MD2550B2 - Preparat antibiotic cu eliberare lenta a ingredientului activ si utilizare a acestuia - Google Patents

Preparat antibiotic cu eliberare lenta a ingredientului activ si utilizare a acestuia

Info

Publication number
MD2550B2
MD2550B2 MDA20020075A MD20020075A MD2550B2 MD 2550 B2 MD2550 B2 MD 2550B2 MD A20020075 A MDA20020075 A MD A20020075A MD 20020075 A MD20020075 A MD 20020075A MD 2550 B2 MD2550 B2 MD 2550B2
Authority
MD
Moldova
Prior art keywords
active ingredient
antibiotic
component
preparation
biologically active
Prior art date
Application number
MDA20020075A
Other languages
English (en)
Other versions
MD20020075A (ro
MD2550C2 (ro
Inventor
Sebastian Vogt
Matthias Schnabelrauch
Klaus-Dieter Kuhn
Original Assignee
Heraeus Kulzer Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heraeus Kulzer Gmbh & Co Kg filed Critical Heraeus Kulzer Gmbh & Co Kg
Publication of MD20020075A publication Critical patent/MD20020075A/ro
Publication of MD2550B2 publication Critical patent/MD2550B2/ro
Publication of MD2550C2 publication Critical patent/MD2550C2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
MDA20020075A 2001-03-22 2002-02-13 Preparat antibiotic cu eliberare lenta a ingredientului activ şi utilizare a acestuia MD2550C2 (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10114244A DE10114244A1 (de) 2001-03-22 2001-03-22 Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung

Publications (3)

Publication Number Publication Date
MD20020075A MD20020075A (ro) 2002-11-30
MD2550B2 true MD2550B2 (ro) 2004-09-30
MD2550C2 MD2550C2 (ro) 2005-04-30

Family

ID=7678691

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20020075A MD2550C2 (ro) 2001-03-22 2002-02-13 Preparat antibiotic cu eliberare lenta a ingredientului activ şi utilizare a acestuia

Country Status (32)

Country Link
US (1) US6913764B2 (ro)
EP (1) EP1243257B1 (ro)
JP (1) JP4181331B2 (ro)
CN (1) CN100486589C (ro)
AT (1) ATE258431T1 (ro)
AU (1) AU768962B2 (ro)
BG (1) BG65467B1 (ro)
BR (1) BR0200876A (ro)
CA (1) CA2378490C (ro)
CZ (1) CZ302690B6 (ro)
DE (2) DE10114244A1 (ro)
DK (1) DK1243257T3 (ro)
EE (1) EE200200153A (ro)
ES (1) ES2213717T3 (ro)
GE (1) GEP20053447B (ro)
HR (1) HRP20020240B1 (ro)
HU (1) HUP0201045A2 (ro)
IL (1) IL148703A (ro)
IS (2) IS6270A (ro)
MD (1) MD2550C2 (ro)
MX (1) MXPA02003007A (ro)
NO (1) NO331876B1 (ro)
NZ (1) NZ517922A (ro)
PL (1) PL204986B1 (ro)
PT (1) PT1243257E (ro)
RU (1) RU2264230C2 (ro)
SA (1) SA02230037B1 (ro)
SK (1) SK286493B6 (ro)
TR (1) TR200400244T4 (ro)
UA (1) UA71030C2 (ro)
YU (1) YU11802A (ro)
ZA (1) ZA200202254B (ro)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10114245A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung
DE10114244A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung
DE10318991A1 (de) * 2003-04-25 2004-11-18 Heraeus Kulzer Gmbh & Co. Kg Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung
ZA200604869B (en) * 2003-12-04 2007-11-28 Univ Utah Res Found Modified macromolecules and methods of making and using thereof
EP1781264B1 (en) 2004-08-04 2013-07-24 Evonik Corporation Methods for manufacturing delivery devices and devices thereof
DE102004060666B3 (de) 2004-12-15 2006-03-30 Heraeus Kulzer Gmbh Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung
DE102005002703C5 (de) * 2005-01-19 2013-07-04 Heraeus Kulzer Gmbh Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung
US9050391B2 (en) * 2005-10-27 2015-06-09 Nexilis Ag Implant and production method for said implant
US8940320B2 (en) * 2005-10-27 2015-01-27 Thommen Medical Ag Dental implant and production method for said implant
US20070213835A1 (en) * 2005-11-04 2007-09-13 Markus Wimmer Plastic implant impregnated with an antibiotic
DE102006007245A1 (de) 2006-02-15 2007-08-23 Heraeus Kulzer Gmbh Implantatmaterial
DE102006037362B3 (de) * 2006-08-09 2007-09-20 Heraeus Kulzer Gmbh Knochenersatzmaterial
US7923021B2 (en) * 2007-07-24 2011-04-12 University Of Memphis Research Foundation Local delivery method and composition
DE102007039871A1 (de) 2007-08-21 2009-02-26 Friedrich-Baur-Gmbh Weichgewebe-Implantat mit antibakterieller Wirkung
EP2222281B1 (en) 2007-12-20 2018-12-05 Evonik Corporation Process for preparing microparticles having a low residual solvent volume
CN101758337B (zh) * 2009-12-03 2012-02-15 湖南阿斯达生化科技有限公司 一种助焊剂用非卤素活性剂
WO2013010045A1 (en) 2011-07-12 2013-01-17 Biotime Inc. Novel methods and formulations for orthopedic cell therapy
WO2018231089A1 (ru) * 2017-06-16 2018-12-20 Борис Славинович ФАРБЕР Биологически активные комбинаторные производные полисахаридов
IL271777B2 (en) 2017-07-07 2024-09-01 Epicentrx Inc Preparations for intravenous administration of medical substances
IL256312A (en) * 2017-12-14 2018-01-31 Omrix Biopharmaceuticals Ltd Antibacterial preparations containing minocycline and oxidized cellulose

