LT3386951T - Fenilo dariniai kaip 2 tipo kanabinoidų receptorių agonistai - Google Patents
Fenilo dariniai kaip 2 tipo kanabinoidų receptorių agonistaiInfo
- Publication number
- LT3386951T LT3386951T LTEP16805856.8T LT16805856T LT3386951T LT 3386951 T LT3386951 T LT 3386951T LT 16805856 T LT16805856 T LT 16805856T LT 3386951 T LT3386951 T LT 3386951T
- Authority
- LT
- Lithuania
- Prior art keywords
- agonists
- cannabinoid receptor
- phenyl derivatives
- phenyl
- derivatives
- Prior art date
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- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
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EP15198733 | 2015-12-09 | ||
PCT/EP2016/079825 WO2017097732A1 (en) | 2015-12-09 | 2016-12-06 | Phenyl derivatives as cannabinoid receptor 2 agonists |
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LT3386951T true LT3386951T (lt) | 2020-05-11 |
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LTEP16805856.8T LT3386951T (lt) | 2015-12-09 | 2016-12-06 | Fenilo dariniai kaip 2 tipo kanabinoidų receptorių agonistai |
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KR100929376B1 (ko) * | 2009-01-21 | 2009-12-02 | (주)둔포기계 | 스퍼터링 장치 |
CR20180298A (es) * | 2015-12-09 | 2018-07-18 | Hoffmann La Roche | Nuevos derivados de fenilo |
EP3642200B1 (en) | 2017-06-20 | 2023-05-03 | F. Hoffmann-La Roche AG | Pyridine derivatives |
CN112638430B (zh) | 2018-06-27 | 2023-05-16 | 豪夫迈·罗氏有限公司 | 放射性标记的大麻素受体2配体 |
PE20210368A1 (es) | 2018-06-27 | 2021-02-26 | Eth Zuerich | Nuevos compuestos de piridina y pirazina como inhibidores del receptor cannabinoide 2 |
WO2020002270A1 (en) | 2018-06-27 | 2020-01-02 | F. Hoffmann-La Roche Ag | Pyridine and pyrazine derivatives as preferential cannabinoid 2 agonists |
NO345530B1 (en) * | 2020-03-20 | 2021-03-29 | Axichem As | Synthesis of capsaicin derivatives |
JPWO2023136263A1 (lt) | 2022-01-12 | 2023-07-20 |
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DE10102322A1 (de) * | 2001-01-19 | 2002-07-25 | Merck Patent Gmbh | Phenylderivate |
TW200745096A (en) * | 2005-08-23 | 2007-12-16 | Organon Nv | Indole derivatives |
PL2003132T3 (pl) | 2006-04-03 | 2014-10-31 | Astellas Pharma Inc | Pochodne oksadiazolu jako agoniści S1P1 |
RU2425832C2 (ru) * | 2006-04-03 | 2011-08-10 | Астеллас Фарма Инк. | Гетеросоединение |
US9321727B2 (en) * | 2011-06-10 | 2016-04-26 | Hoffmann-La Roche Inc. | Pyridine derivatives as agonists of the CB2 receptor |
US9403808B2 (en) * | 2011-10-28 | 2016-08-02 | Hoffmann-La Roche Inc. | Pyrazine derivatives |
MX2015007155A (es) * | 2012-12-07 | 2015-10-14 | Hoffmann La Roche | Nuevos derivados de piridina. |
PE20151089A1 (es) * | 2012-12-07 | 2015-08-06 | Hoffmann La Roche | Piridin-2-amidas utiles como agonistas de cb2 |
MX2015007156A (es) * | 2012-12-07 | 2015-10-14 | Hoffmann La Roche | Piridina-2-amidas utiles como agonistas receptores de canabinoides 2 (cb2). |
IN2015DN03145A (lt) * | 2012-12-07 | 2015-10-02 | Hoffmann La Roche | |
BR112015024272A2 (pt) * | 2013-03-26 | 2017-07-18 | Hoffmann La Roche | novos derivados de piridina |
AR099932A1 (es) * | 2014-04-04 | 2016-08-31 | Hoffmann La Roche | Derivados de piridina |
PE20161370A1 (es) | 2014-04-04 | 2016-12-17 | Hoffmann La Roche | Nuevos derivados de piridina utiles como antagonistas de cb2 |
CN204999979U (zh) * | 2015-08-05 | 2016-01-27 | 林信涌 | 电解装置 |
CR20180298A (es) * | 2015-12-09 | 2018-07-18 | Hoffmann La Roche | Nuevos derivados de fenilo |
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2020
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2021
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