US4044126A
(en)
|
1972-04-20 |
1977-08-23 |
Allen & Hanburys Limited |
Steroidal aerosol compositions and process for the preparation thereof
|
GB1429184A
(en)
|
1972-04-20 |
1976-03-24 |
Allen & Hanburys Ltd |
Physically anti-inflammatory steroids for use in aerosols
|
US4444887A
(en)
|
1979-12-10 |
1984-04-24 |
Sloan-Kettering Institute |
Process for making human antibody producing B-lymphocytes
|
US4716111A
(en)
|
1982-08-11 |
1987-12-29 |
Trustees Of Boston University |
Process for producing human antibodies
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
WO1986005807A1
(fr)
|
1985-04-01 |
1986-10-09 |
Celltech Limited |
Lignee cellulaire de myelomes transformee et procede d'expression d'un gene codant un polypeptide eucaryotque employant cette lignee
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
US5869620A
(en)
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
DE3883899T3
(de)
|
1987-03-18 |
1999-04-22 |
Sb2, Inc., Danville, Calif. |
Geänderte antikörper.
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
EP0768377A1
(fr)
|
1988-09-02 |
1997-04-16 |
Protein Engineering Corporation |
Production et sélection de protéines de liaison diversifiées de recombinaison
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US5413923A
(en)
|
1989-07-25 |
1995-05-09 |
Cell Genesys, Inc. |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
US5585112A
(en)
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
AU7247191A
(en)
|
1990-01-11 |
1991-08-05 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
EP0463151B1
(fr)
|
1990-01-12 |
1996-06-12 |
Cell Genesys, Inc. |
Generation d'anticorps xenogeniques
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
IT1246382B
(it)
|
1990-04-17 |
1994-11-18 |
Eurand Int |
Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
DE69127627T2
(de)
|
1990-08-29 |
1998-02-19 |
Genpharm Int |
Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
US5543390A
(en)
|
1990-11-01 |
1996-08-06 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University |
Covalent microparticle-drug conjugates for biological targeting
|
ES2113940T3
(es)
|
1990-12-03 |
1998-05-16 |
Genentech Inc |
Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
|
CA2108147C
(fr)
|
1991-04-10 |
2009-01-06 |
Angray Kang |
Banques de recepteurs heterodimeriques construites a l'aide de phagemides
|
EP0519596B1
(fr)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
Procédé pour réduire l'immunogénicité des domaines variables d'anticorps
|
DK0590058T3
(da)
|
1991-06-14 |
2004-03-29 |
Genentech Inc |
Humaniseret heregulin-antistof
|
EP0590067A1
(fr)
|
1991-06-14 |
1994-04-06 |
Xoma Corporation |
Fragments d'anticorps produits par des microbes et leurs conjugues
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
ATE463573T1
(de)
|
1991-12-02 |
2010-04-15 |
Medimmune Ltd |
Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
|
EP0571613B1
(fr)
|
1991-12-13 |
2003-09-17 |
Xoma Corporation |
Materiels et methodes pour preparer des domaines variables d'anticorps modifies et leurs utilisations therapeutiques
|
GB9203459D0
(en)
|
1992-02-19 |
1992-04-08 |
Scotgen Ltd |
Antibodies with germ-line variable regions
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
GB9206422D0
(en)
|
1992-03-24 |
1992-05-06 |
Bolt Sarah L |
Antibody preparation
|
US6174666B1
(en)
|
1992-03-27 |
2001-01-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method of eliminating inhibitory/instability regions from mRNA
|
US6010715A
(en)
|
1992-04-01 |
2000-01-04 |
Bertek, Inc. |
Transdermal patch incorporating a polymer film incorporated with an active agent
|
US6024975A
(en)
|
1992-04-08 |
2000-02-15 |
Americare International Diagnostics, Inc. |
Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
|
CA2118508A1
(fr)
|
1992-04-24 |
1993-11-11 |
Elizabeth S. Ward |
Production par recombinaison genetique de domaines semblables aux immunoglobulines dans les cellules procaryotes
|
US6005079A
(en)
|
1992-08-21 |
1999-12-21 |
Vrije Universiteit Brussels |
Immunoglobulins devoid of light chains
|
ATE427968T1
(de)
|
1992-08-21 |
2009-04-15 |
Univ Bruxelles |
Immunoglobuline ohne leichtkette
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
EP0672142B1
(fr)
|
1992-12-04 |
2001-02-28 |
Medical Research Council |
Proteines de liaison multivalentes et multispecifiques, leur fabrication et leur utilisation
|
US6274552B1
(en)
|
1993-03-18 |
2001-08-14 |
Cytimmune Sciences, Inc. |
Composition and method for delivery of biologically-active factors
|
US5523092A
(en)
|
1993-04-14 |
1996-06-04 |
Emory University |
Device for local drug delivery and methods for using the same
|
US5985307A
(en)
|
1993-04-14 |
1999-11-16 |
Emory University |
Device and method for non-occlusive localized drug delivery
|
WO1994025591A1
(fr)
|
1993-04-29 |
1994-11-10 |
Unilever N.V. |
PRODUCTION D'ANTICORPS OU DE FRAGMENTS FONCTIONNALISES D'ANTICORPS, DERIVES DES IMMUNOGLOBULINES A CHAINE LOURDE DE $i(CAMELIDAE)
|
AU691811B2
(en)
|
1993-06-16 |
1998-05-28 |
Celltech Therapeutics Limited |
Antibodies
|
US6004534A
(en)
|
1993-07-23 |
1999-12-21 |
Massachusetts Institute Of Technology |
Targeted polymerized liposomes for improved drug delivery
|
EP0733070A1
(fr)
|
1993-12-08 |
1996-09-25 |
Genzyme Corporation |
Procede de generation d'anticorps specifiques
|
GB9326253D0
(en)
|
1993-12-23 |
1994-02-23 |
Smithkline Beecham Biolog |
Vaccines
|
US5997873A
(en)
|
1994-01-13 |
1999-12-07 |
Mount Sinai School Of Medicine Of The City University Of New York |
Method of preparation of heat shock protein 70-peptide complexes
|
ES2247204T3
(es)
|
1994-01-31 |
2006-03-01 |
Trustees Of Boston University |
Bancos de anticuerpos policlonales.
