WO2000053755A3 - Compositions and methods for the treatment of tumor - Google Patents
Compositions and methods for the treatment of tumor Download PDFInfo
- Publication number
- WO2000053755A3 WO2000053755A3 PCT/US2000/000376 US0000376W WO0053755A3 WO 2000053755 A3 WO2000053755 A3 WO 2000053755A3 US 0000376 W US0000376 W US 0000376W WO 0053755 A3 WO0053755 A3 WO 0053755A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptides
- present
- treatment
- methods
- tumor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Priority Applications (432)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU24952/00A AU2495200A (en) | 1999-03-08 | 2000-01-06 | Compositions and methods for the treatment of tumor |
AU28837/00A AU2883700A (en) | 1999-06-23 | 2000-02-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
JP2000603377A JP2004513602A (en) | 1999-03-08 | 2000-02-18 | Secreted and transmembrane polypeptides and nucleic acids encoding them |
KR1020017011399A KR20030002292A (en) | 1999-03-08 | 2000-02-18 | Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same |
PCT/US2000/004341 WO2000053756A2 (en) | 1999-03-08 | 2000-02-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002361840A CA2361840A1 (en) | 1999-03-08 | 2000-02-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
PCT/US2000/004342 WO2000078961A1 (en) | 1999-06-23 | 2000-02-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP00907314A EP1263948A2 (en) | 1999-03-08 | 2000-02-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
JP2000603379A JP2004516227A (en) | 1999-03-08 | 2000-03-02 | Compositions and methods for treating immune-related diseases |
EP00913764A EP1220905A2 (en) | 1999-03-08 | 2000-03-02 | Composition and methods for the treatment of immune related diseases |
AU35144/00A AU3514400A (en) | 1999-03-08 | 2000-03-02 | Compositions and methods for the treatment of immune related diseases |
PCT/US2000/005841 WO2000053758A2 (en) | 1999-03-08 | 2000-03-02 | Compositions and methods for the treatment of immune related diseases |
CA002362427A CA2362427A1 (en) | 1999-03-08 | 2000-03-02 | Compositions and methods for the treatment of immune related diseases |
KR1020017011406A KR20010103046A (en) | 1999-03-08 | 2000-03-02 | Compositions and Methods for the Treatment of Immune Related Diseases |
JP2001500766A JP2004522402A (en) | 1999-06-02 | 2000-03-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002383254A CA2383254A1 (en) | 1999-06-02 | 2000-03-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP00916675A EP1210418B1 (en) | 1999-06-02 | 2000-03-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
AU37743/00A AU3774300A (en) | 1999-06-02 | 2000-03-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
PCT/US2000/008439 WO2000073454A1 (en) | 1999-06-02 | 2000-03-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
AT00916675T ATE478145T1 (en) | 1999-06-02 | 2000-03-30 | SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS CODING THEREFOR |
ES00939307T ES2307515T3 (en) | 1999-06-02 | 2000-05-17 | ACTIVATION OR INHIBITION OF ANGIOGENESIS AND CARDIOVASCULARIZATION. |
PT00939307T PT1212417E (en) | 1999-06-02 | 2000-05-17 | Promotion or inhibition of angiogenesis and cardiovascularization |
JP2001500757A JP4297317B2 (en) | 1999-06-02 | 2000-05-17 | Promotion or inhibition of angiogenesis and cardiovascularization |
DK00939307T DK1212417T3 (en) | 1999-06-02 | 2000-05-17 | Promotion or inhibition of angiogenesis and vascularization |
CA002376116A CA2376116A1 (en) | 1999-06-02 | 2000-05-17 | Promotion or inhibition of angiogenesis and cardiovascularization |
EP00939307A EP1212417B1 (en) | 1999-06-02 | 2000-05-17 | Promotion or inhibition of angiogenesis and cardiovascularization |
AT00939307T ATE393825T1 (en) | 1999-06-02 | 2000-05-17 | STIMULATION OR INHIBITION OF ANGIOGENESIS AND CARDIAC VASCULARIZATION |
PCT/US2000/013705 WO2000073445A2 (en) | 1999-06-02 | 2000-05-17 | Interleukin-1-receptor associated kinase-3 (irak3) |
EP07005023A EP1867719A3 (en) | 1999-06-02 | 2000-05-30 | Methods and compositions for inhibiting neoplastic cell growth |
CA002373915A CA2373915A1 (en) | 1999-06-02 | 2000-05-30 | Methods and compositions for inhibiting neoplastic cell growth |
EP07005021A EP1873244A3 (en) | 1999-06-02 | 2000-05-30 | Methods and compositions for inhibiting neoplastic cell growth |
EP00941164A EP1185648B1 (en) | 1999-06-02 | 2000-05-30 | Methods and compositions for inhibiting neoplastic cell growth |
JP2001500672A JP2003524406A (en) | 1999-06-02 | 2000-05-30 | Compositions and methods for inhibiting tumor cell growth |
AT00941164T ATE357518T1 (en) | 1999-06-02 | 2000-05-30 | METHODS AND COMPOSITIONS FOR INHIBITING NEOPLASTIC CELL GROWTH |
EP07004855A EP1820860A3 (en) | 1999-06-02 | 2000-05-30 | Methods and compositions for inhibiting neoplastic cell growth |
DK00941164T DK1185648T3 (en) | 1999-06-02 | 2000-05-30 | Methods and compositions for inhibiting neoplastic cell growth |
PCT/US2000/014941 WO2000073348A2 (en) | 1999-06-02 | 2000-05-30 | Methods and compositions for inhibiting neoplastic cell growth |
ES00941164T ES2287020T3 (en) | 1999-06-02 | 2000-05-30 | PROCEDURE AND COMPOSITIONS TO INHIBIT THE GROWTH OF NEOPLASSIC CELLS. |
EP07005022A EP1870464A3 (en) | 1999-06-02 | 2000-05-30 | Methods and compositions for inhibiting neoplastic cell growth |
PCT/US2000/015264 WO2000073452A2 (en) | 1999-06-02 | 2000-06-02 | Compositions and methods for the treatment of immune related diseases |
AU63910/00A AU6391000A (en) | 1999-07-28 | 2000-07-28 | Method of preventing the injury or death of retinal cells and treating ocular diseases |
PCT/US2000/020710 WO2001009327A2 (en) | 1999-07-28 | 2000-07-28 | Method of preventing the injury or death of retinal cells and treating ocular diseases |
JP2001550255A JP4280444B2 (en) | 2000-01-06 | 2000-11-08 | Compositions and methods for inhibiting neoplastic cell growth |
PCT/US2000/030952 WO2001049715A2 (en) | 2000-01-06 | 2000-11-08 | Methods and compositions for inhibiting neoplastic cell growth |
