MA42701B1 - Compositions d'insuline à action rapide - Google Patents
Compositions d'insuline à action rapideInfo
- Publication number
- MA42701B1 MA42701B1 MA42701A MA42701A MA42701B1 MA 42701 B1 MA42701 B1 MA 42701B1 MA 42701 A MA42701 A MA 42701A MA 42701 A MA42701 A MA 42701A MA 42701 B1 MA42701 B1 MA 42701B1
- Authority
- MA
- Morocco
- Prior art keywords
- acting insulin
- rapid acting
- insulin compositions
- insulin
- analogue
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
Abstract
L'invention concerne une composition pharmaceutique d'insuline humaine ou d'analogue d'insuline, qui comprend du citrate, du tréprostinil et des agents de stabilisation, qui a une action pharmacocinétique et/ou pharmacodynamique plus rapide que des formulations commerciales de produits analogues d'insuline existants, et qui est stable pour une utilisation commerciale.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562210469P | 2015-08-27 | 2015-08-27 | |
PCT/US2016/047723 WO2017034956A1 (fr) | 2015-08-27 | 2016-08-19 | Compositions d'insuline à action rapide |
Publications (2)
Publication Number | Publication Date |
---|---|
MA42701A MA42701A (fr) | 2018-07-04 |
MA42701B1 true MA42701B1 (fr) | 2023-01-31 |
Family
ID=57003563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA42701A MA42701B1 (fr) | 2015-08-27 | 2016-08-19 | Compositions d'insuline à action rapide |
Country Status (39)
Country | Link |
---|---|
US (3) | US9901623B2 (fr) |
EP (2) | EP3340966B1 (fr) |
JP (2) | JP6359780B2 (fr) |
KR (1) | KR102018998B1 (fr) |
CN (1) | CN107920992B (fr) |
AR (1) | AR105712A1 (fr) |
AU (1) | AU2016310475B2 (fr) |
BR (1) | BR112018001755A2 (fr) |
CA (1) | CA2994427C (fr) |
CL (1) | CL2018000503A1 (fr) |
CO (1) | CO2018002026A2 (fr) |
CR (1) | CR20180118A (fr) |
DK (1) | DK3340966T3 (fr) |
DO (1) | DOP2018000059A (fr) |
EA (1) | EA033396B1 (fr) |
EC (1) | ECSP18014922A (fr) |
ES (1) | ES2928664T3 (fr) |
FI (1) | FI3340966T3 (fr) |
HR (1) | HRP20221367T1 (fr) |
HU (1) | HUE060626T2 (fr) |
IL (1) | IL256939B (fr) |
JO (1) | JO3749B1 (fr) |
LT (1) | LT3340966T (fr) |
MA (1) | MA42701B1 (fr) |
MD (1) | MD3340966T2 (fr) |
MX (1) | MX2018002482A (fr) |
MY (1) | MY195781A (fr) |
NZ (1) | NZ739338A (fr) |
PE (1) | PE20180782A1 (fr) |
PH (1) | PH12018500422B1 (fr) |
PL (1) | PL3340966T3 (fr) |
PT (1) | PT3340966T (fr) |
RS (1) | RS63731B1 (fr) |
SV (1) | SV2018005643A (fr) |
TN (1) | TN2018000056A1 (fr) |
TW (1) | TWI614025B (fr) |
UA (1) | UA120142C2 (fr) |
WO (1) | WO2017034956A1 (fr) |
ZA (1) | ZA201800511B (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA034393B1 (ru) | 2012-11-13 | 2020-02-03 | Адосиа | Состав инсулина быстрого действия, содержащий замещенное анионное соединение |
AR102869A1 (es) * | 2014-12-16 | 2017-03-29 | Lilly Co Eli | Composiciones de insulina de rápida acción |
JO3749B1 (ar) * | 2015-08-27 | 2021-01-31 | Lilly Co Eli | تركيبات إنسولين سريعة المفعول |
GB201607918D0 (en) | 2016-05-06 | 2016-06-22 | Arecor Ltd | Novel formulations |
EA201992351A1 (ru) * | 2017-06-01 | 2020-03-26 | Эли Лилли Энд Компани | Быстродействующие композиции инсулина |