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
US5759542A
(en)
|
1994-08-05 |
1998-06-02 |
New England Deaconess Hospital Corporation |
Compositions and methods for the delivery of drugs by platelets for the treatment of cardiovascular and other diseases
|
US5660854A
(en)
|
1994-11-28 |
1997-08-26 |
Haynes; Duncan H |
Drug releasing surgical implant or dressing material
|
US6066322A
(en)
|
1995-03-03 |
2000-05-23 |
Millennium Pharmaceuticals, Inc. |
Methods for the treatment of immune disorders
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US5983134A
(en)
|
1995-04-23 |
1999-11-09 |
Electromagnetic Bracing Systems Inc. |
Electrophoretic cuff apparatus drug delivery system
|
EP1978033A3
(fr)
|
1995-04-27 |
2008-12-24 |
Amgen Fremont Inc. |
Anticorps humains dérivés à partir de xénosouris immunisée
|
AU2466895A
(en)
|
1995-04-28 |
1996-11-18 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US6316652B1
(en)
|
1995-06-06 |
2001-11-13 |
Kosta Steliou |
Drug mitochondrial targeting agents
|
US6167301A
(en)
|
1995-08-29 |
2000-12-26 |
Flower; Ronald J. |
Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
|
US5935576A
(en)
|
1995-09-13 |
1999-08-10 |
Fordham University |
Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens
|
GB9601081D0
(en)
|
1995-10-06 |
1996-03-20 |
Cambridge Antibody Tech |
Specific binding members for human transforming growth factor beta;materials and methods
|
AU6873396A
(en)
|
1995-10-16 |
1997-05-07 |
Unilever N.V. |
A bifunctional or bivalent antibody fragment analogue
|
US6039975A
(en)
|
1995-10-17 |
2000-03-21 |
Hoffman-La Roche Inc. |
Colon targeted delivery system
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
CA2249195A1
(fr)
|
1996-03-18 |
1997-09-25 |
Board Of Regents, The University Of Texas System |
Domaines analogues a l'immunoglobuline a demi-vies prolongees
|
TW345603B
(en)
|
1996-05-29 |
1998-11-21 |
Gmundner Fertigteile Gmbh |
A noise control device for tracks
|
US6027947A
(en)
|
1996-08-20 |
2000-02-22 |
Ramtron International Corporation |
Partially or completely encapsulated top electrode of a ferroelectric capacitor
|
US5985317A
(en)
|
1996-09-06 |
1999-11-16 |
Theratech, Inc. |
Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
|
HUP0000116A3
(en)
|
1996-10-01 |
2000-08-28 |
Stanford Res Inst Int |
Taste-masked microcapsule compositions and methods of manufacture
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
US6131570A
(en)
|
1998-06-30 |
2000-10-17 |
Aradigm Corporation |
Temperature controlling device for aerosol drug delivery
|
WO1998023289A1
(fr)
|
1996-11-27 |
1998-06-04 |
The General Hospital Corporation |
Modulation de la fixation de l'igg au fcrn
|
EP1500329B1
(fr)
|
1996-12-03 |
2012-03-21 |
Amgen Fremont Inc. |
Les anticorps humains qui lient en particulier l'alpha de TNF humain
|
US6017540A
(en)
|
1997-02-07 |
2000-01-25 |
Fordham University |
Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
|
US5860957A
(en)
|
1997-02-07 |
1999-01-19 |
Sarcos, Inc. |
Multipathway electronically-controlled drug delivery system
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
EP0970126B1
(fr)
|
1997-04-14 |
2001-04-18 |
Micromet AG |
Nouveau procede de production de recepteurs d'anti-antigenes humains et leur utilisation
|
US6060082A
(en)
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
US7951917B1
(en)
|
1997-05-02 |
2011-05-31 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
US5948433A
(en)
|
1997-08-21 |
1999-09-07 |
Bertek, Inc. |
Transdermal patch
|
ATE435661T1
(de)
|
1997-08-29 |
2009-07-15 |
Antigenics Inc |
Adjuvant qs-21 enthaltende zusammensetzungen mit polysorbate oder cyclodextrin als hilfsmittel
|
CN1152673C
(zh)
|
1997-10-28 |
2004-06-09 |
坂东化学株式会社 |
皮肤贴附药片及其基片的制造方法
|
US5948646A
(en)
|
1997-12-11 |
1999-09-07 |
Fordham University |
Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
US6048736A
(en)
|
1998-04-29 |
2000-04-11 |
Kosak; Kenneth M. |
Cyclodextrin polymers for carrying and releasing drugs
|
DK1104306T3
(da)
|
1998-08-10 |
2006-05-22 |
Antigenics Inc |
Præparater af CpG- og saponinadjuvanser og fremgangsmåder til anvendelse deraf
|
KR101077001B1
(ko)
|
1999-01-15 |
2011-10-26 |
제넨테크, 인크. |
효과기 기능이 변화된 폴리펩티드 변이체
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
US6271359B1
(en)
|
1999-04-14 |
2001-08-07 |
Musc Foundation For Research Development |
Tissue-specific and pathogen-specific toxic agents and ribozymes
|
WO2000073498A1
(fr)
|
1999-06-02 |
2000-12-07 |
Millennium Pharmaceuticals, Inc. |
Compositions et procede pour le traitement et le diagnostic de troubles de l'immunite
|
US6256533B1
(en)
|
1999-06-09 |
2001-07-03 |
The Procter & Gamble Company |
Apparatus and method for using an intracutaneous microneedle array
|
PT1210428E
(pt)
|
1999-08-23 |
2015-07-21 |
Genetics Inst Llc |
Pd-1, um recetor para b7-4 e suas utilizações
|
DE60042789D1
(de)
|
1999-11-29 |
2009-10-01 |
Bac Ip B V |
Immobilisierte antigenbindende moleküle aus einer domäne
|
DK1234031T3
(en)
|
1999-11-30 |
2017-07-03 |
Mayo Foundation |
B7-H1, AN UNKNOWN IMMUNE REGULATORY MOLECULE
|
EP1125905A1
(fr)
|
2000-02-16 |
2001-08-22 |
Pepscan Systems B.V. |
Synthèse de segments
|
US6261595B1
(en)
|
2000-02-29 |
2001-07-17 |
Zars, Inc. |
Transdermal drug patch with attached pocket for controlled heating device
|
EP1272647B1
(fr)
|
2000-04-11 |
2014-11-12 |
Genentech, Inc. |
Anticorps multivalents et leurs utilisations
|
EP1197755A1
(fr)
|
2000-10-11 |
2002-04-17 |
Pepscan Systems B.V. |
Identification de sites de liaison de protéines
|
US7658921B2
(en)
|
2000-12-12 |
2010-02-09 |
Medimmune, Llc |
Molecules with extended half-lives, compositions and uses thereof
|
EP1355919B1
(fr)
|
2000-12-12 |
2010-11-24 |
MedImmune, LLC |
Molecules a demi-vies longues, compositions et utilisations de celles-ci
|
JP2004537032A
(ja)
|
2001-02-16 |
2004-12-09 |
ペプスキャン システムズ ベー.フェー. |
ピクセルアレイ
|
US8709412B2
(en)
|
2001-06-29 |
2014-04-29 |
The Board Of Trustees Of The Leland Stanford Junior University |
Modulation of TIM receptor activity in combination with cytoreductive therapy
|
US7838220B2
(en)
|
2001-06-29 |
2010-11-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
T cell regulatory genes associated with immune disease
|
EP1406653A4
(fr)
|
2001-06-29 |
2005-05-04 |
Univ Leland Stanford Junior |
Genes regulateurs de lymphocytes t et leurs methodes d'utilisation
|
MXPA05000511A
(es)
|
2001-07-12 |
2005-09-30 |
Jefferson Foote |
Anticuepros super humanizados.
|
EP1456652A4
(fr)
|
2001-11-13 |
2005-11-02 |
Dana Farber Cancer Inst Inc |
Agents modulant l'activite de cellules immunes et procedes d'utilisation associes
|
JP4694128B2
(ja)
|
2002-01-30 |
2011-06-08 |
ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド |
TIM−3、Th1特異的細胞表面分子に関連した組成物および方法
|
US20040014194A1
(en)
|
2002-03-27 |
2004-01-22 |
Schering Corporation |
Beta-secretase crystals and methods for preparing and using the same
|
IL149820A0
(en)
|
2002-05-23 |
2002-11-10 |
Curetech Ltd |
Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
|
JP4409430B2
(ja)
|
2002-07-03 |
2010-02-03 |
小野薬品工業株式会社 |
免疫賦活組成物
|
JP4511943B2
(ja)
|
2002-12-23 |
2010-07-28 |
ワイス エルエルシー |
Pd−1に対する抗体およびその使用
|
US9068234B2
(en)
|
2003-01-21 |
2015-06-30 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating gene expression
|
US20050042664A1
(en)
|
2003-08-22 |
2005-02-24 |
Medimmune, Inc. |
Humanization of antibodies
|
US20050208627A1
(en)
|
2003-09-18 |
2005-09-22 |
Bowdish Katherine S |
Elicitation of antibodies to self peptides in mice by immunization with dendritic cells
|
US20070054378A1
(en)
|
2003-09-18 |
2007-03-08 |
Alexion Pharmaceuticals, Inc. |
Elicitation of antibodies to self peptides in mice by immunization with dendritic cells
|
US8329660B2
(en)
|
2003-10-03 |
2012-12-11 |
The Brigham And Women's Hospital, Inc. |
Tim-3 ligands and methods thereof
|
CN101035561A
(zh)
|
2004-03-24 |
2007-09-12 |
特罗斯药品公司 |
作为改善对疫苗的免疫反应的佐剂的组合物和使用方法
|
EP1740224A4
(fr)
|
2004-03-24 |
2008-07-02 |
Telos Pharmaceuticals Llc |
Compositions adjuvantes ameliorant la reponse immunitaire a des vaccins et methodes d'utilisation
|
US20090304679A1
(en)
|
2004-05-27 |
2009-12-10 |
Weidanz Jon A |
Antibodies as T cell receptor mimics, methods of production and uses thereof
|
KR20070034588A
(ko)
|
2004-06-14 |
2007-03-28 |
더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 |
Cd34+/cd36+ 태아 세포에는 결합하지만 성체세포에는 결합하지 않는 항체
|
PL2439273T3
(pl)
|
2005-05-09 |
2019-08-30 |
Ono Pharmaceutical Co., Ltd. |
Ludzkie przeciwciała monoklonalne przeciwko białku programowanej śmierci komórki 1(pd-1) oraz metody leczenia nowotworów z wykorzystaniem przeciwciał anty-pd-1 samodzielnie lub w połączeniu z innymi immunoterapeutykami
|
CN104356236B
(zh)
|
2005-07-01 |