EP00982096A EP1244784A2 (en) | 2000-01-06 | 2000-11-08 | Methods and compositions for inhibiting neoplastic cell growth |
CA002390685A CA2390685C (en) | 2000-01-06 | 2000-11-08 | Methods and compositions for inhibiting neoplastic cell growth |
AU19167/01A AU1916701A (en) | 2000-01-06 | 2000-11-08 | Methods and compositions for inhibiting neoplastic cell growth |
EP06000588A EP1690873A3 (en) | 1999-12-01 | 2000-12-01 | Composition and methods for the diagnosis of tumours |
EP06000583A EP1686134A3 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002492049A CA2492049A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002491258A CA2491258A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002391455A CA2391455A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
PCT/US2000/032678 WO2001040466A2 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
AU20554/01A AU2055401A (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002491610A CA2491610A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000589A EP1661997A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002491433A CA2491433A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000587A EP1690872A3 (en) | 1999-12-01 | 2000-12-01 | Composition and methods for the diagnosis of tumours |
EP00983846A EP1250426A2 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding same |
EP06000582A EP1666495A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000581A EP1666494A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002496312A CA2496312A1 (en) | 1999-12-01 | 2000-12-01 | Colon tumour marker pro4799 polypeptides and nucleic acids encoding the same |
JP2001542531A JP2004522404A (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding them |
EP05025102A EP1672070A3 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002490853A CA2490853A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP10005292A EP2228446A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptieds and nucleic acids encoding the same |
CA002490909A CA2490909A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002492070A CA2492070A1 (en) | 1999-12-01 | 2000-12-01 | Lung tumor marker pro4329 polypeptides and nucleic acids encoding the same |
CA002494705A CA2494705A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000585A EP1661996A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000584A EP1669371A3 (en) | 1999-12-01 | 2000-12-01 | Composition and methods for the diagnosis of tumours |
CA2709291A CA2709291A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000586A EP1688497A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/918,585 US20030060406A1 (en) | 1997-10-17 | 2001-07-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/929,769 US6914130B2 (en) | 1998-06-17 | 2001-08-14 | Compositions and methods for the diagnosis and treatment of tumor |
US09/941,992 US20030082546A1 (en) | 1996-11-06 | 2001-08-28 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/946,374 US20030073129A1 (en) | 1998-09-01 | 2001-09-04 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,193 US20030073624A1 (en) | 1997-10-17 | 2001-10-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,295 US20020156006A1 (en) | 1997-10-17 | 2001-10-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,299 US20030199435A1 (en) | 1997-10-17 | 2001-10-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,192 US20020177553A1 (en) | 1997-10-17 | 2001-10-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,298 US20030134785A1 (en) | 1997-10-17 | 2001-10-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,194 US20030195333A1 (en) | 1997-10-17 | 2001-10-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,189 US6972325B2 (en) | 1997-10-17 | 2001-10-15 | PRO273 polypeptides |
US09/978,188 US20030139328A1 (en) | 1997-10-17 | 2001-10-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,191 US20030050239A1 (en) | 1997-10-17 | 2001-10-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,802 US20030199674A1 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,403 US20030050240A1 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,824 US20050124789A9 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,681 US20030195148A1 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,375 US7196165B2 (en) | 1997-10-17 | 2001-10-16 | PRO363 polypeptides |
US09/978,423 US20030069178A1 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,585 US20030049633A1 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,564 US7195760B2 (en) | 1997-10-17 | 2001-10-16 | Anti-pro363 antibodies |
US09/978,544 US20030199436A1 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,757 US20030083248A1 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,643 US20030104998A1 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/981,915 US20030054986A1 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,697 US20020169284A1 (en) | 1997-10-17 | 2001-10-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/981,915 US7285623B2 (en) | 1997-10-17 | 2001-10-16 | PRO337 polypeptides |
US09/978,665 US7294700B2 (en) | 1997-10-17 | 2001-10-16 | Anti-PRO846 antibodies |
US09/978,824 US20030055216A1 (en) | 1997-10-17 | 2001-10-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/210,028 US20030203446A1 (en) | 1998-10-07 | 2001-10-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/152,388 US20040223964A1 (en) | 1998-03-17 | 2001-10-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/160,502 US7220835B2 (en) | 1998-07-30 | 2001-10-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/165,247 US7112657B2 (en) | 1998-10-07 | 2001-10-19 | PRO697 polypeptides |
US10/145,124 US20030190701A1 (en) | 1998-04-30 | 2001-10-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/166,709 US20030104536A1 (en) | 1998-10-07 | 2001-10-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/164,829 US20030194780A1 (en) | 1998-04-29 | 2001-10-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/145,089 US7208575B2 (en) | 1998-10-07 | 2001-10-19 | PRO531 polypeptides |
