MD2550B2 - Preparat antibiotic cu eliberare lenta a ingredientului activ si utilizare a acestuia - Google Patents

Preparat antibiotic cu eliberare lenta a ingredientului activ si utilizare a acestuia Download PDF

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Publication number
MD2550B2
MD2550B2 MDA20020075A MD20020075A MD2550B2 MD 2550 B2 MD2550 B2 MD 2550B2 MD A20020075 A MDA20020075 A MD A20020075A MD 20020075 A MD20020075 A MD 20020075A MD 2550 B2 MD2550 B2 MD 2550B2
Authority
MD
Moldova
Prior art keywords
active ingredient
antibiotic
component
preparation
biologically active
Prior art date
Application number
MDA20020075A
Other languages
English (en)
Other versions
MD2550C2 (ro
MD20020075A (ro
Inventor
Sebastian Vogt
Matthias Schnabelrauch
Klaus-Dieter Kuhn
Original Assignee
Heraeus Kulzer Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heraeus Kulzer Gmbh & Co Kg filed Critical Heraeus Kulzer Gmbh & Co Kg
Publication of MD20020075A publication Critical patent/MD20020075A/ro
Publication of MD2550B2 publication Critical patent/MD2550B2/ro
Publication of MD2550C2 publication Critical patent/MD2550C2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
MDA20020075A 2001-03-22 2002-02-13 Preparat antibiotic cu eliberare lenta a ingredientului activ şi utilizare a acestuia MD2550C2 (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10114244A DE10114244A1 (de) 2001-03-22 2001-03-22 Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung

Publications (3)

Publication Number Publication Date
MD20020075A MD20020075A (ro) 2002-11-30
MD2550B2 true MD2550B2 (ro) 2004-09-30
MD2550C2 MD2550C2 (ro) 2005-04-30

Family

ID=7678691

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20020075A MD2550C2 (ro) 2001-03-22 2002-02-13 Preparat antibiotic cu eliberare lenta a ingredientului activ şi utilizare a acestuia

Country Status (32)

Country Link
US (1) US6913764B2 (ro)
EP (1) EP1243257B1 (ro)
JP (1) JP4181331B2 (ro)
CN (1) CN100486589C (ro)
AT (1) ATE258431T1 (ro)
AU (1) AU768962B2 (ro)
BG (1) BG65467B1 (ro)
BR (1) BR0200876A (ro)
CA (1) CA2378490C (ro)
CZ (1) CZ302690B6 (ro)
DE (2) DE10114244A1 (ro)
DK (1) DK1243257T3 (ro)
EE (1) EE200200153A (ro)
ES (1) ES2213717T3 (ro)
GE (1) GEP20053447B (ro)
HR (1) HRP20020240B1 (ro)
HU (1) HUP0201045A2 (ro)
IL (1) IL148703A (ro)
IS (2) IS2501B (ro)
MD (1) MD2550C2 (ro)
MX (1) MXPA02003007A (ro)
NO (1) NO331876B1 (ro)
NZ (1) NZ517922A (ro)
PL (1) PL204986B1 (ro)
PT (1) PT1243257E (ro)
RU (1) RU2264230C2 (ro)
SA (1) SA02230037B1 (ro)
SK (1) SK286493B6 (ro)
TR (1) TR200400244T4 (ro)
UA (1) UA71030C2 (ro)
YU (1) YU11802A (ro)
ZA (1) ZA200202254B (ro)