2020-07-03 |
E.R.施贵宝&圣斯有限责任公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
CA2618482C
(fr)
|
2005-08-19 |
2014-10-07 |
Abbott Laboratories |
Immunoglobuline a deux domaines variables et utilisations de celle-ci
|
EP2418223A3
(fr)
|
2006-06-12 |
2013-01-16 |
Emergent Product Development Seattle, LLC |
Protéines de liaison polyvalente à chaîne unique avec une fonction effectrice
|
AU2007319806A1
(en)
|
2006-11-15 |
2008-05-22 |
The Brigham And Women's Hospital, Inc. |
Therapeutic uses of TIM-3 modulators
|
US8907065B2
(en)
|
2006-12-15 |
2014-12-09 |
Ablynx N.V. |
Polypeptides that modulate the interaction between cells of the immune system
|
WO2008138017A2
(fr)
|
2007-05-08 |
2008-11-13 |
Beth Israel Deaconess Medical Center, Inc. |
Procédés et compositions permettant de modifier des réponses immunitaires de lymphocyte t et l'inflammation
|
CN103641919B
(zh)
|
2007-05-30 |
2017-04-05 |
浦项工科大学校产学协力团 |
免疫球蛋白融合蛋白
|
CA2691357C
(fr)
|
2007-06-18 |
2014-09-23 |
N.V. Organon |
Anticorps diriges contre le recepteur humain de mort programmee pd-1
|
JP5932217B2
(ja)
|
2007-07-12 |
2016-06-08 |
ジーアイティーアール, インコーポレイテッド |
Gitr結合分子を使用する併用療法
|
WO2009052623A1
(fr)
|
2007-10-26 |
2009-04-30 |
Governing Council Of The University Of Toronto |
Méthodes thérapeutiques et diagnostiques utilisant le tim-3
|
WO2009064290A1
(fr)
|
2007-11-13 |
2009-05-22 |
Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services |
Structure d'éléments de la famille tim
|
US8227577B2
(en)
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
ES2796085T3
(es)
|
2008-01-15 |
2020-11-25 |
Univ Leland Stanford Junior |
Marcadores de células madre de leucemia mieloide aguda
|
US20110059106A1
(en)
|
2008-01-29 |
2011-03-10 |
Brigham And Women's Hospital, Inc. |
Methods for modulating a population of myeloid-derived suppressor cells and uses thereof
|
CN104548091A
(zh)
|
2008-02-11 |
2015-04-29 |
治疗科技公司 |
用于肿瘤治疗的单克隆抗体
|
WO2009114335A2
(fr)
|
2008-03-12 |
2009-09-17 |
Merck & Co., Inc. |
Protéines de liaison avec pd-1
|
JP2011515497A
(ja)
|
2008-03-26 |
2011-05-19 |
セレラント セラピューティクス インコーポレイテッド |
骨髄性血液学的増殖性疾患と関連する免疫グロブリンおよび/またはToll様受容体タンパク質ならびにその使用
|
WO2009131572A1
(fr)
|
2008-04-22 |
2009-10-29 |
Government Of The U.S. As Represented By The Secretary Of The Department Of Health And Human Service |
Structure de membres de la famille tim
|
EA029781B1
(ru)
|
2008-07-08 |
2018-05-31 |
Инсайт Корпорейшн |
1,2,5-оксадиазолы в качестве ингибиторов индоламин-2,3-диоксигеназы
|
EA023148B1
(ru)
|
2008-08-25 |
2016-04-29 |
Эмплиммьюн, Инк. |
Композиции на основе антагонистов pd-1 и их применение
|
US8927697B2
(en)
|
2008-09-12 |
2015-01-06 |
Isis Innovation Limited |
PD-1 specific antibodies and uses thereof
|
CA2998281C
(fr)
|
2008-09-26 |
2022-08-16 |
Dana-Farber Cancer Institute, Inc. |
Anticorps anti-pd-1 humains et leurs utilisations
|
EP4169951A1
(fr)
|
2008-12-09 |
2023-04-26 |
F. Hoffmann-La Roche AG |
Anticorps anti-pd-l1 et leur utilisation pour améliorer la fonction des lymphocytes t
|
WO2010084999A1
(fr)
|
2009-01-26 |
2010-07-29 |
Protegene, Inc. |
Agents immunosuppresseurs et agents prophylactiques et thérapeutiques pour des maladies auto-immunes
|
US20120070450A1
(en)
|
2009-03-24 |
2012-03-22 |
Riken |
Leukemia stem cell markers
|
WO2010117057A1
(fr)
|
2009-04-10 |
2010-10-14 |
協和発酵キリン株式会社 |
Procédé pour le traitement d'une tumeur sanguine utilisant un anticorps anti-tim-3
|
KR20120027055A
(ko)
|
2009-06-26 |
2012-03-20 |
리제네론 파라마큐티칼스 인코포레이티드 |
천연 면역글로불린 포맷을 가지는 용이하게 분리된 이중특이성 항체
|
PL2477648T3
(pl)
|
2009-09-15 |
2022-11-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Synergistyczna terapia anty-cd47 dla nowotworów hematologicznych
|
CN104961829B
(zh)
|
2009-11-24 |
2018-08-21 |
米迪缪尼有限公司 |
针对b7-h1的靶向结合剂
|
WO2011100841A1
(fr)
|
2010-02-16 |
2011-08-25 |
Valorisation-Recherche, Limited Partnership |
Modulation de pd-1 et utilisations de celle-ci pour moduler la réplication du vih
|
PT2542590T
(pt)
|
2010-03-05 |
2017-08-31 |
Univ Johns Hopkins |
Composições e métodos para anticorpos e proteínas de fusão imunomoduladores direcionados
|
US8993731B2
(en)
|
2010-03-11 |
2015-03-31 |
Ucb Biopharma Sprl |
PD-1 antibody
|
JP6158511B2
(ja)
*
|
2010-06-11 |
2017-07-05 |
協和発酵キリン株式会社 |
抗tim−3抗体
|
WO2011159877A2
(fr)
|
2010-06-18 |
2011-12-22 |
The Brigham And Women's Hospital, Inc. |