US10/164,728 US20030186368A1 (en) | 1998-05-13 | 2001-10-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/165,067 US7279553B2 (en) | 1998-05-13 | 2001-10-19 | PRO1083 polypeptides |
US10/164,929 US20030194781A1 (en) | 1998-03-30 | 2001-10-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/143,029 US7105640B2 (en) | 1997-10-17 | 2001-10-19 | Anti-pro792 antibodies |
US10/165,036 US20050227342A1 (en) | 1998-10-07 | 2001-10-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/164,749 US20040029218A1 (en) | 1998-10-07 | 2001-10-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/162,521 US7067628B2 (en) | 1998-03-17 | 2001-10-19 | PRO788 polypeptides |
US10/145,017 US20030186365A1 (en) | 1998-03-26 | 2001-10-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,922 US20030195345A1 (en) | 1997-10-17 | 2001-10-21 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/020,445 US20030198994A1 (en) | 1997-10-17 | 2001-10-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/999,829 US20030195344A1 (en) | 1997-10-17 | 2001-10-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/999,830 US20030077700A1 (en) | 1997-10-17 | 2001-10-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/999,834 US20030064407A1 (en) | 1997-10-17 | 2001-10-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/017,081 US20030049684A1 (en) | 1997-10-17 | 2001-10-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/017,083 US20030148376A1 (en) | 1997-10-17 | 2001-10-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/017,086 US7122375B2 (en) | 1997-10-17 | 2001-10-24 | PRO274 nucleic acids |
US09/999,832 US20020192706A1 (en) | 1997-10-17 | 2001-10-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/999,832 US7132283B2 (en) | 1997-10-17 | 2001-10-24 | PRO273 polypeptides |
US10/017,085 US6974696B2 (en) | 1997-10-17 | 2001-10-24 | PRO853 nucleic acids |
US09/999,833 US6916648B2 (en) | 1997-10-17 | 2001-10-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/002,967 US20030148373A1 (en) | 1997-10-17 | 2001-10-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/017,084 US20030203402A1 (en) | 1997-10-17 | 2001-10-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,918 US20030211091A1 (en) | 1997-10-17 | 2001-10-25 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,925 US7037710B2 (en) | 1997-10-17 | 2001-10-25 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,921 US20030068648A1 (en) | 1997-10-17 | 2001-10-25 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,928 US20030215905A1 (en) | 1998-10-07 | 2001-10-25 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/016,177 US20030073131A1 (en) | 1997-10-17 | 2001-10-25 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,929 US7019124B2 (en) | 1997-10-17 | 2001-10-25 | PRO788 nucleic acids |
US10/013,927 US7189529B2 (en) | 1997-10-17 | 2001-10-25 | PRO792 nucleic acids |
US10/013,920 US20040006219A1 (en) | 1997-10-17 | 2001-10-25 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,917 US7029874B2 (en) | 1998-03-17 | 2001-10-25 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,923 US7169912B2 (en) | 1997-10-17 | 2001-10-25 | PRO1017 nucleic acids |
US10/013,926 US7074593B2 (en) | 1998-04-01 | 2001-10-25 | PRO 703 nucleic acids |
US09/990,427 US20030073809A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,443 US20030054987A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,456 US20020137890A1 (en) | 1997-03-31 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/991,854 US20030059780A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/993,583 US7074897B2 (en) | 1997-06-16 | 2001-11-14 | Pro943 polypeptides |
US09/990,440 US20030060407A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,438 US20030027754A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,562 US20030027985A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/993,687 US20020198149A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,444 US6930170B2 (en) | 1997-06-16 | 2001-11-14 | PRO1184 polypeptides |
US09/990,442 US20020132252A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/993,469 US20030068623A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,711 US20030032023A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/991,163 US20020132253A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,726 US20030054359A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/993,748 US20030069403A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/992,521 US20030083461A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/992,598 US6956108B2 (en) | 1997-06-16 | 2001-11-14 | PRO1184 antibodies |
US09/993,667 US20030022187A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,436 US20020198148A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/991,073 US20020127576A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,585 US7166282B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,529 US20030134284A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,641 US20030224358A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,653 US7034122B2 (en) | 1997-06-16 | 2001-11-15 | Antibodies to PRO1159 polypeptides |
US09/997,514 US7019116B2 (en) | 1997-06-16 | 2001-11-15 | PRO 1387 polypeptides |
US09/997,440 US20030059833A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,559 US20030054403A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,585 US20030119055A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,428 US20030027162A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,641 US7112656B2 (en) | 1997-06-16 | 2001-11-15 | PRO1312 polypeptides |
