, los anticuerpos y los metodos para producir los polipeptidos similares a FGF. Tambien se proporcionan los metodos para el diagnostico y tratamiento de enfermedades asociadas con los polipeptidos similares a FGF.
MXPA02002384A 1999-09-07 2000-09-05 Polipeptidos similares al factor de crecimiento de fibroblastos. MXPA02002384A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/391,861 US7408047B1 (en) 1999-09-07 1999-09-07 Fibroblast growth factor-like polypeptides
US09/644,052 US7459540B1 (en) 1999-09-07 2000-08-23 Fibroblast growth factor-like polypeptides
PCT/US2000/024373 WO2001018172A2 (en) 1999-09-07 2000-09-05 Fibroblast growth factor-like polypeptides

Publications (1)

Publication Number Publication Date
MXPA02002384A true MXPA02002384A (es) 2004-09-10

Family

ID=27013655

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02002384A MXPA02002384A (es) 1999-09-07 2000-09-05 Polipeptidos similares al factor de crecimiento de fibroblastos.

Country Status (13)

Country Link
US (10) US7459540B1 (es)
EP (4) EP2258722A3 (es)
JP (4) JP4793836B2 (es)
AT (1) ATE430197T1 (es)
AU (1) AU7350000A (es)
CA (1) CA2383774C (es)
CY (1) CY1109166T1 (es)
DE (1) DE60042122D1 (es)
DK (1) DK1218509T3 (es)
ES (1) ES2326407T3 (es)
MX (1) MXPA02002384A (es)
PT (1) PT1218509E (es)
WO (1) WO2001018172A2 (es)

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US7576190B2 (en) 2004-05-13 2009-08-18 Eli Lilly And Company FGF-21 fusion proteins
CN101031655A (zh) 2004-07-26 2007-09-05 陶氏环球技术公司 通过株工程改进蛋白表达的方法
EP2161281A1 (en) 2004-09-02 2010-03-10 Eli Lilly & Company Muteins of fibroblast growth factor 21
US7622445B2 (en) 2004-09-02 2009-11-24 Eli Lilly And Company Muteins of fibroblast growth factor 21
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JP2008528487A (ja) * 2005-01-21 2008-07-31 イーライ リリー アンド カンパニー 心臓血管疾患を治療する方法
JP2006246823A (ja) * 2005-03-11 2006-09-21 Kyoto Univ 造血因子としてのＦｇｆ２１の使用
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