US11510967B2 (en) | 2017-09-08 | 2022-11-29 | Eli Lilly And Company | Pharmaceutical combinations comprising insulin and at least an agent selected from meloxicam, bromfenac sodium, acetylsalicylic acid, salicyclic acid and paracetamol |
US20210038506A1 (en) * | 2018-04-04 | 2021-02-11 | Arecor Limited | Medical infusion pump system for the delivery of an insulin compound |
WO2019193349A1 (fr) * | 2018-04-04 | 2019-10-10 | Arecor Limited | Système de pompe à perfusion médicale pour l'administration d'un composé d'insuline |
US20210113763A1 (en) * | 2018-04-04 | 2021-04-22 | Arecor Limited | Medical infusion pump system for the delivery of an insulin compound |
FR3083985A1 (fr) | 2018-07-23 | 2020-01-24 | Adocia | Dispositif pour injecter une solution d'insuline(s) |
WO2019243627A1 (fr) | 2018-06-23 | 2019-12-26 | Adocia | Dispositif pour injecter une solution d'insuline(s) |
FR3083984A1 (fr) | 2018-07-23 | 2020-01-24 | Adocia | Dispositif pour injecter une solution d'insuline(s) |
EA202190552A1 (ru) * | 2018-09-18 | 2021-06-18 | Эли Лилли Энд Компани | Эрбуминовая соль трепростинила |
EP3996679B1 (fr) * | 2019-07-12 | 2023-09-06 | Novo Nordisk A/S | Formulation d'insuline à concentration élevée |
CN115697379A (zh) * | 2020-06-30 | 2023-02-03 | 江苏恒瑞医药股份有限公司 | 速效胰岛素组合物及其医药用途 |
Family Cites Families (60)
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EP0018609B1 (fr) | 1979-04-30 | 1983-09-21 | Hoechst Aktiengesellschaft | Solutions aqueuses de protéines, stables à la dénaturation, procédé pour leur fabrication et leur utilisation |
ZA821243B (en) * | 1981-03-10 | 1983-01-26 | Novo Industri As | Stabilized insulin preparation and method for their production |
FI78616C (fi) | 1982-02-05 | 1989-09-11 | Novo Industri As | Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt. |
PH25772A (en) | 1985-08-30 | 1991-10-18 | Novo Industri As | Insulin analogues, process for their preparation |
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AU612141B2 (en) | 1987-02-25 | 1991-07-04 | Novo Nordisk A/S | Novel insulin derivatives |
JPH04502465A (ja) | 1988-12-23 | 1992-05-07 | ノボ ノルディスク アクティーゼルスカブ | ヒトインシュリン類似物質 |
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ES2360182T3 (es) | 2002-05-07 | 2011-06-01 | Novo Nordisk A/S | Formulaciones solubles que comprenden insulina monomérica e insulina acilada. |
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TWI451876B (zh) * | 2008-06-13 | 2014-09-11 | Lilly Co Eli | 聚乙二醇化之離脯胰島素化合物 |
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US20150174209A1 (en) | 2012-05-25 | 2015-06-25 | Amylin Pharmaceuticals. Llc | Insulin-pramlintide compositions and methods for making and using them |
US20150065423A1 (en) * | 2013-08-30 | 2015-03-05 | Perosphere, Inc. | Rapid acting injectable formulations |
KR102351111B1 (ko) | 2014-01-13 | 2022-01-14 | 써멀린 다이어비티즈, 엘엘씨 | 초속효성 인슐린 제형 및 약제학적 전달 시스템 |
WO2015120457A1 (fr) * | 2014-02-10 | 2015-08-13 | Biodel Inc. | Formulations d'insuline à action ultrarapide stabilisées |
JO3624B1 (ar) * | 2014-05-08 | 2020-08-27 | Lilly Co Eli | تركيبات إنسولين سريعة المفعول |
AR102869A1 (es) | 2014-12-16 | 2017-03-29 | Lilly Co Eli | Composiciones de insulina de rápida acción |
US20180221385A1 (en) | 2015-07-28 | 2018-08-09 | Societe De Commercialisation Des Produits De La Recherche Appliquee Socpra Sciences Sante Et | A pharmaceutical preparation for improving absorption and postprandial hypoglycemic action of insulin |
JO3749B1 (ar) * | 2015-08-27 | 2021-01-31 | Lilly Co Eli | تركيبات إنسولين سريعة المفعول |
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2016
- 2016-08-14 JO JOP/2016/0183A patent/JO3749B1/ar active
- 2016-08-16 TW TW105126161A patent/TWI614025B/zh active
- 2016-08-16 AR ARP160102504A patent/AR105712A1/es unknown
- 2016-08-19 HR HRP20221367TT patent/HRP20221367T1/hr unknown
- 2016-08-19 CA CA2994427A patent/CA2994427C/fr active Active
- 2016-08-19 KR KR1020187005546A patent/KR102018998B1/ko active IP Right Grant
- 2016-08-19 BR BR112018001755-8A patent/BR112018001755A2/pt active Search and Examination
- 2016-08-19 JP JP2017545409A patent/JP6359780B2/ja active Active
- 2016-08-19 EP EP16771021.9A patent/EP3340966B1/fr active Active
- 2016-08-19 US US15/241,412 patent/US9901623B2/en active Active
- 2016-08-19 PL PL16771021.9T patent/PL3340966T3/pl unknown
- 2016-08-19 MA MA42701A patent/MA42701B1/fr unknown
- 2016-08-19 RS RS20221041A patent/RS63731B1/sr unknown
- 2016-08-19 DK DK16771021.9T patent/DK3340966T3/da active
- 2016-08-19 WO PCT/US2016/047723 patent/WO2017034956A1/fr active Application Filing
- 2016-08-19 EA EA201890343A patent/EA033396B1/ru unknown
- 2016-08-19 LT LTEPPCT/US2016/047723T patent/LT3340966T/lt unknown
- 2016-08-19 AU AU2016310475A patent/AU2016310475B2/en active Active
- 2016-08-19 TN TNP/2018/000056A patent/TN2018000056A1/en unknown
- 2016-08-19 ES ES16771021T patent/ES2928664T3/es active Active
- 2016-08-19 MX MX2018002482A patent/MX2018002482A/es unknown
- 2016-08-19 HU HUE16771021A patent/HUE060626T2/hu unknown
- 2016-08-19 CR CR20180118A patent/CR20180118A/es unknown
- 2016-08-19 FI FIEP16771021.9T patent/FI3340966T3/fi active
- 2016-08-19 UA UAA201801732A patent/UA120142C2/uk unknown
- 2016-08-19 PE PE2018000246A patent/PE20180782A1/es unknown
- 2016-08-19 MD MDE20180654T patent/MD3340966T2/ro unknown
- 2016-08-19 NZ NZ739338A patent/NZ739338A/en unknown
- 2016-08-19 EP EP22200405.3A patent/EP4169505A1/fr not_active Withdrawn
- 2016-08-19 PT PT167710219T patent/PT3340966T/pt unknown
- 2016-08-19 MY MYPI2018700714A patent/MY195781A/en unknown
- 2016-08-19 CN CN201680048530.0A patent/CN107920992B/zh active Active
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2018
- 2018-01-11 US US15/868,272 patent/US10925931B2/en active Active
- 2018-01-15 IL IL25693918A patent/IL256939B/en active IP Right Grant
- 2018-01-24 ZA ZA2018/00511A patent/ZA201800511B/en unknown
- 2018-02-23 DO DO2018000059A patent/DOP2018000059A/es unknown
- 2018-02-23 CO CONC2018/0002026A patent/CO2018002026A2/es unknown
- 2018-02-26 CL CL2018000503A patent/CL2018000503A1/es unknown
- 2018-02-26 PH PH12018500422A patent/PH12018500422B1/en unknown
- 2018-02-27 SV SV2018005643A patent/SV2018005643A/es unknown
- 2018-02-27 EC ECIEPI201814922A patent/ECSP18014922A/es unknown
- 2018-06-20 JP JP2018117015A patent/JP6935364B2/ja active Active
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2021
- 2021-02-19 US US17/180,100 patent/US20210169988A1/en active Pending
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