Anticorps di-spécifiques anti-tim-3 et pd-1 pour immunothérapie dans des états pathologiques immuns chroniques
|
WO2012088302A2
(fr)
|
2010-12-22 |
2012-06-28 |
Abbott Laboratories |
Protéines de liaison à une demi-immunoglobuline et leurs utilisations
|
US20120195900A1
(en)
|
2010-12-22 |
2012-08-02 |
Abbott Laboratories |
Tri-variable domain binding proteins and uses thereof
|
US9555108B2
(en)
|
2011-03-24 |
2017-01-31 |
Texas Tech University System |
TCR mimic antibodies as vascular targeting tools
|
SG193956A1
(en)
|
2011-04-01 |
2013-11-29 |
Sloan Kettering Inst Cancer |
T cell receptor-like antibodies specific for a wt1 peptide presented by hla-a2
|
WO2012145493A1
(fr)
|
2011-04-20 |
2012-10-26 |
Amplimmune, Inc. |
Anticorps et autres molécules qui se lient à b7-h1 et à pd-1
|
WO2012177788A1
(fr)
|
2011-06-20 |
2012-12-27 |
La Jolla Institute For Allergy And Immunology |
Modulateurs de 4-1bb et réponses immunitaires
|
AU2012273182A1
(en)
|
2011-06-21 |
2014-01-16 |
The Johns Hopkins University |
Focused radiation for augmenting immune-based therapies against neoplasms
|
WO2013006490A2
(fr)
|
2011-07-01 |
2013-01-10 |
Cellerant Therapeutics, Inc. |
Anticorps se liant spécifiquement à tim3
|
LT2734551T
(lt)
|
2011-07-24 |
2018-04-10 |
Cure Tech Ltd. |
Humanizuotų imunomoduliuojančių monokloninių antikūnų variantai
|
US8920075B2
(en)
|
2011-09-01 |
2014-12-30 |
Halo Maritime Defense Systems, Inc. |
Marine barrier and gate
|
CN102490238A
(zh)
*
|
2011-11-23 |
2012-06-13 |
东北林业大学 |
玉米秸秆皮瓤的分离方法
|
SG11201402603WA
(en)
|
2011-11-28 |
2014-06-27 |
Merck Patent Gmbh |
Anti-pd-l1 antibodies and uses thereof
|
CN102492038B
(zh)
*
|
2011-12-09 |
2014-05-28 |
中国人民解放军军事医学科学院基础医学研究所 |
抗人Tim-3的中和性单克隆抗体L3D及其用途
|
IN2014KN00848A
(fr)
|
2012-02-01 |
2015-10-02 |
Compugen Ltd |
|
BR112014021068A8
(pt)
|
2012-02-21 |
2018-01-23 |
Centre National De La Recherce Scient |
inibidor de uma interação entre fosfatidilserina e um receptor tim, composição farmacêutica e uso de um inibidor
|
EP2817619B1
(fr)
|
2012-02-23 |
2018-07-25 |
Sloan Kettering Institute For Cancer Research |
Prédiction de la sensibilité à un traitement par des produits thérapeutiques d'immunomodulation et procédé de surveillance des effets ascopaux au cours d'un tel traitement
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
WO2013181634A2
(fr)
|
2012-05-31 |
2013-12-05 |
Sorrento Therapeutics Inc. |
Protéines liant un antigène qui lient pd-l1
|
BR112015000167B1
(pt)
|
2012-07-06 |
2021-11-23 |
Genmab B.V. |
Proteína dimérica, proteína, composição, kit de partes e seus usos, bem como método para aumentar a oligomerização em solução de uma proteína dimérica compreendendo um primeiro e segundo polipeptídeo, cada um compreendendo pelo menos as regiões ch2 e ch3 de uma cadeia pesada de igg1 humana e proteína dimérica variante
|
CN112587671A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
JP2015523412A
(ja)
|
2012-07-30 |
2015-08-13 |
ワウ ヒン イェウング,アレックス |
腫瘍細胞、GM‐CSFのトランスジェニック発現を伴う腫瘍溶解性ウイルスベクター、および免疫チェックポイントモジュレーターなどの成分の少なくとも2種または全3種の同時投与により作られる生のinvivo腫瘍特異的がんワクチンシステム
|
US10513540B2
(en)
|
2012-07-31 |
2019-12-24 |
The Brigham And Women's Hospital, Inc. |
Modulation of the immune response
|
US9845356B2
(en)
|
2012-08-03 |
2017-12-19 |
Dana-Farber Cancer Institute, Inc. |
Single agent anti-PD-L1 and PD-L2 dual binding antibodies and methods of use
|
MX370848B
(es)
|
2012-10-04 |
2020-01-08 |
Dana Farber Cancer Inst Inc |
Anticuerpos monoclonales humanos anti-pd-l1 y métodos de uso.
|
JP2016500251A
(ja)
|
2012-12-03 |
2016-01-12 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
免疫調節Fc融合タンパク質の抗癌活性の増強
|
EP2931317A2
(fr)
|
2012-12-13 |
2015-10-21 |
Children's Medical Center Corporation |
Compositions et procédés pour inhiber l'entrée virale
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
DK2992017T3
(da)
|
2013-05-02 |
2021-01-25 |
Anaptysbio Inc |
Antistoffer rettet mod programmeret død-1 (pd-1)
|
CN105683217B
(zh)
|
2013-05-31 |
2019-12-10 |
索伦托治疗有限公司 |
与pd-1结合的抗原结合蛋白
|
US20160145355A1
(en)
|
2013-06-24 |
2016-05-26 |
Biomed Valley Discoveries, Inc. |
Bispecific antibodies
|
CN104250302B
(zh)
|
2013-06-26 |
2017-11-14 |
上海君实生物医药科技股份有限公司 |
抗pd‑1抗体及其应用
|
MX2016000750A
(es)
|
2013-08-02 |
2016-08-05 |
Aduro Biotech Holdings Europe B V |
Combinacion de agonistas de cd27 e inhibicion del punto de control inmunologico para estimulacion del sistema inmunologico.
