MEP22708A - Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them - Google Patents

Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them

Info

Publication number
MEP22708A
MEP22708A MEP-227/08A MEP22708A MEP22708A ME P22708 A MEP22708 A ME P22708A ME P22708 A MEP22708 A ME P22708A ME P22708 A MEP22708 A ME P22708A
Authority
ME
Montenegro
Prior art keywords
nadh
solid oral
oral compositions
compositions based
calcium
Prior art date
Application number
MEP-227/08A
Other languages
Bosnian (bs)
English (en)
Inventor
Daniele Giovannone
Angelis Carlo De
Original Assignee
Gnosis Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gnosis Spa filed Critical Gnosis Spa
Publication of MEP22708A publication Critical patent/MEP22708A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/282Organic compounds, e.g. fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
MEP-227/08A 2006-03-31 2006-08-08 Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them MEP22708A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000629A ITMI20060629A1 (it) 2006-03-31 2006-03-31 Composizioni solide orali a base di s-adenosilmetionina e processo per il loro ottenimento
PCT/IT2006/000610 WO2007113885A2 (en) 2006-03-31 2006-08-08 Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them

Publications (1)

Publication Number Publication Date
MEP22708A true MEP22708A (en) 2010-06-10

Family

ID=37327762

Family Applications (2)

Application Number Title Priority Date Filing Date
MEP-227/08A MEP22708A (en) 2006-03-31 2006-08-08 Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them
MEP-2008-227A ME00115B (me) 2006-03-31 2006-08-08 Čvrste oralne kompozicije bazirane na s-adezonil metionin i/ili nadh i proces za njihovo dobijanje

Family Applications After (1)

Application Number Title Priority Date Filing Date
MEP-2008-227A ME00115B (me) 2006-03-31 2006-08-08 Čvrste oralne kompozicije bazirane na s-adezonil metionin i/ili nadh i proces za njihovo dobijanje

Country Status (22)

Country Link
US (2) US20090110729A1 (hu)
EP (1) EP2007479B1 (hu)
JP (1) JP5562632B2 (hu)
CN (1) CN101415464B (hu)
AU (1) AU2006341243B2 (hu)
BR (1) BRPI0621556B8 (hu)
CA (1) CA2645767C (hu)
DK (1) DK2007479T3 (hu)
EA (1) EA017895B1 (hu)
ES (1) ES2774913T3 (hu)
HR (1) HRP20200315T1 (hu)
HU (1) HUE047955T2 (hu)
IL (1) IL194254A (hu)
IT (1) ITMI20060629A1 (hu)
ME (2) MEP22708A (hu)
MX (1) MX2008012491A (hu)
NZ (1) NZ571240A (hu)
