MC1693A1 - Nouveaux composes,compositions les contenant et intermediaires pour leur preparation - Google Patents

Nouveaux composes,compositions les contenant et intermediaires pour leur preparation

Info

Publication number
MC1693A1
MC1693A1 MC851788A MC1788A MC1693A1 MC 1693 A1 MC1693 A1 MC 1693A1 MC 851788 A MC851788 A MC 851788A MC 1788 A MC1788 A MC 1788A MC 1693 A1 MC1693 A1 MC 1693A1
Authority
MC
Monaco
Prior art keywords
preparation
intermediates
compositions containing
novel compounds
compounds
Prior art date
Application number
MC851788A
Other languages
English (en)
French (fr)
Inventor
Karl-Witold Franzmann
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MC1693A1 publication Critical patent/MC1693A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Dental Preparations (AREA)
  • Hydrogenated Pyridines (AREA)
  • Quinoline Compounds (AREA)
MC851788A 1984-08-01 1985-07-31 Nouveaux composes,compositions les contenant et intermediaires pour leur preparation MC1693A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848419658A GB8419658D0 (en) 1984-08-01 1984-08-01 Nitrogen containing heterocyclic compounds

Publications (1)

Publication Number Publication Date
MC1693A1 true MC1693A1 (fr) 1986-07-18

Family

ID=10564801

Family Applications (1)

Application Number Title Priority Date Filing Date
MC851788A MC1693A1 (fr) 1984-08-01 1985-07-31 Nouveaux composes,compositions les contenant et intermediaires pour leur preparation

Country Status (25)

Country Link
US (2) US4968698A (da)
EP (1) EP0170524B1 (da)
JP (2) JPH0688903B2 (da)
KR (1) KR920004484B1 (da)
CN (1) CN85106609A (da)
AT (1) ATE78163T1 (da)
AU (1) AU597564B2 (da)
CA (1) CA1291993C (da)
CS (1) CS266332B2 (da)
DD (1) DD236525A5 (da)
DE (1) DE3586340T2 (da)
DK (1) DK347685A (da)
ES (3) ES8701730A1 (da)
FI (1) FI86848C (da)
GB (1) GB8419658D0 (da)
GR (1) GR851879B (da)
HU (1) HU194834B (da)
IE (1) IE58661B1 (da)
IL (1) IL75978A (da)
MC (1) MC1693A1 (da)
NZ (1) NZ212929A (da)
PH (1) PH27347A (da)
PL (1) PL147636B1 (da)
PT (1) PT80893B (da)
ZA (1) ZA855800B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8717374D0 (en) * 1987-07-22 1987-08-26 Smith Kline French Lab Pharmaceutically active compounds
KR960704886A (ko) * 1993-09-10 1996-10-09 베르너 발데크 포토크롬 화합물, 그의 제조 방법과 제조 중간체 및 그의 용도 (Photochromic Compounds, Methods and Intermediates for Producing Them and Their Use)
WO2001009101A1 (en) * 1999-07-29 2001-02-08 EGIS Gyógyszergyár Rt. Isoquinoline derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the active substance
US6846492B2 (en) 2000-02-23 2005-01-25 Ciba Specialty Chemicals Corporation Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces
WO2001062082A2 (en) * 2000-02-23 2001-08-30 Ciba Specialty Chemicals Holding Inc. Use of phenylethylamine derivatives for the anitmicrobial treatment of surfaces
AU2002357728A1 (en) * 2001-11-09 2003-05-19 The Regents Of The University Of California Alpha-helix mimicry by a class of organic molecules
DE10229762A1 (de) * 2002-07-03 2004-01-22 Aventis Pharma Deutschland Gmbh Pyrazoloisoquinolinenderivaten zur Inhibierung von NFkappaB-induzierende Kinase
CN100386319C (zh) * 2005-12-05 2008-05-07 中国人民解放军第二军医大学 具有抗生育和抗真菌活性的四氢异喹啉类化合物或其盐类
EP2345642A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents
CZ302637B6 (cs) * 2010-01-05 2011-08-10 Zentiva, K. S Zpusob prípravy 6,7-dimethoxy-1-[2-(4-trifluormethylfenyl)ethyl]-3,4-dihydroisochinolinu

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3067203A (en) * 1962-12-04 Tetrahybroisqquinoline derivatives
GB862052A (en) * 1958-09-04 1961-03-01 Hoffmann La Roche Novel isoquinoline derivatives and salts thereof and a process for the manufacture of same
US3146266A (en) * 1959-08-25 1964-08-25 Hoffmann La Roche Novel ketone compounds
GB1181959A (en) * 1969-01-30 1970-02-18 Dresden Arzneimittel 6,7-Dimethoxy-3,4-Dihydroisoquinoline Derivatives
GB1386076A (en) * 1971-06-03 1975-03-05 Wyeth John & Brother Ltd Isoquinoline derivatives

