MD423C2 - Procedeu de obţinere a delmopionului, compuşi intermediari pentru efectuarea procedeului - Google Patents

Procedeu de obţinere a delmopionului, compuşi intermediari pentru efectuarea procedeului

Info

Publication number
MD423C2
MD423C2 MD95-0039A MD950039A MD423C2 MD 423 C2 MD423 C2 MD 423C2 MD 950039 A MD950039 A MD 950039A MD 423 C2 MD423 C2 MD 423C2
Authority
MD
Moldova
Prior art keywords
delmopinol
realizing
preparation process
intermediate compositions
optional
Prior art date
Application number
MD95-0039A
Other languages
English (en)
Russian (ru)
Inventor
Sven Hernestam
Bernt Thelin
Elizabeth Seifert
Arne Nilsson
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8901837A external-priority patent/SE8901837D0/xx
Priority claimed from SE8901838A external-priority patent/SE8901838D0/xx
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Publication of MD423C2 publication Critical patent/MD423C2/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Luminescent Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Invenţia se referă la un procedeu nou de obţinere a delmopinolului, utilizând produsele intermediare, cu formuleleîn care R reprezintă 2-propilpentil, arbitrar cu una, două sau trei legături interne nesaturate, sau 2-propilpentil 2-substituit, arbitrar cu una sau două legături interne nesaturate, în care substituentul în poziţia 2 este grupa înlăturată.
MD95-0039A 1989-05-24 1994-07-14 Procedeu de obţinere a delmopionului, compuşi intermediari pentru efectuarea procedeului MD423C2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8901837A SE8901837D0 (sv) 1989-05-24 1989-05-24 Substituted isoxazolidines and isoxazolines
SE8901838A SE8901838D0 (sv) 1989-05-24 1989-05-24 New process and intermediates

Publications (1)

Publication Number Publication Date
MD423C2 true MD423C2 (ro) 1996-09-30

Family

ID=26660511

Family Applications (1)

Application Number Title Priority Date Filing Date
MD95-0039A MD423C2 (ro) 1989-05-24 1994-07-14 Procedeu de obţinere a delmopionului, compuşi intermediari pentru efectuarea procedeului

Country Status (26)

Country Link
US (1) US5155220A (ro)
EP (1) EP0426826B1 (ro)
JP (1) JP3042876B2 (ro)
KR (1) KR0176248B1 (ro)
CN (1) CN1039325C (ro)
AT (1) ATE104968T1 (ro)
AU (1) AU631648B2 (ro)
CA (2) CA2032513C (ro)
DD (1) DD300104A5 (ro)
DE (1) DE69008486T2 (ro)
DK (1) DK0426826T3 (ro)
ES (1) ES2053195T3 (ro)
FI (1) FI97057C (ro)
GE (1) GEP19971047B (ro)
GR (1) GR1001407B (ro)
HU (1) HU205118B (ro)
IE (1) IE65640B1 (ro)
IL (1) IL94427A (ro)
LV (1) LV10276B (ro)
MD (1) MD423C2 (ro)
NO (2) NO179870C (ro)
NZ (1) NZ233730A (ro)
PH (1) PH31619A (ro)
PT (1) PT94131B (ro)
RU (1) RU2042670C1 (ro)
WO (1) WO1990014342A1 (ro)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147632A (en) * 1990-10-31 1992-09-15 Warner-Lambert Company Anti-plaque compositions comprising a combination of morpholinoamino alcohol and chelating agent
GB9226857D0 (en) * 1992-12-23 1993-02-17 Boyd Edward A Pharmaceutical compositions
US5552757A (en) * 1994-05-27 1996-09-03 Littelfuse, Inc. Surface-mounted fuse device
US6878004B2 (en) * 2002-03-04 2005-04-12 Littelfuse, Inc. Multi-element fuse array
US7842689B2 (en) 2003-06-12 2010-11-30 Btg International Limited Cyclic hydroxylamine as psychoactive compounds
DE112004002301T5 (de) * 2003-11-26 2006-09-28 Littelfuse, Inc., Des Plaines Elektrische Schutzeinrichtung für ein Fahrzeug und System, das diese einsetzt
GB0523435D0 (en) 2005-11-17 2005-12-28 Sinclair Pharmaceuticals Ltd Process
PT1951374T (pt) 2005-11-22 2017-06-08 Merial Inc Tratamento de infeções de bolsas subgengivais
GB0602424D0 (en) 2006-02-07 2006-03-22 Sinclair Pharmaceuticals Ltd Compounds
GB0604018D0 (en) * 2006-02-28 2006-04-05 Sinclair Pharmaceuticals Ltd Method
GB0615814D0 (en) 2006-08-09 2006-09-20 Sinclair Pharmaceuticals Ltd Medicament
GB201105162D0 (en) 2011-03-28 2011-05-11 Lane Jonathan Improved deodorant formulations
IT201600130642A1 (it) 2016-12-23 2018-06-23 Lundbeck Pharmaceuticals Italy S P A Processo per la produzione di 2(3 alchilmorfolino)-etan-1-olo
IT201600130538A1 (it) 2016-12-23 2018-06-23 Lundbeck Pharmaceuticals Italy S P A Processo per la produzione del delmopinolo
IT201600130729A1 (it) 2016-12-23 2018-06-23 Lundbeck Pharmaceuticals Italy S P A Processo per la produzione degli intermedi del delmopinolo
IT201700076821A1 (it) 2017-08-24 2019-02-24 Lundbeck Pharmaceuticals Italy S P A Nuovo sale del delmopinolo
US11780818B2 (en) 2020-01-31 2023-10-10 You First Services, Inc. Methods of making delmopinol and salts thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636382A (en) * 1980-03-21 1987-01-13 Ab Ferrosan Morpholino compounds and compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59164762A (ja) * 1983-03-09 1984-09-17 Univ Osaka 第２アミンからニトロンを合成する方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636382A (en) * 1980-03-21 1987-01-13 Ab Ferrosan Morpholino compounds and compositions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
C.Hootele’ et al., Bull. Soc. Chim. Belg., 1987, 96, 57. *

