MC2226A1 - Oxetannones - Google Patents

Oxetannones

Info

Publication number
MC2226A1
MC2226A1 MC912172A MC2172A MC2226A1 MC 2226 A1 MC2226 A1 MC 2226A1 MC 912172 A MC912172 A MC 912172A MC 2172 A MC2172 A MC 2172A MC 2226 A1 MC2226 A1 MC 2226A1
Authority
MC
Monaco
Prior art keywords
oxetannones
oxetanones
novel
formula
image
Prior art date
Application number
MC912172A
Other languages
English (en)
French (fr)
Inventor
Derungs Romano
Peter Maerki Hans
Stalder Henri
Szente Andre
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC2226A1 publication Critical patent/MC2226A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C07D305/12—Beta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
MC912172A 1990-02-26 1991-02-21 Oxetannones MC2226A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH60490 1990-02-26
CH400590 1990-12-17

Publications (1)

Publication Number Publication Date
MC2226A1 true MC2226A1 (fr) 1993-02-02

Family

ID=25685091

Family Applications (1)

Application Number Title Priority Date Filing Date
MC912172A MC2226A1 (fr) 1990-02-26 1991-02-21 Oxetannones

Country Status (18)

Country Link
EP (1) EP0444482B1 (fi)
JP (1) JP2753403B2 (fi)
KR (1) KR0183036B1 (fi)
AT (1) ATE133167T1 (fi)
AU (1) AU645291B2 (fi)
CA (1) CA2035967C (fi)
DE (1) DE59107262D1 (fi)
DK (1) DK0444482T3 (fi)
ES (1) ES2082869T3 (fi)
FI (1) FI115054B (fi)
GR (1) GR3019618T3 (fi)
HU (1) HU218272B (fi)
IE (1) IE72196B1 (fi)
IL (1) IL97148A (fi)
MC (1) MC2226A1 (fi)
NO (1) NO177055C (fi)
NZ (1) NZ237170A (fi)
PT (1) PT96887B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2035972C (en) * 1990-02-23 2006-07-11 Martin Karpf Process for the preparation of oxetanones
CA2098167C (en) * 1992-06-24 2006-12-19 Dorothea Isler Foodstuffs and feedstuffs containing a lipase inhibitor
NL1004559C2 (nl) * 1996-11-18 1998-05-19 Unilife Boter.
US6342519B2 (en) * 1999-10-29 2002-01-29 2 Pro Chemical Oxetanone derivatives
MXPA01006755A (es) * 1999-10-29 2003-05-15 Jason Gentry Mullins John Derivados de la oxetanona.
US6348492B1 (en) * 1999-10-29 2002-02-19 2Pro Chemical Oxetanone derivatives
US7074822B2 (en) 2004-02-23 2006-07-11 Solvay Pharmaceuticals Gmbh Alkyl carbamate-substituted β-lactones, process for their preparation, and pharmaceutical compositions containing them
DE102004009076A1 (de) * 2004-02-23 2005-10-27 Solvay Pharmaceuticals Gmbh Alkylcarbamat-substituierte β-Lactone, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
WO2009059046A1 (en) * 2007-10-31 2009-05-07 Burnham Institute For Medical Research Beta-lactone compounds
CN111343999B (zh) * 2017-07-12 2022-03-01 梅约医学教育与研究基金会 减少脂毒性损伤的化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS608117B2 (ja) * 1977-02-08 1985-02-28 財団法人微生物化学研究会 新生理活性物質エステラスチンおよびその製造法
GB2023604B (en) * 1978-05-25 1982-07-28 Microbial Chem Res Found Physiologically active derivatives of esterastin and production thereof
JPH0669130B2 (ja) * 1984-08-09 1994-08-31 三菱電機株式会社 遅延線

Also Published As

Publication number Publication date
KR910021391A (ko) 1991-12-20
AU7122891A (en) 1991-08-29
FI910925A (fi) 1991-08-27
IL97148A (en) 1996-11-14
NZ237170A (en) 1993-12-23
PT96887A (pt) 1991-10-31
NO177055B (no) 1995-04-03
AU645291B2 (en) 1994-01-13
ATE133167T1 (de) 1996-02-15
NO910729L (no) 1991-08-27
IE72196B1 (en) 1997-03-26
KR0183036B1 (ko) 1999-05-01
DE59107262D1 (de) 1996-02-29
PT96887B (pt) 1998-09-30
NO910729D0 (no) 1991-02-25
HUT56557A (en) 1991-09-30
JP2753403B2 (ja) 1998-05-20
IL97148A0 (en) 1992-05-25
IE910631A1 (en) 1991-08-28
EP0444482A2 (de) 1991-09-04
EP0444482B1 (de) 1996-01-17
DK0444482T3 (da) 1996-05-06
ES2082869T3 (es) 1996-04-01
HU218272B (en) 2000-07-28
JPH0770099A (ja) 1995-03-14
CA2035967C (en) 2001-10-16
EP0444482A3 (en) 1991-12-04
FI910925A0 (fi) 1991-02-26
NO177055C (no) 1995-07-12
GR3019618T3 (en) 1996-07-31
CA2035967A1 (en) 1991-08-27
FI115054B (fi) 2005-02-28

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