PL (1) PL2007479T3 (hu)
RS (2) RS59995B1 (hu)
SI (1) SI2007479T1 (hu)
WO (1) WO2007113885A2 (hu)
ZA (1) ZA200808118B (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090088404A1 (en) * 2007-01-31 2009-04-02 Methylation Sciences International Srl Extended Release Pharmaceutical Formulations of S-Adenosylmethionine
GEP20156209B (en) 2008-08-15 2015-01-12 Aironvud Farmasiutikalz Ink Linaclotide-containing formulations for oral administration
EP2189154A1 (en) 2008-11-25 2010-05-26 Gnosis S.p.A. Effervescent tablets and mouth-soluble granulates of S-adenosyl methionine and process for the preparation thereof
IT1393331B1 (it) * 2009-02-09 2012-04-20 Graal S R L Composizioni orosolubili e/o effervescenti contenenti almeno un sale di s-adenosilmetionina (same)
WO2012012902A1 (en) * 2010-07-28 2012-02-02 Msi Methylation Sciences Inc. S-adenosylmethionine formulations with enhanced bioavailability
US20110027342A1 (en) * 2009-07-28 2011-02-03 Msi Methylation Sciences, Inc. S-adenosylmethionine formulations with enhanced bioavailability
US8329208B2 (en) * 2009-07-28 2012-12-11 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
CA2770077A1 (en) * 2009-08-06 2011-02-10 Ironwood Pharmaceuticals, Inc. Formulations comprising linaclotide
ES2638589T3 (es) 2010-02-17 2017-10-23 Ironwood Pharmaceuticals, Inc. Tratamientos para trastornos intestinales
ES2763404T3 (es) 2010-08-11 2020-05-28 Ironwood Pharmaceuticals Inc Formulaciones estables de linaclotida
EA015508B1 (ru) * 2011-03-03 2011-08-30 Екофарм Патент Менеджмент Аг Фармацевтическая композиция, стимулирующая биосинтез s-аденозилметионина, и пероральное лекарственное средство
TR201103625A1 (tr) * 2011-04-14 2012-12-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Sefuroksim içeren tablet formülasyonu üretim prosesi.
US9708371B2 (en) 2011-08-17 2017-07-18 Ironwood Pharmaceuticals, Inc. Treatments for gastrointestinal disorders
ITMI20131906A1 (it) * 2013-11-18 2015-05-19 Gnosis Spa Composizioni solide orali a lento rilascio
ES2775734T3 (es) * 2015-08-31 2020-07-28 Nutramax Lab Inc Composiciones que comprenden magnolia, felodendron, teanina y/o proteína de suero
IT202000006127A1 (it) * 2020-03-23 2021-09-23 Fmc S R L Formulazione farmaceutica, dietetica e/o alimentare a base ademetionina e processo di realizzazione di detta formulazione
CN115708820B (zh) * 2023-01-09 2023-06-02 广东科泰鼎润药业科技有限公司 L-茶氨酸缓释制剂、双释放制剂、应用和药物