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* Cited by examiner, † Cited by third party
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DE10114244A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung
DE10114245A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung
DE10318991A1 (de) * 2003-04-25 2004-11-18 Heraeus Kulzer Gmbh & Co. Kg Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung
WO2005056608A1 (en) * 2003-12-04 2005-06-23 University Of Utah Research Foundation Modified macromolecules and methods of making and using thereof
PT1781264E (pt) 2004-08-04 2013-10-16 Evonik Corp Métodos para o fabrico de dispositivis de administração e dispositivos para a mesma
DE102004060666B3 (de) 2004-12-15 2006-03-30 Heraeus Kulzer Gmbh Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung
DE102005002703C5 (de) 2005-01-19 2013-07-04 Heraeus Kulzer Gmbh Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung
ES2507552T3 (es) * 2005-10-27 2014-10-15 Nexilis Ag Implante que contiene amino-bisfosfonatos y procedimiento para su producción
KR101315925B1 (ko) * 2005-10-27 2013-10-08 토멘 메디칼 아게 치과용 임플란트 및 그의 제조 방법
WO2007056667A2 (en) * 2005-11-04 2007-05-18 Rush University Medical Center Plastic implant impregnated with an antibiotic
DE102006007245A1 (de) 2006-02-15 2007-08-23 Heraeus Kulzer Gmbh Implantatmaterial
RU2335510C2 (ru) * 2006-02-22 2008-10-10 Институт высокомолекулярных соединений РАН Водорастворимые полимерные комплексы антибиотиков-аминогликозидов
DE102006037362B3 (de) * 2006-08-09 2007-09-20 Heraeus Kulzer Gmbh Knochenersatzmaterial
US7923021B2 (en) * 2007-07-24 2011-04-12 University Of Memphis Research Foundation Local delivery method and composition
DE102007039871A1 (de) 2007-08-21 2009-02-26 Friedrich-Baur-Gmbh Weichgewebe-Implantat mit antibakterieller Wirkung
ES2718612T3 (es) 2007-12-20 2019-07-03 Evonik Corp Procedimiento para preparar micropartículas que tienen un bajo volumen de disolvente residual
CN101758337B (zh) * 2009-12-03 2012-02-15 湖南阿斯达生化科技有限公司 一种助焊剂用非卤素活性剂
WO2013010045A1 (en) 2011-07-12 2013-01-17 Biotime Inc. Novel methods and formulations for orthopedic cell therapy
US20210361696A1 (en) * 2017-06-16 2021-11-25 Boris Farber Biologically active combinatorial polysaccharide derivatives
EP3648740A1 (en) 2017-07-07 2020-05-13 EpicentRx, Inc. Compositions for parenteral administration of therapeutic agents
IL256312A (en) 2017-12-14 2018-01-31 Omrix Biopharmaceuticals Ltd Antibacterial preparations containing minocycline and oxidized cellulose

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Also Published As

Publication number Publication date
BR0200876A (pt) 2003-03-11
CN1376469A (zh) 2002-10-30
CA2378490A1 (en) 2002-09-22
TR200400244T4 (tr) 2004-04-21
RU2264230C2 (ru) 2005-11-20
US6913764B2 (en) 2005-07-05
NO20021390L (no) 2002-09-23
YU11802A (sh) 2004-12-31
ZA200202254B (en) 2002-10-10
HUP0201045A2 (hu) 2003-02-28
BG65467B1 (bg) 2008-09-30
NO20021390D0 (no) 2002-03-20
SK286493B6 (sk) 2008-11-06
NZ517922A (en) 2003-08-29
JP4181331B2 (ja) 2008-11-12
EP1243257B1 (de) 2004-01-28
SK3892002A3 (en) 2002-10-08
EE200200153A (et) 2002-12-16
HU0201045D0 (ro) 2002-05-29
PT1243257E (pt) 2004-06-30
IL148703A0 (en) 2002-11-10
PL352920A1 (en) 2002-09-23
JP2002322097A (ja) 2002-11-08
CZ302690B6 (cs) 2011-09-07
GEP20053447B (en) 2005-02-25
CA2378490C (en) 2008-05-13
MD2550C2 (ro) 2005-04-30
AU2755402A (en) 2002-09-26
HRP20020240B1 (en) 2005-04-30
PL204986B1 (pl) 2010-02-26
CZ2002871A3 (cs) 2002-11-13
IS6270A (is) 2002-09-22
DE50200223D1 (de) 2004-03-04
IS6269A (is) 2002-09-22
DE10114244A1 (de) 2002-10-02
ES2213717T3 (es) 2004-09-01
NO331876B1 (no) 2012-04-23
EP1243257A1 (de) 2002-09-25
DK1243257T3 (da) 2004-05-10
MXPA02003007A (es) 2003-08-20
AU768962B2 (en) 2004-01-08
CN100486589C (zh) 2009-05-13
ATE258431T1 (de) 2004-02-15
BG106454A (en) 2002-10-31
SA02230037B1 (ar) 2007-04-15
US20020182251A1 (en) 2002-12-05
UA71030C2 (uk) 2004-11-15
HRP20020240A2 (en) 2002-12-31
IS2501B (is) 2009-03-15
IL148703A (en) 2006-07-05
MD20020075A (ro) 2002-11-30

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Legal Events

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KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees