MD970230A - Sare de diclavulanat cu diaminoeter si procedeu de preparare a ei - Google Patents

Sare de diclavulanat cu diaminoeter si procedeu de preparare a ei

Info

Publication number
MD970230A
MD970230A MD97-0230A MD970230A MD970230A MD 970230 A MD970230 A MD 970230A MD 970230 A MD970230 A MD 970230A MD 970230 A MD970230 A MD 970230A
Authority
MD
Moldova
Prior art keywords
diclavulanate
preparation
diamine ether
diamine
ether
Prior art date
Application number
MD97-0230A
Other languages
English (en)
Other versions
MD1738F2 (ro
Inventor
George Leo Callewaert
Original Assignee
Spurcourt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spurcourt Ltd filed Critical Spurcourt Ltd
Publication of MD970230A publication Critical patent/MD970230A/ro
Publication of MD1738F2 publication Critical patent/MD1738F2/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
MD97-0230A 1994-12-24 1995-12-22 Sare de diclavulanat, procedeu de obţinere şi compoziţie farmaceutică pe baza ei MD1738F2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426261.5A GB9426261D0 (en) 1994-12-24 1994-12-24 Clavulanic acid salts
PCT/GB1995/003039 WO1996020199A2 (en) 1994-12-24 1995-12-22 Diclavulanate salt with a diamino ether and process of preparation

Publications (2)

Publication Number Publication Date
MD970230A true MD970230A (ro) 1999-05-31
MD1738F2 MD1738F2 (ro) 2001-09-30

Family

ID=10766624

Family Applications (1)

Application Number Title Priority Date Filing Date
MD97-0230A MD1738F2 (ro) 1994-12-24 1995-12-22 Sare de diclavulanat, procedeu de obţinere şi compoziţie farmaceutică pe baza ei

Country Status (40)

Country Link
US (1) US5786351A (ro)
EP (1) EP0799233B1 (ro)
JP (1) JPH10511386A (ro)
KR (1) KR100416946B1 (ro)
CN (1) CN1081640C (ro)
AP (1) AP670A (ro)
AR (1) AR004165A1 (ro)
AT (1) ATE178606T1 (ro)
AU (1) AU702968B2 (ro)
BG (1) BG62971B1 (ro)
BR (1) BR9510250A (ro)
CA (1) CA2208520C (ro)
CZ (1) CZ289287B6 (ro)
DE (1) DE69508962T2 (ro)
DK (1) DK0799233T3 (ro)
EE (1) EE9700139A (ro)
ES (1) ES2132756T3 (ro)
FI (1) FI972464L (ro)
GB (1) GB9426261D0 (ro)
GE (1) GEP20002212B (ro)
GR (1) GR3030629T3 (ro)
HU (1) HUT77090A (ro)
IL (1) IL116498A (ro)
IS (1) IS4501A (ro)
MD (1) MD1738F2 (ro)
MY (1) MY114213A (ro)
NO (1) NO313200B1 (ro)
NZ (1) NZ297857A (ro)
OA (1) OA10861A (ro)
PL (1) PL182364B1 (ro)
RO (1) RO118429B1 (ro)
RU (1) RU2152948C1 (ro)
SE (1) SE520665C2 (ro)
SI (2) SI9520145A (ro)
SK (1) SK282663B6 (ro)
TJ (1) TJ269B (ro)
TR (1) TR199501675A2 (ro)
TW (1) TW401409B (ro)
WO (1) WO1996020199A2 (ro)
ZA (1) ZA9510880B (ro)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9400107A (en) 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
SI9500134B (sl) 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
WO1998021212A1 (en) * 1996-11-11 1998-05-22 Gist-Brocades B.V. Process for the preparation of salts and esters of clavulanic acid
AT404728B (de) * 1996-11-27 1999-02-25 Biochemie Gmbh Verfahren zur herstellung von clavulansäure-aminsalzen
KR100827898B1 (ko) 2000-05-13 2008-05-07 스미스클라인비이참피이엘시이 클라불란산의 염의 정제 방법
EP2276840A1 (en) * 2008-04-02 2011-01-26 DSM IP Assets B.V. Diamine salts of carboxylic acids
EP3938442A1 (de) 2019-03-15 2022-01-19 LANXESS Deutschland GmbH Hochvoltkomponenten

