MA39441A1 - Composition d'insuline a action rapide - Google Patents

Composition d'insuline a action rapide

Info

Publication number
MA39441A1
MA39441A1 MA39441A MA39441A MA39441A1 MA 39441 A1 MA39441 A1 MA 39441A1 MA 39441 A MA39441 A MA 39441A MA 39441 A MA39441 A MA 39441A MA 39441 A1 MA39441 A1 MA 39441A1
Authority
MA
Morocco
Prior art keywords
fast
acting insulin
insulin composition
insulin analog
composition
Prior art date
Application number
MA39441A
Other languages
English (en)
Inventor
Micheal Edward Christe
Thomas Andrew Hardy
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53189204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA39441(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA39441A1 publication Critical patent/MA39441A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention porte sur une composition d'insuline humaine ou d'analogue d'insuline qui comprend du tréprostinil et qui possède une action pharmacocinétique plus rapide par rapport aux formulations commerciales de produits analogues d'insuline existants.
MA39441A 2014-05-08 2015-05-04 Composition d'insuline a action rapide MA39441A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461990402P 2014-05-08 2014-05-08
PCT/US2015/029010 WO2015171484A1 (fr) 2014-05-08 2015-05-04 Compositions d'insuline à action rapide

Publications (1)

Publication Number Publication Date
MA39441A1 true MA39441A1 (fr) 2017-06-30

Family

ID=53189204

Family Applications (1)

Application Number Title Priority Date Filing Date
MA39441A MA39441A1 (fr) 2014-05-08 2015-05-04 Composition d'insuline a action rapide

Country Status (36)

Country Link
US (2) US9439952B2 (fr)
EP (3) EP3140008B1 (fr)
JP (1) JP6050902B2 (fr)
KR (1) KR101858890B1 (fr)
CN (1) CN106456717B (fr)
AP (1) AP2016009525A0 (fr)
AR (1) AR100155A1 (fr)
AU (1) AU2015256355B2 (fr)
BR (1) BR112016024357B1 (fr)
CA (1) CA2945188C (fr)
CL (1) CL2016002772A1 (fr)
CY (2) CY1121669T1 (fr)
DK (2) DK3140008T3 (fr)
EA (1) EA031134B1 (fr)
ES (2) ES2733639T3 (fr)
HR (2) HRP20190777T1 (fr)
HU (2) HUE044370T2 (fr)
IL (1) IL248350B (fr)
JO (1) JO3624B1 (fr)
LT (2) LT3536380T (fr)
MA (1) MA39441A1 (fr)
ME (1) ME03384B (fr)
MX (1) MX367521B (fr)
NZ (1) NZ724919A (fr)
PE (1) PE20161408A1 (fr)
PH (1) PH12016502195B1 (fr)
PL (2) PL3140008T3 (fr)
PT (2) PT3536380T (fr)
RS (2) RS62291B1 (fr)
SG (1) SG11201608424WA (fr)
SI (2) SI3536380T1 (fr)
TN (1) TN2016000443A1 (fr)
TR (1) TR201906843T4 (fr)
TW (1) TWI685348B (fr)
UA (1) UA124919C2 (fr)
WO (1) WO2015171484A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5749155B2 (ja) 2008-03-18 2015-07-15 ノボ・ノルデイスク・エー/エス プロテアーゼ安定化アシル化インスリンアナログ
AU2013346624B2 (en) 2012-11-13 2018-08-09 Adocia Quick-acting insulin formulation including a substituted anionic compound
WO2014110491A1 (fr) 2013-01-11 2014-07-17 Theratrophix Llc Promédicaments de tréprostinil
US9505737B2 (en) 2013-01-11 2016-11-29 Corsair Pharma, Inc. Treprostinil derivative compounds and methods of using same
EP3328388B1 (fr) * 2015-07-28 2023-12-27 Eli Lilly and Company Préparation pharmaceutique pour améliorer l'absorption et l'action hypoglycémique postprandiale de l'insuline
JO3749B1 (ar) * 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
EP3407870B1 (fr) * 2016-01-29 2022-06-29 MannKind Corporation Inhalateur à poudre sèche
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
KR102541885B1 (ko) 2016-09-26 2023-06-12 유나이티드 쎄러퓨틱스 코포레이션 트레프로스티닐 프로드럭
CA3034972C (fr) 2016-09-29 2024-04-09 Arecor Limited Formulation d'insuline pharmaceutique
ES2886837T3 (es) 2016-12-16 2021-12-21 Novo Nordisk As Composiciones farmacéuticas que contienen insulina
GB201707187D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707188D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707189D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
JP6920471B2 (ja) 2017-06-01 2021-08-18 イーライ リリー アンド カンパニー 迅速に作用するインスリン組成物
EP3773474A1 (fr) 2018-04-04 2021-02-17 Arecor Limited Système de pompe à perfusion médicale pour l'administration d'un composé d'insuline
EP3773473A1 (fr) 2018-04-04 2021-02-17 Arecor Limited Système de pompe à perfusion médicale pour l'administration d'un composé d'insuline
KR20200139700A (ko) * 2018-04-04 2020-12-14 아레콜 리미티드 인슐린 화합물의 전달을 위한 의료용 주입 펌프 시스템
FR3083985A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
WO2019243627A1 (fr) 2018-06-23 2019-12-26 Adocia Dispositif pour injecter une solution d'insuline(s)
WO2020060823A1 (fr) 2018-09-18 2020-03-26 Eli Lilly And Company Sel erbumine de tréprostinil
US10799564B1 (en) 2019-05-06 2020-10-13 Baxter International Inc. Insulin premix formulation and product, methods of preparing same, and methods of using same
CN114096269B (zh) * 2019-07-12 2024-06-11 诺和诺德股份有限公司 高浓度胰岛素制剂
EP4017588A1 (fr) 2019-08-23 2022-06-29 United Therapeutics Corporation Promédicaments de tréprostinil
GB202004814D0 (en) 2020-04-01 2020-05-13 Arecor Ltd Novel formulations
IL296567A (en) 2020-04-17 2022-11-01 United Therapeutics Corp Terfostinil for use in the treatment of interstitial lung disease
WO2021252446A1 (fr) 2020-06-09 2021-12-16 United Therapeutics Corporation Promédicaments à base de fumaryle dicétopipéridine de tréprostinil
WO2022002008A1 (fr) * 2020-06-30 2022-01-06 江苏恒瑞医药股份有限公司 Composé d'insuline à action rapide et son utilisation médicale
WO2022132655A1 (fr) 2020-12-14 2022-06-23 United Therapeutics Corporation Méthodes de traitement d'une maladie à l'aide de promédicaments tréprostinil

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2740953A1 (de) 1977-09-12 1979-03-22 Thera Ges Fuer Patente Verwendung von prostaglandinen zur senkung des blutzuckerspiegels
JPH10251146A (ja) 1997-03-11 1998-09-22 Toray Ind Inc 糖尿病性神経障害の治療方法
CN1635900A (zh) * 2001-08-28 2005-07-06 伊莱利利公司 Glp-1和基础胰岛素的预混合物
AU2003236201A1 (en) * 2002-05-07 2003-11-11 Novo Nordisk A/S Soluble formulations comprising monomeric insulin and acylated insulin
DE602005020269D1 (de) * 2004-04-12 2010-05-12 United Therapeutics Corp Verwendung von treprostinil zur behandlung von neuropathischen diabetischen fussgeschwüren
EP2190433A2 (fr) * 2007-08-22 2010-06-02 Gilead Colorado, Inc. Thérapie pour complications du diabète
EP2328636B1 (fr) 2008-08-28 2013-06-12 Medingo Ltd. Dispositif permettant l'absorption sous-cutanée accrue d'insuline
EP2330893A4 (fr) * 2008-09-25 2013-01-09 Aradigm Corp Administration pulmonaire profonde de tréprostinil
ES2440289T3 (es) * 2009-06-26 2014-01-28 Novo Nordisk A/S Preparación que comprende insulina, nicotinamida y arginina
TWI513462B (zh) * 2009-11-13 2015-12-21 Toray Industries 糖尿病之治療或預防藥
RU2013130374A (ru) 2010-12-14 2015-01-20 Ново Нордиск А/С Препарат, содержащий инсулин, никотинамид и аминокислоту
WO2013024052A1 (fr) * 2011-08-12 2013-02-21 Ascendis Pharma A/S Promédicaments à base de tréprostinil lié à un excipient
US9381247B2 (en) * 2012-04-16 2016-07-05 Biodel Inc. Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
WO2015031709A1 (fr) 2013-08-30 2015-03-05 Perosphere, Inc. Formulations injectables à action rapide comprenant un peptide et un agent vasodilatateur
US20150273022A1 (en) 2014-02-10 2015-10-01 Biodel Inc. Stabilized ultra-rapid-acting insulin formulations

Also Published As

Publication number Publication date
AU2015256355A1 (en) 2016-10-27
EP3536380B1 (fr) 2021-07-07
JP6050902B2 (ja) 2016-12-21
PT3536380T (pt) 2021-09-02
EP3536380A1 (fr) 2019-09-11
EP3943155A1 (fr) 2022-01-26
HRP20211415T1 (hr) 2021-12-10
HUE044370T2 (hu) 2019-10-28
DK3140008T3 (da) 2019-06-24
RS62291B1 (sr) 2021-09-30
JP2016523807A (ja) 2016-08-12
SI3140008T1 (sl) 2019-06-28
EA201691911A1 (ru) 2017-02-28
WO2015171484A1 (fr) 2015-11-12
HRP20190777T1 (hr) 2019-08-23
CN106456717A (zh) 2017-02-22
EP3140008B1 (fr) 2019-04-17
TN2016000443A1 (en) 2018-04-04
MX367521B (es) 2019-08-26
PL3140008T3 (pl) 2019-09-30
KR101858890B1 (ko) 2018-05-16
US10172922B2 (en) 2019-01-08
PT3140008T (pt) 2019-06-25
EA031134B1 (ru) 2018-11-30
AU2015256355B2 (en) 2017-09-14
LT3536380T (lt) 2021-08-10
AP2016009525A0 (en) 2016-10-31
CY1124454T1 (el) 2022-07-22
JO3624B1 (ar) 2020-08-27
PH12016502195A1 (en) 2017-02-06
US20160367640A1 (en) 2016-12-22
CL2016002772A1 (es) 2017-06-09
PH12016502195B1 (en) 2017-02-06
ES2733639T3 (es) 2019-12-02
US20160129087A1 (en) 2016-05-12
CY1121669T1 (el) 2020-07-31
MX2016014643A (es) 2017-03-06
TW201625291A (zh) 2016-07-16
HUE055742T2 (hu) 2021-12-28
IL248350B (en) 2020-03-31
TR201906843T4 (tr) 2019-05-21
BR112016024357B1 (pt) 2022-08-23
LT3140008T (lt) 2019-05-27
PE20161408A1 (es) 2016-12-28
TWI685348B (zh) 2020-02-21
IL248350A0 (en) 2016-11-30
US9439952B2 (en) 2016-09-13
ES2891983T3 (es) 2022-02-01
PL3536380T3 (pl) 2021-12-27
CA2945188C (fr) 2018-12-11
EP3536380B8 (fr) 2021-09-22
SG11201608424WA (en) 2016-11-29
AR100155A1 (es) 2016-09-14
CN106456717B (zh) 2020-01-17
RS58726B1 (sr) 2019-06-28
NZ724919A (en) 2018-01-26
UA124919C2 (uk) 2021-12-15
ME03384B (fr) 2020-01-20
DK3536380T3 (da) 2021-08-02
CA2945188A1 (fr) 2015-11-12
EP3140008A1 (fr) 2017-03-15
SI3536380T1 (sl) 2021-09-30
KR20160133567A (ko) 2016-11-22
BR112016024357A2 (pt) 2017-10-10

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