EA200802095A1 - ТВЕРДЫЕ ПРИНИМАЕМЫЕ ВНУТРЬ ЛЕКАРСТВЕННЫЕ КОМПОЗИЦИИ НА ОСНОВЕ S-АДЕНОЗИЛМЕТИОНИНА (SAMe) И/ИЛИ НИКОТИНАМИДАДЕНИНДИНУКЛЕОТИДА (NADH) И СПОСОБ ИХ ПОЛУЧЕНИЯ - Google Patents

ТВЕРДЫЕ ПРИНИМАЕМЫЕ ВНУТРЬ ЛЕКАРСТВЕННЫЕ КОМПОЗИЦИИ НА ОСНОВЕ S-АДЕНОЗИЛМЕТИОНИНА (SAMe) И/ИЛИ НИКОТИНАМИДАДЕНИНДИНУКЛЕОТИДА (NADH) И СПОСОБ ИХ ПОЛУЧЕНИЯ

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Publication number
EA200802095A1
EA200802095A1 EA200802095A EA200802095A EA200802095A1 EA 200802095 A1 EA200802095 A1 EA 200802095A1 EA 200802095 A EA200802095 A EA 200802095A EA 200802095 A EA200802095 A EA 200802095A EA 200802095 A1 EA200802095 A1 EA 200802095A1
Authority
EA
Eurasian Patent Office
Prior art keywords
same
nadh
compositions based
calcium
solid
Prior art date
Application number
EA200802095A
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English (en)
Other versions
EA017895B1 (ru
Inventor
Даниэле Джованноне
Карло Де Анжелис
Original Assignee
Гносис Спа
Даниэле Джованноне
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Гносис Спа, Даниэле Джованноне filed Critical Гносис Спа
Publication of EA200802095A1 publication Critical patent/EA200802095A1/ru
Publication of EA017895B1 publication Critical patent/EA017895B1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)

Abstract

Данное изобретение относится к твердым принимаемым внутрь композициям на основе S-аденозилметионина (SAMe) или восстановленного никотинамидадениндинуклеотида (NADH) в сочетании с окисью кальция и/или гидроокисью кальция и к способу их получения. Данное изобретение относится также к способу стабилизации твердой принимаемой внутрь композиции на основе SAMe и/или NADH или их солей путем использования окиси кальция и гидроокиси кальция необязательно в сочетании с яблочной кислотой, глутаминовой кислотой, ксилитом, полугидратом сульфата кальция, окисью магния и/или их смесями. Данное изобретение также относится к использованию SAMe или его солей совместно с окисью кальция и/или гидроокисью кальция с возможной добавкой мелатонина, и/или 1-теанина, и/или 1-триптофана, и/или 5-гидрокситриптофана для лечения депрессивных состояний.
EA200802095A 2006-03-31 2006-08-08 ТВЕРДЫЕ ПРИНИМАЕМЫЕ ВНУТРЬ ЛЕКАРСТВЕННЫЕ КОМПОЗИЦИИ НА ОСНОВЕ S-АДЕНОЗИЛМЕТИОНИНА (SAMe) ИЛИ НИКОТИНАМИДАДЕНИНДИНУКЛЕОТИДА (NADH) И СПОСОБ ИХ ПОЛУЧЕНИЯ EA017895B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000629A ITMI20060629A1 (it) 2006-03-31 2006-03-31 Composizioni solide orali a base di s-adenosilmetionina e processo per il loro ottenimento
PCT/IT2006/000610 WO2007113885A2 (en) 2006-03-31 2006-08-08 Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them

Publications (2)

Publication Number Publication Date
EA200802095A1 true EA200802095A1 (ru) 2009-02-27
EA017895B1 EA017895B1 (ru) 2013-04-30

Family

ID=37327762

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200802095A EA017895B1 (ru) 2006-03-31 2006-08-08 ТВЕРДЫЕ ПРИНИМАЕМЫЕ ВНУТРЬ ЛЕКАРСТВЕННЫЕ КОМПОЗИЦИИ НА ОСНОВЕ S-АДЕНОЗИЛМЕТИОНИНА (SAMe) ИЛИ НИКОТИНАМИДАДЕНИНДИНУКЛЕОТИДА (NADH) И СПОСОБ ИХ ПОЛУЧЕНИЯ

Country Status (22)

Country Link
US (2) US20090110729A1 (ru)
EP (1) EP2007479B1 (ru)
JP (1) JP5562632B2 (ru)
CN (1) CN101415464B (ru)
AU (1) AU2006341243B2 (ru)
BR (1) BRPI0621556B8 (ru)
CA (1) CA2645767C (ru)
DK (1) DK2007479T3 (ru)
EA (1) EA017895B1 (ru)
ES (1) ES2774913T3 (ru)
HR (1) HRP20200315T1 (ru)
HU (1) HUE047955T2 (ru)
IL (1) IL194254A (ru)
IT (1) ITMI20060629A1 (ru)
ME (2) MEP22708A (ru)
MX (1) MX2008012491A (ru)
NZ (1) NZ571240A (ru)
PL (1) PL2007479T3 (ru)
RS (2) RS20080441A (ru)
SI (1) SI2007479T1 (ru)
WO (1) WO2007113885A2 (ru)
ZA (1) ZA200808118B (ru)

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ES2775734T3 (es) * 2015-08-31 2020-07-28 Nutramax Lab Inc Composiciones que comprenden magnolia, felodendron, teanina y/o proteína de suero
IT202000006127A1 (it) * 2020-03-23 2021-09-23 Fmc S R L Formulazione farmaceutica, dietetica e/o alimentare a base ademetionina e processo di realizzazione di detta formulazione
CN115708820B (zh) * 2023-01-09 2023-06-02 广东科泰鼎润药业科技有限公司 L-茶氨酸缓释制剂、双释放制剂、应用和药物

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Also Published As

Publication number Publication date
CN101415464B (zh) 2013-10-30
AU2006341243B2 (en) 2012-02-23
CN101415464A (zh) 2009-04-22
CA2645767A1 (en) 2007-10-11
US20090110729A1 (en) 2009-04-30
EA017895B1 (ru) 2013-04-30
DK2007479T3 (da) 2020-02-24
ZA200808118B (en) 2009-12-30
JP2009532344A (ja) 2009-09-10
MX2008012491A (es) 2009-03-02
US10471088B2 (en) 2019-11-12
WO2007113885A2 (en) 2007-10-11
ME00115B (me) 2010-10-10
IL194254A (en) 2015-07-30
MEP22708A (en) 2010-06-10
SI2007479T1 (sl) 2020-04-30
EP2007479A2 (en) 2008-12-31
BRPI0621556B8 (pt) 2021-05-25
HUE047955T2 (hu) 2020-05-28
CA2645767C (en) 2015-03-17
ES2774913T3 (es) 2020-07-23
WO2007113885A8 (en) 2008-11-13
JP5562632B2 (ja) 2014-07-30
ITMI20060629A1 (it) 2007-10-01
RS59995B1 (sr) 2020-04-30
PL2007479T3 (pl) 2020-09-21
HRP20200315T1 (hr) 2020-06-12
WO2007113885A3 (en) 2008-01-24
IL194254A0 (en) 2009-09-22
EP2007479B1 (en) 2019-12-04
NZ571240A (en) 2011-08-26
US20150306126A1 (en) 2015-10-29
AU2006341243A1 (en) 2007-10-11
RS20080441A (en) 2009-07-15
BRPI0621556A2 (pt) 2012-10-09
BRPI0621556B1 (pt) 2020-09-29

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