CL2018001493A1 - Nuevos derivados de fenilo - Google Patents

Nuevos derivados de fenilo

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Publication number
CL2018001493A1
CL2018001493A1 CL2018001493A CL2018001493A CL2018001493A1 CL 2018001493 A1 CL2018001493 A1 CL 2018001493A1 CL 2018001493 A CL2018001493 A CL 2018001493A CL 2018001493 A CL2018001493 A CL 2018001493A CL 2018001493 A1 CL2018001493 A1 CL 2018001493A1
Authority
CL
Chile
Prior art keywords
phenyl derivatives
new phenyl
new
formula
derivatives
Prior art date
Application number
CL2018001493A
Other languages
English (en)
Inventor
Mark Rogers-Evans
Olivier Gavelle
Uwe Grether
Matthias Nettekoven
Stephan Roever
Didier Rombach
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CL2018001493A1 publication Critical patent/CL2018001493A1/es

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    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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    • C07C235/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
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    • C07D305/08—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring atoms
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract

LA INVENCIÓN SE REFIERE A UN COMPUESTO DE LA FÓRMULA (I), EN LA QUE DE R1 A R3 TIENEN LOS SIGNIFICADOS DEFINIDOS EN LA DESCRIPCIÓN Y EN LAS REIVINDICACIONES. EL COMPUESTO DE LA FÓRMULA (I) PUEDE EMPLEARSE COMO MEDICAMENTO.
CL2018001493A 2015-12-09 2018-06-04 Nuevos derivados de fenilo CL2018001493A1 (es)

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JP7300398B2 (ja) 2017-06-20 2023-06-29 エフ． ホフマン－ラ ロシュ アーゲー ピリジン誘導体
CN112074513A (zh) 2018-06-27 2020-12-11 豪夫迈·罗氏有限公司 作为优先大麻素2激动剂的吡啶和吡嗪衍生物
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