US09/997,601 US20030054404A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,384 US7119177B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,628 US20030059782A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,529 US7309761B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/998,041 US7309775B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,542 US20030068647A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/998,156 US20030044806A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,666 US7244816B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,857 US20030064375A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,614 US20030124531A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,333 US6953836B2 (en) | 1997-06-16 | 2001-11-15 | PRO844 polypeptides |
US09/997,666 US20030027163A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,573 US20030049682A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,349 US7034106B2 (en) | 1997-06-16 | 2001-11-15 | Pro1159 polypeptides |
US09/997,683 US20030059783A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,384 US20030087305A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/998,041 US20030119001A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,601 US7189814B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/991,157 US7101687B2 (en) | 1997-06-16 | 2001-11-16 | Nucleic acids encoding PRO943 |
US09/990,437 US20030045463A1 (en) | 1997-06-16 | 2001-11-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/991,181 US6913919B2 (en) | 1997-06-16 | 2001-11-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/991,172 US20030050457A1 (en) | 1997-06-16 | 2001-11-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,441 US7041804B2 (en) | 1997-06-16 | 2001-11-16 | Antibodies to PRO1387 polypeptides |
US09/991,150 US20030194760A1 (en) | 1997-06-16 | 2001-11-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,279 US7083978B2 (en) | 1997-06-16 | 2001-11-19 | Nucleic acid encoding PRO1111 polypeptides |
US09/989,734 US7491529B2 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,722 US20020072067A1 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,721 US20020142961A1 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,726 US7018811B2 (en) | 1997-06-16 | 2001-11-19 | Nucleic acids encoding PRO189 polypeptides |
US09/989,729 US20030059831A1 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,862 US20030130182A1 (en) | 1997-11-05 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,727 US20020072497A1 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,723 US20020072092A1 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,735 US6972185B2 (en) | 1997-06-16 | 2001-11-19 | Nucleic acids encoding PRO844 polypeptides |
US09/989,328 US7056736B2 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,732 US7037679B2 (en) | 1997-06-16 | 2001-11-19 | Nucleic acids encoding PRO1184 polypeptides |
US09/989,724 US7060812B2 (en) | 1997-06-16 | 2001-11-20 | PRO1312 nucleic acids |
US09/989,728 US7029873B2 (en) | 1997-06-16 | 2001-11-20 | Nucleic acids to PRO1387 polypeptides |
US09/989,731 US20020103125A1 (en) | 1997-06-16 | 2001-11-20 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,725 US20030139329A1 (en) | 1997-06-16 | 2001-11-20 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,293 US7034136B2 (en) | 1997-06-16 | 2001-11-20 | Nucleic acids encoding PRO1159 polypeptides |
US09/989,730 US7157247B2 (en) | 1997-06-16 | 2001-11-20 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/001,054 US20020192209A1 (en) | 1997-09-17 | 2001-11-30 | Methods and compositions for inhibiting neoplastic cell growth |
US10/007,236 US7034123B2 (en) | 1998-09-01 | 2001-12-06 | Anti-PRO1347 antibodies |
US10/006,856 US7538086B2 (en) | 1998-09-01 | 2001-12-06 | PRO1303 polypeptides |
US10/007,194 US7041805B2 (en) | 1998-09-01 | 2001-12-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/006,172 US7081514B2 (en) | 1998-09-01 | 2001-12-06 | PRO1347 polypeptides |
US10/006,130 US7098312B2 (en) | 1998-09-01 | 2001-12-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/006,485 US7026448B2 (en) | 1998-09-01 | 2001-12-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/006,818 US20030054406A1 (en) | 1998-09-01 | 2001-12-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/006,063 US20030114652A1 (en) | 1998-09-01 | 2001-12-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/006,117 US7071304B2 (en) | 1998-09-01 | 2001-12-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/006,041 US6951921B2 (en) | 1998-09-01 | 2001-12-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/006,768 US6936697B2 (en) | 1998-09-01 | 2001-12-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/006,746 US7026449B2 (en) | 1999-01-05 | 2001-12-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/006,116 US20030082626A1 (en) | 1998-09-01 | 2001-12-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/012,755 US20030096955A1 (en) | 1998-09-01 | 2001-12-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/012,121 US7022817B2 (en) | 1998-09-01 | 2001-12-07 | PRO1325 polypeptides |
US10/011,795 US7012131B2 (en) | 1998-09-01 | 2001-12-07 | Pro1410 polypeptides |
US10/012,754 US7375184B2 (en) | 1998-09-01 | 2001-12-07 | PRO1382 polypeptides |
US10/011,692 US20030109672A1 (en) | 1998-09-01 | 2001-12-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/012,752 US7026455B2 (en) | 1998-09-01 | 2001-12-07 | Anti-pro 1343 antibodies |
US10/012,231 US6924355B2 (en) | 1998-09-01 | 2001-12-07 | PRO1343 polypeptides |
US10/012,101 US20030187239A1 (en) | 1998-09-01 | 2001-12-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/012,753 US7488796B2 (en) | 1998-09-01 | 2001-12-07 | PRO1269 polypeptides |
US10/012,064 US6953841B2 (en) | 1999-01-05 | 2001-12-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/012,149 US7038019B2 (en) | 1998-09-01 | 2001-12-07 | Antibodies to PRO1410 |
US10/011,671 US20030096954A1 (en) | 1998-09-01 | 2001-12-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/012,137 US20030187189A1 (en) | 1998-09-01 | 2001-12-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/011,833 US6951920B2 (en) | 1998-09-01 | 2001-12-07 | PRO1340 polypeptides |
US10/012,237 US20030191281A1 (en) | 1998-09-01 | 2001-12-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/012,754 US20030187191A1 (en) | 1998-09-01 | 2001-12-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,909 US20030186318A1 (en) | 1999-01-05 | 2001-12-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,915 US20030204053A1 (en) | 1998-09-01 | 2001-12-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,910 US7057018B2 (en) | 1999-01-05 | 2001-12-10 | Pro 1474 polypeptides |
US10/015,822 US20030130491A1 (en) | 1998-09-01 | 2001-12-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,911 US20030187193A1 (en) | 1998-09-01 | 2001-12-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,913 US20030083462A1 (en) | 1999-01-05 | 2001-12-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,907 US20030064925A1 (en) | 1998-09-01 | 2001-12-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,430 US20030092883A1 (en) | 1998-09-01 | 2001-12-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/013,906 US20030191282A1 (en) | 1998-09-01 | 2001-12-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,519 US7033785B2 (en) | 1998-09-01 | 2001-12-11 | PRO1347 nucleic acids |
US10/015,480 US7074912B2 (en) | 1998-09-01 | 2001-12-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,869 US7189530B2 (en) | 1998-09-01 | 2001-12-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,671 US6946263B2 (en) | 1998-09-01 | 2001-12-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,869 US20030073130A1 (en) | 1998-09-01 | 2001-12-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,653 US20030187195A1 (en) | 1998-09-01 | 2001-12-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,389 US6936436B2 (en) | 1998-09-01 | 2001-12-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,499 US20030065142A1 (en) | 1998-09-01 | 2001-12-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,393 US6951737B2 (en) | 1998-09-01 | 2001-12-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,386 US7022498B2 (en) | 1998-09-01 | 2001-12-12 | Pro 1325 nucleic acids |
US10/015,391 US20030120053A1 (en) | 1998-09-01 | 2001-12-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,387 US20030135034A1 (en) | 1998-09-01 | 2001-12-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,390 US20030216562A1 (en) | 1998-09-01 | 2001-12-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,385 US20030195347A1 (en) | 1998-09-01 | 2001-12-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,388 US20030191299A1 (en) | 1998-09-01 | 2001-12-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/015,715 US7033786B2 (en) | 1998-09-01 | 2001-12-12 | Pro1340 nucleic acids |
US10/017,407 US20030125535A1 (en) | 1998-09-01 | 2001-12-13 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/017,610 US20030113795A1 (en) | 1998-09-01 | 2001-12-13 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/017,867 US20030180792A1 (en) | 1998-09-01 | 2001-12-13 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/020,063 US20030119097A1 (en) | 1999-01-05 | 2001-12-13 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/017,306 US20030170718A1 (en) | 1998-09-01 | 2001-12-13 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/017,527 US20030082628A1 (en) | 1998-09-01 | 2001-12-13 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/028,072 US20030004311A1 (en) | 1997-06-18 | 2001-12-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/978,187 US20030096744A1 (en) | 1997-10-17 | 2002-01-28 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/081,056 US20040043927A1 (en) | 1997-09-19 | 2002-02-20 | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
US10/119,480 US20040087769A1 (en) | 1998-09-10 | 2002-04-09 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,040 US20030082759A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,042 US20030096386A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,041 US20030077776A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,047 US20030077778A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,059 US20030190721A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,046 US20030194791A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,051 US20030092147A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,044 US20030190717A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,045 US20030073210A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,055 US20030190718A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,058 US20030190720A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,061 US20030082761A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,048 US20030199051A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,043 US7220831B2 (en) | 1997-03-31 | 2002-04-12 | PRO235 polypeptides |
US10/121,054 US20030199054A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,050 US20030054516A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,056 US20030082760A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,060 US20030190722A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,063 US20030199055A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,062 US20030077779A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,052 US20030199052A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,049 US20030022239A1 (en) | 1997-06-18 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,053 US20030199053A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,057 US20030190719A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,322 US20030199059A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,213 US20030199057A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,771 US20030199060A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,212 US7276577B2 (en) | 1997-03-31 | 2002-04-15 | PRO1866 polypeptides |
US10/123,215 US7291329B2 (en) | 1997-03-31 | 2002-04-15 | Antibodies against PRO4406 |
US10/123,154 US20030190724A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,214 US7343721B2 (en) | 1997-03-31 | 2002-04-15 | PRO4406 polypeptide |
