IT1393331B1 - Composizioni orosolubili e/o effervescenti contenenti almeno un sale di s-adenosilmetionina (same) - Google Patents

Composizioni orosolubili e/o effervescenti contenenti almeno un sale di s-adenosilmetionina (same)

Info

Publication number
IT1393331B1
IT1393331B1 ITMI2009A000162A ITMI20090162A IT1393331B1 IT 1393331 B1 IT1393331 B1 IT 1393331B1 IT MI2009A000162 A ITMI2009A000162 A IT MI2009A000162A IT MI20090162 A ITMI20090162 A IT MI20090162A IT 1393331 B1 IT1393331 B1 IT 1393331B1
Authority
IT
Italy
Prior art keywords
adenosilmetionine
oro
soluble
salt
same
Prior art date
Application number
ITMI2009A000162A
Other languages
English (en)
Inventor
Alessandro Seneci
Original Assignee
Graal S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ITMI2009A000162A priority Critical patent/IT1393331B1/it
Application filed by Graal S R L filed Critical Graal S R L
Priority to PCT/IB2010/050087 priority patent/WO2010089674A1/en
Priority to RU2011137151/15A priority patent/RU2524645C2/ru
Priority to BRPI1008213A priority patent/BRPI1008213A2/pt
Priority to US13/147,883 priority patent/US10149821B2/en
Priority to AU2010212042A priority patent/AU2010212042A1/en
Priority to DK10703355.7T priority patent/DK2393475T3/en
Priority to PT107033557T priority patent/PT2393475E/pt
Priority to ES10703355.7T priority patent/ES2539310T3/es
Priority to EP10703355.7A priority patent/EP2393475B1/en
Priority to CA2752009A priority patent/CA2752009C/en
Priority to PL10703355T priority patent/PL2393475T3/pl
Publication of ITMI20090162A1 publication Critical patent/ITMI20090162A1/it
Priority to IL213817A priority patent/IL213817A0/en
Application granted granted Critical
Publication of IT1393331B1 publication Critical patent/IT1393331B1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
ITMI2009A000162A 2009-02-09 2009-02-09 Composizioni orosolubili e/o effervescenti contenenti almeno un sale di s-adenosilmetionina (same) IT1393331B1 (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
ITMI2009A000162A IT1393331B1 (it) 2009-02-09 2009-02-09 Composizioni orosolubili e/o effervescenti contenenti almeno un sale di s-adenosilmetionina (same)
ES10703355.7T ES2539310T3 (es) 2009-02-09 2010-01-11 Composiciones bucosolubles que contienen al menos una sal de S-adenosilmetionina (SAMe)
BRPI1008213A BRPI1008213A2 (pt) 2009-02-09 2010-01-11 composições efervecentes e/ou solúveis por via oral contendo pelo menos um sal de s-adenosil metionina(same)
US13/147,883 US10149821B2 (en) 2009-02-09 2010-01-11 Orosoluble and/or effervescent compositions containing at least a salt of S-adenosyl methionine (SAMe)
AU2010212042A AU2010212042A1 (en) 2009-02-09 2010-01-11 Orosoluble and/or effervescent compositions containing at least a salt of s- adenosyl methionine (same)
DK10703355.7T DK2393475T3 (en) 2009-02-09 2010-01-11 ORAL SOLUBLE COMPOSITIONS CONTAINING AT LEAST ONE SALT OF S-ADENOSYLMETHIONINE (SAME)
PCT/IB2010/050087 WO2010089674A1 (en) 2009-02-09 2010-01-11 Orosoluble and/or effervescent compositions containing at least a salt of s- adenosyl methionine (same)
RU2011137151/15A RU2524645C2 (ru) 2009-02-09 2010-01-11 Растворимые во рту и/или шипучие композиции, содержащие по меньшей мере один s-аденозилметионин (sam)
EP10703355.7A EP2393475B1 (en) 2009-02-09 2010-01-11 Orosoluble compositions containing at least a salt of s- adenosyl methionine (same)
CA2752009A CA2752009C (en) 2009-02-09 2010-01-11 Orosoluble and/or effervescent compositions containing at least a salt of s-adenosyl methionine (same)
PL10703355T PL2393475T3 (pl) 2009-02-09 2010-01-11 Rozpuszczalne w jamie ustnej kompozycje zawierające przynajmniej sól s-adenozylometionina (SAMe)
PT107033557T PT2393475E (pt) 2009-02-09 2010-01-11 Composições solúveis oralmente que contêm pelo menos um sal de s-adenosilmetionina (same)
IL213817A IL213817A0 (en) 2009-02-09 2011-06-28 Orosoluble and/or effervescent compositions containing at least a salt of s-adenosyl methionine (same)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2009A000162A IT1393331B1 (it) 2009-02-09 2009-02-09 Composizioni orosolubili e/o effervescenti contenenti almeno un sale di s-adenosilmetionina (same)