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144242A (en) * 1975-02-07 1979-03-13 Glaxo Laboratories Limited Process for the purification of clavulanic acid
GB1578739A (en) 1976-07-23 1980-11-05 Beecham Group Ltd Amine salts of clavulanic acid methods for their preparation and compositions containing them
US4255332A (en) * 1977-09-01 1981-03-10 Beecham Group Limited Process for the preparation of potassium clavulanate from lithium clavulanate
US4454069A (en) * 1979-08-24 1984-06-12 Beecham Group Limited Clavulanic acid salts and their preparation from the tertiary butyl amine salt
EP0026044B1 (en) * 1979-08-24 1983-06-08 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
US5288861A (en) * 1987-01-29 1994-02-22 Beecham Group Plc Potassium clavulanate in rosette form
ES2008418A6 (es) * 1987-01-29 1989-07-16 Beecham Group Plc Un procedimiento para la obtencioon de nueva forma cristalina del clavulanato de potasio y de composiciones del mismo.
ES2010143A6 (es) * 1989-03-01 1989-10-16 Pharma Mar S A Pharmar Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
AT400033B (de) * 1992-03-10 1995-09-25 Biochemie Gmbh Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
GB9305565D0 (en) * 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes
DE647229T1 (de) * 1993-03-26 1996-01-18 Gist Brocades Nv Diaminsalze von clavulansäure.
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts

Also Published As

Publication number Publication date
AU702968B2 (en) 1999-03-11
MY114213A (en) 2002-08-30
WO1996020199A3 (en) 1996-09-12
FI972464A7 (fi) 1997-08-21
SI0799233T1 (en) 1999-08-31
SK77697A3 (en) 1998-01-14
FI972464A0 (fi) 1997-06-10
CN1171111A (zh) 1998-01-21
EE9700139A (et) 1997-12-15
AU4311096A (en) 1996-07-19
CZ192097A3 (cs) 1998-08-12
US5786351A (en) 1998-07-28
MD1738F2 (ro) 2001-09-30
SK282663B6 (sk) 2002-11-06
WO1996020199A2 (en) 1996-07-04
IL116498A (en) 2000-07-26
ES2132756T3 (es) 1999-08-16
FI972464L (fi) 1997-08-21
GB9426261D0 (en) 1995-02-22
TJ269B (en) 2000-08-07
CN1081640C (zh) 2002-03-27
NO972946L (no) 1997-06-23
RU2152948C1 (ru) 2000-07-20
SI9520145A (sl) 1998-02-28
OA10861A (en) 2003-02-17
GR3030629T3 (en) 1999-10-29
DE69508962D1 (de) 1999-05-12
PL182364B1 (pl) 2001-12-31
BG62971B1 (bg) 2000-12-29
IS4501A (is) 1997-06-09
ATE178606T1 (de) 1999-04-15
DE69508962T2 (de) 1999-08-12
DK0799233T3 (da) 1999-10-18
AP670A (en) 1998-09-04
TW401409B (en) 2000-08-11
BG101671A (bg) 1998-09-30
CZ289287B6 (cs) 2001-12-12
IL116498A0 (en) 1996-03-31
KR100416946B1 (ko) 2004-05-10
SE9702306L (sv) 1997-08-25
ZA9510880B (en) 1996-08-07
SE9702306D0 (sv) 1997-06-17
AR004165A1 (es) 1998-11-04
HUT77090A (hu) 1998-03-02
EP0799233A2 (en) 1997-10-08
MX9704693A (es) 1998-06-30
NZ297857A (en) 1997-11-24
JPH10511386A (ja) 1998-11-04
SE520665C2 (sv) 2003-08-05
AP9701013A0 (en) 1997-07-31
TR199501675A2 (tr) 1997-07-21
CA2208520A1 (en) 1996-07-04
BR9510250A (pt) 1997-11-04
GEP20002212B (en) 2000-08-25
RO118429B1 (ro) 2003-05-30
PL321092A1 (en) 1997-11-24
EP0799233B1 (en) 1999-04-07
NO972946D0 (no) 1997-06-23
NO313200B1 (no) 2002-08-26
CA2208520C (en) 2003-10-07

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