Also Published As

Publication number Publication date
FI86848C (fi) 1992-10-26
PH27347A (en) 1993-06-08
EP0170524B1 (en) 1992-07-15
IL75978A (en) 1989-09-10
PL254779A1 (en) 1986-12-30
ES545775A0 (es) 1986-12-01
DE3586340T2 (de) 1993-03-04
EP0170524A3 (en) 1988-05-25
JPS6187665A (ja) 1986-05-06
EP0170524A2 (en) 1986-02-05
GB8419658D0 (en) 1984-09-05
ES8701730A1 (es) 1986-12-01
CA1291993C (en) 1991-11-12
US4968698A (en) 1990-11-06
ES8802222A1 (es) 1988-04-16
AU4566285A (en) 1986-02-06
FI852959A0 (fi) 1985-07-31
ES554635A0 (es) 1988-05-16
NZ212929A (en) 1989-05-29
DE3586340D1 (de) 1992-08-20
CS266332B2 (en) 1989-12-13
DK347685D0 (da) 1985-07-31
PT80893B (pt) 1987-11-30
JPH07252154A (ja) 1995-10-03
FI86848B (fi) 1992-07-15
HU194834B (en) 1988-03-28
IL75978A0 (en) 1985-12-31
DK347685A (da) 1986-02-02
KR860001791A (ko) 1986-03-22
ES8802382A1 (es) 1988-05-16
HUT40084A (en) 1986-11-28
KR920004484B1 (ko) 1992-06-05
FI852959L (fi) 1986-02-02
IE58661B1 (en) 1993-11-03
IE851903L (en) 1986-02-01
ATE78163T1 (de) 1992-08-15
ES554636A0 (es) 1988-04-16
CN85106609A (zh) 1987-03-25
DD236525A5 (de) 1986-06-11
US4963562A (en) 1990-10-16
JPH0688903B2 (ja) 1994-11-09
PL147636B1 (en) 1989-07-31
ZA855800B (en) 1987-03-25
PT80893A (en) 1985-08-01
AU597564B2 (en) 1990-06-07
CS558285A2 (en) 1989-02-10
GR851879B (da) 1985-12-02

Similar Documents

Publication Publication Date Title
DK162519C (da) Dihydropyridazinonderivater og fremgangsmaade til fremstilling deraf samt farmaceutisk praeparat indeholdende forbindelserne
MC1693A1 (fr) Nouveaux composes,compositions les contenant et intermediaires pour leur preparation
BE890035A (fr) Nouveaux derives du 4h-1,2,4-triazole, leur preparation, leur application comme medicament, les compositions les renfermant et les intermediaires obtenus
IT8420358A0 (it) Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti.
PT77806B (fr) Procede de preparation de nouveaux derives de la benzylcarbamo-ylpyridine et de compositions herbicides les contenant
ZA825428B (en) New imidazole compounds,process for the preparation thereof and pharmaceutical compositions containing them
FR2502150B1 (fr) Nouveaux derives de l'imidazole et compositions fongicides les renfermant
PT81377A (fr) Procede de preparation de nouveaux derives du 2-cyano-benzimidazole et de compositions fongicides et acaricides les contenant
LU79157A1 (fr) Procede de preparation de nouveaux derives de l'oxadiazole-1,3,4 et de compositions fongicides les contenant
PT79546A (fr) Procede de preparation de nouveaux derives de l'acide 2-(3-pyridyl)-2-phenylamino-acetique et de compositions antifongiques les contenant
PT84883A (fr) Procede de preparation de nouveaux derives nicotiniques et de compositions fongicides les contenant
BE894630A (fr) Nouveaux derives de 20, 21-dinoreburnamenine eventuellement substitues sur le cycle e, procede et intermediaires de preparation, application comme medicament et compositions les renferment
FR2558155B1 (fr) Derives du phenoxy-benzaldehyde, procede pour leur preparation et composition fongicide les contenant
PT69350A (fr) Procede de preparation de nouveaux derives de la phenyl-2 dihydro-5,6 pyrone-4 et de compositions herbicides les contenant
BE885127A (fr) Nouveaux derives de 1-phenethylimidazole, composition pharmaceutique les contenant et compose intermediaire pour leur preparation
PT73984B (fr) Procede de preparation de nouveaux derives de la dihydro-2,3 pyrone-4 et de compositions herbicides les contenant
FR2564463B1 (fr) Nouveaux derives heterocycliques, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase

Legal Events

Date Code Title Description
YP Annual fee paid