ATE444307T1 - Muteine des fibroblasten-wachstumsfaktors 21 - Google Patents

Muteine des fibroblasten-wachstumsfaktors 21

Info

Publication number
ATE444307T1
ATE444307T1 AT05775749T AT05775749T ATE444307T1 AT E444307 T1 ATE444307 T1 AT E444307T1 AT 05775749 T AT05775749 T AT 05775749T AT 05775749 T AT05775749 T AT 05775749T AT E444307 T1 ATE444307 T1 AT E444307T1
Authority
AT
Austria
Prior art keywords
muteins
growth factor
fibroblast growth
muteine
nucleic acid
Prior art date
Application number
AT05775749T
Other languages
English (en)
Inventor
Christopher Frye
Lihua Huang
Radmila Micanovic
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE444307T1 publication Critical patent/ATE444307T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT05775749T 2004-09-02 2005-07-26 Muteine des fibroblasten-wachstumsfaktors 21 ATE444307T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60680504P 2004-09-02 2004-09-02
PCT/US2005/026398 WO2006028595A2 (en) 2004-09-02 2005-07-26 Muteins of fibroblast growth factor 21

Publications (1)

Publication Number Publication Date
ATE444307T1 true ATE444307T1 (de) 2009-10-15

Family

ID=36036790

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05775749T ATE444307T1 (de) 2004-09-02 2005-07-26 Muteine des fibroblasten-wachstumsfaktors 21

Country Status (21)

Country Link
US (1) US7582607B2 (de)
EP (2) EP1789442B1 (de)
JP (1) JP4809352B2 (de)
KR (1) KR100854198B1 (de)
CN (1) CN101010338B (de)
AT (1) ATE444307T1 (de)
AU (1) AU2005283025B2 (de)
BR (1) BRPI0514790A (de)
CA (1) CA2575753A1 (de)
DE (1) DE602005016946D1 (de)
DK (1) DK1789442T3 (de)
EA (1) EA011390B1 (de)
ES (1) ES2332057T3 (de)
HR (1) HRP20090597T1 (de)
IL (1) IL181573A0 (de)
MX (1) MX2007002616A (de)
NO (1) NO20071327L (de)
PL (1) PL1789442T3 (de)
PT (1) PT1789442E (de)
SI (1) SI1789442T1 (de)
WO (1) WO2006028595A2 (de)

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Also Published As

Publication number Publication date
MX2007002616A (es) 2007-05-16
DK1789442T3 (da) 2009-11-16
US20080103096A1 (en) 2008-05-01
BRPI0514790A (pt) 2008-06-24
JP2008511323A (ja) 2008-04-17
IL181573A0 (en) 2007-07-04
AU2005283025B2 (en) 2011-06-30
US7582607B2 (en) 2009-09-01
NO20071327L (no) 2007-05-29
EP1789442B1 (de) 2009-09-30
EP1789442A2 (de) 2007-05-30
EA200700533A1 (ru) 2007-08-31
KR20070050454A (ko) 2007-05-15
SI1789442T1 (sl) 2010-01-29
EP2161281A1 (de) 2010-03-10
PL1789442T3 (pl) 2010-02-26
ES2332057T3 (es) 2010-01-25
WO2006028595A3 (en) 2007-01-18
CN101010338B (zh) 2011-06-15
KR100854198B1 (ko) 2008-08-26
PT1789442E (pt) 2009-11-11
JP4809352B2 (ja) 2011-11-09
HRP20090597T1 (hr) 2009-12-31
DE602005016946D1 (de) 2009-11-12
AU2005283025A1 (en) 2006-03-16
CN101010338A (zh) 2007-08-01
WO2006028595A2 (en) 2006-03-16
CA2575753A1 (en) 2006-03-16
EA011390B1 (ru) 2009-02-27

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