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US356759A (en) * 1887-02-01 Paul gmehlikt
US3091572A (en) 1962-07-16 1963-05-28 Schering Corp Gentamycin and method of production
GB1120992A (en) * 1965-04-24 1968-07-24 Fisons Pharmaceuticals Ltd Aerosol compositions
ES315101A1 (es) 1965-07-08 1966-01-01 Folch Vazquez Conrado Procedimiento de preparaciën de nuevos derivados de tetraciclina
FR6476M (ro) 1967-06-06 1968-11-18
DE2320373B2 (de) * 1973-04-21 1978-04-06 Merck Patent Gmbh, 6100 Darmstadt Antibioticahaltiges Mittel und seine Verwendung als chirurgisches Kunststoffmaterial
FR2272680B1 (ro) * 1974-05-29 1978-07-21 Hosbon Sa Lab
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AR216922A1 (es) * 1976-11-11 1980-02-15 Merck Patent Gmbh Procedimiento para la fabricacion de un medio quirurgico
JPS5391113A (en) * 1977-01-21 1978-08-10 Meiji Seika Kaisha Ltd Preparation of suppository of antibiotics
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
EP0052916B1 (en) * 1980-11-10 1985-01-02 Alza Corporation Erodible polymer containing erosion rate modifier
DE3206725A1 (de) * 1981-05-13 1982-12-02 Merck Patent Gmbh, 6100 Darmstadt Schwer loesliche salze von aminoglykosidantibiotika
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US5035891A (en) * 1987-10-05 1991-07-30 Syntex (U.S.A.) Inc. Controlled release subcutaneous implant
FR2668367B1 (fr) * 1990-10-26 1994-05-13 Centre Nal Recherc Scientifique Medicament implantable a effet prolonge.
US5709875A (en) 1990-10-26 1998-01-20 Centre National De La Rechierche Scientifique (C.N.R.S) Implantable biodegradable material and process for its production
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FR2697539B1 (fr) * 1992-11-03 1994-12-02 Pechiney Recherche Méthode, dispositif et appareil de traitement de surface de corps de boîtes métalliques, en particulier an al ou ses alliages.
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WO1995027517A1 (fr) * 1994-04-06 1995-10-19 Lyzion Australia Pty. Ltd. Preparation pharmaceutique pour application locale, et procede de fabrication
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US5674142A (en) * 1996-04-16 1997-10-07 Sram Corporation Control cable adjustment device
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DE10114244A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung

Also Published As

Publication number Publication date
RU2264230C2 (ru) 2005-11-20
AU768962B2 (en) 2004-01-08
UA71030C2 (uk) 2004-11-15
IL148703A (en) 2006-07-05
CA2378490C (en) 2008-05-13
DE50200223D1 (de) 2004-03-04
YU11802A (sh) 2004-12-31
CN1376469A (zh) 2002-10-30
HRP20020240B1 (en) 2005-04-30
BG106454A (en) 2002-10-31
SK286493B6 (sk) 2008-11-06
HU0201045D0 (ro) 2002-05-29
EP1243257A1 (de) 2002-09-25
AU2755402A (en) 2002-09-26
HUP0201045A2 (hu) 2003-02-28
JP2002322097A (ja) 2002-11-08
MD20020075A (ro) 2002-11-30
ZA200202254B (en) 2002-10-10
ATE258431T1 (de) 2004-02-15
IL148703A0 (en) 2002-11-10
DE10114244A1 (de) 2002-10-02
CA2378490A1 (en) 2002-09-22
CN100486589C (zh) 2009-05-13
HRP20020240A2 (en) 2002-12-31
TR200400244T4 (tr) 2004-04-21
IS6269A (is) 2002-09-22
MD2550C2 (ro) 2005-04-30
NO331876B1 (no) 2012-04-23
NO20021390L (no) 2002-09-23
EP1243257B1 (de) 2004-01-28
MXPA02003007A (es) 2003-08-20
CZ302690B6 (cs) 2011-09-07
US6913764B2 (en) 2005-07-05
IS6270A (is) 2002-09-22
GEP20053447B (en) 2005-02-25
PL352920A1 (en) 2002-09-23
SK3892002A3 (en) 2002-10-08
PT1243257E (pt) 2004-06-30
BG65467B1 (bg) 2008-09-30
DK1243257T3 (da) 2004-05-10
ES2213717T3 (es) 2004-09-01
EE200200153A (et) 2002-12-16
SA02230037B1 (ar) 2007-04-15
US20020182251A1 (en) 2002-12-05
JP4181331B2 (ja) 2008-11-12
IS2501B (is) 2009-03-15
CZ2002871A3 (cs) 2002-11-13
PL204986B1 (pl) 2010-02-26
NO20021390D0 (no) 2002-03-20
BR0200876A (pt) 2003-03-11
NZ517922A (en) 2003-08-29

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Legal Events

Date Code Title Description
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees