MD423C2 - Procedeu de obţinere a delmopionului, compuşi intermediari pentru efectuarea procedeului - Google Patents

Procedeu de obţinere a delmopionului, compuşi intermediari pentru efectuarea procedeului

Info

Publication number
MD423C2
MD423C2 MD95-0039A MD950039A MD423C2 MD 423 C2 MD423 C2 MD 423C2 MD 950039 A MD950039 A MD 950039A MD 423 C2 MD423 C2 MD 423C2
Authority
MD
Moldova
Prior art keywords
delmopinol
realizing
preparation process
intermediate compositions
optional
Prior art date
Application number
MD95-0039A
Other languages
English (en)
Russian (ru)
Inventor
Sven Hernestam
Bernt Thelin
Elizabeth Seifert
Arne Nilsson
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8901837A external-priority patent/SE8901837D0/xx
Priority claimed from SE8901838A external-priority patent/SE8901838D0/xx
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Publication of MD423C2 publication Critical patent/MD423C2/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Luminescent Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Invenţia se referă la un procedeu nou de obţinere a delmopinolului, utilizând produsele intermediare, cu formuleleîn care R reprezintă 2-propilpentil, arbitrar cu una, două sau trei legături interne nesaturate, sau 2-propilpentil 2-substituit, arbitrar cu una sau două legături interne nesaturate, în care substituentul în poziţia 2 este grupa înlăturată.
MD95-0039A 1989-05-24 1994-07-14 Procedeu de obţinere a delmopionului, compuşi intermediari pentru efectuarea procedeului MD423C2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8901837A SE8901837D0 (sv) 1989-05-24 1989-05-24 Substituted isoxazolidines and isoxazolines
SE8901838A SE8901838D0 (sv) 1989-05-24 1989-05-24 New process and intermediates

Publications (1)

Publication Number Publication Date
MD423C2 true MD423C2 (ro) 1996-09-30

Family

ID=26660511

Family Applications (1)

Application Number Title Priority Date Filing Date
MD95-0039A MD423C2 (ro) 1989-05-24 1994-07-14 Procedeu de obţinere a delmopionului, compuşi intermediari pentru efectuarea procedeului

Country Status (26)

Country Link
US (1) US5155220A (ro)
EP (1) EP0426826B1 (ro)
JP (1) JP3042876B2 (ro)
KR (1) KR0176248B1 (ro)
CN (1) CN1039325C (ro)
AT (1) ATE104968T1 (ro)
AU (1) AU631648B2 (ro)
CA (2) CA2032513C (ro)
DD (1) DD300104A5 (ro)
DE (1) DE69008486T2 (ro)
DK (1) DK0426826T3 (ro)
ES (1) ES2053195T3 (ro)
FI (1) FI97057C (ro)
GE (1) GEP19971047B (ro)
GR (1) GR1001407B (ro)
HU (1) HU205118B (ro)
IE (1) IE65640B1 (ro)
IL (1) IL94427A (ro)
LV (1) LV10276B (ro)
MD (1) MD423C2 (ro)
NO (2) NO179870C (ro)
NZ (1) NZ233730A (ro)
PH (1) PH31619A (ro)
PT (1) PT94131B (ro)
RU (1) RU2042670C1 (ro)
WO (1) WO1990014342A1 (ro)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147632A (en) * 1990-10-31 1992-09-15 Warner-Lambert Company Anti-plaque compositions comprising a combination of morpholinoamino alcohol and chelating agent
GB9226857D0 (en) * 1992-12-23 1993-02-17 Boyd Edward A Pharmaceutical compositions
US5552757A (en) * 1994-05-27 1996-09-03 Littelfuse, Inc. Surface-mounted fuse device
US6878004B2 (en) * 2002-03-04 2005-04-12 Littelfuse, Inc. Multi-element fuse array
EP1631557B1 (en) 2003-06-12 2006-12-20 Btg International Limited Cyclic hydroxylamine as psychoactive compounds
US7233474B2 (en) * 2003-11-26 2007-06-19 Littelfuse, Inc. Vehicle electrical protection device and system employing same
GB0523435D0 (en) * 2005-11-17 2005-12-28 Sinclair Pharmaceuticals Ltd Process
DK3184150T3 (da) 2005-11-22 2019-09-02 Maelor Laboratories Ltd Behandling af infektioner i subgingivale lommer
GB0602424D0 (en) 2006-02-07 2006-03-22 Sinclair Pharmaceuticals Ltd Compounds
GB0604018D0 (en) 2006-02-28 2006-04-05 Sinclair Pharmaceuticals Ltd Method
GB0615814D0 (en) 2006-08-09 2006-09-20 Sinclair Pharmaceuticals Ltd Medicament
GB201105162D0 (en) 2011-03-28 2011-05-11 Lane Jonathan Improved deodorant formulations
IT201600130642A1 (it) 2016-12-23 2018-06-23 Lundbeck Pharmaceuticals Italy S P A Processo per la produzione di 2(3 alchilmorfolino)-etan-1-olo
IT201600130729A1 (it) 2016-12-23 2018-06-23 Lundbeck Pharmaceuticals Italy S P A Processo per la produzione degli intermedi del delmopinolo
IT201600130538A1 (it) 2016-12-23 2018-06-23 Lundbeck Pharmaceuticals Italy S P A Processo per la produzione del delmopinolo
IT201700076821A1 (it) 2017-08-24 2019-02-24 Lundbeck Pharmaceuticals Italy S P A Nuovo sale del delmopinolo
CN115315231B (zh) 2020-01-31 2024-03-22 优福斯特服务股份有限公司 制备地莫匹醇及其盐的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636382A (en) * 1980-03-21 1987-01-13 Ab Ferrosan Morpholino compounds and compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59164762A (ja) * 1983-03-09 1984-09-17 Univ Osaka 第２アミンからニトロンを合成する方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636382A (en) * 1980-03-21 1987-01-13 Ab Ferrosan Morpholino compounds and compositions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
C.Hootele’ et al., Bull. Soc. Chim. Belg., 1987, 96, 57. *

Also Published As

Publication number Publication date
DK0426826T3 (da) 1994-07-04
FI97057C (fi) 1996-10-10
HUT57215A (en) 1991-11-28
HU905108D0 (en) 1991-07-29
WO1990014342A1 (en) 1990-11-29
LV10276A (lv) 1994-10-20
EP0426826B1 (en) 1994-04-27
GEP19971047B (en) 1997-11-26
FI910148A0 (fi) 1991-01-11
IE901748L (en) 1990-11-24
RU2042670C1 (ru) 1995-08-27
PT94131B (pt) 1997-01-31
AU5675890A (en) 1990-12-18
IL94427A (en) 1994-07-31
CA2032513A1 (en) 1990-11-25
KR0176248B1 (en) 1999-03-20
DE69008486T2 (de) 1994-09-15
NO911873L (no) 1991-01-11
HU205118B (en) 1992-03-30
NO910131D0 (no) 1991-01-11
AU631648B2 (en) 1992-12-03
NO180120B (no) 1996-11-11
NO180120C (no) 1997-02-19
US5155220A (en) 1992-10-13
ES2053195T3 (es) 1994-07-16
DD300104A5 (de) 1992-05-21
CA2032513C (en) 1996-12-17
JPH04500219A (ja) 1992-01-16
KR920701181A (ko) 1992-08-11
DE69008486D1 (de) 1994-06-01
CA2187114C (en) 2002-03-19
IE65640B1 (en) 1995-11-15
EP0426826A1 (en) 1991-05-15
NO911873D0 (no) 1991-05-14
PH31619A (en) 1999-01-12
NO910131L (no) 1991-01-11
NZ233730A (en) 1992-09-25
IL94427A0 (en) 1991-03-10
GR900100397A (en) 1991-10-10
FI97057B (fi) 1996-06-28
GR1001407B (el) 1993-11-30
CN1048218A (zh) 1991-01-02
CA2187114A1 (en) 1990-11-25
PT94131A (pt) 1991-01-08
NO179870C (no) 1997-01-02
JP3042876B2 (ja) 2000-05-22
LV10276B (en) 1995-08-20
NO179870B (no) 1996-09-23
ATE104968T1 (de) 1994-05-15
CN1039325C (zh) 1998-07-29

Similar Documents

Publication Publication Date Title
MD423C2 (ro) Procedeu de obţinere a delmopionului, compuşi intermediari pentru efectuarea procedeului
UA32546C2 (uk) 1,2-заміщені 1н-імідазо[4,5-с]хінолін-4-аміни, проміжні сполуки для їх синтезу, антивірусна фармацевтична композиція, спосіб лікування інфікованих ссавців, спосіб індукування біосинтезу інтерферону у ссавців, спосіб уповільнення росту бластом
YU56995A (sh) Soli derivata indola
UA34428C2 (uk) Заміщені фенілімідазолідини, спосіб їх одержання, фармацевтична композиція, проміжні сполуки
NZ240230A (en) Mercaptoacetylamide derivatives; preparation, use and pharmaceutical compositions thereof
RU94042922A (ru) Новые соединения, способы их получения, фармацевтическая композиция
MY109143A (en) Sulfonamido-and sulfonamidocarbonylpyridine 2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals
ATE210147T1 (de) Glycokonjugate von modifizierten camptothecin- derivaten(a- oder b-ring-verknüpfung)
EE02962B1 (et) Mometasoonfuroaadi monohüdraat, selle valmistamismeetod ja farmatseutilised kompositsioonid
FR2376147A1 (fr) Prostaglandines bicycliques, utiles notamment comme anti-agglutinants des plaquettes sanguines et leur procede de preparation
IL58775A (en) Hydroxyethyl-azole compounds,their production and pharmaceutical compositions containing them
FR2361901A1 (fr) Derives de substitution de nucleotides et medicament contenant ces substances
MX17846A (es) Proceso para la preparacion de nuevos derivados de 9h purina.
GR900100326A (en) Saccharin derivatives useful as proteolytic enzyme inhibitors and preparation thereof
OA09016A (fr) Produits cathartiques.
GEP19971017B (en) Process of preparation of benzocycloalkenyldihydroxyalkanoic acids derivatives
ES2042488T3 (es) Productos intermedios para la produccion de podofilotoxina, y compuestos relacionados y procedimientos para su preparacion y utilizacion.
AU6319480A (en) 2-hydroxyalkyl-3,4,5-trihydroxypiperidines
MY120683A (en) New phenylamidine derivatives, processes for their preparation and their use as pharmaceuticals.
IL88971A (en) Disubstituted pyridines, process and intermediates, their preparation and pharmaceutical compositions containing them
MY120550A (en) Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols, processes for preparing them and their use as pharmaceutical compositions.
ES8301244A1 (es) Procedimiento para la obtencion de derivados de sisomicina.
ES8305783A1 (es) Procedimiento para la obtencion de derivados de aminociclitol saturados.
ES8304937A1 (es) Procedimiento para la obtencion de derivados de 2-amino-piridina sustituidos.
FR2401167A1 (fr) Derives de thienothiazine utiles comme medicaments