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3012943A (en) * 1958-11-18 1961-12-12 Nutrilite Products Vitamin c concentrate
US3330729A (en) * 1963-10-04 1967-07-11 Goodrich Co B F Sustained release tablet containing medicament admixed in a waterinsoluble acrylic acid cross-linked polymer and selected basic magnesium or calcium diluent
IE37913B1 (en) * 1972-08-02 1977-11-09 Bioresearch Sas Salt of s-adenosyl-l-methionine
IE39517B1 (en) * 1973-06-27 1978-10-25 Bioresearch Sas Double salts of s-adenosyl-l-methhionine
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
CA1187388A (en) * 1978-09-20 1985-05-21 American Monitor Corporation Stabilization of working reagent solutions containing nadh, nadph, and/or enzymes, and the use of such stabilized reagents in enzymes or substrate assays
GB2064523B (en) * 1979-12-04 1983-06-29 Kanegafuchi Chemical Ind Stable composition of s-adenosyl-l-methionine
US4394449A (en) * 1980-02-13 1983-07-19 Modrovich Ivan Endre Stabilization of coenzymes in aqueous solution
IT1137640B (it) * 1981-08-24 1986-09-10 Bioresearch Srl Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
IT1139974B (it) * 1981-09-11 1986-09-24 Bioresearch Srl Derivati della s-adenosilmetionina,processo per la preparazione e composizioni terapeutiche che li contengono come principio attivo
JPS60181095A (ja) * 1984-02-27 1985-09-14 Nippon Zeon Co Ltd S−アデノシル−l−メチオニン含有組成物及びその製造法
IT1173991B (it) * 1984-05-16 1987-06-24 Bioresearch Spa Composizioni farmaceutiche comprendenti solfo-afenosil-l-metionina (same) particolarmente adatte per uso orale e per supposte
IT1173990B (it) * 1984-05-16 1987-06-24 Bioresearch Spa Sali stabili della solfo-adenosil-l-metionina (same) particolarmente adatti per uso parenterale
US4870059A (en) * 1985-11-27 1989-09-26 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Dehydration of hydrous matter with anhydrous maltose
US4704365A (en) * 1986-02-24 1987-11-03 Abbott Laboratories Composition and method for stabilization of dinucleotides
JPH0291018A (ja) * 1988-09-27 1990-03-30 Farval Ag 湿気に対して安定な固形バルプロ酸製剤とその製造法
US6451341B1 (en) * 1990-02-05 2002-09-17 Thomas J. Slaga Time release formulation of vitamins, minerals and other beneficial supplements
IT1243859B (it) * 1990-10-23 1994-06-28 Bioresearch Spa Composizioni farmaceutiche comprendenti associazioni fra sali di s-adenosil-l-metionina e acido 5-metil (o 5-formil)-tetraidrofolico per la terapia di complicanze neurologiche negli ammalati di aids.
US5332727A (en) * 1993-04-29 1994-07-26 Birkmayer U.S.A. Stable, ingestable and absorbable NADH and NADPH therapeutic compositions
GB2341798B (en) * 1998-09-25 2001-03-14 Brian Whittle Associates Ltd Nutritional and pharmaceutical compositions comprising desiccants
IT1318535B1 (it) * 2000-05-25 2003-08-27 Chementecno Srl Processo per la preparazione di sali farmaceuticamente accettabili di(ss,rs)-s-adenosil-l-metionina.
US20020132780A1 (en) * 2001-01-12 2002-09-19 Heisey Matthew Thomas Low carbohydrate compositions, kits thereof, and methods of use
US20030069202A1 (en) * 2000-06-02 2003-04-10 Kern Kenneth Norman Compositions, kits, and methods for promoting defined health benefits
WO2002089823A1 (fr) * 2001-04-27 2002-11-14 Kyoto Pharmaceutical Industries, Ltd. Methode de conservation pour un suppositoire
WO2002102823A1 (en) 2001-06-14 2002-12-27 Orchid Chemicals & Pharmaceuticals Limited Stable salts of s-adenosyl-l-methionine (same) and the process for their preparation
BRPI0211842B1 (pt) * 2001-08-10 2018-04-03 Hayashibara Co., Ltd. Associado cristalino compreendendo trealose e cloreto de cálcio e composição que o compreende
ITMI20012462A1 (it) * 2001-11-22 2003-05-22 Gnosis Srl Processo per la preparazione di compresse comprendenti s-adenosilmetionina
US20040131805A1 (en) * 2002-06-20 2004-07-08 Merical Rick L. Films having a desiccant material incorporated therein and methods of use and manufacture
EP1671636A4 (en) * 2003-09-22 2009-05-27 Nisshin Kyorin Pharmaceutical IMPROVED FIXED 5-AMINOSALICYLIC ACID PREPARATION AND STORAGE METHOD FOR TREATING THEREOF
EP1729766A1 (en) * 2004-03-01 2006-12-13 LEK Pharmaceuticals D.D. Pharmaceutical formulation
CN1663567A (zh) * 2004-03-05 2005-09-07 罗靖 复方甲硫氨酸维生素b1冻干粉针制剂及其制备方法
US8263574B2 (en) * 2004-09-29 2012-09-11 James L. Schaller, P.A. Topical formulations for the treatment of depression with S adenosyl methionine
ITRM20050344A1 (it) 2005-06-30 2007-01-01 Luca Maria De Sali o complessi di sostanze metil-donatrici con acido fitico o suoi derivati e relativo metodo di sintesi.
US20170312207A1 (en) * 2014-11-10 2017-11-02 Showa Denko K.K. Moisturizing agent

