BRPI0618374A2 - uso de um composto ou um derivado do mesmo farmaceuticamente aceitável, métodos para matar microorganismos clinicamente latentes em um mamìfero, para tratar ou prevenir uma infecção microbiana em um mamìfero, para esterilizar um objeto, para preservar um material inorgánico ou orgánico, para tratar uma doença, para reduzir a dose de agente antimicrobiano convencional requerida para tratar uma infecção microbiana e para tratar uma doença de protozoário em um mamìfero, produto combinado, formulação, uso de um produto combinado, composto, e, processo para a preparação do mesmo - Google Patents
uso de um composto ou um derivado do mesmo farmaceuticamente aceitável, métodos para matar microorganismos clinicamente latentes em um mamìfero, para tratar ou prevenir uma infecção microbiana em um mamìfero, para esterilizar um objeto, para preservar um material inorgánico ou orgánico, para tratar uma doença, para reduzir a dose de agente antimicrobiano convencional requerida para tratar uma infecção microbiana e para tratar uma doença de protozoário em um mamìfero, produto combinado, formulação, uso de um produto combinado, composto, e, processo para a preparação do mesmo Download PDFInfo
- Publication number
- BRPI0618374A2 BRPI0618374A2 BRPI0618374-3A BRPI0618374A BRPI0618374A2 BR PI0618374 A2 BRPI0618374 A2 BR PI0618374A2 BR PI0618374 A BRPI0618374 A BR PI0618374A BR PI0618374 A2 BRPI0618374 A2 BR PI0618374A2
- Authority
- BR
- Brazil
- Prior art keywords
- mammal
- treat
- treating
- compound
- combined product
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 8
- 208000015181 infectious disease Diseases 0.000 title abstract 5
- 241000124008 Mammalia Species 0.000 title abstract 4
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 230000000813 microbial effect Effects 0.000 title abstract 3
- 244000005700 microbiome Species 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000001954 sterilising effect Effects 0.000 title abstract 2
- 239000004599 antimicrobial Substances 0.000 title 1
- 239000011147 inorganic material Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000011368 organic material Substances 0.000 title 1
- 230000003515 anti-microbian Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract 1
Classifications
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- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- C—CHEMISTRY; METALLURGY
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- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
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Abstract
USO DE UM COMPOSTO OU UM DERIVADO DO MESMO FARMACEUTICAMENTE ACEITáVEL, MéTODOS PARA MATAR MICROORGANISMOS CLINICAMENTE LATENTES EM UM MAMìFERO, PARA TRATAR OU PREVENIR UMA INFECçãO MICROBIANA EM UM MAMìFERO, PARA ESTERILIZAR UM OBJETO, PARA PRESERVAR UM MATERIAL INORGáNICO OU ORGáNICO, PARA TRATAR UMA DOENçA, PARA REDUZIR A DOSE DE AGENTE ANTIMICROBIANO CONVENCIONAL REQUERIDA PARA TRATAR UMA INFECçãO MICROBIANA E PARA TRATAR UMA DOENçA DE PROTOZOáRIO EM UM MAMìFERO, PRODUTO COMBINADO, FORMULAçãO, USO DE UM PRODUTO COMBINADO, COMPOSTO, E, PROCESSO PARA A PREPARAçãO DO MESMO. é fornecido o uso de compostos da fórmula (I), em que R^2^ R^3^ e X têm os significados dados na descrição, para a preparação de um medicamento para matar microorganismos clinicamente latentes. Também é fornecido o uso de compostos da fórmula (I) para tratar infecções microbianas, assim como certos compostos da fórmula (I) por si.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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GBGB0522715.2A GB0522715D0 (en) | 2005-11-08 | 2005-11-08 | New use |
PCT/GB2006/004178 WO2007054693A1 (en) | 2005-11-08 | 2006-11-08 | Use of pyrroloquinoline compounds to kill clinically latent microorganisms |
Publications (1)
Publication Number | Publication Date |
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BRPI0618374A2 true BRPI0618374A2 (pt) | 2011-08-30 |
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BRPI0618374-3A BRPI0618374A2 (pt) | 2005-11-08 | 2006-11-08 | uso de um composto ou um derivado do mesmo farmaceuticamente aceitável, métodos para matar microorganismos clinicamente latentes em um mamìfero, para tratar ou prevenir uma infecção microbiana em um mamìfero, para esterilizar um objeto, para preservar um material inorgánico ou orgánico, para tratar uma doença, para reduzir a dose de agente antimicrobiano convencional requerida para tratar uma infecção microbiana e para tratar uma doença de protozoário em um mamìfero, produto combinado, formulação, uso de um produto combinado, composto, e, processo para a preparação do mesmo |
