DK1032668T3 - Fibroblast vækstfaktor 19 - Google Patents

Fibroblast vækstfaktor 19

Info

Publication number
DK1032668T3
DK1032668T3 DK98961795T DK98961795T DK1032668T3 DK 1032668 T3 DK1032668 T3 DK 1032668T3 DK 98961795 T DK98961795 T DK 98961795T DK 98961795 T DK98961795 T DK 98961795T DK 1032668 T3 DK1032668 T3 DK 1032668T3
Authority
DK
Denmark
Prior art keywords
polypeptides
present
methods
treatment
diagnosis
Prior art date
Application number
DK98961795T
Other languages
English (en)
Inventor
Audrey Goddard
Austin L Gurney
Kenneth J Hillan
David A Lawrence
Margaret Ann Roy
David Botstein
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK1032668T3 publication Critical patent/DK1032668T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factors [FGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
DK98961795T 1997-11-25 1998-11-25 Fibroblast vækstfaktor 19 DK1032668T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6684097P 1997-11-25 1997-11-25
US15834298A 1998-09-21 1998-09-21
PCT/US1998/025190 WO1999027100A1 (en) 1997-11-25 1998-11-25 Fibroblast growth factor-19

Publications (1)

Publication Number Publication Date
DK1032668T3 true DK1032668T3 (da) 2008-09-29

Family

ID=26747212

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98961795T DK1032668T3 (da) 1997-11-25 1998-11-25 Fibroblast vækstfaktor 19

Country Status (11)