|
WO2015035112A1
(fr)
|
2013-09-05 |
2015-03-12 |
The Johns Hopkins University |
Thérapie anticancéreuse par l'intermédiaire d'une combinaison de modulation épigénétique et modulation immunitaire
|
WO2015036394A1
(fr)
|
2013-09-10 |
2015-03-19 |
Medimmune Limited |
Anticorps contre pd-1 et leurs utilisations
|
JP6623353B2
(ja)
|
2013-09-13 |
2019-12-25 |
ベイジーン スウィッツァーランド ゲーエムベーハー |
抗pd−1抗体並びにその治療及び診断のための使用
|
EP3757130A1
(fr)
|
2013-09-26 |
2020-12-30 |
Costim Pharmaceuticals Inc. |
Méthodes de traitement de cancers hématologiques
|
EA201690746A1
(ru)
|
2013-10-25 |
2016-12-30 |
Фармасайкликс Элэлси |
Лечение с применением ингибиторов тирозинкиназы брутона и иммунотерапии
|
CN104558177B
(zh)
|
2013-10-25 |
2020-02-18 |
苏州思坦维生物技术股份有限公司 |
拮抗抑制程序性死亡受体pd-1与其配体结合的单克隆抗体及其编码序列与用途
|
WO2015061668A1
(fr)
|
2013-10-25 |
2015-04-30 |
Dana-Farber Cancer Institute, Inc. |
Anticorps monoclonaux anti-pd-l1 et fragments de ceux-ci
|
IL292510A
(en)
|
2013-11-05 |
2022-06-01 |
Cognate Bioservices Inc |
Combinations of checkpoint inhibitors and cancer drugs
|
DK3081576T3
(da)
|
2013-12-12 |
2019-10-21 |
Shanghai hengrui pharmaceutical co ltd |
Pd-1-antistof, antigenbindende fragment deraf og medicinsk anvendelse deraf
|
GB201322725D0
(en)
|
2013-12-20 |
2014-02-05 |
Immodulon Therapeutics Ltd |
Cancer therapy
|
JP6590810B2
(ja)
|
2013-12-24 |
2019-10-16 |
ヤンセン ファーマシューティカ エヌブイ |
抗vista抗体および断片
|
HRP20220214T1
(hr)
|
2014-01-15 |
2022-04-29 |
Kadmon Corporation, Llc |
Imunomodulacijska sredstva
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
JOP20200096A1
(ar)
*
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
JP2017507931A
(ja)
|
2014-02-05 |
2017-03-23 |
シーダーズ−サイナイ メディカル センター |
がん及び感染症の治療方法並びに治療用組成物
|
BR112016014952A2
(pt)
|
2014-02-10 |
2017-09-19 |
Merck Patent Gmbh |
Inibição direcionada de tgfbeta
|
US10144778B2
(en)
|
2014-03-12 |
2018-12-04 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
WO2017042633A2
(fr)
|
2015-09-10 |
2017-03-16 |
Yeda Research And Development Co. Ltd |
Réduction des quantités ou de l'activité de cellules t régulatrices systémiques pour le traitement de maladie et de lésion du snc
|
WO2015142675A2
(fr)
|
2014-03-15 |
2015-09-24 |
Novartis Ag |
Traitement du cancer au moyen d'un récepteur antigénique chimérique
|
WO2015155738A2
(fr)
|
2014-04-09 |
2015-10-15 |
Christopher Rudd |
Utilisation d'inhibiteurs ou d'activateurs de gsk -3 qui modulent l'expression de pd -1 ou de t-bet pour moduler l'immunité due aux lymphocytes t
|
EP2939690A1
(fr)
|
2014-04-29 |
2015-11-04 |
Medizinische Hochschule Hannover |
Vaccins
|
CN107073090A
(zh)
|
2014-04-30 |
2017-08-18 |
哈佛学院董事会 |
结合的疫苗装置和杀死癌细胞的方法
|
US11505605B2
(en)
|
2014-05-13 |
2022-11-22 |
Chugai Seiyaku Kabushiki Kaisha |
T cell-redirected antigen-binding molecule for cells having immunosuppression function
|
CN108064242B
(zh)
*
|
2014-05-28 |
2022-10-21 |
阿吉纳斯公司 |
抗gitr抗体和其使用方法
|
WO2015181342A1
(fr)
|
2014-05-29 |
2015-12-03 |
Spring Bioscience Corporation |
Anticorps dirigés contre pd-l1 et leurs utilisations
|
WO2015195163A1
(fr)
|
2014-06-20 |
2015-12-23 |
R-Pharm Overseas, Inc. |
Anticorps totalement humain anti-pd-l1
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
WO2015197874A2
(fr)
|
2014-06-27 |
2015-12-30 |
Apogenix Gmbh |
Combinaison d'inhibition du cd95/cd95l et d'immunothérapie du cancer
|
WO2015200828A1
(fr)
|
2014-06-27 |
2015-12-30 |
H. Lee Moffit Cancer Center And Research Institute, Inc. |
Conjugués pour immunothérapie
|
KR102130600B1
(ko)
|
2014-07-03 |
2020-07-08 |
베이진 엘티디 |
Pd-l1 항체와 이를 이용한 치료 및 진단
|
AU2015287969B2
(en)
|
2014-07-07 |
2020-07-09 |
Dana-Farber Cancer Institute, Inc. |
Methods of treating cancer
|
CN105233291A
(zh)
|
2014-07-09 |
2016-01-13 |
博笛生物科技有限公司 |
用于治疗癌症的联合治疗组合物和联合治疗方法
|
KR102504758B1
(ko)
|
2014-07-16 |
2023-02-28 |
트랜스진 |
종양 세포 붕괴성 바이러스와 면역 체크포인트 조절제의 배합물
|
CN105330740B
(zh)
|
2014-07-30 |
2018-08-17 |
珠海市丽珠单抗生物技术有限公司 |
抗pd-1抗体及其应用
|
DK3177644T3
(da)
|
2014-08-05 |
2021-01-11 |
MabQuest SA |
Immunologiske reagenser, som binder til PD-1
|
WO2016020538A1
(fr)
|
2014-08-08 |
2016-02-11 |
Transgene Sa |
Traitement en association d'un vaccin contre le hbv et d'un anticorps pour traiter des infections à hbv.
