ATE397063T1 - Fibroblasten-wachstumsfaktor-19 - Google Patents

Fibroblasten-wachstumsfaktor-19

Info

Publication number
ATE397063T1
ATE397063T1 AT98961795T AT98961795T ATE397063T1 AT E397063 T1 ATE397063 T1 AT E397063T1 AT 98961795 T AT98961795 T AT 98961795T AT 98961795 T AT98961795 T AT 98961795T AT E397063 T1 ATE397063 T1 AT E397063T1
Authority
AT
Austria
Prior art keywords
polypeptides
present
methods
treatment
diagnosis
Prior art date
Application number
AT98961795T
Other languages
English (en)
Inventor
David Botstein
Audrey Goddard
Austin Gurney
Kenneth Hillan
David Lawrence
Margaret Roy
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE397063T1 publication Critical patent/ATE397063T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98961795T 1997-11-25 1998-11-25 Fibroblasten-wachstumsfaktor-19 ATE397063T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6684097P 1997-11-25 1997-11-25
US15834298A 1998-09-21 1998-09-21

Publications (1)

Publication Number Publication Date
ATE397063T1 true ATE397063T1 (de) 2008-06-15

Family

ID=26747212

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98961795T ATE397063T1 (de) 1997-11-25 1998-11-25 Fibroblasten-wachstumsfaktor-19

Country Status (11)