Country Status (22)
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US (3) | US8207187B2 (pt) |
EP (1) | EP1945211B1 (pt) |
JP (1) | JP5542336B2 (pt) |
KR (1) | KR101148049B1 (pt) |
CN (1) | CN101351203B (pt) |
AU (1) | AU2006313590C1 (pt) |
BR (1) | BRPI0618374A2 (pt) |
CA (1) | CA2628729C (pt) |
DK (1) | DK1945211T3 (pt) |
ES (1) | ES2558685T3 (pt) |
GB (1) | GB0522715D0 (pt) |
HK (1) | HK1127551A1 (pt) |
HR (1) | HRP20160043T1 (pt) |
HU (1) | HUE026568T2 (pt) |
IL (1) | IL191260A (pt) |
NZ (1) | NZ568035A (pt) |
PL (1) | PL1945211T3 (pt) |
PT (1) | PT1945211E (pt) |
RU (1) | RU2404982C2 (pt) |
SI (1) | SI1945211T1 (pt) |
WO (1) | WO2007054693A1 (pt) |
ZA (1) | ZA200804454B (pt) |
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RU2457208C2 (ru) * | 2009-07-06 | 2012-07-27 | Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО "ПГФА Росздрава") | 1H-ПИРРОЛО[3,4-b]ХИНОЛИН-3,9(2H,4H)-ДИОНЫ, ОБЛАДАЮЩИЕ ПРОТИВОТУБЕРКУЛЕЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ |
BR112012024999A2 (pt) | 2010-03-30 | 2016-07-12 | Helperby Therapeutics Ltd | combinação e uso |
GB201013207D0 (en) | 2010-08-05 | 2010-09-22 | Helperby Therapeutics Ltd | Novel combination |
ES2826884T3 (es) | 2010-08-05 | 2021-05-19 | Helperby Therapeutics Ltd | Combinación de un compuesto de pirroloquinolina y un agente antimicrobiano betalactámico, mupirocina o clorhexidina |
GB201015079D0 (en) | 2010-09-10 | 2010-10-27 | Helperby Therapeutics Ltd | Novel use |
EP2624817A1 (en) * | 2010-10-08 | 2013-08-14 | Helperby Therapeutics Limited | Novel composition |
KR101254038B1 (ko) * | 2011-01-12 | 2013-04-12 | 한국화학연구원 | 퀴놀린올 화합물을 유효성분으로 포함하는 항진균 조성물 |
GB201107755D0 (en) | 2011-05-10 | 2011-06-22 | Helperby Therapeutics Ltd | Novel compounds |
EP2830632A4 (en) | 2012-03-27 | 2015-10-21 | Cempra Pharmaceuticals Inc | PARENTERAL FORMULATIONS FOR THE ADMINISTRATION OF MACROLIDE ANTIBIOTICS |
AU2014239959A1 (en) | 2013-03-14 | 2015-10-01 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
US9751908B2 (en) | 2013-03-15 | 2017-09-05 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
LT3027613T (lt) * | 2013-07-25 | 2018-07-25 | Uniwersytet Jagiellonski | Pirolochinolino dariniai kaip 5-ht6 antagonistai, jų gavimas ir panaudojimas |
WO2015192031A1 (en) * | 2014-06-12 | 2015-12-17 | Cem-102 Pharmaceuticals, Inc. | Compositions and methods for treating bone and joint infections |
GB201416351D0 (en) * | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Heterocyclic derivatives |
EP3283178A1 (en) | 2015-04-11 | 2018-02-21 | Helperby Therapeutics Limited | Oral composition |
US10653679B2 (en) * | 2015-05-04 | 2020-05-19 | Board Of Trustees Of Michigan State University | Compositions and methods for inhibiting bacterial growth |
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CN108660189B (zh) * | 2018-05-30 | 2021-09-07 | 杭州千基生物科技有限公司 | 一种用于尿路感染病原体的量子点核酸检测的试剂盒 |
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2005
- 2005-11-08 GB GBGB0522715.2A patent/GB0522715D0/en not_active Ceased
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2006
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- 2006-11-08 PT PT68084722T patent/PT1945211E/pt unknown
- 2006-11-08 WO PCT/GB2006/004178 patent/WO2007054693A1/en active Application Filing
- 2006-11-08 BR BRPI0618374-3A patent/BRPI0618374A2/pt active Search and Examination
- 2006-11-08 RU RU2008122912/04A patent/RU2404982C2/ru not_active IP Right Cessation
- 2006-11-08 HU HUE06808472A patent/HUE026568T2/hu unknown
- 2006-11-08 CA CA2628729A patent/CA2628729C/en active Active
- 2006-11-08 PL PL06808472T patent/PL1945211T3/pl unknown
- 2006-11-08 JP JP2008539493A patent/JP5542336B2/ja active Active
- 2006-11-08 US US12/092,947 patent/US8207187B2/en active Active
- 2006-11-08 CN CN2006800500487A patent/CN101351203B/zh active Active
- 2006-11-08 DK DK06808472.2T patent/DK1945211T3/en active
- 2006-11-08 SI SI200632016T patent/SI1945211T1/sl unknown
- 2006-11-08 AU AU2006313590A patent/AU2006313590C1/en not_active Ceased
- 2006-11-08 ES ES06808472.2T patent/ES2558685T3/es active Active
- 2006-11-08 KR KR1020087013544A patent/KR101148049B1/ko active IP Right Grant
- 2006-11-08 EP EP06808472.2A patent/EP1945211B1/en active Active
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- 2012-05-17 US US13/473,707 patent/US9694006B2/en active Active
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