AR105712A1 - Composiciones de insulina de rápida acción - Google Patents

Composiciones de insulina de rápida acción

Info

Publication number
AR105712A1
AR105712A1 ARP160102504A ARP160102504A AR105712A1 AR 105712 A1 AR105712 A1 AR 105712A1 AR P160102504 A ARP160102504 A AR P160102504A AR P160102504 A ARP160102504 A AR P160102504A AR 105712 A1 AR105712 A1 AR 105712A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
concentration
quick action
insulin compositions
composition according
Prior art date
Application number
ARP160102504A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57003563&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR105712(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AR105712A1 publication Critical patent/AR105712A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Abstract

Reivindicación 1: Una composición farmacéutica caracterizada porque comprende: a) una insulina; b) citrato, en una concentración desde aproximadamente 5 hasta aproximadamente 25 mM; c) treprostinilo, en una, concentración desde aproximadamente 0.04 hasta aproximadamente 20 mg/mL; d) zinc, en una concentración suficiente para proporcionar al menos 2 iones de zinc por seis moléculas de insulina; e) un preservativo; y f) uno o más agentes estabilizantes adicionales; y que tiene un pH de aproximadamente 7.0 hasta aproximadamente 7.8 a temperatura ambiente. Reivindicación 33: Un método para tratar diabetes, caracterizado porque comprende administrar a un humano en necesidad del mismo una dosis efectiva de la composición farmacéutica de conformidad con cualquiera de las reivindicaciones 1 - 32. Reivindicación 36: Uso de la composición farmacéutica de conformidad con cualquiera de las reivindicaciones 1 - 32, en la manufactura de un medicamento para el tratamiento de diabetes.
ARP160102504A 2015-08-27 2016-08-16 Composiciones de insulina de rápida acción AR105712A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562210469P 2015-08-27 2015-08-27

Publications (1)

Publication Number Publication Date
AR105712A1 true AR105712A1 (es) 2017-11-01

Family

ID=57003563

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160102504A AR105712A1 (es) 2015-08-27 2016-08-16 Composiciones de insulina de rápida acción

Country Status (39)

Country Link
US (3) US9901623B2 (es)
EP (2) EP3340966B1 (es)
JP (2) JP6359780B2 (es)
KR (1) KR102018998B1 (es)
CN (1) CN107920992B (es)
AR (1) AR105712A1 (es)
AU (1) AU2016310475B2 (es)
BR (1) BR112018001755A2 (es)
CA (1) CA2994427C (es)
CL (1) CL2018000503A1 (es)
CO (1) CO2018002026A2 (es)
CR (1) CR20180118A (es)
DK (1) DK3340966T3 (es)
DO (1) DOP2018000059A (es)
EA (1) EA033396B1 (es)
EC (1) ECSP18014922A (es)
ES (1) ES2928664T3 (es)
FI (1) FI3340966T3 (es)
HR (1) HRP20221367T1 (es)
HU (1) HUE060626T2 (es)
IL (1) IL256939B (es)
JO (1) JO3749B1 (es)
LT (1) LT3340966T (es)
MA (1) MA42701B1 (es)
MD (1) MD3340966T2 (es)
MX (1) MX2018002482A (es)
MY (1) MY195781A (es)
NZ (1) NZ739338A (es)
PE (1) PE20180782A1 (es)
PH (1) PH12018500422A1 (es)
PL (1) PL3340966T3 (es)
PT (1) PT3340966T (es)
RS (1) RS63731B1 (es)
SV (1) SV2018005643A (es)
TN (1) TN2018000056A1 (es)
TW (1) TWI614025B (es)
UA (1) UA120142C2 (es)
WO (1) WO2017034956A1 (es)
ZA (1) ZA201800511B (es)

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AR102869A1 (es) * 2014-12-16 2017-03-29 Lilly Co Eli Composiciones de insulina de rápida acción
JO3749B1 (ar) * 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
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WO2019050749A1 (en) * 2017-09-08 2019-03-14 Eli Lilly And Company PHARMACEUTICAL COMBINATIONS COMPRISING INSULIN AND AT LEAST ONE AGENT SELECTED AMONG MELOXICAM, BROMFENAC SODIUM, ACETYLSALICYLIC ACID, SALICYLIC ACID AND PARACETAMOL
US20210093775A1 (en) * 2018-04-04 2021-04-01 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
CA3094237A1 (en) * 2018-04-04 2019-10-10 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
EP3773473A1 (en) * 2018-04-04 2021-02-17 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
FR3083985A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
FR3083984A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
WO2019243627A1 (fr) 2018-06-23 2019-12-26 Adocia Dispositif pour injecter une solution d'insuline(s)
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Also Published As

Publication number Publication date
MA42701B1 (fr) 2023-01-31
NZ739338A (en) 2019-06-28
TN2018000056A1 (en) 2019-07-08
EP3340966B1 (en) 2022-10-12
ZA201800511B (en) 2019-07-31
MD3340966T2 (ro) 2023-04-30
SV2018005643A (es) 2018-10-09
FI3340966T3 (fi) 2023-01-13
TW201717997A (zh) 2017-06-01
CN107920992A (zh) 2018-04-17
PT3340966T (pt) 2022-12-05
DK3340966T3 (da) 2022-10-24
JP6359780B2 (ja) 2018-07-18
CL2018000503A1 (es) 2018-08-03
MX2018002482A (es) 2018-06-15
CN107920992B (zh) 2021-06-18
PH12018500422B1 (en) 2018-08-29
DOP2018000059A (es) 2018-04-15
LT3340966T (lt) 2022-11-25
ECSP18014922A (es) 2018-04-30
CA2994427C (en) 2019-07-09
IL256939B (en) 2019-10-31
WO2017034956A1 (en) 2017-03-02
EA033396B1 (ru) 2019-10-31
TWI614025B (zh) 2018-02-11
US10925931B2 (en) 2021-02-23
AU2016310475A1 (en) 2018-02-15
US20210169988A1 (en) 2021-06-10
US20180140676A1 (en) 2018-05-24
PL3340966T3 (pl) 2023-01-30
JO3749B1 (ar) 2021-01-31
JP2018172404A (ja) 2018-11-08
HUE060626T2 (hu) 2023-03-28
CA2994427A1 (en) 2017-03-02
JP6935364B2 (ja) 2021-09-15
HRP20221367T1 (hr) 2023-01-06
PE20180782A1 (es) 2018-05-07
PH12018500422A1 (en) 2018-08-29
BR112018001755A2 (pt) 2018-09-18
EP4169505A1 (en) 2023-04-26
MA42701A (fr) 2018-07-04
ES2928664T3 (es) 2022-11-21
IL256939A (en) 2018-03-29
CO2018002026A2 (es) 2018-05-21
EA201890343A1 (ru) 2018-07-31
RS63731B1 (sr) 2022-12-30
KR20180033276A (ko) 2018-04-02
JP2018507869A (ja) 2018-03-22
CR20180118A (es) 2018-03-20
UA120142C2 (uk) 2019-10-10
MY195781A (en) 2023-02-13
KR102018998B1 (ko) 2019-09-05
US9901623B2 (en) 2018-02-27
AU2016310475B2 (en) 2018-10-18
US20170056478A1 (en) 2017-03-02
EP3340966A1 (en) 2018-07-04

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