MA43400A - Dérivés de phényle en tant qu'agonistes du récepteur cannabinoïde 2 - Google Patents

Dérivés de phényle en tant qu'agonistes du récepteur cannabinoïde 2

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Publication number
MA43400A
MA43400A MA43400A MA43400A MA43400A MA 43400 A MA43400 A MA 43400A MA 43400 A MA43400 A MA 43400A MA 43400 A MA43400 A MA 43400A MA 43400 A MA43400 A MA 43400A
Authority
MA
Morocco
Prior art keywords
cannabinoid
receptor agonists
phenyl derivatives
sup
phenyl
Prior art date
Application number
MA43400A
Other languages
English (en)
Other versions
MA43400B1 (fr
Inventor
Olivier Gavelle
Uwe Grether
Matthias Nettekoven
Stephan Roever
Mark Rogers-Evans
Didier Rombach
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA43400A publication Critical patent/MA43400A/fr
Publication of MA43400B1 publication Critical patent/MA43400B1/fr

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    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
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Abstract

L'invention porte sur un composé de formule (i) dans laquelle r<sup>1</sup> à r<sup>3</sup> sont tels que définis dans la description et dans les revendications. Le composé de formule (i) peut être utilisé comme médicament.
MA43400A 2015-12-09 2016-12-06 Dérivés de phényle en tant qu'agonistes du récepteur cannabinoïde 2 MA43400B1 (fr)

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KR100929376B1 (ko) * 2009-01-21 2009-12-02 (주)둔포기계 스퍼터링 장치
BR112018011562B1 (pt) * 2015-12-09 2023-05-02 F. Hoffmann-La Roche Ag Novos derivados de fenil
CN110753690B (zh) 2017-06-20 2023-12-05 豪夫迈·罗氏有限公司 吡啶衍生物
MA53002A (fr) 2018-06-27 2021-05-05 Eth Zuerich Nouveaux composés de pyridine et de pyrazine en tant qu'inhibiteurs du récepteur cannabinoïde 2
JP7454512B2 (ja) 2018-06-27 2024-03-22 エフ． ホフマン－ラ ロシュ アーゲー 優先的カンナビノイド２アゴニストとしてのピリジン及びピラジン誘導体
WO2020002314A1 (fr) 2018-06-27 2020-01-02 F. Hoffmann-La Roche Ag Ligand du récepteur cannabinoïde 2 radiomarqué
NO20200333A1 (en) * 2020-03-20 2021-03-29 Axichem As Synthesis of capsaicin derivatives
WO2023136263A1 (fr) 2022-01-12 2023-07-20 住友電気工業株式会社 Câble à fibre optique

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BR112018011562B1 (pt) * 2015-12-09 2023-05-02 F. Hoffmann-La Roche Ag Novos derivados de fenil

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PL3386951T3 (pl) 2020-06-29
ZA201802449B (en) 2019-01-30
CN108349901A (zh) 2018-07-31
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TW201722907A (zh) 2017-07-01
KR20180091066A (ko) 2018-08-14
UA122591C2 (uk) 2020-12-10
CO2018004573A2 (es) 2018-06-12
IL258127B (en) 2020-06-30
AU2021203482A1 (en) 2021-07-01
AU2021203482B2 (en) 2023-02-09
SI3386951T1 (sl) 2020-07-31
MX2018006802A (es) 2018-09-05
WO2017097732A1 (fr) 2017-06-15
LT3386951T (lt) 2020-05-11
RU2728823C1 (ru) 2020-07-31
MA43400B1 (fr) 2020-05-29
EP3386951B1 (fr) 2020-02-26
JP2022003066A (ja) 2022-01-11
AU2016368475A1 (en) 2018-04-12
CL2018001493A1 (es) 2018-09-14
IL258127A (en) 2018-05-31
PT3386951T (pt) 2020-04-24
US20210171441A1 (en) 2021-06-10
CR20180298A (es) 2018-07-18
US20180290966A1 (en) 2018-10-11
BR112018011562A2 (pt) 2018-11-27
MY195889A (en) 2023-02-27
HRP20200606T1 (hr) 2020-07-10
BR112018011562B1 (pt) 2023-05-02
RS60160B1 (sr) 2020-05-29
TWI812944B (zh) 2023-08-21
HK1257166A1 (zh) 2019-10-18
CN108349901B (zh) 2022-08-16
PH12018501181A1 (en) 2019-01-28
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US11339120B2 (en) 2022-05-24
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