US10/123,213 US7193048B2 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,261 US20030068796A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,109 US20030190723A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,262 US20030049816A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,292 US20030073211A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,235 US20030082762A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,236 US20030068795A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,156 US20030194792A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,157 US20030190725A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,291 US20030199058A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,155 US20030068794A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,108 US7635478B2 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,902 US20030077781A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,913 US20030203462A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,907 US7084258B2 (en) | 1997-03-31 | 2002-04-16 | Antibodies against the PRO862 polypeptides |
US10/123,911 US7408032B2 (en) | 1997-03-31 | 2002-04-16 | PRO1188 polypeptides |
US10/123,905 US20030087344A1 (en) | 1997-06-18 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,908 US7335728B2 (en) | 1997-03-31 | 2002-04-16 | PRO1310 polypeptides |
US10/123,910 US7329404B2 (en) | 1997-03-31 | 2002-04-16 | Antibodies against PRO1310 |
US10/123,905 US7285625B2 (en) | 1997-06-18 | 2002-04-16 | PRO536 polypeptides |
US10/123,909 US7193049B2 (en) | 1997-03-31 | 2002-04-16 | PRO862 polypeptides |
US10/123,906 US20030190726A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,903 US20030073212A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,904 US20030022328A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,912 US20030100087A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,818 US20030082763A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,822 US7109305B2 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,821 US20030199023A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,814 US7105335B2 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,813 US7312307B2 (en) | 1997-03-31 | 2002-04-17 | PRO1056 polypeptides |
US10/124,816 US20030190728A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,823 US20030199062A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/125,704 US7357926B2 (en) | 1997-03-31 | 2002-04-17 | Antibodies against PRO1879 and the use thereof |
US10/124,817 US20030077786A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,820 US20030190729A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,819 US7285626B2 (en) | 1997-03-31 | 2002-04-17 | PRO1076 polypeptides |
US10/125,795 US7304131B2 (en) | 1997-03-31 | 2002-04-17 | PRO1483 polypeptides |
US10/125,805 US20030194794A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,824 US20030077659A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/125,924 US7342097B2 (en) | 1997-03-31 | 2002-04-19 | PRO1309 polypeptides |
US10/125,927 US20030190731A1 (en) | 1997-03-31 | 2002-04-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/125,931 US20030199063A1 (en) | 1997-03-31 | 2002-04-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/125,932 US7317079B2 (en) | 1997-03-31 | 2002-04-19 | PRO812 polypeptides |
US10/125,922 US7309762B2 (en) | 1997-03-31 | 2002-04-19 | PRO1360 polypeptides |
US10/127,831 US20030082689A1 (en) | 1997-03-31 | 2002-04-22 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/128,689 US20030087365A1 (en) | 1997-03-31 | 2002-04-23 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/131,825 US7282566B2 (en) | 1997-03-31 | 2002-04-24 | PRO1779 polypeptide |
US10/131,823 US7304132B2 (en) | 1997-03-31 | 2002-04-24 | PRO1693 polypeptides |
US10/131,817 US7291701B2 (en) | 1997-03-31 | 2002-04-24 | PRO1777 polypeptides |
US10/137,865 US20030032155A1 (en) | 1997-03-31 | 2002-05-03 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/137,868 US20030082764A1 (en) | 1997-03-31 | 2002-05-03 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/137,867 US20030207349A1 (en) | 1997-03-31 | 2002-05-03 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,020 US20030207415A1 (en) | 1997-03-31 | 2002-05-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,023 US20030207416A1 (en) | 1997-03-31 | 2002-05-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/139,980 US7247710B2 (en) | 1997-03-31 | 2002-05-06 | PRO4395 antibodies |
US10/140,470 US20030022331A1 (en) | 1997-03-31 | 2002-05-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,024 US20040058424A1 (en) | 1997-03-31 | 2002-05-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/139,963 US7288625B2 (en) | 1997-03-31 | 2002-05-06 | PRO4395 polypeptides |
US10/140,474 US20030032156A1 (en) | 1997-03-31 | 2002-05-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,865 US20030207420A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,809 US20030207418A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,928 US20030068798A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,864 US20030207419A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,808 US7425621B2 (en) | 1997-03-31 | 2002-05-07 | Antibodies against the PRO4401 polypeptide |
US10/140,805 US20030207417A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,860 US7307151B2 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,921 US7317080B2 (en) | 1997-03-31 | 2002-05-07 | PRO4303 polypeptides |
US10/140,925 US20030073215A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/141,754 US7361732B2 (en) | 1997-03-31 | 2002-05-08 | PRO4400 polypeptides |
US10/141,760 US7342104B2 (en) | 1997-03-31 | 2002-05-08 | Antibodies against the PRO4320 polypeptide |
US10/141,756 US7488586B2 (en) | 1997-03-31 | 2002-05-08 | PRO4409 polypeptides |
US10/141,701 US20030207421A1 (en) | 1997-03-31 | 2002-05-08 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/141,755 US7297764B2 (en) | 1997-03-31 | 2002-05-08 | PRO4318 polypeptides |