Also Published As

Publication number Publication date
FI910148A0 (fi) 1991-01-11
US5155220A (en) 1992-10-13
GR900100397A (en) 1991-10-10
NO911873D0 (no) 1991-05-14
NO179870B (no) 1996-09-23
ATE104968T1 (de) 1994-05-15
EP0426826B1 (en) 1994-04-27
IL94427A (en) 1994-07-31
AU631648B2 (en) 1992-12-03
EP0426826A1 (en) 1991-05-15
NO910131L (no) 1991-01-11
NO180120C (no) 1997-02-19
JP3042876B2 (ja) 2000-05-22
CA2187114C (en) 2002-03-19
HUT57215A (en) 1991-11-28
IE901748L (en) 1990-11-24
AU5675890A (en) 1990-12-18
NO910131D0 (no) 1991-01-11
GR1001407B (el) 1993-11-30
CA2032513C (en) 1996-12-17
CN1048218A (zh) 1991-01-02
CA2187114A1 (en) 1990-11-25
DK0426826T3 (da) 1994-07-04
IE65640B1 (en) 1995-11-15
GEP19971047B (en) 1997-11-26
IL94427A0 (en) 1991-03-10
JPH04500219A (ja) 1992-01-16
FI97057C (fi) 1996-10-10
HU905108D0 (en) 1991-07-29
PT94131B (pt) 1997-01-31
DE69008486T2 (de) 1994-09-15
NO179870C (no) 1997-01-02
ES2053195T3 (es) 1994-07-16
NO911873L (no) 1991-01-11
LV10276A (lv) 1994-10-20
DD300104A5 (de) 1992-05-21
CN1039325C (zh) 1998-07-29
CA2032513A1 (en) 1990-11-25
WO1990014342A1 (en) 1990-11-29
PT94131A (pt) 1991-01-08
KR0176248B1 (en) 1999-03-20
KR920701181A (ko) 1992-08-11
NZ233730A (en) 1992-09-25
HU205118B (en) 1992-03-30
FI97057B (fi) 1996-06-28
PH31619A (en) 1999-01-12
NO180120B (no) 1996-11-11
DE69008486D1 (de) 1994-06-01
LV10276B (en) 1995-08-20
RU2042670C1 (ru) 1995-08-27

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