|
EP4321171A3
(fr)
|
2014-08-08 |
2024-05-15 |
The Board of Trustees of the Leland Stanford Junior University |
Protéines de fusion sirp alpha-anticorps
|
WO2016025645A1
(fr)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Traitement tumoral synergique avec l'il-2, un anticorps thérapeutique, et un bloqueur de point de contrôle immunitaire
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
AU2015305754B2
(en)
|
2014-08-19 |
2018-10-25 |
Merck Sharp & Dohme Llc |
Anti-tigit antibodies
|
LT3186283T
(lt)
|
2014-08-29 |
2020-03-10 |
F. Hoffmann-La Roche Ag |
Kombinuotoji terapija į naviką nutaikytais il-2 imunocitokinais ir antikūnais prieš žmogaus pd-l1
|
EP3925622A1
(fr)
|
2014-09-13 |
2021-12-22 |
Novartis AG |
Polythérapies
|
US20170209574A1
(en)
|
2014-10-03 |
2017-07-27 |
Novartis Ag |
Combination therapies
|
CN115040532A
(zh)
|
2014-10-10 |
2022-09-13 |
伊黛拉制药有限公司 |
使用tlr9激动剂与检查点抑制剂对癌症的治疗
|
CA3003133C
(fr)
|
2014-10-24 |
2020-09-15 |
StemImmune, Incorporated |
Technique d'immunotherapie combinee pour le traitement du cancer
|
SG10201803042PA
(en)
*
|
2014-10-27 |
2018-06-28 |
Agency Science Tech & Res |
Anti-tim-3 antibodies
|
GB201419094D0
(en)
|
2014-10-27 |
2014-12-10 |
Agency Science Tech & Res |
Anti-TIM-3-antibodies
|
NZ731467A
(en)
*
|
2014-11-06 |
2021-12-24 |
Hoffmann La Roche |
Anti-tim3 antibodies and methods of use
|
KR20190135563A
(ko)
|
2014-11-13 |
2019-12-06 |
더 존스 홉킨스 유니버시티 |
관문 차단 및 미소부수체 불안정성
|
PL3789402T3
(pl)
|
2014-11-20 |
2022-10-17 |
F. Hoffmann-La Roche Ag |
Terapia skojarzona składająca się z dwuswoistych cząsteczek wiążących antygen aktywujących limfocyty T oraz antagonistów wiązania osi PD-1
|
PL3221346T3
(pl)
|
2014-11-21 |
2021-03-08 |
Bristol-Myers Squibb Company |
Przeciwciała ze zmodyfikowanym regionem stałym łańcucha ciężkiego
|
MA40737A
(fr)
|
2014-11-21 |
2017-07-04 |
Memorial Sloan Kettering Cancer Center |
Déterminants de la réponse d'un cancer à une immunothérapie par blocage de pd-1
|
MX2017007136A
(es)
|
2014-12-05 |
2017-12-04 |
Immunext Inc |
Identificacion de vsig8 como el receptor vista putativo y su uso para producir moduladores vista/vsig8.
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
US20170340733A1
(en)
|
2014-12-19 |
2017-11-30 |
Novartis Ag |
Combination therapies
|
US20160200815A1
(en)
|
2015-01-05 |
2016-07-14 |
Jounce Therapeutics, Inc. |
Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof
|
WO2016118654A1
(fr)
|
2015-01-20 |
2016-07-28 |
Immunexcite, Inc. |
Compositions et procédés pour immunothérapie de cancer
|
CA2974956A1
(fr)
|
2015-01-29 |
2016-08-04 |
The Trustees Of The University Of Pennsylvania |
Associations d'inhibiteurs de point de controle immunitaires et de vaccins, et leur utilisation en immunotherapie
|
JP6895380B2
(ja)
|
2015-02-06 |
2021-06-30 |
ナショナル ユニバーシティ オブ シンガポール |
治療免疫細胞の有効性を改良するための方法
|
EP3256156A1
(fr)
|
2015-02-13 |
2017-12-20 |
Transgene SA |
Vaccin immunothérapeutique et thérapie combinée à base d'anticorps
|
CN104592388B
(zh)
*
|
2015-03-02 |
2017-05-31 |
中国人民解放军总医院 |
一种抗人Tim‑3的单克隆抗体的抗原结合部分
|
JP2018510151A
(ja)
|
2015-03-06 |
2018-04-12 |
ソレント・セラピューティクス・インコーポレイテッド |
Tim3に結合する抗体医薬
|
EP3267969A1
(fr)
|
2015-03-09 |
2018-01-17 |
King's College London |
Polythérapie avec des agonistes alpha de rar pour améliorer une réponse de type th1
|
EP3271463A4
(fr)
|
2015-03-18 |
2018-08-01 |
Baylor College of Medicine |
Récepteur antigénique chimérique her2/erbb2
|
AU2016238290B9
(en)
|
2015-03-25 |
2019-06-13 |
The Regents Of The University Of Michigan |
Compositions and methods for delivery of biomacromolecule agents
|
US20180085398A1
(en)
|
2015-03-30 |
2018-03-29 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods of treating cancer
|
MA41867A
(fr)
|
2015-04-01 |
2018-02-06 |
Anaptysbio Inc |
Anticorps dirigés contre l'immunoglobuline de cellule t et protéine 3 de mucine (tim-3)
|
US20180153986A1
(en)
|
2015-04-24 |
2018-06-07 |
The Brigham And Women's Hospital, Inc. |
Interactions between ceacam and tim family members
|
WO2016171722A1
(fr)
|
2015-04-24 |
2016-10-27 |
The Brigham And Women's Hospital, Inc. |
Interactions entre des membres de la famille ceacam et tim
|
US20180162913A1
(en)
|
2015-05-01 |
2018-06-14 |
Immunovaccine Technologies Inc. |
