CO2018002026A2 - Composiciones de insulina de rápida acción - Google Patents

Composiciones de insulina de rápida acción

Info

Publication number
CO2018002026A2
CO2018002026A2 CONC2018/0002026A CO2018002026A CO2018002026A2 CO 2018002026 A2 CO2018002026 A2 CO 2018002026A2 CO 2018002026 A CO2018002026 A CO 2018002026A CO 2018002026 A2 CO2018002026 A2 CO 2018002026A2
Authority
CO
Colombia
Prior art keywords
rapid
acting insulin
insulin compositions
insulin analog
insulin
Prior art date
Application number
CONC2018/0002026A
Other languages
English (en)
Inventor
Michael Edward Christe
Thomas Andrew Hardy
Michael Patrick Akers
Ranajoy Majumdar
Chi A Nguyen
Chad D Paavola
Virender Kumar Sarin
Nanette Elizabeth Schulte
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57003563&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO2018002026(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CO2018002026A2 publication Critical patent/CO2018002026A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Abstract

La presente invención se refiere a una composición farmacéutica de insulina humana o análogo de insulina que incluye citrato, treprostinilo y agentes estabilizantes, que tiene acción farmacocinética y farmacodinámica más rápida que las formulaciones comerciales de productos análogos de insulina existentes y que es estable para uso comercial.
CONC2018/0002026A 2015-08-27 2018-02-23 Composiciones de insulina de rápida acción CO2018002026A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562210469P 2015-08-27 2015-08-27
PCT/US2016/047723 WO2017034956A1 (en) 2015-08-27 2016-08-19 Rapid-acting insulin compositions

Publications (1)

Publication Number Publication Date
CO2018002026A2 true CO2018002026A2 (es) 2018-05-21

Family

ID=57003563

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2018/0002026A CO2018002026A2 (es) 2015-08-27 2018-02-23 Composiciones de insulina de rápida acción

Country Status (39)

Country Link
US (3) US9901623B2 (es)
EP (2) EP3340966B1 (es)
JP (2) JP6359780B2 (es)
KR (1) KR102018998B1 (es)
CN (1) CN107920992B (es)
AR (1) AR105712A1 (es)
AU (1) AU2016310475B2 (es)
BR (1) BR112018001755A2 (es)
CA (1) CA2994427C (es)
CL (1) CL2018000503A1 (es)
CO (1) CO2018002026A2 (es)
CR (1) CR20180118A (es)
DK (1) DK3340966T3 (es)
DO (1) DOP2018000059A (es)
EA (1) EA033396B1 (es)
EC (1) ECSP18014922A (es)
ES (1) ES2928664T3 (es)
FI (1) FI3340966T3 (es)
HR (1) HRP20221367T1 (es)
HU (1) HUE060626T2 (es)
IL (1) IL256939B (es)
JO (1) JO3749B1 (es)
LT (1) LT3340966T (es)
MA (1) MA42701B1 (es)
MD (1) MD3340966T2 (es)
MX (1) MX2018002482A (es)
MY (1) MY195781A (es)
NZ (1) NZ739338A (es)
PE (1) PE20180782A1 (es)
PH (1) PH12018500422B1 (es)
PL (1) PL3340966T3 (es)
PT (1) PT3340966T (es)
RS (1) RS63731B1 (es)
SV (1) SV2018005643A (es)
TN (1) TN2018000056A1 (es)
TW (1) TWI614025B (es)
UA (1) UA120142C2 (es)
WO (1) WO2017034956A1 (es)
ZA (1) ZA201800511B (es)

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GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
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Also Published As

Publication number Publication date
UA120142C2 (uk) 2019-10-10
DOP2018000059A (es) 2018-04-15
TWI614025B (zh) 2018-02-11
EA033396B1 (ru) 2019-10-31
PL3340966T3 (pl) 2023-01-30
MY195781A (en) 2023-02-13
AU2016310475B2 (en) 2018-10-18
PH12018500422A1 (en) 2018-08-29
EA201890343A1 (ru) 2018-07-31
US10925931B2 (en) 2021-02-23
TW201717997A (zh) 2017-06-01
JP6935364B2 (ja) 2021-09-15
KR102018998B1 (ko) 2019-09-05
JO3749B1 (ar) 2021-01-31
JP2018507869A (ja) 2018-03-22
CN107920992B (zh) 2021-06-18
BR112018001755A2 (pt) 2018-09-18
DK3340966T3 (da) 2022-10-24
CL2018000503A1 (es) 2018-08-03
WO2017034956A1 (en) 2017-03-02
JP2018172404A (ja) 2018-11-08
MA42701A (fr) 2018-07-04
PT3340966T (pt) 2022-12-05
KR20180033276A (ko) 2018-04-02
FI3340966T3 (fi) 2023-01-13
PE20180782A1 (es) 2018-05-07
MA42701B1 (fr) 2023-01-31
ECSP18014922A (es) 2018-04-30
EP3340966A1 (en) 2018-07-04
US9901623B2 (en) 2018-02-27
HUE060626T2 (hu) 2023-03-28
ZA201800511B (en) 2019-07-31
ES2928664T3 (es) 2022-11-21
IL256939B (en) 2019-10-31
CA2994427A1 (en) 2017-03-02
US20210169988A1 (en) 2021-06-10
EP3340966B1 (en) 2022-10-12
US20180140676A1 (en) 2018-05-24
HRP20221367T1 (hr) 2023-01-06
US20170056478A1 (en) 2017-03-02
EP4169505A1 (en) 2023-04-26
PH12018500422B1 (en) 2018-08-29
IL256939A (en) 2018-03-29
MX2018002482A (es) 2018-06-15
CA2994427C (en) 2019-07-09
SV2018005643A (es) 2018-10-09
AU2016310475A1 (en) 2018-02-15
MD3340966T2 (ro) 2023-04-30
JP6359780B2 (ja) 2018-07-18
LT3340966T (lt) 2022-11-25
RS63731B1 (sr) 2022-12-30
AR105712A1 (es) 2017-11-01
CN107920992A (zh) 2018-04-17
NZ739338A (en) 2019-06-28
TN2018000056A1 (en) 2019-07-08
CR20180118A (es) 2018-03-20

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