Also Published As

Publication number Publication date
US20090110729A1 (en) 2009-04-30
MX2008012491A (es) 2009-03-02
JP2009532344A (ja) 2009-09-10
RS59995B1 (sr) 2020-04-30
EP2007479B1 (en) 2019-12-04
NZ571240A (en) 2011-08-26
HUE047955T2 (hu) 2020-05-28
DK2007479T3 (da) 2020-02-24
EP2007479A2 (en) 2008-12-31
BRPI0621556A2 (pt) 2012-10-09
WO2007113885A3 (en) 2008-01-24
AU2006341243B2 (en) 2012-02-23
EA200802095A1 (ru) 2009-02-27
US10471088B2 (en) 2019-11-12
BRPI0621556B8 (pt) 2021-05-25
ME00115B (me) 2010-10-10
WO2007113885A8 (en) 2008-11-13
ZA200808118B (en) 2009-12-30
CN101415464B (zh) 2013-10-30
IL194254A0 (en) 2009-09-22
ITMI20060629A1 (it) 2007-10-01
CN101415464A (zh) 2009-04-22
PL2007479T3 (pl) 2020-09-21
IL194254A (en) 2015-07-30
HRP20200315T1 (hr) 2020-06-12
JP5562632B2 (ja) 2014-07-30
ES2774913T3 (es) 2020-07-23
RS20080441A (en) 2009-07-15
CA2645767A1 (en) 2007-10-11
BRPI0621556B1 (pt) 2020-09-29
CA2645767C (en) 2015-03-17
AU2006341243A1 (en) 2007-10-11
US20150306126A1 (en) 2015-10-29
WO2007113885A2 (en) 2007-10-11
SI2007479T1 (sl) 2020-04-30
EA017895B1 (ru) 2013-04-30

Similar Documents

Publication Publication Date Title
ME00115B (me) Čvrste oralne kompozicije bazirane na s-adezonil metionin i/ili nadh i proces za njihovo dobijanje
ES2628852T3 (es) Proceso para la producción de bicarbonato de sodio para desulfuración de gases de combustión
NO20074823L (no) Rasagilin-formuleringer med forbedret innholdsensartethet
ATE465719T1 (de) Oral zerfallende zusammensetzung von olanzapin oder donepezil
CO6531500A2 (es) Composiciones y metodos para el tratamiento de la xerostomia
EA201200669A1 (ru) ПИРИДОПИРИМИДИНОНОВЫЕ ИНГИБИТОРЫ PI3Kα
EA201000642A1 (ru) 2'-фтор-2'-дезокситетрагидроуридины в качестве ингибиторов цитидиндеаминазы
DE602007005024D1 (de) Verfahren zur herstellung von konzentrierten tensidzusammensetzungen
EA200800760A1 (ru) ПИРИДОПИРИМИДИНОНОВЫЕ ИНГИБИТОРЫ PI3Kα
NO20084923L (no) N-(2-thiazolyl)-amid derivater som GSK-3 inhibitorer
MX2009005768A (es) Proceso para producir condimento.
GT200900060A (es) Procedimiento de preparación de halogenuros de n-alquil-naltrexona
HN2011001446A (es) Compuesto utiles para inhibir chk1
EA201692207A1 (ru) Способ очистки технической фосфорной кислоты (например, кислоты mga) прибавлением золы из установки для сжигания отходов, включающий получение чистой фосфорной кислоты, сульфата кальция, водорастворимых гидрофосфатов кальция и раствора солей металлов
NO20083413L (no) Sammensetninger inneholdende ammoniumnitrat dobbeltsalt
MY157782A (en) Compositions and methods for the treatment of xerostomia
BRPI0911907B8 (pt) processo para produzir uma composição contendo triptofano e composição proteica contendo triptofano
EA200970377A1 (ru) Композиции фенилалкиламинокарбамата
BRPI0909195A2 (pt) Composição pulverolenta de maltitol cristalino, que não se aglomera e que se caracteriza por uma fluidez elevada
EA201890193A1 (ru) Композиция для ухода за полостью рта
MX2009012170A (es) Tinte de concreto basado en acido debil.
EA200701817A1 (ru) Новые соли 6-гетероциклических замещенных производных гексагидрофенантридина
EA200970378A1 (ru) Композиции фенилалкилкарбамата
BRPI0720050A2 (pt) 6-oxo-1,6-diidropirimidin-2-ilas no tratamento de doenças proliferativas
MX2016000796A (es) Composiciones de cemento portland de fraguado rapido con citratos fosfatos de metal alcalino y con alta resistencia a la compresion en fase inicial y contraccion reducida.