Methods for potentiating an immune response using depot-forming and non-depot-forming vaccines
|
WO2016179194A1
(fr)
|
2015-05-04 |
2016-11-10 |
Jounce Therapeutics, Inc. |
Lilra3 et son procédé d'utilisation
|
WO2016180781A1
(fr)
|
2015-05-08 |
2016-11-17 |
Michele Maio |
Polythérapie du mésothéliome
|
SG10201912485PA
(en)
|
2015-05-13 |
2020-02-27 |
Agenus Inc |
Vaccines for treatment and prevention of cancer
|
TWI715587B
(zh)
|
2015-05-28 |
2021-01-11 |
美商安可美德藥物股份有限公司 |
Tigit結合劑和彼之用途
|
GB201509338D0
(en)
|
2015-05-29 |
2015-07-15 |
Bergenbio As |
Combination therapy
|
AU2016275574B2
(en)
|
2015-06-11 |
2019-07-11 |
Bionomics Limited |
Pharmaceutical combination and uses thereof
|
LT3313441T
(lt)
|
2015-06-24 |
2024-05-27 |
Janssen Biotech, Inc. |
Imuniteto moduliavimas ir solidinių navikų gydymas antikūnais, kurie specifiškai suriša cd38
|
EP3217993A1
(fr)
|
2015-07-20 |
2017-09-20 |
Virttu Biologics Limited |
Traitement du cancer par perfusion du virus de l'herpès simplex oncolytique dans le sang
|
WO2017019767A1
(fr)
|
2015-07-27 |
2017-02-02 |
Myosotis, Llc |
Inhibition de cxcl12 dans l'immunothérapie anticancéreuse
|
EP3316902A1
(fr)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Polythérapies comprenant des molécules d'anticorps contre tim -3
|
AU2016303485A1
(en)
|
2015-07-31 |
2018-03-01 |
Tarveda Therapeutics, Inc. |
Compositions and methods for immunomodulation
|
JO3620B1
(ar)
|
2015-08-05 |
2020-08-27 |
Amgen Res Munich Gmbh |
مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم
|
WO2017025871A1
(fr)
|
2015-08-07 |
2017-02-16 |
Glaxosmithkline Intellectual Property Development Limited |
Polythérapie comprenant des anticorps anti-ctla-4
|
EP3334465A1
(fr)
|
2015-08-12 |
2018-06-20 |
Bayer Pharma Aktiengesellschaft |
Combinaison pharmaceutique pour le traitement du cancer
|
WO2017030823A2
(fr)
|
2015-08-14 |
2017-02-23 |
Merck Sharp & Dohme Corp. |
Anticorps anti-tigit
|
WO2017031242A1
(fr)
|
2015-08-20 |
2017-02-23 |
Sutro Biopharma, Inc. |
Anticorps anti-tim-3, compositions comprenant des anticorps anti-tim-3 et procédés de production et d'utilisation d'anticorps anti-tim-3
|
WO2017040666A2
(fr)
|
2015-08-31 |
2017-03-09 |
Oncomed Pharmaceuticals, Inc. |
Polythérapie pour le traitement d'une maladie
|
BR112018005862A2
(pt)
|
2015-09-25 |
2018-10-16 |
Genentech, Inc. |
anticorpos, anticorpos isolados, polinucleotídeo, vetor, célula hospedeira, método de produção do anticorpo, imunoconjugado, composição, usos dos anticorpos, métodos para tratar ou retardar a progressão de um câncer e de uma doença e para aumentar, potencializar ou estimular uma resposta ou função imune e kit
|
EP3356413B1
(fr)
|
2015-10-01 |
2022-01-05 |
Potenza Therapeutics, Inc. |
Protéines de liaison à un antigène anti-tigit et leurs méthodes d'utilisation
|
BR112018006689A2
(pt)
|
2015-10-02 |
2018-10-09 |
Dana Farber Cancer Inst Inc |
terapia de combinação de inibidores de bromodomínio e bloqueio de ponto de controle
|
LT3356411T
(lt)
|
2015-10-02 |
2021-09-10 |
F. Hoffmann-La Roche Ag |
Bispecifiniai antikūnai, specifiniai pd1 ir tim3
|
WO2017055393A1
(fr)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Molécules bispécifiques de liaison à l'antigène activant les lymphocytes t anti-cd3xtim-3
|
JP6954648B2
(ja)
|
2015-10-19 |
2021-10-27 |
シージー オンコロジー, インコーポレイテッド |
併用療法による固形腫瘍又はリンパ系腫瘍の治療方法
|
CA3002711A1
(fr)
|
2015-10-22 |
2017-04-27 |
Ablynx Nv |
Agonistes de gitr
|
JP2019500893A
(ja)
|
2015-11-03 |
2019-01-17 |
ヤンセン バイオテツク,インコーポレーテツド |
Pd−1及びtim−3に特異的に結合する抗体及びそれらの使用
|
US20180346571A1
(en)
|
2015-11-17 |
2018-12-06 |
Oncomed Pharmaceuticals, Inc. |
Pd-l1-binding agents and uses thereof
|
EP3389711A1
(fr)
*
|
2015-12-18 |
2018-10-24 |
Novartis AG |
Anticorps ciblant cd32b et leurs procédés d'utilisation associés
|
BR112018074463A2
(pt)
*
|
2016-05-27 |
2019-03-06 |
Agenus Inc. |
anticorpos anti-tim-3 e métodos de uso dos mesmos.
|
CN110023337B
(zh)
*
|
2016-10-11 |
2024-01-05 |
艾吉纳斯公司 |
抗lag-3抗体及其使用方法
|
WO2018089628A1
(fr)
|
2016-11-09 |
2018-05-17 |
Agenus Inc. |
Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
|
US20230416367A1
(en)
*
|
2022-06-07 |
2023-12-28 |
Incyte Corporation |
Combination therapy of anti-pd-1 active agent, anti-tim-3 active agent, and anti-lag-3 active agent for treating cancer
|