Publications (2)

Publication Number Publication Date
ITMI20090162A1 ITMI20090162A1 (it) 2010-08-10
IT1393331B1 true IT1393331B1 (it) 2012-04-20

Family

ID=40995758

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI2009A000162A IT1393331B1 (it) 2009-02-09 2009-02-09 Composizioni orosolubili e/o effervescenti contenenti almeno un sale di s-adenosilmetionina (same)

Country Status (13)

Country Link
US (1) US10149821B2 (it)
EP (1) EP2393475B1 (it)
AU (1) AU2010212042A1 (it)
BR (1) BRPI1008213A2 (it)
CA (1) CA2752009C (it)
DK (1) DK2393475T3 (it)
ES (1) ES2539310T3 (it)
IL (1) IL213817A0 (it)
IT (1) IT1393331B1 (it)
PL (1) PL2393475T3 (it)
PT (1) PT2393475E (it)
RU (1) RU2524645C2 (it)
WO (1) WO2010089674A1 (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2963239B1 (fr) * 2010-08-02 2013-03-08 Vetalis Formes galeniques effervescentes solides pour animaux
WO2013024663A1 (ja) 2011-08-12 2013-02-21 三菱瓦斯化学株式会社 保存安定性に優れたs-アデノシル-l-メチオニン含有組成物
US8877259B2 (en) 2012-02-09 2014-11-04 Mary Kay Inc. Cosmetic formulation
CN104418928B (zh) * 2013-08-27 2017-03-29 上海医药工业研究院 一种1,4‑丁二磺酸腺苷蛋氨酸的制备方法
US9351921B1 (en) * 2013-09-10 2016-05-31 Spa De Soleil, Inc. Microdermabrasion cream
AT14825U1 (de) * 2014-11-10 2016-07-15 Eduard Rappold Kombinationspräparat enthaltend Ademetionin und Vitamin B12 zur Behandlung und Prävention der Alzheimer-Krankheit Typ I (LOAD)
ES2586632B1 (es) * 2015-01-29 2017-09-05 Wug Functional Gums, S.L Composición para elaborar chicles
US9446100B2 (en) 2015-02-13 2016-09-20 Eastern Vision Limited Dietary supplements and formulations
CN104983026A (zh) * 2015-07-21 2015-10-21 上海海洋大学 山楂泡腾片及其制备方法
JP6860951B2 (ja) * 2015-08-31 2021-04-21 ニュートラマックス ラボラトリーズ,インコーポレイテッド マグノリア、キハダ、テアニンおよび/または乳清タンパク質を有する組成物
RU2611411C1 (ru) * 2016-01-11 2017-02-21 Общество с ограниченной ответственностью "Трейдсервис" Диспергируемая в воде таблетка ацетилцистеина и способ ее изготовления
ITUA20163269A1 (it) 2016-05-09 2017-11-09 Graal S R L Composizione ad assorbimento orobuccale per la neuro-protezione
IT201600080839A1 (it) * 2016-08-01 2018-02-01 Esserre Pharma Srl Composizione a base di S-Adenosil-L-Metionina e Melatonina per il trattamento dei disturbi del comportamento alimentare
WO2019084540A1 (en) * 2017-10-27 2019-05-02 Zeta Biolongevity, Inc. COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING PROTEINURY AND ENDOTHELIAL EROSION
IT201900015192A1 (it) 2019-08-29 2021-03-01 Graal S R L Formulazioni edibili a base di principi attivi e arginina
CN111172043B (zh) * 2020-01-14 2021-03-05 北京工商大学 一种提高紫红曲霉中红曲色素合成的发酵方法
IT202000006127A1 (it) * 2020-03-23 2021-09-23 Fmc S R L Formulazione farmaceutica, dietetica e/o alimentare a base ademetionina e processo di realizzazione di detta formulazione
CN111297963B (zh) * 2020-04-10 2021-11-26 广东轻工职业技术学院 一种解酒护肝提取物、组合物及制备方法与应用
IT202000008482A1 (it) * 2020-04-21 2021-10-21 Montefarmaco Otc S P A Composizione orale contente s-adenosil metionina (same) e almeno un probiotico e suo uso
RU2749833C1 (ru) * 2020-08-11 2021-06-17 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет технологий и управления имени К.Г. Разумовского (ПКУ)" Способ производства диетического витаминизированного шоколада
IT202000030914A1 (it) * 2020-12-15 2022-06-15 Mario Antonio Basile Composizione farmaceutica solida di ademetionina e cannabidiolo e procedimento per ottenerla