US10/143,114 US20030036180A1 (en) | 1997-03-31 | 2002-05-09 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/142,430 US7309766B2 (en) | 1997-03-31 | 2002-05-09 | PRO5774 polypeptides |
US10/142,425 US20030207424A1 (en) | 1997-03-31 | 2002-05-09 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/142,417 US7304133B2 (en) | 1997-03-31 | 2002-05-09 | PRO4389 polypeptides |
US10/143,113 US7329730B2 (en) | 1997-03-31 | 2002-05-09 | PRO4348 polypeptides |
US10/142,419 US7153941B2 (en) | 1997-03-31 | 2002-05-10 | Antibodies that bind PRO4994 polypeptides |
US10/142,431 US7285629B2 (en) | 1997-03-31 | 2002-05-10 | Pro5005 polypeptides |
US10/143,032 US7408033B2 (en) | 1997-03-31 | 2002-05-10 | PRO5995 polypeptides |
US10/142,423 US20030049817A1 (en) | 1997-03-31 | 2002-05-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/146,730 US20030207427A1 (en) | 1997-03-31 | 2002-05-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/146,792 US20030207428A1 (en) | 1997-03-31 | 2002-05-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/147,528 US20030219885A1 (en) | 1997-03-31 | 2002-05-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/147,519 US20030077791A1 (en) | 1997-03-31 | 2002-05-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/147,492 US20030082765A1 (en) | 1997-03-31 | 2002-05-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/147,536 US20040077064A1 (en) | 1997-03-31 | 2002-05-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/152,395 US7189534B2 (en) | 1997-03-31 | 2002-05-21 | PRO4320 polynucleotide |
US10/153,934 US20030129695A1 (en) | 1997-03-31 | 2002-05-22 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/156,843 US20030207805A1 (en) | 1997-06-18 | 2002-05-28 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/157,786 US20030208055A1 (en) | 1997-03-31 | 2002-05-29 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/157,782 US20030077792A1 (en) | 1997-03-31 | 2002-05-29 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/158,782 US20030082766A1 (en) | 1997-03-31 | 2002-05-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/158,791 US20030207429A1 (en) | 1997-03-31 | 2002-05-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/160,498 US20030073216A1 (en) | 1997-03-31 | 2002-05-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/176,913 US20030022298A1 (en) | 1997-09-15 | 2002-06-20 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/187,885 US20030032138A1 (en) | 1998-06-24 | 2002-07-02 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/197,942 US20030175882A1 (en) | 1998-09-10 | 2002-07-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
JP2002341509A JP4017507B2 (en) | 1999-06-02 | 2002-09-25 | Medicament containing polypeptide |
US11/021,329 US20050159591A1 (en) | 1999-06-02 | 2004-12-21 | Compositions and methods for the diagnosis and treatment of tumor |
US11/021,330 US20050159588A1 (en) | 1999-06-02 | 2004-12-21 | Compositions and methods for the diagnosis and treatment of tumor |
US11/025,607 US20050181478A1 (en) | 1998-09-01 | 2004-12-28 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US11/100,159 US7425613B2 (en) | 1997-11-05 | 2005-04-05 | PRO1375 polypeptides |
JP2005229454A JP4145314B2 (en) | 1999-06-02 | 2005-08-08 | Compositions and methods for tumor cell growth inhibition |
JP2005264293A JP2006068016A (en) | 1999-12-01 | 2005-08-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US11/341,175 US7468427B2 (en) | 1997-03-31 | 2006-01-27 | Antibodies to PRO1275 polypeptide |
JP2006225772A JP2007029098A (en) | 1999-06-02 | 2006-08-22 | Method and composition for inhibiting neoplastic cell growth |
JP2006225770A JP4072181B2 (en) | 1999-06-02 | 2006-08-22 | Compositions and methods for tumor cell growth inhibition |
JP2006225771A JP4074645B2 (en) | 1999-06-02 | 2006-08-22 | Compositions and methods for tumor cell growth inhibition |
JP2007083124A JP2007238619A (en) | 2000-01-06 | 2007-03-27 | Composition and method for inhibiting growth of tumorous cell |
US11/786,466 US20080182275A1 (en) | 1998-12-22 | 2007-04-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US11/796,725 US20090197301A1 (en) | 1998-09-01 | 2007-04-27 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
JP2007172879A JP5512073B2 (en) | 1999-06-02 | 2007-06-29 | Medicament containing polypeptide |
JP2007326609A JP2008148701A (en) | 1999-12-01 | 2007-12-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
JP2007326613A JP2008161190A (en) | 1999-12-01 | 2007-12-18 | Secreted and transmembrane polypeptide and nucleic acid encoding the same |
JP2007325484A JP2008148699A (en) | 1999-12-01 | 2007-12-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
JP2007326424A JP2008167749A (en) | 1999-12-01 | 2007-12-18 | Secreted and transmembrane polypeptide and nucleic acid encoding the same |
JP2008145176A JP2009019032A (en) | 1999-06-02 | 2008-06-02 | Promotion or inhibition of angiogenesis and cardiovascularization |
JP2011138276A JP2011236224A (en) | 1999-06-02 | 2011-06-22 | Medicine containing polypeptide |
Applications Claiming Priority (16)
Application Number | Priority Date | Filing Date | Title |
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USPCT/US99/05028 | 1999-03-08 | ||
PCT/US1999/005028 WO1999046281A2 (en) | 1998-03-10 | 1999-03-08 | Novel polypeptides and nucleic acids encoding the same |
PCT/US1999/012252 WO1999063088A2 (en) | 1998-06-02 | 1999-06-02 | Membrane-bound proteins and nucleic acids encoding the same |
USPCT/US99/12252 | 1999-06-02 | ||
US14103799P | 1999-06-23 | 1999-06-23 | |
US60/141,037 | 1999-06-23 | ||
US14304899P | 1999-07-07 | 1999-07-07 | |
US60/143,048 | 1999-07-07 | ||
US14569899P | 1999-07-26 | 1999-07-26 | |
US60/145,698 | 1999-07-26 | ||
USPCT/US99/28313 | 1999-11-30 | ||
PCT/US1999/028313 WO2000032221A2 (en) | 1998-12-01 | 1999-11-30 | Promotion or inhibition of angiogenesis and cardiovascularization |
USPCT/US99/30911 | 1999-12-20 | ||