Country Link
EP (1) EP1032668B1 (da)
JP (1) JP3653469B2 (da)
KR (2) KR20050009764A (da)
AT (1) ATE397063T1 (da)
AU (1) AU733222B2 (da)
CA (1) CA2309783C (da)
DE (1) DE69839571D1 (da)
DK (1) DK1032668T3 (da)
IL (2) IL136055A0 (da)
NZ (1) NZ504425A (da)
WO (1) WO1999027100A1 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6787640B2 (en) 1995-06-05 2004-09-07 Human Genome Sciences, Inc. Fibroblast growth factor 14
US6605441B1 (en) 1995-06-05 2003-08-12 Human Genome Sciences, Inc. Antibodies against fibroblast growth factor 11
US20050043234A1 (en) 1996-10-16 2005-02-24 Deisher Theresa A. Novel FGF homologs
AU733222B2 (en) * 1997-11-25 2001-05-10 Genentech Inc. Fibroblast growth factor-19
WO2000056890A1 (en) * 1999-03-19 2000-09-28 Chiron Corporation Human fgf gene and gene expression products
AU4851900A (en) * 1999-06-09 2000-12-28 Genentech Inc. Compositions and methods for the treatment of tumor
US7459540B1 (en) * 1999-09-07 2008-12-02 Amgen Inc. Fibroblast growth factor-like polypeptides
IL148188A0 (en) * 1999-09-08 2002-09-12 Genentech Inc Fibroblast growth factor-19 (fgf-19) nucleic acids and polypeptides and methods of use for the treatment of obesity
CA2384089A1 (en) * 1999-09-08 2001-03-15 Genentech, Inc. Fibroblast growth factor-19 (fgf-19) nucleic acids and polypeptides and methods of use for the treatment of obesity
US6716626B1 (en) 1999-11-18 2004-04-06 Chiron Corporation Human FGF-21 nucleic acids
PT1232264E (pt) * 1999-11-18 2009-11-26 Novartis Vaccines & Diagnostic Gene fgf-21 humano e produtos da expressão do gene
WO2001049849A1 (en) * 2000-01-05 2001-07-12 Zymogenetics, Inc. Novel fgf homolog zfgf11
CA2396401A1 (en) * 2000-01-05 2001-07-12 Zymogenetics, Inc. Novel fgf homolog zfgf12
CA2398603A1 (en) * 2000-02-15 2001-08-23 Amgen, Inc. Fibroblast growth factor-23 molecules and uses thereof
EP1947182A1 (en) * 2000-02-15 2008-07-23 Amgen Inc. Fibroblast growth factor-23 molecules and uses thereof
CN1311212A (zh) * 2000-03-02 2001-09-05 上海博德基因开发有限公司 一种新的多肽——人成纤维细胞生长因子14和编码这种多肽的多核苷酸
EP1286704B1 (en) * 2000-06-02 2014-07-23 Board of Regents, The University of Texas System ETHYLENEDICYSTEINE (EC)-glucose analog CONJUGATES
AU2002230531A1 (en) * 2000-11-22 2002-06-03 Bayer Corporation Use of fgf-19 for inhibiting angiogenesis
FI20011542A (fi) * 2001-07-13 2003-01-14 Fit Biotech Oyj Plc Urosognaasigeenin monistuman käyttö
EP1553912A4 (en) 2002-06-07 2007-08-08 Genentech Inc COMPOSITIONS AND METHODS FOR TUMOR DIAGNOSIS AND TREATMENT
US20040136970A1 (en) 2002-10-07 2004-07-15 Ellsworth Jeff L. Methods for administering FGF18
US7678373B2 (en) 2006-02-10 2010-03-16 Genentech, Inc. Anti-FGF19 antibodies and methods using same
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
AU2008299779B2 (en) 2007-08-03 2013-05-16 Genentech, Inc. Humanized anti-FGF19 antagonists and methods using same
WO2009105709A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
JOP20190083A1 (ar) 2008-06-04 2017-06-16 Amgen Inc بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
US9279013B2 (en) 2008-10-10 2016-03-08 Amgen Inc. FGF-21 mutants comprising polyethylene glycol and uses thereof
CN102245675B (zh) 2008-12-16 2013-08-14 道康宁公司 硅氧烷的制备
CN107188950B (zh) 2009-05-05 2021-09-28 安姆根有限公司 Fgf21突变体及其用途
US20120052069A1 (en) 2009-05-05 2012-03-01 Amgen Inc Fgf21 mutants and uses thereof
CA2764835A1 (en) 2009-06-17 2010-12-23 Amgen Inc. Chimeric fgf19 polypeptides and uses thereof
RU2573896C2 (ru) * 2009-10-15 2016-01-27 Дженентек, Инк. Химерные факторы роста фибробластов с измененной рецепторной специфичностью
UA109888C2 (uk) 2009-12-07 2015-10-26 ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
TWI728373B (zh) 2013-12-23 2021-05-21 美商建南德克公司 抗體及使用方法
EP3108893A1 (en) 2015-06-25 2016-12-28 Universite Claude Bernard - Lyon 1 Novel therapeutic use of fgf19
KR102315601B1 (ko) 2020-05-13 2021-10-21 전남대학교산학협력단 재조합 벡터 및 이를 이용한 재조합 섬유아세포 성장인자 19의 제조 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999014327A2 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Genes amplified in tumours, antibodies against the proteins coded thereby, and their use in diagnosis and treatment of cancer
WO1999014328A2 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU733222B2 (en) * 1997-11-25 2001-05-10 Genentech Inc. Fibroblast growth factor-19
AU5816799A (en) * 1998-09-10 2000-04-03 Genentech Inc. Compositions and methods for the treatment of tumor
EP1114152A2 (en) * 1998-09-16 2001-07-11 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same

Also Published As

Publication number Publication date
AU1703399A (en) 1999-06-15
KR20010032405A (ko) 2001-04-16
KR20050009764A (ko) 2005-01-25
WO1999027100A9 (en) 2000-05-11
EP1032668B1 (en) 2008-05-28
JP2002503446A (ja) 2002-02-05
DE69839571D1 (de) 2008-07-10
EP1032668A1 (en) 2000-09-06
AU733222B2 (en) 2001-05-10
NZ504425A (en) 2001-10-26
CA2309783C (en) 2011-06-28
IL193366A0 (en) 2009-02-11
ATE397063T1 (de) 2008-06-15
JP3653469B2 (ja) 2005-05-25
KR100506786B1 (ko) 2005-08-08
IL136055A0 (en) 2001-05-20
CA2309783A1 (en) 1999-06-03
WO1999027100A1 (en) 1999-06-03

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