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4057672A (en) 1973-05-29 1977-11-08 The Goodyear Tire & Rubber Company Compounded polyvinyl chloride
IE39517B1 (en) * 1973-06-27 1978-10-25 Bioresearch Sas Double salts of s-adenosyl-l-methhionine
US4432975A (en) * 1981-04-13 1984-02-21 Icn Pharmaceuticals, Inc. Process for introducing vitamin B-12 into the bloodstream
IT1137640B (it) 1981-08-24 1986-09-10 Bioresearch Srl Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
DE69727922T2 (de) * 1996-04-16 2005-01-20 Novartis Consumer Health S.A. Schnell zerfallende orale dosierungsform
BRPI0515932A (pt) * 2004-10-15 2008-08-12 Pfizer Prod Inc composições e métodos para distribuição intranasal, bucal, sublingual e pulmonar de vareniclina
US20060127506A1 (en) * 2004-12-10 2006-06-15 Hebert Rolland F Compositions of S-adenosyl-L-methionine
US20060198885A1 (en) * 2005-02-22 2006-09-07 Sun Pharmaceutical Industries Ltd. Oral pharmaceutical composition
ITRM20050344A1 (it) * 2005-06-30 2007-01-01 Luca Maria De Sali o complessi di sostanze metil-donatrici con acido fitico o suoi derivati e relativo metodo di sintesi.
ITMI20060026A1 (it) * 2006-01-10 2007-07-11 Truffini & Regge Farmaceutici Srl Composizioni per uso rale a base di s-adenosilmetionina e processo per il loro ottenimento
RU2313349C2 (ru) * 2006-01-16 2007-12-27 Михаил Аркадьевич Шурдов Способ лечения онкологических заболеваний
ITMI20060629A1 (it) * 2006-03-31 2007-10-01 Daniele Giovannone Composizioni solide orali a base di s-adenosilmetionina e processo per il loro ottenimento
US8597640B2 (en) * 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
EP2189154A1 (en) * 2008-11-25 2010-05-26 Gnosis S.p.A. Effervescent tablets and mouth-soluble granulates of S-adenosyl methionine and process for the preparation thereof
EP2193787A1 (en) * 2008-12-02 2010-06-09 Giorgio Stramentinoli Formulations for systemic buccal delivery comprising s-adenosylmethionine, their preparation and use

Also Published As

Publication number Publication date
BRPI1008213A2 (pt) 2016-03-15
CA2752009A1 (en) 2010-08-12
RU2011137151A (ru) 2013-03-20
PL2393475T3 (pl) 2015-08-31
EP2393475B1 (en) 2015-03-11
DK2393475T3 (en) 2015-06-15
WO2010089674A1 (en) 2010-08-12
PT2393475E (pt) 2015-07-17
CA2752009C (en) 2016-09-27
US10149821B2 (en) 2018-12-11
US20110300081A1 (en) 2011-12-08
ITMI20090162A1 (it) 2010-08-10
IL213817A0 (en) 2011-07-31
AU2010212042A1 (en) 2011-07-21
ES2539310T3 (es) 2015-06-29
AU2010212042A2 (en) 2011-08-18
RU2524645C2 (ru) 2014-07-27
EP2393475A1 (en) 2011-12-14

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