RS20080441A - Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them - Google Patents

Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them

Info

Publication number
RS20080441A
RS20080441A RSP-2008/0441A RSP20080441A RS20080441A RS 20080441 A RS20080441 A RS 20080441A RS P20080441 A RSP20080441 A RS P20080441A RS 20080441 A RS20080441 A RS 20080441A
Authority
RS
Serbia
Prior art keywords
nadh
solid oral
obtaining
calcium
oral compositions
Prior art date
Application number
RSP-2008/0441A
Other languages
English (en)
Inventor
Daniele Giovannone
Carlo De Angelis
Original Assignee
Daniele Giovannone
Gnosis Spa.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daniele Giovannone, Gnosis Spa., filed Critical Daniele Giovannone
Publication of RS20080441A publication Critical patent/RS20080441A/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)

Abstract

Ovaj pronalazak se odnosi na čvrste oralne kompozicije bazirane na SAMe i/ili NADH ili njihovim solima zajedno sa kalcijum oksidom i/ili kalcijum hidroksidom i na proces za njihovo dobijanje.Pronalazak se takođe odnosi na postupak za stabilizaciju čvrstih oralnih kompozicija baziranih na SAMe i/ili NADH ili njihovim solima, upotrebom kalcijum oksida, kalcijum hidroksida, po izboru zajedno sa maleinskom kiselinom, glutaminskom kiselinom, ksilitolom, kalcijum sulfat hemihidratom, magnezijum oksidom i/ili njihovim smešama. Ovaj pronalazak se takođe odnosi na upotrebu SAMe ili njegovih soli zajedno sa kalcijom oksidom i/ili kalcijum hidroksidom sa mogućim dodatkom melatonina i/ili 1-teanin i/ili 1-triptofana i/ili 5-hidroksitriptofana za lečenje depresivnih stanja.
RSP-2008/0441A 2006-03-31 2006-08-08 Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them RS20080441A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000629A ITMI20060629A1 (it) 2006-03-31 2006-03-31 Composizioni solide orali a base di s-adenosilmetionina e processo per il loro ottenimento
PCT/IT2006/000610 WO2007113885A2 (en) 2006-03-31 2006-08-08 Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them

Publications (1)

Publication Number Publication Date
RS20080441A true RS20080441A (en) 2009-07-15

Family

ID=37327762

Family Applications (2)

Application Number Title Priority Date Filing Date
RS20200221A RS59995B1 (sr) 2006-03-31 2006-08-08 Čvrsti oralni preparati na bazi soli s-adenozil metionina i postupak njihovog dobijanja
RSP-2008/0441A RS20080441A (en) 2006-03-31 2006-08-08 Solid oral compositions based on s-adenosyl methionine and/or nadh and process for obtaining them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RS20200221A RS59995B1 (sr) 2006-03-31 2006-08-08 Čvrsti oralni preparati na bazi soli s-adenozil metionina i postupak njihovog dobijanja

Country Status (22)

Country Link
US (2) US20090110729A1 (sr)
EP (1) EP2007479B1 (sr)
JP (1) JP5562632B2 (sr)
CN (1) CN101415464B (sr)
AU (1) AU2006341243B2 (sr)
BR (1) BRPI0621556B8 (sr)
CA (1) CA2645767C (sr)
DK (1) DK2007479T3 (sr)
EA (1) EA017895B1 (sr)
ES (1) ES2774913T3 (sr)
HR (1) HRP20200315T1 (sr)
HU (1) HUE047955T2 (sr)
IL (1) IL194254A (sr)
IT (1) ITMI20060629A1 (sr)
ME (2) MEP22708A (sr)
MX (1) MX2008012491A (sr)
NZ (1) NZ571240A (sr)
PL (1) PL2007479T3 (sr)
RS (2) RS59995B1 (sr)
SI (1) SI2007479T1 (sr)
WO (1) WO2007113885A2 (sr)
ZA (1) ZA200808118B (sr)