Country Link
EP (1) EP1032668B1 (de)
JP (1) JP3653469B2 (de)
KR (2) KR100506786B1 (de)
AT (1) ATE397063T1 (de)
AU (1) AU733222B2 (de)
CA (1) CA2309783C (de)
DE (1) DE69839571D1 (de)
DK (1) DK1032668T3 (de)
IL (2) IL136055A0 (de)
NZ (1) NZ504425A (de)
WO (1) WO1999027100A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6787640B2 (en) 1995-06-05 2004-09-07 Human Genome Sciences, Inc. Fibroblast growth factor 14
US6605441B1 (en) 1995-06-05 2003-08-12 Human Genome Sciences, Inc. Antibodies against fibroblast growth factor 11
US20050043234A1 (en) 1996-10-16 2005-02-24 Deisher Theresa A. Novel FGF homologs
KR100506786B1 (ko) * 1997-11-25 2005-08-08 제넨테크, 인크. 섬유아세포 성장인자-19
AU3900000A (en) * 1999-03-19 2000-10-09 Chiron Corporation Human fgf gene and gene expression products
CA2371434A1 (en) * 1999-06-09 2000-12-14 Genentech, Inc. Compositions and methods for the treatment of tumor
US7459540B1 (en) * 1999-09-07 2008-12-02 Amgen Inc. Fibroblast growth factor-like polypeptides
ATE326532T1 (de) * 1999-09-08 2006-06-15 Genentech Inc Fibroblasten-wachstumsfaktor-19 (fgf-19) nukleinsäure und polypeptide und verfahren zu deren verwendung für behandlung von fettleibigkeit
JP2004500037A (ja) * 1999-09-08 2004-01-08 ジェネンテック・インコーポレーテッド 繊維芽細胞成長因子−１９（ｆｇｆ−１９）核酸及びポリペプチド並びに肥満の治療のための利用の方法
PT1232264E (pt) * 1999-11-18 2009-11-26 Novartis Vaccines & Diagnostic Gene fgf-21 humano e produtos da expressão do gene
US6716626B1 (en) 1999-11-18 2004-04-06 Chiron Corporation Human FGF-21 nucleic acids
AU2631001A (en) * 2000-01-05 2001-07-16 Zymogenetics Inc. Novel fgf homolog zfgf11
WO2001049740A1 (en) * 2000-01-05 2001-07-12 Zymogenetics, Inc. Novel fgf homolog zfgf12
EP1947182A1 (de) * 2000-02-15 2008-07-23 Amgen Inc. Fibroblastenwachstumsfaktor-23-Moleküle und ihre Verwendung
CA2398603A1 (en) * 2000-02-15 2001-08-23 Amgen, Inc. Fibroblast growth factor-23 molecules and uses thereof
CN1311212A (zh) * 2000-03-02 2001-09-05 上海博德基因开发有限公司 一种新的多肽——人成纤维细胞生长因子14和编码这种多肽的多核苷酸
CN1292798C (zh) * 2000-06-02 2007-01-03 德克萨斯州立大学董事会 乙二半胱氨酸(ec)－药物缀合物
US20030045489A1 (en) * 2000-11-22 2003-03-06 Murphy John E. Methods for modulating angiogenesis
FI20011542A (fi) * 2001-07-13 2003-01-14 Fit Biotech Oyj Plc Urosognaasigeenin monistuman käyttö
JP2005528905A (ja) 2002-06-07 2005-09-29 ジェネンテック・インコーポレーテッド 腫瘍の診断と治療のための組成物と方法
AU2003279835B2 (en) 2002-10-07 2009-09-10 Zymogenetics, Inc. Methods of administering FGF18
US7678373B2 (en) 2006-02-10 2010-03-16 Genentech, Inc. Anti-FGF19 antibodies and methods using same
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
US8236307B2 (en) 2007-08-03 2012-08-07 Genentech, Inc. Humanized anti-FGF19 antagonists and methods using same
EP2252196A4 (de) 2008-02-21 2013-05-15 Dexcom Inc Systeme und verfahren zur verarbeitung, übertragung und anzeige von sensordaten
JOP20190083A1 (ar) 2008-06-04 2017-06-16 Amgen Inc بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
SG195542A1 (en) 2008-10-10 2013-12-30 Amgen Inc Fgf21 mutants and uses thereof
WO2010074831A1 (en) 2008-12-16 2010-07-01 Dow Corning Corporation Preparation of siloxanes
TWI560197B (en) 2009-05-05 2016-12-01 Amgen Inc Fgf21 mutants and uses thereof
CA2760674A1 (en) 2009-05-05 2010-11-11 Amgen Inc. Fgf21 mutants and uses thereof
WO2010148142A1 (en) * 2009-06-17 2010-12-23 Amgen Inc. Chimeric fgf19 polypeptides and uses thereof
EP2488643A4 (de) * 2009-10-15 2013-07-03 Hoffmann La Roche Chimäre fibroblastwachstumsfaktoren mit veränderter rezeptorspezifizität
UA109888C2 (uk) 2009-12-07 2015-10-26 ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
TWI728373B (zh) 2013-12-23 2021-05-21 美商建南德克公司 抗體及使用方法
EP3108893A1 (de) 2015-06-25 2016-12-28 Universite Claude Bernard - Lyon 1 Neuartige therapeutische verwendung von fgf19
KR102315601B1 (ko) 2020-05-13 2021-10-21 전남대학교산학협력단 재조합 벡터 및 이를 이용한 재조합 섬유아세포 성장인자 19의 제조 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999014328A2 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU9312198A (en) * 1997-09-17 1999-04-05 Genentech Inc. Genes amplified in tumours, antibodies against the proteins encoded thereby, andtheir use in diagnosis and treatment of cancer
KR100506786B1 (ko) * 1997-11-25 2005-08-08 제넨테크, 인크. 섬유아세포 성장인자-19
AU5816799A (en) * 1998-09-10 2000-04-03 Genentech Inc. Compositions and methods for the treatment of tumor
CA2343577A1 (en) * 1998-09-16 2000-03-23 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same

Also Published As

Publication number Publication date
IL193366A0 (en) 2009-02-11
KR20010032405A (ko) 2001-04-16
DE69839571D1 (de) 2008-07-10
DK1032668T3 (da) 2008-09-29
CA2309783A1 (en) 1999-06-03
CA2309783C (en) 2011-06-28
JP2002503446A (ja) 2002-02-05
IL136055A0 (en) 2001-05-20
NZ504425A (en) 2001-10-26
WO1999027100A9 (en) 2000-05-11
EP1032668B1 (de) 2008-05-28
EP1032668A1 (de) 2000-09-06
AU733222B2 (en) 2001-05-10
KR100506786B1 (ko) 2005-08-08
JP3653469B2 (ja) 2005-05-25
KR20050009764A (ko) 2005-01-25
WO1999027100A1 (en) 1999-06-03
AU1703399A (en) 1999-06-15

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Legal Events

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