PCT/US1999/030911 WO2000075316A1 (en) | 1999-06-02 | 1999-12-20 | Methods and compositions for inhibiting neoplastic cell growth |
PCT/US2000/000219 WO2000053753A2 (en) | 1999-03-08 | 2000-01-05 | Promotion or inhibition of angiogenesis and cardiovascularization |
USPCT/US00/00219 | 2000-01-05 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/US2000/000219 Continuation-In-Part WO2000053753A2 (en) | 1994-09-08 | 2000-01-05 | Promotion or inhibition of angiogenesis and cardiovascularization |
Related Child Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/003565 Continuation-In-Part WO2001053486A1 (en) | 1994-09-08 | 2000-02-11 | Compositions and methods for the treatment of tumor |
US87203501A Continuation-In-Part | 1996-11-06 | 2001-06-01 | |
US10/081,056 Continuation US20040043927A1 (en) | 1997-09-19 | 2002-02-20 | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
US10/119,480 Continuation US20040087769A1 (en) | 1998-09-10 | 2002-04-09 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/197,942 Continuation US20030175882A1 (en) | 1998-03-27 | 2002-07-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
Publications (2)
Publication Number | Publication Date |
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WO2000053755A2 WO2000053755A2 (en) | 2000-09-14 |
WO2000053755A3 true WO2000053755A3 (en) | 2001-02-08 |
Family
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Family Applications (1)
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PCT/US2000/000376 WO2000053755A2 (en) | 1996-11-06 | 2000-01-06 | Compositions and methods for the treatment of tumor |
Country Status (2)
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AU (1) | AU2495200A (en) |
WO (1) | WO2000053755A2 (en) |
Families Citing this family (32)
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CN1247567A (en) | 1997-01-14 | 2000-03-15 | 人体基因组科学有限公司 | Tumor necrosis factor receptor alfa 6 and receptor beta 6 |
US7285267B2 (en) | 1997-01-14 | 2007-10-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α & 6β |
US7053190B2 (en) | 1997-03-07 | 2006-05-30 | Human Genome Sciences, Inc. | Secreted protein HRGDF73 |
US6242419B1 (en) * | 1999-03-25 | 2001-06-05 | Genesis Research & Development Corporation Ltd. | Compositions isolated from stromal cells and methods for their use |
US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
AU1915201A (en) * | 1999-12-07 | 2001-06-18 | Eli Lilly And Company | Improving stability of flint through o-linked glycosylation |
EP1244784A2 (en) * | 2000-01-06 | 2002-10-02 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
GB0004576D0 (en) * | 2000-02-25 | 2000-04-19 | Oxford Glycosciences Uk Ltd | Proteins |
US20040141974A1 (en) * | 2000-02-25 | 2004-07-22 | Boyd Robert Simon | Diagnostic and therapeutic methods |
AU4884001A (en) | 2000-04-21 | 2001-11-07 | Fuso Pharmaceutical Ind | Novel collectins |
EP1666492A1 (en) * | 2000-06-02 | 2006-06-07 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WO2002055533A2 (en) * | 2000-11-22 | 2002-07-18 | Immunex Corporation | Methods of using imxp-888 and imxp-888 antagonists |
AU2005235635B2 (en) | 2004-04-21 | 2010-11-18 | Alexion Pharmaceuticals, Inc. | Bone delivery conjugates and method of using same to target proteins to bone |
BRPI0906404B8 (en) | 2008-01-24 | 2021-05-25 | Univ Louisiana State | construction of lytic domain fusion, its uses, pharmaceutical composition, as well as a process to selectively reduce or inhibit the proliferation of a cell expressing a receptor, ligand or antigen |
EP2213686A1 (en) * | 2009-01-28 | 2010-08-04 | Externautics S.p.A. | Tumor markers and methods of use thereof |
AU2011350066A1 (en) | 2010-12-27 | 2013-07-11 | Alexion Pharma International Sarl | Compositions comprising natriuretic peptides and methods of use thereof |
US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
EP4035685A1 (en) | 2012-10-30 | 2022-08-03 | Esperance Pharmaceuticals, Inc. | Antibody/drug conjugates and methods of use |
WO2016007873A1 (en) | 2014-07-11 | 2016-01-14 | The Regents Of The University Of Michigan | Compositions and methods for treating craniosynostosis |
JP6787894B2 (en) | 2014-12-05 | 2020-11-18 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | Treatment of seizures with recombinant alkaline phosphatase |
JP6868561B2 (en) | 2015-01-28 | 2021-05-12 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | How to treat subjects with alkaline phosphatase deficiency |
US11352612B2 (en) | 2015-08-17 | 2022-06-07 | Alexion Pharmaceuticals, Inc. | Manufacturing of alkaline phosphatases |
EP3355904A4 (en) | 2015-09-28 | 2019-06-12 | Alexion Pharmaceuticals, Inc. | Identifying effective dosage regimens for tissue non-specific alkaline phosphatase (tnsalp)-enzyme replacement therapy of hypophosphatasia |
US11400140B2 (en) | 2015-10-30 | 2022-08-02 | Alexion Pharmaceuticals, Inc. | Methods for treating craniosynostosis in a patient |
WO2017155569A1 (en) | 2016-03-08 | 2017-09-14 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in children |
EP3436020A4 (en) | 2016-04-01 | 2019-12-25 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in adolescents and adults |
JP2019513711A (en) | 2016-04-01 | 2019-05-30 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | Treating muscle weakness with alkaline phosphatase |
EP3452021B1 (en) * | 2016-05-06 | 2021-12-29 | Phasebio Pharmaceuticals, Inc. | Elp fusion proteins for controlled and sustained release |
WO2017214130A1 (en) | 2016-06-06 | 2017-12-14 | Alexion Pharmaceuticals, Inc. | Metal impact on manufacturing of alkaline phosphatases |
US11116821B2 (en) | 2016-08-18 | 2021-09-14 | Alexion Pharmaceuticals, Inc. | Methods for treating tracheobronchomalacia |
AU2018243320A1 (en) | 2017-03-31 | 2019-10-10 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia (HPP) in adults and adolescents |
WO2019190752A1 (en) | 2018-03-30 | 2019-10-03 | Alexion Pharmaceuticals, Inc. | Manufacturing of glycoproteins |
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