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GEP20156209B (en) 2008-08-15 2015-01-12 Aironvud Farmasiutikalz Ink Linaclotide-containing formulations for oral administration
EP2189154A1 (en) 2008-11-25 2010-05-26 Gnosis S.p.A. Effervescent tablets and mouth-soluble granulates of S-adenosyl methionine and process for the preparation thereof
IT1393331B1 (it) * 2009-02-09 2012-04-20 Graal S R L Composizioni orosolubili e/o effervescenti contenenti almeno un sale di s-adenosilmetionina (same)
WO2012012902A1 (en) * 2010-07-28 2012-02-02 Msi Methylation Sciences Inc. S-adenosylmethionine formulations with enhanced bioavailability
US20110027342A1 (en) * 2009-07-28 2011-02-03 Msi Methylation Sciences, Inc. S-adenosylmethionine formulations with enhanced bioavailability
US8329208B2 (en) * 2009-07-28 2012-12-11 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
CA2770077A1 (en) * 2009-08-06 2011-02-10 Ironwood Pharmaceuticals, Inc. Formulations comprising linaclotide
ES2638589T3 (es) 2010-02-17 2017-10-23 Ironwood Pharmaceuticals, Inc. Tratamientos para trastornos intestinales
ES2763404T3 (es) 2010-08-11 2020-05-28 Ironwood Pharmaceuticals Inc Formulaciones estables de linaclotida
EA015508B1 (ru) * 2011-03-03 2011-08-30 Екофарм Патент Менеджмент Аг Фармацевтическая композиция, стимулирующая биосинтез s-аденозилметионина, и пероральное лекарственное средство
TR201103625A1 (tr) * 2011-04-14 2012-12-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Sefuroksim içeren tablet formülasyonu üretim prosesi.
US9708371B2 (en) 2011-08-17 2017-07-18 Ironwood Pharmaceuticals, Inc. Treatments for gastrointestinal disorders
ITMI20131906A1 (it) * 2013-11-18 2015-05-19 Gnosis Spa Composizioni solide orali a lento rilascio
ES2775734T3 (es) * 2015-08-31 2020-07-28 Nutramax Lab Inc Composiciones que comprenden magnolia, felodendron, teanina y/o proteína de suero
IT202000006127A1 (it) * 2020-03-23 2021-09-23 Fmc S R L Formulazione farmaceutica, dietetica e/o alimentare a base ademetionina e processo di realizzazione di detta formulazione
CN115708820B (zh) * 2023-01-09 2023-06-02 广东科泰鼎润药业科技有限公司 L-茶氨酸缓释制剂、双释放制剂、应用和药物

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Also Published As

Publication number Publication date
US20090110729A1 (en) 2009-04-30
MX2008012491A (es) 2009-03-02
JP2009532344A (ja) 2009-09-10
RS59995B1 (sr) 2020-04-30
EP2007479B1 (en) 2019-12-04
NZ571240A (en) 2011-08-26
HUE047955T2 (hu) 2020-05-28
DK2007479T3 (da) 2020-02-24
EP2007479A2 (en) 2008-12-31
BRPI0621556A2 (pt) 2012-10-09
WO2007113885A3 (en) 2008-01-24
AU2006341243B2 (en) 2012-02-23
EA200802095A1 (ru) 2009-02-27
US10471088B2 (en) 2019-11-12
BRPI0621556B8 (pt) 2021-05-25
MEP22708A (en) 2010-06-10
ME00115B (me) 2010-10-10
WO2007113885A8 (en) 2008-11-13
ZA200808118B (en) 2009-12-30
CN101415464B (zh) 2013-10-30
IL194254A0 (en) 2009-09-22
ITMI20060629A1 (it) 2007-10-01
CN101415464A (zh) 2009-04-22
PL2007479T3 (pl) 2020-09-21
IL194254A (en) 2015-07-30
HRP20200315T1 (hr) 2020-06-12
JP5562632B2 (ja) 2014-07-30
ES2774913T3 (es) 2020-07-23
CA2645767A1 (en) 2007-10-11
BRPI0621556B1 (pt) 2020-09-29
CA2645767C (en) 2015-03-17
AU2006341243A1 (en) 2007-10-11
US20150306126A1 (en) 2015-10-29
WO2007113885A2 (en) 2007-10-11
SI2007479T1 (sl) 2020-04-30
EA017895B1 (ru) 2013-04-30

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